113 Matching Annotations
  1. Sep 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Cyclin E-CDK2 regulates cancer cell transcriptional program and response to immunotherapy through BRD4
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    sciencedirect.com/science/article/pii/S109727652600554X
  3. www.sciencedirect.com www.sciencedirect.com
    Lysyl oxidase inhibition disrupts mitochondrial homeostasis to create vulnerability to ferroptosis in TNBC
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    sciencedirect.com/science/article/pii/S2666379126004325
  4. Aug 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glycolytic enolase 1-induced H4K12 lactylation activates quiescent breast cancer stem-like cells in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13493833/
  6. Jul 2026
  7. www.sciencedirect.com www.sciencedirect.com
    An antibody-PROTAC conjugate targets BRD4/c-Myc/PD-L1 to enhance immunotherapy efficacy in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379126003654
  8. Jun 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cyclin E modulates vulnerability to CDC7 kinase inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC13243581/
  10. Apr 2026
  11. aacrjournals.org aacrjournals.org
    Epigenetic regulation of chromosomal instability by EZH2 methyltransferase.
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    aacrjournals.org/cancerdiscovery/article/16/1/135/771226/Epigenetic-Regulation-of-Chromosomal-Instability
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Payload Diversification Overcomes Resistance and Guides Sequential Antibody-Drug Conjugate Therapy in Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055631/
  13. Mar 2026
  14. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70144
  15. www.sciencedirect.com www.sciencedirect.com
    AK5 suppresses breast cancer progression and modulates anti-PD-L1 efficacy via the miR-182-5p/PD-L1 axis
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    sciencedirect.com/science/article/pii/S2589004226006358
  16. www.sciencedirect.com www.sciencedirect.com
    Comprehensive single-cell metabolic profiling identifies targets to sensitize triple-negative breast cancer to chemo-immunotherapy
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    sciencedirect.com/science/article/pii/S2666379126000765
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Selective inhibition of ALDH1A3 impedes breast cancer growth and metastasis by blocking ALDH1A3-driven transcriptional programs
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    pmc.ncbi.nlm.nih.gov/articles/PMC12962171/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The discovery and characterization of HBS-101, a novel inhibitor of midkine, as a therapeutic agent for the treatment of triple negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12353485/
  19. Feb 2026
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring the 89Zr/177Lu Theranostic Pairing with an Extracellular Matrix Targeted Radiopharmaceutical Against Triple Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12921459/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spermine Oxidase Serves as a Key Functional Node in Microbial Dysbiosis-Induced Breast Carcinogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12915686/
  22. www.sciencedirect.com www.sciencedirect.com
    RAD51 succinylation regulates homologous recombination and contributes to the chemosensitivity in cancer
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    sciencedirect.com/science/article/pii/S1097276526000626
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FAM135B Deficiency Inhibits Cytotoxic T-cell Activity in Triple-Negative Breast Cancer by Blocking the IFI16-Dependent STING Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12865359/
  24. Jan 2026
  25. www.nature.com www.nature.com
    CDK2 inhibitor BLU-222 synergizes with CDK4/6 inhibitors in drug resistant breast cancers through p21/p27 induction
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    nature.com/articles/s41467-025-67865-4
  26. link.springer.com link.springer.com
    Comparative theranostic efficacy of 177Lu- and 161Tb-labeled A1K2 SdAb in mesothelin-positive tumors
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    link.springer.com/article/10.1007/s00259-025-07723-z
  27. Dec 2025
  28. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer
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    sciencedirect.com:5037/science/article/pii/S2666379125005518
  29. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Exploration of precise classification and therapeutic targets of breast cancer based on genes related to neuro-cancer crosstalk
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    sciencedirect.com:5037/science/article/pii/S193652332500378X
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intrinsic RB activation induces tumoral and stromal anti-tumor responses that limit triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12669681/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZYS-1 is not an ADAR1 inhibitor
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    pmc.ncbi.nlm.nih.gov/articles/PMC12621589/
  32. Nov 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12530129/
  34. www.sciencedirect.com www.sciencedirect.com
    KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C
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    sciencedirect.com/science/article/pii/S2211124725012860
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined XPO1 Inhibition and Parthenolide Treatment Can Be Efficacious in Treating Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12564529/
  36. Oct 2025
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PARP inhibitor and PRMT5 inhibitor synergy is independent of BRCA1/2 and MTAP status in breast cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12540990/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12523003/
  39. Sep 2025
  40. www.sciencedirect.com www.sciencedirect.com
    HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413125003821
  41. Aug 2025
  42. www.biorxiv.org www.biorxiv.org
    Breast cancer cell migration is potentiated by associated fibroblasts through a laminin-511-Integrin α6β1-transduced Arp2/3 localization
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    biorxiv.org/content/10.1101/2025.08.10.669320v1
  43. 52.53.155.43 52.53.155.43
    2025.08.06.668996v1.full-html.html
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    52.53.155.43/9762f0542a12c1b879bb3817e6abf20525e5b06e/2025.08.06.668996v1.full-html.html
  44. www.biorxiv.org www.biorxiv.org
    ZYS-1 is not an ADAR1 inhibitor
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    biorxiv.org/content/10.1101/2025.08.08.669362v2
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
  46. Jul 2025
  47. www.sciencedirect.com www.sciencedirect.com
    Dual Regulation of FZD1/7 by IGF2BP3 Enhances Stem-like Properties and Carboplatin Resistance in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S0304383525005130
  48. pubs.acs.org pubs.acs.org
    Novel Aptamer-Drug Conjugate for Targeted Therapy in Triple-Negative Breast Cancer
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    pubs.acs.org/doi/full/10.1021/acs.jmedchem.5c00492
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Potent Inhibitor of Caspase-8 Based on the IL-18 Tetrapeptide Sequence Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases
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    pmc.ncbi.nlm.nih.gov/articles/PMC12371506/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Novel B7-H4xCD3 Bispecific T-cell Engager (PF-07260437) Synergizes with Breast Cancer Standard of Care and Immune Checkpoint Therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214883/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  52. Jun 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune targeting of triple-negative breast cancer through a clinically actionable STING agonist-CAR T cell platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281382/
  54. www.sciencedirect.com www.sciencedirect.com
    Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S2451945625001655
  55. May 2025
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TOP1 Mutations and Cross-Resistance to Antibody–Drug Conjugates in Patients with Metastatic Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079096/
  57. Apr 2025
  58. www.sciencedirect.com www.sciencedirect.com
    CD36-mediated endocytosis of proteolysis-targeting chimeras
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    sciencedirect.com/science/article/pii/S0092867425003861
  59. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/73f4a278983fd3a9b93fed6443158024ffc69ddc/PDF-html.html
  60. Feb 2025
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842356/
  62. aacrjournals.org aacrjournals.org
    Arginine methylation of DDX3 by PRMT1 mediates mitochondrial homeostasis to promote breast cancer metastasis
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    aacrjournals.org/cancerres/article/84/18/3023/747792/Arginine-Methylation-of-DDX3-by-PRMT1-Mediates
  63. www.sciencedirect.com www.sciencedirect.com
    Defining hypoxia in cancer: A landmark evaluation of hypoxia gene expression signatures
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    sciencedirect.com/science/article/pii/S2666979X25000205
  64. Jan 2025
  65. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/840490bae2d41c14c5baad0f632c2c699ffc05d9/PDF-html.html
  66. Dec 2024
  67. www.mdpi.com www.mdpi.com
    Discovery, Validation and Mechanistic Study of XPO1 Inhibition in the Treatment of Triple-Negative Breast Cancer
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    mdpi.com/2072-6694/16/23/3980
  68. www.sciencedirect.com www.sciencedirect.com
    Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates
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    sciencedirect.com/science/article/pii/S2451945624004586
  69. Nov 2024
  70. www.biorxiv.org www.biorxiv.org
    Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
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    biorxiv.org/content/10.1101/2024.11.07.622456v1
  71. www.sciencedirect.com www.sciencedirect.com
    A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells
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    sciencedirect.com/science/article/pii/S2451945624004434
  72. Sep 2024
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic effects of PARP inhibition and cholesterol biosynthesis pathway modulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11403291/
  74. www.sciencedirect.com www.sciencedirect.com
    Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124724011021
  75. Aug 2024
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAS3681, an androgen receptor antagonist, prevents drug resistance driven by aberrant androgen receptor signaling in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306513/
  77. www.embopress.org www.embopress.org
    Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies
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    embopress.org/doi/full/10.15252/emmm.202012716
  78. May 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063688/
  80. link.springer.com link.springer.com
    A novel long non-coding RNA MIR4500HG003 promotes tumor metastasis through miR-483-3p-MMP9 axis in triple-negative breast cancer
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    link.springer.com/article/10.1038/s41419-024-06675-w
  81. Apr 2024
  82. www.sciencedirect.com www.sciencedirect.com
    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    sciencedirect.com/science/article/pii/S2211124724004443
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993856/
  84. Mar 2024
  85. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  86. Feb 2024
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844833/
  88. Jan 2024
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
  90. www.sciencedirect.com www.sciencedirect.com
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    sciencedirect.com/science/article/pii/S1097276523010225
  91. Dec 2023
  92. www.sciencedirect.com www.sciencedirect.com
    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    sciencedirect.com/science/article/pii/S2666379123005438
  93. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
  94. Nov 2023
  95. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004223023684-main-html.html
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    52.53.155.43/971cabf0250f4b5e2a55288715a0710b0a0da054/1-s2.0-S2589004223023684-main-html.html
  96. www.sciencedirect.com www.sciencedirect.com
    Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins
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    sciencedirect.com/science/article/pii/S2666379123004329
  97. Oct 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM21 mediates the synergistic effect of Olaparib and Sorafenib by degrading BRCA1 through ubiquitination in TNBC
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    ncbi.nlm.nih.gov/pmc/articles/PMC10589312/
  99. www.mdpi.com www.mdpi.com
    ETHE1 Accelerates Triple-Negative Breast Cancer Metastasis by Activating GCN2/eIF2α/ATF4 Signaling
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    mdpi.com/1422-0067/24/19/14566
  100. dx.doi.org dx.doi.org
    Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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    dx.doi.org/10.1158/2767-9764.CRC-23-0236
  101. Jul 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10368911/
  103. Jun 2023
  104. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    nature.com/articles/s41467-023-39241-7
  105. Mar 2023
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug–gene Interaction Screens Coupled to Tumor Data Analyses Identify the Most Clinically Relevant Cancer Vulnerabilities Driving Sensitivity to PARP Inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC10035383/
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10002699/
  108. Nov 2022
  109. www.nature.com www.nature.com
    Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer
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    nature.com/articles/s41417-022-00559-x
  110. Oct 2022
  111. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
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    sciencedirect.com/science/article/pii/S1550413122004119
  112. Sep 2022
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decellularization of xenografted tumors provides cell-specific in vitro 3D environment
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    ncbi.nlm.nih.gov/pmc/articles/PMC9434107/
  114. Aug 2022
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytotoxicity and molecular-docking approach of a new rosane-type diterpenoid from the roots of Euphorbia nematocypha
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    ncbi.nlm.nih.gov/pmc/articles/PMC9393309/
  116. Jun 2022
  117. aacrjournals.org aacrjournals.org
    Rab13 sustains breast cancer stem cells by supporting tumor-stroma crosstalk
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    aacrjournals.org/cancerres/article/82/11/2124/699097/Rab13-Sustains-Breast-Cancer-Stem-Cells-by
  118. May 2022
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    8-azaadenosine and 8-chloroadenosine are not selective inhibitors of ADAR
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    ncbi.nlm.nih.gov/pmc/articles/PMC9113518/
  120. Mar 2022
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
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    ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
  122. www.sciencedirect.com www.sciencedirect.com
    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
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    sciencedirect.com/science/article/pii/S2211124722001759
  123. Feb 2022
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