Hypothesis

34 Matching Annotations

Feb 2026
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Discovery of SKP2-Recruiting PROTACs for Target Protein Degradation

1
1. scibot 05 Feb 2026
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1002/advs.202515159
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515159
Jan 2026
www.sciencedirect.com www.sciencedirect.com

BRD2 bridges TFIID and MOF-H4K16ac-containing nucleosomes to promote transcriptional initiation

1
1. scibot 06 Jan 2026
  
  in Public
  
  ATCCCat# CRL-5911
  
  DOI: 10.1016/j.molcel.2025.12.010
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

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sciencedirect.com/science/article/pii/S1097276525009840
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SMURF2 facilitates GAP17 Isoform 1 membrane displacement to promote mutant p53-KRAS oncogenic synergy

1
1. scibot 06 Dec 2025
  
  in Public
  
  CVCL_1514
  
  DOI: 10.1158/1541-7786.MCR-24-0701
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12133423/
Jul 2025
www.sciencedirect.com www.sciencedirect.com

KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

1
1. scibot 15 Jul 2025
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1016/j.ccell.2025.06.011
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

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sciencedirect.com/science/article/pii/S1535610825002612
Jun 2025
www.sciencedirect.com www.sciencedirect.com

PLK1-mediated PDHA1 phosphorylation drives mitochondrial dysfunction, mitophagy, and cancer progression in Cr(VI)-associated lung cancer

1
1. scibot 24 Jun 2025
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1016/j.jbc.2025.110406
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

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sciencedirect.com/science/article/pii/S0021925825022562
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PDF-html.html

1
1. scibot 22 Jun 2025
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1016/j.isci.2025.112925
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12270665/
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma

1
1. scibot 29 Mar 2025
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1016/j.molcel.2025.03.001
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

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sciencedirect.com/science/article/pii/S1097276525001947
Feb 2025
www.sciencedirect.com www.sciencedirect.com

JNJ-78306358, a first-in-class bispecific T cell engaging antibody targeting CD3 and HLA-G

1
1. scibot 27 Feb 2025
  
  in Public
  
  ATCCCRL-5911
  
  DOI: 10.1016/j.isci.2025.111876
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S2589004225001361
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Single-cell and spatial transcriptomics reveal a potential role of ATF3 in brain metastasis of lung adenocarcinoma

1
1. scibot 16 Feb 2025
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.21037/tlcr-24-784
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11826269/
Jan 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225001245-main-html.html

1
1. scibot 23 Jan 2025
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1016/j.isci.2025.111864
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

52.53.155.43/b8347d751839197edb20fe1168219b4048f4b01d/1-s2.0-S2589004225001245-main-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Efficacy of CBP/p300 Dual Inhibitors against De-repression of KREMEN2 in cBAF-Deficient Cancers

1
1. scibot 08 Jan 2025
  
  in Public
  
  RRID: CVCL_1514
  
  DOI: 10.1158/2767-9764.CRC-24-0484
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11701801/
Nov 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment

1
1. scibot 12 Nov 2023
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1002/ijc.34783
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.34783
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Individualized tumor-informed circulating tumor DNA analysis for postoperative monitoring of non-small cell lung cancer

1
1. scibot 06 Oct 2023
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1016/j.ccell.2023.08.010
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S1535610823002866
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors

1
1. scibot 04 May 2023
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1158/0008-5472.CAN-22-3000
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Olfactory Receptor OR2H1 is an effective target for CAR T cells in human epithelial tumors

1
1. scibot 12 Jan 2023
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1158/1535-7163.MCT-21-0872
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9256805/
Sep 2022
www.sciencedirect.com www.sciencedirect.com

MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer

1
1. scibot 24 Sep 2022
  
  in Public
  
  CRL-5911
  
  DOI: 10.1016/j.ccell.2022.08.015
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S1535610822003798
Jul 2022
www.sciencedirect.com www.sciencedirect.com

FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma

1
1. scibot 15 Jul 2022
  
  in Public
  
  ATCCCat#CRL-5911
  
  DOI: 10.1016/j.devcel.2022.06.017
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S1534580722004580
Jun 2022
52.53.155.43 52.53.155.43

mct-21-0872-html.html

1
1. scibot 24 Jun 2022
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1158/1535-7163.mct-21-0872
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
  What is this?
  
