Hypothesis

21 Matching Annotations

May 2026
www.biorxiv.org www.biorxiv.org

Acquired resistance to the PRMT5 inhibitor confers collateral sensitivity to MEK inhibition in MTAP-null non-small cell lung cancer

1
1. scibot 01 May 2026
  
  in Public
  
  RRID:CVCL_1472
  
  DOI: 10.64898/2026.04.16.719008
  
  Resource: (RRID:CVCL_1472)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1472
  
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  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

biorxiv.org/content/10.64898/2026.04.16.719008v1
May 2025
link.springer.com link.springer.com

NECTIN4 regulates the cell surface expression of CD155 in non-small cell lung cancer cells and induces tumor resistance to PD-1 inhibitors

1
1. scibot 23 May 2025
  
  in Public
  
  RRID: CVCL_1472
  
  DOI: 10.1007/s00262-025-04079-z
  
  Resource: (RRID:CVCL_1472)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:CVCL_1472
  
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  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

link.springer.com/article/10.1007/s00262-025-04079-z
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma

1
1. scibot 29 Mar 2025
  
  in Public
  
  RRID:CVCL_1472
  
  DOI: 10.1016/j.molcel.2025.03.001
  
  Resource: (RRID:CVCL_1472)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

sciencedirect.com/science/article/pii/S1097276525001947
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting AKR1B10 by drug repurposing with epalrestat overcomes chemoresistance in non-small cell lung cancer patient-derived tumor organoids

1
1. scibot 05 Sep 2024
  
  in Public
  
  RRID: CVCL_1472
  
  DOI: 10.1158/1078-0432.CCR-23-3980
  
  Resource: (RRID:CVCL_1472)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_1472
  
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  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11369614/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma

1
1. scibot 27 Jul 2024
  
  in Public
  
  RRID:CVCL_1472
  
  DOI: 10.1158/2767-9764.CRC-23-0428
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1472
  
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  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11270646/
May 2024
www.sciencedirect.com www.sciencedirect.com

Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers

1
1. scibot 17 May 2024
  
  in Public
  
  CRL-5872
  
  DOI: 10.1016/j.molcel.2024.04.009
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1472
  
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  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

sciencedirect.com/science/article/pii/S1097276524003241
Apr 2024
www.sciencedirect.com www.sciencedirect.com

NECTIN2 is a prognostic biomarker and potential therapeutic target in lung adenocarcinoma

1
1. scibot 30 Apr 2024
  
  in Public
  
  H1437
  
  DOI: 10.1016/j.resinv.2024.04.002
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1472
  
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  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

sciencedirect.com/science/article/pii/S2212534524000558
www.sciencedirect.com www.sciencedirect.com

A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8

1
1. scibot 09 Apr 2024
  
  in Public
  
  RRID:CVCL_1472
  
  DOI: 10.1016/j.gene.2024.148449
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

sciencedirect.com/science/article/pii/S0378111924003305
Jan 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling

1
1. scibot 25 Jan 2024
  
  in Public
  
  RRID:CVCL_1472
  
  DOI: 10.1002/1878-0261.13554
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
Nov 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment

1
1. scibot 12 Nov 2023
  
  in Public
  
  RRID: CVCL_1472
  
  DOI: 10.1002/ijc.34783
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.34783
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Individualized tumor-informed circulating tumor DNA analysis for postoperative monitoring of non-small cell lung cancer

1
1. scibot 06 Oct 2023
  
  in Public
  
  RRID: CVCL_1472
  
  DOI: 10.1016/j.ccell.2023.08.010
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

sciencedirect.com/science/article/pii/S1535610823002866
May 2023
52.53.155.43 52.53.155.43

CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation

1
1. scibot 25 May 2023
  
  in Public
  
  RRID:CVCL_1472
  
  DOI: 10.1002/1878-0261.13438
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

52.53.155.43/66fe689ddea2ba9b3d8dd8042f1d3395e9a7b944/Molecular Oncology - 2023 - Quandt - CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and-html.html
Aug 2021
www.sciencedirect.com www.sciencedirect.com

RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_1472
  
  DOI: 10.1016/j.chembiol.2019.12.005
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1472
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RRID:CVCL_1472

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2451945619304015
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy

1
1. scibot 29 Jul 2021
  
  in Public
  
  H1437
  
  DOI: 10.1016/j.ccell.2019.06.008
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1472

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819302995
www.sciencedirect.com www.sciencedirect.com

Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

1
1. scibot 29 Jul 2021
  
  in Public
  
  Human: H1437
  
  DOI: 10.1016/j.cmet.2019.06.014
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1472

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413119303171
May 2021
www.sciencedirect.com www.sciencedirect.com

3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:CVCL_1472
  
  DOI: 10.1016/j.molcel.2020.10.010
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

sciencedirect.com/science/article/pii/S1097276520306936
Sep 2020
www.sciencedirect.com www.sciencedirect.com

KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

1
1. scibot 04 Sep 2020
  
  in Public
  
  Human: NCI-H1437
  
  DOI: 10.1016/j.ccell.2020.03.005
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1472

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820301069
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
1. scibot 13 Jan 2020
  
  in Public
  
  CVCL_1472
  
  DOI: 10.1016/j.cmet.2019.01.020
  
  Resource: (KCLB Cat# 91437, RRID:CVCL_1472)
  
  Curator: @ethanbadger
  
  SciCrunch record: CVCL_1472
  
  What is this?
  
  RRID:CVCL_1472 RRIDCUR:Validated
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RRID:CVCL_1472

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413119300208
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target

1
1. scibot 05 Nov 2018
  
  in Public
  
  NCI-H1437
  
  Curator: @anp055
  
  Resource used:
  
  (KCLB Cat# 91437, RRID:CVCL_1472)
  
  SciCrunch record: RRID:CVCL_1472
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1472 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1472

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC3566312/
www.sciencedirect.com www.sciencedirect.com

Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1472
  
  Curator: @Jmenke
  
  Resource used:
  
  (KCLB Cat# 91437, RRID:CVCL_1472)
  
  SciCrunch record: RRID:CVCL_1472
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1472 RRIDCUR:Validated
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RRID:CVCL_1472

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S009286741831033X
onlinelibrary.wiley.com onlinelibrary.wiley.com

LOSS OF RUNX1 IS ASSOCIATED WITH AGGRESSIVE LUNG ADENOCARCINOMAS

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1472
  
  Resource used:
  
  (KCLB Cat# 91437, RRID:CVCL_1472)
  
  SciCrunch record: RRID:CVCL_1472
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1472
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RRID:CVCL_1472

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/jcp.26201/full