38 Matching Annotations
  1. Aug 2025
  2. www.nature.com www.nature.com
    NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
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    nature.com/articles/s41586-025-09299-y
  3. www.sciencedirect.com www.sciencedirect.com
    Integrative analysis of lung adenocarcinoma across diverse ethnicities and exposures
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    sciencedirect.com/science/article/pii/S1535610825003174
  4. Jul 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Utility of CK8/18 in identifying circulating tumor cells derived from lesions in patients with non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12261347/
  6. www.sciencedirect.com www.sciencedirect.com
    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1535610825002612
  7. Jun 2025
  8. link.springer.com link.springer.com
    Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis
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    link.springer.com/article/10.1186/s40170-025-00400-7
  9. Apr 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11977641/
  11. Mar 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S1097276525001947
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape
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    pmc.ncbi.nlm.nih.gov/articles/PMC11832170/
  14. Feb 2025
  15. ar.iiarjournals.org ar.iiarjournals.org
    ALK Inhibitor and Chemotherapy Combinations in Models of ALK-Translocated NSCLC
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    ar.iiarjournals.org/content/44/7/2805
  16. Jan 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficacy of CBP/p300 Dual Inhibitors against De-repression of KREMEN2 in cBAF-Deficient Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11701801/
  18. Oct 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
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    sciencedirect.com/science/article/pii/S2451945624003969
  20. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Combined blockade of GPX4 and activated EGFR/HER3 bypass pathways inhibits the development of ALK-inhibitor-induced tolerant persister cells in ALK-fusion-positive lung cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13746
  21. Aug 2024
  22. www.tandfonline.com www.tandfonline.com
    The Targeting Effect of Cetuximab Combined with PD-L1 Blockade against EGFR-Expressing Tumors in a Tailored CD16-CAR T-Cell Reporter System
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    tandfonline.com/doi/full/10.1080/07357907.2021.1894570
  23. May 2024
  24. 52.53.155.43 52.53.155.43
    Therapeutic Implications of Ceritinib in Cholangiocarcinoma beyond ALK Expression and Mutation
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    52.53.155.43/3f07be0ebaa016d2b81ff2554651fc11f237f3a0/pharmaceuticals-17-00197-html.html
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy of EGFR and AURKA Inhibitors in KRAS-mutated Non–small Cell Lung Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078142/
  26. Apr 2024
  27. aacrjournals.org aacrjournals.org
    The immune suppressor IGSF1 as a potential target for cancer immunotherapy
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    aacrjournals.org/cancerimmunolres/article/12/4/491/741941/The-Immune-Suppressor-IGSF1-as-a-Potential-Target
  28. Mar 2024
  29. www.sciencedirect.com www.sciencedirect.com
    Silibinin is a suppressor of the metastasis-promoting transcription factor ID3
    1
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    sciencedirect.com/science/article/pii/S0944711324001570
  30. Feb 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR
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    sciencedirect.com/science/article/pii/S1534580724000303
  32. Nov 2023
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34783
  34. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13505
  35. Jun 2023
  36. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    nature.com/articles/s41467-023-39241-7
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical and prognostic significance of detecting CEA, EGFR, LunX, c-met and EpCAM mRNA-positive cells in the peripheral blood, tumor-draining blood and bone marrow of non-small cell lung cancer patients
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10261864/
  38. Apr 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
  40. Jan 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437570/
  42. Aug 2022
  43. 52.53.155.43 52.53.155.43
    cd-21-1671-html.html
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    52.53.155.43/5e67ddaf80a7b90ec85c4b24452e48b76eabacbf/cd-21-1671-html.html
  44. May 2022
  45. link.springer.com link.springer.com
    Integrated analysis of ALK higher expression in human cancer and downregulation in LUAD using RNA molecular scissors
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    link.springer.com/article/10.1007/s12094-022-02835-6
  46. Jan 2022
  47. www.sciencedirect.com www.sciencedirect.com
    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
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    sciencedirect.com/science/article/pii/S1535610821006620
  48. Nov 2021
  49. www.sciencedirect.com www.sciencedirect.com
    FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124721013759
  50. Sep 2021
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8394850/
  52. Jul 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion
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    sciencedirect.com/science/article/pii/S1550413119300208
  54. mcr.aacrjournals.org mcr.aacrjournals.org
    An IFNγ/STAT1/JMJD3 Axis Induces ZEB1 Expression and Promotes Aggressiveness in Lung Adenocarcinoma
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    mcr.aacrjournals.org/content/19/7/1234
  55. Jun 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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    sciencedirect.com/science/article/pii/S2211124721006628
  57. May 2021
  58. www.sciencedirect.com www.sciencedirect.com
    3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis
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    sciencedirect.com/science/article/pii/S1097276520306936
  59. Apr 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
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    sciencedirect.com/science/article/pii/S0092867420308746
  61. Sep 2020
  62. www.sciencedirect.com www.sciencedirect.com
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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    sciencedirect.com/science/article/pii/S2211124720308214
  63. www.mdpi.com www.mdpi.com
    Methylation Patterns and Chromatin Accessibility in Neuroendocrine Lung Cancer
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    mdpi.com/2072-6694/12/8/2003
  64. Jan 2020
  65. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion
    1
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    sciencedirect.com/science/article/pii/S1550413119300208
  66. Nov 2018
  67. europepmc.org europepmc.org
    Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.
    1
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    europepmc.org/articles/PMC5752523/