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    Multi-omics analysis reveals the attenuation of the interferon pathway as a driver of chemo-refractory ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379125003891
  3. Aug 2025
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    Coordinated protein modules define DNA damage responses to carboplatin at single-cell resolution in human ovarian carcinoma models
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    sciencedirect.com/science/article/pii/S2666379125003684
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    Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer
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    biorxiv.org/content/10.1101/2025.08.10.669554v1
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Azenosertib Is a Potent and Selective WEE1 Kinase Inhibitor with Broad Antitumor Activity Across a Range of Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314526/
  7. Jul 2025
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    Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune Activation
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    Recapitulating physiologically relevant oxygen levels and extracellular matrix remodeling in patient-derived tumor-immune tunable models reveal targeting opportunities for immunologically cold high-grade serous tumors
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    biorxiv.org/content/10.1101/2025.06.23.661098v1
  10. Jun 2025
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  13. May 2025
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    Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11534535/
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  17. Apr 2025
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    Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification
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  20. Feb 2025
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    Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors
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  22. Jan 2025
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    Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers
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  24. Nov 2024
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    Solid tumor immunotherapy using NKG2D-based adaptor CAR T cells
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    Multicompartmentalized Microvascularized Tumor-on-a-Chip to Study Tumor-Stroma Interactions and Drug Resistance in Ovarian Cancer
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  27. Aug 2024
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    The Microenvironment of Solid Tumors: Components and Current Challenges of Tumor-on-a-Chip Models
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    liebertpub.com/doi/10.1089/ten.teb.2024.0088
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    Novel chromobox 2 inhibitory peptide decreases tumor progression
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  30. Jun 2024
  31. www.cell.com www.cell.com
    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
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    Multicompartmentalized microvascularized tumor-on-a-chip to study tumor-stroma interactions and drug resistance in ovarian cancer
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    biorxiv.org/content/10.1101/2024.05.29.596456v1
  33. Apr 2024
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    VDX-111, a novel small molecule, induces necroptosis to inhibit ovarian cancer progression
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  35. Feb 2024
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    A revised molecular model of ovarian cancer biomarker CA125 (MUC16) enabled by long-read sequencing
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  38. Oct 2023
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    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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  40. Sep 2023
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    RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells
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    dx.doi.org/10.1093/nar/gkad733
  42. Jul 2023
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    Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis
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  44. Jun 2023
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    Novel chromobox 2 inhibitory peptide decreases tumor progression
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  46. Apr 2023
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    Actionable spontaneous antibody responses antagonize malignant progression in ovarian carcinoma
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    sciencedirect.com/science/article/pii/S0090825823001671
  48. Feb 2023
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting DUSP activity as a treatment for high grade serous ovarian carcinoma
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357105/
  51. Aug 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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  53. Jul 2022
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  55. Jun 2022
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    The SETDB1–TRIM28 complex suppresses antitumor immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC8647838/
  58. Apr 2022
  59. aacrjournals.org aacrjournals.org
    Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models
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    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    sciencedirect.com/science/article/pii/S2211124722003886
  61. Jan 2022
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    Sequential azacitidine and carboplatin induces immune activation in platinum-resistant high-grade serous ovarian cancer cell lines and primes for checkpoint inhibitor immunotherapy
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    link.springer.com/article/10.1186/s12885-022-09197-w
  63. Sep 2021
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    High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment
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  65. Aug 2021
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  67. Oct 2020
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    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
  69. Sep 2020
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC6929979/
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    Metabolism of Estrogens: Turnover Differs Between Platinum-Sensitive and -Resistant High-Grade Serous Ovarian Cancer Cells
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    mdpi.com/2072-6694/12/2/279
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    The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells
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    sciencedirect.com/science/article/pii/S1535610820300428
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    A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets
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  74. Jan 2020
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    Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles
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