Hypothesis

23 Matching Annotations

Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer

1
1. scibot 08 Oct 2025
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1158/1535-7163.MCT-24-0861
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12493205/
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancer

1
1. scibot 27 Aug 2025
  
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  RRID:CVCL_1453
  
  DOI: 10.1016/j.devcel.2025.07.023
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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sciencedirect.com/science/article/pii/S153458072500499X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Azenosertib Is a Potent and Selective WEE1 Kinase Inhibitor with Broad Antitumor Activity Across a Range of Solid Tumors

1
1. scibot 05 Aug 2025
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1158/1535-7163.MCT-24-1194
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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pmc.ncbi.nlm.nih.gov/articles/PMC12314526/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Roles of Annexin A1 Expression in Small Cell Lung Cancer

1
1. scibot 21 May 2025
  
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  RRID:CVCL_1453
  
  DOI: 10.3390/cancers17091407
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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pmc.ncbi.nlm.nih.gov/articles/PMC12070913/
Apr 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 19 Apr 2025
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1158/1535-7163.mct-24-1194
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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52.53.155.43/fb744ae1c201e64705cbba4fb67640ca74ff97a4/PDF-html.html
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung Cancer

1
1. scibot 15 Feb 2025
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.3390/ijms26031293
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11818609/
52.53.155.43 52.53.155.43

1-s2.0-S2589004225002032-main-html.html

1
1. scibot 04 Feb 2025
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1016/j.isci.2025.111943
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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52.53.155.43/e4b607a49cf0f3ebbe47c0ce3ad109363070bc8e/1-s2.0-S2589004225002032-main-html.html
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Noncanonical inhibition of topoisomerase II alpha by oxidative stress metabolites

1
1. scibot 30 Jan 2025
  
  in Public
  
  ATCC Cat #CRL-5853
  
  DOI: 10.1016/j.redox.2025.103504
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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sciencedirect.com/science/article/pii/S2213231725000175
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Efficacy of CBP/p300 Dual Inhibitors against De-repression of KREMEN2 in cBAF-Deficient Cancers

1
1. scibot 08 Jan 2025
  
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  RRID:CVCL_1453
  
  DOI: 10.1158/2767-9764.CRC-24-0484
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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pmc.ncbi.nlm.nih.gov/articles/PMC11701801/
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Lurbinectedin sensitizes PD-L1 blockade therapy by activating STING-IFN signaling in small-cell lung cancer

1
1. scibot 10 Dec 2024
  
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  RRID:CVCL_1453
  
  DOI: 10.1016/j.xcrm.2024.101852
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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sciencedirect.com/science/article/pii/S2666379124006232
genomebiology.biomedcentral.com genomebiology.biomedcentral.com

Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors

1
1. scibot 05 Dec 2024
  
  in Public
  
  RRID: CVCL_1453
  
  DOI: 10.1186/s13059-024-03438-w
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @AlecAsdourian
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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genomebiology.biomedcentral.com/articles/10.1186/s13059-024-03438-w
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies

1
1. scibot 25 Jul 2024
  
  in Public
  
  RRID: CVCL_1453
  
  DOI: 10.1016/j.ccell.2024.06.006
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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sciencedirect.com/science/article/pii/S1535610824002319
www.sciencedirect.com www.sciencedirect.com

Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

1
1. scibot 25 Jul 2024
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1016/j.ccell.2024.06.012
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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sciencedirect.com/science/article/pii/S153561082400237X
May 2024
aacrjournals.org aacrjournals.org

Molecular and pathological characterization of YAP1-expressing small cell lung cancer cell lines leads to reclassification as SMARCA4-deficient malignancies

1
1. scibot 03 May 2024
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1158/1078-0432.CCR-23-2360
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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aacrjournals.org/clincancerres/article/30/9/1846/743134/Molecular-and-Pathologic-Characterization-of-YAP1
Mar 2024
www.sciencedirect.com www.sciencedirect.com

CDK-independent role of D-type cyclins in regulating DNA mismatch repair

2
1. scibot 08 Mar 2024
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1016/j.molcel.2024.02.010
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
2. scibot 08 Mar 2024
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1016/j.molcel.2024.02.010
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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sciencedirect.com/science/article/pii/S1097276524001291
Feb 2024
52.53.155.43 52.53.155.43

d1-html.html

1
1. scibot 29 Feb 2024
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1158/1078-0432.ccr-23-2360
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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52.53.155.43/9d9c84a50a37d03d2f105a9516b773f31c793012/d1-html.html
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Replication stress defines distinct molecular subtypes across cancers

1
1. scibot 19 Nov 2022
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1158/2767-9764.crc-22-0168
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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ncbi.nlm.nih.gov/pmc/articles/PMC9648410/
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer

1
1. scibot 22 Aug 2022
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1016/j.cels.2022.07.006
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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sciencedirect.com/science/article/pii/S2405471222003131
May 2022
www.sciencedirect.com www.sciencedirect.com

WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

1
1. scibot 19 May 2022
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1016/j.celrep.2022.110814
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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sciencedirect.com/science/article/pii/S221112472200585X
Jan 2022
www.sciencedirect.com www.sciencedirect.com

SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia

1
1. scibot 12 Jan 2022
  
  in Public
  
  CRL-5853
  
  DOI: 10.1016/j.celrep.2021.110233
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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sciencedirect.com/science/article/pii/S2211124721017423
Nov 2021
www.nature.com www.nature.com

Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer

1
1. scibot 21 Nov 2021
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1038/s41467-021-26823-6
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453
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nature.com/articles/s41467-021-26823-6
Aug 2021
www.sciencedirect.com www.sciencedirect.com

RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_1453
  
  DOI: 10.1016/j.chembiol.2019.12.005
  
  Resource: (ATCC Cat# CRL-5853, RRID:CVCL_1453)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1453
  
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  RRID:CVCL_1453 RRIDCUR:Validated
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RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S2451945619304015