26 Matching Annotations
  1. Last 7 days
  2. www.pnas.org www.pnas.org
    Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer
    1
    1. scibot 25 Apr 2024
      RRID:CVCL_1495

      DOI: 10.1073/pnas.2319429121

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @scibot

      SciCrunch record: RRID:CVCL_1495

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    pnas.org/doi/abs/10.1073/pnas.2319429121
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
    1
    1. scibot 29 Mar 2024
      Cat#CRL-5895

      DOI: 10.1016/j.chembiol.2024.02.013

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @abever99

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S2451945624000874
  5. Jan 2024
  6. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling
    1
    1. scibot 25 Jan 2024
      RRID:CVCL_1495

      DOI: 10.1002/1878-0261.13554

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @anisehay

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
  7. Nov 2023
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
    1
    1. scibot 12 Nov 2023
      RRID:CVCL_1495

      DOI: 10.1002/ijc.34783

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @scibot

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34783
  9. Jul 2023
  10. www.nature.com www.nature.com
    MLK4 promotes glucose metabolism in lung adenocarcinoma through CREB-mediated activation of phosphoenolpyruvate carboxykinase and is regulated by KLF5
    1
    1. scibot 06 Jul 2023
      RRID: CVCL_1495

      DOI: 10.1038/s41389-023-00478-y

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @anisehay

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    nature.com/articles/s41389-023-00478-y
  11. May 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
    1
    1. scibot 04 May 2023
      RRID:CVCL_1495

      DOI: 10.1158/0008-5472.CAN-22-3000

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @scibot

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  13. Apr 2023
  14. www.mdpi.com www.mdpi.com
    TEAD Inhibitors Sensitize KRASG12C Inhibitors via Dual Cell Cycle Arrest in KRASG12C-Mutant NSCLC
    1
    1. scibot 20 Apr 2023
      RRID:CVCL_1495

      DOI: 10.3390/ph16040553

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @scibot

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    mdpi.com/1424-8247/16/4/553
  15. www.sciencedirect.com www.sciencedirect.com
    Cell-to-cell variability in Myc dynamics drives transcriptional heterogeneity in cancer cells
    1
    1. scibot 15 Apr 2023
      RRID:CVCL_1495

      DOI: 10.1016/j.celrep.2023.112401

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @scibot

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S2211124723004126
  16. Sep 2022
  17. www.sciencedirect.com www.sciencedirect.com
    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer
    1
    1. scibot 24 Sep 2022
      CRL-5895

      DOI: 10.1016/j.ccell.2022.08.015

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @a5munoz

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S1535610822003798
  18. Jan 2022
  19. www.sciencedirect.com www.sciencedirect.com
    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
    1
    1. scibot 26 Jan 2022
      RRID:CVCL_1495

      DOI: 10.1016/j.ccell.2021.12.009

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @scibot

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S1535610821006620
  20. Nov 2021
  21. www.sciencedirect.com www.sciencedirect.com
    FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma
    1
    1. scibot 03 Nov 2021
      CRL-5895

      DOI: 10.1016/j.celrep.2021.109905

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_1495

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      RRIDCUR:Missing RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S2211124721013759
  22. Aug 2021
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
    1
    1. scibot 11 Aug 2021
      ATCCCRL-5895

      DOI: 10.7554/eLife.66524

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @evieth

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    ncbi.nlm.nih.gov/pmc/articles/PMC8337080/
  24. www.sciencedirect.com www.sciencedirect.com
    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
    1
    1. scibot 01 Aug 2021
      RRID:CVCL_1495

      DOI: 10.1016/j.chembiol.2019.12.005

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_1495

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      RRIDCUR:Validated RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S2451945619304015
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer
    1
    1. scibot 01 Aug 2021
      RRID:CVCL_1495

      DOI: 10.7554/eLife.45572

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @evieth

      SciCrunch record: RRID:CVCL_1495

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      RRIDCUR:Validated RRID:CVCL_1495
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    ncbi.nlm.nih.gov/pmc/articles/PMC6584702/
  26. Jul 2021
  27. www.sciencedirect.com www.sciencedirect.com
    Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma
    1
    1. scibot 30 Jul 2021
      H1792

      DOI: 10.1016/j.ccell.2019.07.002

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_1495

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      RRIDCUR:Missing RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S1535610819303290
  28. www.sciencedirect.com www.sciencedirect.com
    Pharmaco-transcriptomic correlation analysis reveals novel responsive signatures to HDAC inhibitors and identifies Dasatinib as a synergistic interactor in small-cell lung cancer
    1
    1. scibot 09 Jul 2021
      RRID:CVCL_1495

      DOI: 10.1016/j.ebiom.2021.103457

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @scibot

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S2352396421002504
  29. May 2021
  30. www.sciencedirect.com www.sciencedirect.com
    3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis
    1
    1. scibot 07 May 2021
      CVCL_1495

      DOI: 10.1016/j.molcel.2020.10.010

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @scibot

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S1097276520306936
  31. Apr 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis
    1
    1. scibot 30 Apr 2021
      RRID:CVCL_1495

      DOI: 10.1016/j.cmet.2020.12.007

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @scibot

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S1550413120306628
  33. Sep 2020
  34. www.sciencedirect.com www.sciencedirect.com
    A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers
    1
    1. scibot 11 Sep 2020
      RRID:CVCL_1495

      DOI: 10.1016/j.ccell.2020.03.004

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_1495

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      RRIDCUR:Validated RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S1535610820301057
  35. www.sciencedirect.com www.sciencedirect.com
    KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer
    1
    1. scibot 04 Sep 2020
      Human: NCI-H1792

      DOI: 10.1016/j.ccell.2020.03.005

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610820301069
  36. Jan 2020
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Radioresistance of KRAS/TP53‐Mutated Lung Cancer can be overcome by Radiation Dose Escalation or EGFR Tyrosine Kinase Inhibition In Vivo
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_1495

      DOI: 10.1002/ijc.32598

      Resource: (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_1495

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      RRID:CVCL_1495 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32598
  38. Nov 2018
  39. www.sciencedirect.com www.sciencedirect.com
    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS
    1
    1. scibot 05 Nov 2018
      CRL-5895

      Curator: @Jmenke

      Resource used:

      (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      SciCrunch record: RRID:CVCL_1495

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_1495 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610818303696
  40. www.sciencedirect.com www.sciencedirect.com
    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_1495

      Curator: @Jmenke

      Resource used:

      (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      SciCrunch record: RRID:CVCL_1495

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_1495 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S009286741831033X
  41. www.sciencedirect.com www.sciencedirect.com
    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
    1
    1. scibot 05 Nov 2018
      CRL-5895

      Curator: @Jmenke

      Resource used:

      (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      SciCrunch record: RRID:CVCL_1495

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_1495 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867418300412
  42. www.sciencedirect.com www.sciencedirect.com
    Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_1495

      Resource used:

      (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      SciCrunch record: RRID:CVCL_1495

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_1495
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    sciencedirect.com/science/article/pii/S1535610818301831
  43. Nov 2017
  44. www.sciencedirect.com www.sciencedirect.com
    Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer
    1
    1. scibot 08 Nov 2017
      CRL-5895

      Curator: @Jmenke

      Resource used:

      (ATCC Cat# CRL-5895, RRID:CVCL_1495)

      SciCrunch record: RRID:CVCL_1495

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_1495 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867417310474