Hypothesis

22 Matching Annotations

May 2026
link.springer.com link.springer.com

Celecoxib potentiates ribociclib-induced apoptosis and anti-tumor activity by co-targeting COX-2/NF-κB and PI3K/AKT/mTOR pathways in hormone receptor-positive/HER2-negative breast cancer

1
1. scibot 08 May 2026
  
  in Public
  
  RRID:CVCL_1252
  
  DOI: 10.1007/s10495-026-02340-z
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1252
  
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  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

link.springer.com/article/10.1007/s10495-026-02340-z
Apr 2026
www.biorxiv.org www.biorxiv.org

Advanced models of lobular breast cancer metastasis capture clinical organ tropism, endocrine response, and bone remodeling

1
1. scibot 17 Apr 2026
  
  in Public
  
  CRL-2327
  
  DOI: 10.64898/2026.03.13.711653
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_1252
  
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  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

biorxiv.org/content/10.64898/2026.03.13.711653v1
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition

1
1. scibot 14 Feb 2026
  
  in Public
  
  RRID:CVCL_1252
  
  DOI: 10.1158/0008-5472.CAN-25-1217
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1252
  
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  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12900515/
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer

1
1. scibot 17 Dec 2025
  
  in Public
  
  ATCC (American Type Culture Collection)CRL-2327
  
  DOI: 10.1016/j.xcrm.2025.102478
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1252
  
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  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

sciencedirect.com:5037/science/article/pii/S2666379125005518
Nov 2025
www.sciencedirect.com www.sciencedirect.com

Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells

1
1. scibot 13 Nov 2025
  
  in Public
  
  ATCCCat# CRL-2327
  
  DOI: 10.1016/j.xcrm.2025.102446
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1252
  
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  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

sciencedirect.com/science/article/pii/S2666379125005191
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PARP inhibitor and PRMT5 inhibitor synergy is independent of BRCA1/2 and MTAP status in breast cancer cells

1
1. scibot 25 Oct 2025
  
  in Public
  
  RRID: CVCL_1252
  
  DOI: 10.1038/s41598-025-20696-1
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1252
  
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  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12540990/
Aug 2025
www.nature.com www.nature.com

Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis

1
1. scibot 27 Aug 2025
  
  in Public
  
  CRL-2327
  
  DOI: 10.1038/s41467-025-62486-3
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_1252
  
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  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

nature.com/articles/s41467-025-62486-3
Mar 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 24 Mar 2025
  
  in Public
  
  RRID:CVCL_1252
  
  DOI: 10.1158/1535-7163.mct-24-0928
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1252
  
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  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

52.53.155.43/098761c36b4439bcc578d63b667c303f01bb0050/PDF-html.html
www.sciencedirect.com www.sciencedirect.com

CDK4 selective inhibition improves preclinical anti-tumor efficacy and safety

1
1. scibot 11 Mar 2025
  
  in Public
  
  ATCCCRL-2327
  
  DOI: 10.1016/j.ccell.2025.02.006
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825000583
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Imlunestrant Is an Oral, Brain-Penetrant Selective Estrogen Receptor Degrader with Potent Antitumor Activity in ESR1 Wild-Type and Mutant Breast Cancer

1
1. scibot 19 Feb 2025
  
  in Public
  
  RRID:CVCL_1252
  
  DOI: 10.1158/0008-5472.CAN-24-2608
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11831106/
Dec 2024
52.53.155.43 52.53.155.43

can-24-2608-html.html

1
1. scibot 13 Dec 2024
  
  in Public
  
  RRID:CVCL_1252
  
  DOI: 10.1158/0008-5472.can-24-2608
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

52.53.155.43/cf584dc99a64cef80bea76148546097bcf5b8be7/can-24-2608-html.html
Sep 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

Dynamic methylation and expression of alternative promoters for oestrogen receptor alpha in cell line models of fulvestrant resistance

1
1. scibot 27 Sep 2024
  
  in Public
  
  RRID:CVCL_1252
  
  DOI: 10.1002/1878-0261.13713
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252 DOI:10.1002/1878-0261.13713
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DOI:10.1002/1878-0261.13713

RRID:CVCL_1252

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scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13713
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours

1
1. scibot 23 Aug 2024
  
  in Public
  
  RRID:CVCL_1252
  
  DOI: 10.1158/2767-9764.CRC-24-0113
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11320025/
www.cell.com www.cell.com

ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines

1
1. scibot 13 Aug 2024
  
  in Public
  
  CRL-2327
  
  DOI: 10.1016/j.celrep.2024.114433
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

cell.com/cell-reports/fulltext/S2211-1247(24)00762-9
Sep 2023
aacrjournals.org aacrjournals.org

Nanoparticle-based combination therapy enhances fulvestrant efficacy and overcomes tumor resistance in ER-positive breast cancer

1
1. scibot 15 Sep 2023
  
  in Public
  
  RRID:CVCL_1252
  
  DOI: 10.1158/0008-5472.CAN-22-3559
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

aacrjournals.org/cancerres/article/83/17/2924/728581/Nanoparticle-Based-Combination-Therapy-Enhances
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor

1
1. scibot 14 Sep 2021
  
  in Public
  
  CRL-2327
  
  DOI: 10.1016/j.ccell.2021.08.009
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1252

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scibot

URL

sciencedirect.com/science/article/pii/S1535610821004499
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

1
1. scibot 01 Aug 2021
  
  in Public
  
  CVCL_1252
  
  DOI: 10.1016/j.cels.2019.11.001
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1252
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RRIDCUR:Validated

RRID:CVCL_1252

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scibot

URL

sciencedirect.com/science/article/pii/S2405471219303874
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer

1
1. scibot 29 Jul 2021
  
  in Public
  
  HCC1428
  
  DOI: 10.1016/j.celrep.2019.06.010
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1252

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719307685
www.sciencedirect.com www.sciencedirect.com

Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID: CVCL_1252
  
  DOI: 10.1016/j.chembiol.2019.05.005
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252
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RRID:CVCL_1252

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scibot

URL

sciencedirect.com/science/article/pii/S2451945619301746
May 2021
www.sciencedirect.com www.sciencedirect.com

Deciphering the signaling network of breast cancer improves drug sensitivity prediction

1
1. scibot 01 May 2021
  
  in Public
  
  CRL-2327
  
  DOI: 10.1016/j.cels.2021.04.002
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRID:CVCL_1252 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1252

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scibot

URL

sciencedirect.com/science/article/pii/S2405471221001113
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:CVCL_1252
  
  DOI: 10.1016/j.cell.2020.05.053
  
  Resource: (ATCC Cat# CRL-2327, RRID:CVCL_1252)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1252
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1252
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RRIDCUR:Validated

RRID:CVCL_1252

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scibot

URL

sciencedirect.com/science/article/pii/S0092867420306863
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL2327
  
  Curator: @Jmenke
  
  Resource used:
  
  (KCLB Cat# 9S1428, RRID:CVCL_1252)
  
  SciCrunch record: RRID:CVCL_1252
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1252 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1252

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scibot

URL

sciencedirect.com/science/article/pii/S0092867418303088