225 Matching Annotations
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    KRAS-mediated CCDC6 degradation drives xCT upregulation and ferroptosis evasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13369686/
  3. Jul 2026
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    Pemetrexed potentiates γδ T cell-based immunotherapy in NSCLC through ATM-STING-NF-κB-mediated induction of NKG2D ligands
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    sciencedirect.com/science/article/pii/S1567576926009616
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    Repurposed ethoxzolamide reprograms antitumor immunity through β-TrCP-dependent PD-L1 ubiquitination
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    sciencedirect.com/science/article/pii/S266637912600337X
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    Extracellular vesicles derived from cancer-associated fibroblasts facilitate NSCLC progression and metastasis via miR-664b-5p-mediated activation of the CXCL12/CXCR4 chemokine pathway
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    sciencedirect.com/science/article/pii/S0925443926002231
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    MTFR2 promotes VDAC1 oligomerization to reprogram BCAA metabolism in tumor cells to polarize TAMs in LUAD
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    Unbiased avidity-based isolation of antigen-specific T cells
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    Mitochondrial translocation of MDM2 and TFAM reprograms metabolism in treatment-refractory cancers
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  10. Jun 2026
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    Establishment of a Flow Cytometry Protocol for Binarily Detecting Circulating Tumor Cells with EGFR Mutation
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    Targeting TROP2 in drug-tolerant persister cells delays EGFR tyrosine kinase inhibitor resistance in non-small-cell lung cancer
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    The activity of EGFR CAR-NK and CAR-T cells against EGFR inhibitor-resistant NSCLC and drug-tolerant persister cells
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    aacrjournals.org/clincancerres/article/31/22/4745/767041/The-Activity-of-EGFR-CAR-NK-and-CAR-T-Cells
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    Effect of isoginkgetin on targeting methylenetetrahydrofolate dehydrogenase 2 to induce ROS-mediated apoptosis in non-small cell lung cancer
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    Hypoxia-activated PROTAC for dual inhibition of FAK and EGFR enables synergistic mechano-chemical cancer therapy
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    Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions
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    Acquired resistance to the PRMT5 inhibitor confers collateral sensitivity to MEK inhibition in MTAP-null non-small cell lung cancer
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  18. May 2026
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    Gasdermin C reprograms metabolism through the CAMKK2-AMPK axis to promote lung adenocarcinoma progression and radioresistance
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    Extracellular matrix-driven patient stratification and network modeling reveal distinct molecular grades with potential clinical implications
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    GFAT2-mediated HSPD1 O-GlcNAcylation drives chemotherapy resistance in non-small cell lung cancer
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    Constitutive EGFR activation induced by PTPRR downregulation confers resistance to KRAS inhibitors
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    Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R-Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression
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  28. Apr 2026
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXM1-specific TCR-engineered T cells target non-small cell lung cancer
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    IGF2R as a master regulator of acquired EGFR inhibitor resistance and therapeutic target in non-small cell lung cancer
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    A covalent molecular glue hijacks the E3 ligase MKRN2 to degrade the ribosomal protein RPS7 and induce synthetic lethality in p53-deficient NSCLC cells
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    Base Editing of TIGIT Reprograms CD155 Signaling in Natural Killer Cells to Enhance Cancer Immunotherapy Efficacy
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    HIF-1α siRNA Enhances the Efficacy of Erlotinib in Non-small Cell Lung Cancer: A Novel Strategy to Reverse Hypoxia-Induced Drug Resistance
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  36. Mar 2026
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    CCNB2, NUSAP1, GTSE1, and TK1: potential dual biomarkers for pneumonia and lung adenocarcinoma
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    EXAGO: An Argonaute-Based Primer-Free Exponential Amplification Strategy for Ultrasensitive Zero-Background Detection of Point Mutation
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    The STAT3–ZEB1 axis contributes to CCL2-mediated resistance to osimertinib in lung cancer
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  44. Feb 2026
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    SQSTM1/p62-mediated PD-L1 biomolecular condensate formation promotes lung tumorigenesis
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    Tumor Exosomal L1 Cell Adhesion Molecule Promotes Brain Metastasis of Lung Cancer
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    PARP inhibitor combined with platinum activates the cGAS-STING pathway to enhance anti-PD-L1 immunotherapy in lung adenocarcinoma
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  50. Jan 2026
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SERPINB3 enhances NPM1 sumoylation via inhibiting SENP3’s activity and promotes lung tumorigenesis
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    Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML
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    A combined strategy of EGFR-MET bispecific antibody and HER3 ADC to overcome osimertinib resistance in NSCLC
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    Profiling of Extracellular Vesicles of Non‐Small Cell Lung Cancer Reveals Proteins Associated With Osimertinib Resistance
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    ANP32A-mediated Histone 3 K27 Acetylation is Essential for Sotorasib Activity in KRAS-mutant Non-Small Cell Lung Cancer
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  58. Dec 2025
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  61. Nov 2025
  62. www.sciencedirect.com:5037 www.sciencedirect.com:5037
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  67. Oct 2025
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    Induction of a metabolic switch from glucose to ketone metabolism programs ketogenic diet-induced therapeutic vulnerability in lung cancer
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  73. Sep 2025
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    Notch3 mediated TGF-β1 activation enhances epithelial-mesenchymal transition and cancer stemness in non-small lung cancer
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  78. Aug 2025
  79. www.science.org www.science.org
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    EGFR Targeted Liposomal PROTAC Assisted With Epigenetic Regulation as an Efficient Strategy for Osimertinib-Resistant Lung Cancer Therapy
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    Preclinical Evaluation of DB-1419, a Novel Bifunctional and Bispecific Anti–B7-H3 × PD-L1 Antibody–Drug Conjugate
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    Dapk2 dysfunction leads to Mic60 lactylation and mitochondrial metabolic reprogramming, promoting lung cancer EGFR-TKI resistance and metastasis
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    FBXW5 Promotes Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Through the KLF13/TROAP Signaling Pathway
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.70018
  88. Jul 2025
  89. pubs.acs.org pubs.acs.org
    Novel Aptamer-Drug Conjugate for Targeted Therapy in Triple-Negative Breast Cancer
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    Utility of CK8/18 in identifying circulating tumor cells derived from lesions in patients with non-small cell lung cancer
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    STX-721, a Covalent EGFR/HER2 Exon 20 Inhibitor, Utilizes Exon 20–Mutant Dynamic Protein States and Achieves Unique Mutant Selectivity Across Human Cancer Models
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    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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    Strictosamide and mitraphylline inhibit cancer cell motility by suppressing epithelial-mesenchymal transition via integrin α4-mediated signaling
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