21 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    ADT-030, a novel PDE10 inhibitor, demonstrates potent antitumor activity in pancreatic ductal adenocarcinoma
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    biorxiv.org/content/10.64898/2026.02.11.705411v1
  3. Dec 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sustained reductions in valine and isoleucine mediate anti-cancer pharmacological effects of inhibiting amino acid transporter LAT1 in cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12673697/
  5. Sep 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875992/
  7. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    An LCN2-Dependent Positive-Feedback Loop Between Gastric Cancer Cells and Tumor-Associated-Macrophages Mediates Lymphangiogenesis and Lymphatic Metastasis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202508352
  8. May 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glecirasib, a Potent and Selective Covalent KRAS G12C Inhibitor Exhibiting Synergism with Cetuximab or SHP2 Inhibitor JAB-3312
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    pmc.ncbi.nlm.nih.gov/articles/PMC12076188/
  10. Apr 2025
  11. www.sciencedirect.com www.sciencedirect.com
    CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers
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    sciencedirect.com/science/article/pii/S2451945625000960
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962398/
  13. Mar 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De novo identification of universal cell mechanics gene signatures
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    pmc.ncbi.nlm.nih.gov/articles/PMC11832173/
  15. Aug 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Predictive biomarkers for metachronous gastric cancer development after endoscopic resection of early gastric cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11339598/
  17. May 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CBF-beta mitigates PI3K-alpha-specific inhibitor killing through PIM1 in PIK3CA mutant gastric cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811747/
  19. Mar 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905675/
  21. Feb 2024
  22. 52.53.155.43 52.53.155.43
    cd-23-0954-html.html
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    52.53.155.43/aaf525c30ae01b53e260240fad732783dfb4bbac/cd-23-0954-html.html
  23. Jan 2024
  24. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Therapeutic antibody targeting natriuretic peptide receptor 1 inhibits gastric cancer growth via BCL-2-mediated intrinsic apoptosis
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34831
  25. Jul 2022
  26. www.medrxiv.org www.medrxiv.org
    Transcriptomic Profiling on Localized Gastric Cancer Identified CPLX1 as a Gene Promoting Malignant Phenotype of Gastric Cancer and a Predictor of Recurrence after Surgery and Subsequent Chemotherapy
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    medrxiv.org/content/10.1101/2021.03.25.21254204v1
  27. Jun 2022
  28. link.springer.com link.springer.com
    Transcriptomic profiling on localized gastric cancer identified CPLX1 as a gene promoting malignant phenotype of gastric cancer and a predictor of recurrence after surgery and subsequent chemotherapy
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    link.springer.com/article/10.1007/s00535-022-01884-6
  29. Mar 2022
  30. link.springer.com link.springer.com
    Lysosomal-associated membrane protein family member 5 promotes the metastatic potential of gastric cancer cells
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    link.springer.com/article/10.1007/s10120-022-01284-y
  31. Oct 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Kinase DYRK2 acts as a regulator of autophagy and an indicator of favorable prognosis in gastric carcinoma
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    sciencedirect.com/science/article/pii/S0927776521006263
  33. Jun 2021
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer
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    onlinelibrary.wiley.com/doi/10.1002/ctm2.454
  35. May 2021
  36. www.sciencedirect.com www.sciencedirect.com
    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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    sciencedirect.com/science/article/pii/S1074761320302715
  37. Sep 2020
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ONECUT2 upregulation is associated with CpG hypomethylation at promoter‐proximal DNA in gastric cancer and triggers ACSL5
    1
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32946