Hypothesis

12 Matching Annotations

Oct 2024
aacrjournals.org aacrjournals.org

ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK

1
1. scibot 02 Oct 2024
  
  in Public
  
  RRID: CVCL_1464
  
  DOI: 10.1158/1535-7163.MCT-20-0909
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:CVCL_1464
  
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  RRID:CVCL_1464
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RRID:CVCL_1464

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scibot

URL

aacrjournals.org/mct/article/20/10/1757/665735/ASTX029-a-Novel-Dual-mechanism-ERK-Inhibitor
May 2024
aacrjournals.org aacrjournals.org

TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity

2
1. scibot 23 May 2024
  
  in Public
  
  RRID:CVCL_1464
  
  DOI: 10.1158/2159-8290.CD-23-0700
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1464
  
  What is this?
  
  RRID:CVCL_1464
2. scibot 23 May 2024
  
  in Public
  
  RRID:CVCL_1464
  
  DOI: 10.1158/2159-8290.CD-23-0700
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1464
  
  What is this?
  
  RRID:CVCL_1464
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RRID:CVCL_1464

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scibot

URL

aacrjournals.org/cancerdiscovery/article/14/5/752/745044/TREX1-Inactivation-Unleashes-Cancer-Cell-STING
www.sciencedirect.com www.sciencedirect.com

Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations

1
1. scibot 23 May 2024
  
  in Public
  
  RRID:CVCL_1464
  
  DOI: 10.1016/j.xcrm.2024.101578
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1464
  
  What is this?
  
  RRID:CVCL_1464
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RRID:CVCL_1464

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scibot

URL

sciencedirect.com/science/article/pii/S2666379124002702
Oct 2022
www.nature.com www.nature.com

A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo

1
1. scibot 11 Oct 2022
  
  in Public
  
  RRID:CVCL_1464
  
  DOI: 10.1038/s41467-022-33430-6
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1464
  
  What is this?
  
  RRID:CVCL_1464
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RRID:CVCL_1464

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scibot

URL

nature.com/articles/s41467-022-33430-6
Sep 2022
www.sciencedirect.com www.sciencedirect.com

MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer

1
1. scibot 24 Sep 2022
  
  in Public
  
  CRL-5865
  
  DOI: 10.1016/j.ccell.2022.08.015
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:CVCL_1464
  
  What is this?
  
  RRID:CVCL_1464
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RRID:CVCL_1464

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scibot

URL

sciencedirect.com/science/article/pii/S1535610822003798
Aug 2021
www.sciencedirect.com www.sciencedirect.com

RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_1464
  
  DOI: 10.1016/j.chembiol.2019.12.005
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1464
  
  What is this?
  
  RRID:CVCL_1464 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1464

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scibot

URL

sciencedirect.com/science/article/pii/S2451945619304015
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma

1
1. scibot 30 Jul 2021
  
  in Public
  
  H1355
  
  DOI: 10.1016/j.ccell.2019.07.002
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1464
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1464
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RRIDCUR:Missing

RRID:CVCL_1464

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819303290
www.sciencedirect.com www.sciencedirect.com

Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy

1
1. scibot 29 Jul 2021
  
  in Public
  
  H1355
  
  DOI: 10.1016/j.ccell.2019.06.008
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1464
  
  What is this?
  
  RRID:CVCL_1464 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1464

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819302995
Sep 2020
www.sciencedirect.com www.sciencedirect.com

A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers

1
1. scibot 09 Sep 2020
  
  in Public
  
  RRID:CVCL_1464
  
  DOI: 10.1016/j.ccell.2020.03.004
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1464
  
  What is this?
  
  RRID:CVCL_1464 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1464

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scibot

URL

sciencedirect.com/science/article/pii/S1535610820301057
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids

1
1. scibot 13 Jan 2020
  
  in Public
  
  CVCL_1464
  
  DOI: 10.1016/j.cmet.2019.11.012
  
  Resource: (KCLB Cat# 91355, RRID:CVCL_1464)
  
  Curator: @ethanbadger
  
  SciCrunch record: CVCL_1464
  
  What is this?
  
  RRID:CVCL_1464 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1464

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scibot

URL

sciencedirect.com/science/article/pii/S1550413119306199
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-5865
  
  Curator: @Jmenke
  
  Resource used:
  
  (KCLB Cat# 91355, RRID:CVCL_1464)
  
  SciCrunch record: RRID:CVCL_1464
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1464 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:CVCL_1464

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610818303696