Hypothesis

12 Matching Annotations

Aug 2025
www.sciencedirect.com www.sciencedirect.com

A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers

1
1. scibot 08 Aug 2025
  
  in Public
  
  RRID:CVCL_1382
  
  DOI: 10.1016/j.ccell.2025.07.006
  
  Resource: (KCLB Cat# 22158, RRID:CVCL_1382)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1382
  
  What is this?
  
  RRID:CVCL_1382
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RRID:CVCL_1382

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825003101
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Overcoming multidrug resistance in gastrointestinal cancers with a CDH17-targeted ADC conjugated to a DNA topoisomerase inhibitor

1
1. scibot 02 Jul 2025
  
  in Public
  
  CVCL_1382
  
  DOI: 10.1016/j.xcrm.2025.102213
  
  Resource: (KCLB Cat# 22158, RRID:CVCL_1382)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1382
  
  What is this?
  
  RRID:CVCL_1382
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RRID:CVCL_1382

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scibot

URL

sciencedirect.com/science/article/pii/S2666379125002861
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TR-107, An Agonist of Caseinolytic Peptidase Proteolytic Subunit, Disrupts Mitochondrial Metabolism and Inhibits the Growth of Human Colorectal Cancer Cells

1
1. scibot 11 Jun 2025
  
  in Public
  
  RRID:CVCL_1382
  
  DOI: 10.1158/1535-7163.MCT-24-0170
  
  Resource: (KCLB Cat# 22158, RRID:CVCL_1382)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1382
  
  What is this?
  
  RRID:CVCL_1382
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RRID:CVCL_1382

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11614700/
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases

1
1. scibot 26 Apr 2024
  
  in Public
  
  CVCL_1382
  
  DOI: 10.1016/j.xcrm.2024.101523
  
  Resource: (KCLB Cat# 22158, RRID:CVCL_1382)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1382
  
  What is this?
  
  RRID:CVCL_1382
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RRID:CVCL_1382

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scibot

URL

sciencedirect.com/science/article/pii/S2666379124001927
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells

1
1. scibot 19 Jan 2024
  
  in Public
  
  RRID:CVCL_1382
  
  DOI: 10.1016/j.xcrm.2023.101376
  
  Resource: (KCLB Cat# 22158, RRID:CVCL_1382)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1382
  
  What is this?
  
  RRID:CVCL_1382
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RRID:CVCL_1382

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scibot

URL

sciencedirect.com/science/article/pii/S2666379123006055
May 2023
www.sciencedirect.com www.sciencedirect.com

KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

1
1. scibot 05 May 2023
  
  in Public
  
  RRID:CVCL_1382
  
  DOI: 10.1016/j.celrep.2022.111077
  
  Resource: (KCLB Cat# 22158, RRID:CVCL_1382)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1382
  
  What is this?
  
  RRID:CVCL_1382
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RRID:CVCL_1382

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722008750
Dec 2021
www.sciencedirect.com www.sciencedirect.com

Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach

1
1. scibot 15 Dec 2021
  
  in Public
  
  CRL-2158
  
  DOI: 10.1016/j.celrep.2021.110096
  
  Resource: (KCLB Cat# 22158, RRID:CVCL_1382)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1382
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1382
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RRIDCUR:Missing

RRID:CVCL_1382

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721015904
Jan 2021
jeccr.biomedcentral.com jeccr.biomedcentral.com

Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer

1
1. scibot 12 Jan 2021
  
  in Public
  
  CVCL_1382
  
  DOI: 10.1186/s13046-020-01811-8
  
  Resource: (KCLB Cat# 22158, RRID:CVCL_1382)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1382
  
  What is this?
  
  RRID:CVCL_1382 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1382

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scibot

URL

jeccr.biomedcentral.com/articles/10.1186/s13046-020-01811-8
Aug 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Novel engineered TRAIL‐based chimeric protein strongly inhibits tumor growth and bypasses TRAIL resistance

1
1. scibot 17 Aug 2020
  
  in Public
  
  RRID:CVCL_1382
  
  DOI: 10.1002/ijc.32845
  
  Resource: (KCLB Cat# 22158, RRID:CVCL_1382)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1382
  
  Curator comments: LS1034 cell line ATCC Cat# CRL-2158
  
  What is this?
  
  RRID:CVCL_1382
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RRID:CVCL_1382

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.32845
Nov 2018
www.frontiersin.org www.frontiersin.org

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1382
  
  Resource used:
  
  (ATCC Cat# CRL-2158, RRID:CVCL_1382)
  
  SciCrunch record: RRID:CVCL_1382
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1382
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RRID:CVCL_1382

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scibot

URL

frontiersin.org/article/10.3389/fphys.2018.00911/full
www.sciencedirect.com www.sciencedirect.com

Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-2158
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-2158, RRID:CVCL_1382)
  
  SciCrunch record: RRID:CVCL_1382
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1382 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1382

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scibot

URL

sciencedirect.com/science/article/pii/S153561081830309X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1382
  
  Resource used:
  
  (ATCC Cat# CRL-2158, RRID:CVCL_1382)
  
  SciCrunch record: RRID:CVCL_1382
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1382
Visit annotations in context

Tags

RRID:CVCL_1382

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6064950/