  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

52.53.155.43/794634b08375e88cb30dbddf793317e31104a407/mct-21-0872-html.html
www.sciencedirect.com www.sciencedirect.com

Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi

1
1. scibot 22 Jun 2022
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1016/j.crmeth.2022.100239
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S2667237522001084
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes

1
1. scibot 14 Apr 2022
  
  in Public
  
  CVCL_1514
  
  DOI: 10.1016/j.celrep.2022.110636
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722003886
Dec 2021
www.sciencedirect.com www.sciencedirect.com

EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion

1
1. scibot 28 Dec 2021
  
  in Public
  
  CRL-5911
  
  DOI: 10.1016/j.cell.2021.12.005
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1514
  
  What is this?
  
  RRID:CVCL_1514 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S0092867421014276
Nov 2021
www.sciencedirect.com www.sciencedirect.com

FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma

1
1. scibot 03 Nov 2021
  
  in Public
  
  CRL-5911
  
  DOI: 10.1016/j.celrep.2021.109905
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1514
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1514
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RRIDCUR:Missing

RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721013759
Aug 2021
www.sciencedirect.com www.sciencedirect.com

RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1016/j.chembiol.2019.12.005
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1514
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1514
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RRID:CVCL_1514

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2451945619304015
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

1
1. scibot 30 Jul 2021
  
  in Public
  
  NCI-H2009
  
  DOI: 10.1016/j.celrep.2019.08.090
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1514
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1514
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RRIDCUR:Missing

RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719311520
www.sciencedirect.com www.sciencedirect.com

Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma

1
1. scibot 30 Jul 2021
  
  in Public
  
  H2009
  
  DOI: 10.1016/j.ccell.2019.07.002
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1514
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1514
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RRIDCUR:Missing

RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819303290
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis

1
1. scibot 30 Apr 2021
  
  in Public
  
  CVCL_1514
  
  DOI: 10.1016/j.cmet.2020.12.007
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1514
  
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  RRID:CVCL_1514
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RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S1550413120306628
Sep 2020
elifesciences.org elifesciences.org

Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

1
1. scibot 14 Sep 2020
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.7554/eLife.53367
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1514
  
  What is this?
  
  RRID:CVCL_1514 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1514

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scibot

URL

elifesciences.org/articles/53367
www.sciencedirect.com www.sciencedirect.com

Transite: A Computational Motif-Based Analysis Platform That Identifies RNA-Binding Proteins Modulating Changes in Gene Expression

1
1. scibot 08 Sep 2020
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.1016/j.celrep.2020.108064
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1514
  
  What is this?
  
  RRID:CVCL_1514 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720310494
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1514
  
  DOI: 10.7554/eLife.45572
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1514
  
  What is this?
  
  RRID:CVCL_1514 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1514

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6584702/
www.sciencedirect.com www.sciencedirect.com

Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1

1
1. scibot 13 Jan 2020
  
  in Public
  
  CVCL_1514
  
  DOI: 10.1016/j.cell.2019.06.003
  
  Resource: (KCLB Cat# 92009, RRID:CVCL_1514)
  
  Curator: @ethanbadger
  
  SciCrunch record: CVCL_1514
  
  What is this?
  
  RRID:CVCL_1514 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S0092867419306312
Nov 2018
www.sciencedirect.com www.sciencedirect.com

The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1514
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-5911, RRID:CVCL_1514)
  
  SciCrunch record: RRID:CVCL_1514
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1514 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S1074761318304357
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target

1
1. scibot 05 Nov 2018
  
  in Public
  
  NCI-H2009
  
  Curator: @anp055
  
  Resource used:
  
  (ATCC Cat# CRL-5911, RRID:CVCL_1514)
  
  SciCrunch record: RRID:CVCL_1514
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1514 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1514

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC3566312/
www.sciencedirect.com www.sciencedirect.com

Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-5911
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-5911, RRID:CVCL_1514)
  
  SciCrunch record: RRID:CVCL_1514
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1514 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S1535610818303696
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer

1
1. scibot 08 Nov 2017
  
  in Public
  
  CRL-5911
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-5911, RRID:CVCL_1514)
  
  SciCrunch record: RRID:CVCL_1514
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1514 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1514

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scibot

URL

sciencedirect.com/science/article/pii/S0092867417310474