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SCLC humanized mice identify T cell infiltration phenotypes in response to combination immune-radiation therapies

1
1. scibot 27 Jul 2026
  
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  CVCL_1591
  
  DOI: 10.1016/j.isci.2026.116864
  
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sciencedirect.com/science/article/pii/S258900422602242X
Jul 2026
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ABL kinase inactivation induces transcription-replication conflicts and impairs replication fork progression in metastatic small cell lung cancer

1
1. scibot 16 Jul 2026
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.celrep.2026.117699
  
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sciencedirect.com/science/article/pii/S2211124726007771
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USP2 stabilizes POU2F3 and represents a therapeutic vulnerability in POU2F3-positive small cell lung cancer

1
1. scibot 06 Jul 2026
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.cpblue.2026.100071
  
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sciencedirect.com/science/article/pii/S3051383926000691
Mar 2026
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Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancer

1
1. scibot 06 Mar 2026
  
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  ATCCHTB-175
  
  DOI: 10.1016/j.ccell.2026.02.008
  
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sciencedirect.com/science/article/pii/S1535610826001066
Jan 2026
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c-JUN enhances CRISPR knockin anti-B7-H3 CAR T cell function in small cell lung cancer and thoracic SMARCA4-deficient undifferentiated tumors

1
1. scibot 22 Jan 2026
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.xcrm.2025.102549
  
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sciencedirect.com/science/article/pii/S2666379125006226
www.biorxiv.org www.biorxiv.org

KDM7B-mediated demethylation of RNF113A regulates small cell lung cancer sensitivity to alkylation damage

1
1. scibot 16 Jan 2026
  
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  RRID:CVCL_1591
  
  DOI: 10.64898/2026.01.03.697470
  
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biorxiv.org/content/10.64898/2026.01.03.697470v1
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

D3-GPC2-directed CAR T cells are safe and efficacious in preclinical models of neuroblastoma and small cell lung cancer

1
1. scibot 19 Dec 2025
  
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  RRID:CVCL_1591
  
  DOI: 10.1158/1078-0432.CCR-25-0089
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12699724/
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KSR1 mediates small-cell lung carcinoma tumor initiation and cisplatin resistance

1
1. scibot 06 Dec 2025
  
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  CVCL_1591
  
  DOI: 10.1158/1541-7786.MCR-24-0652
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12133430/
Sep 2025
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Sympathetic Neurons Promote Small Cell Lung Cancer Through the Beta-2 Adrenergic Receptor

1
1. scibot 07 Sep 2025
  
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  RRID:CVCL_1591
  
  DOI: 10.1158/2159-8290.CD-24-0718
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11875942/
Aug 2025
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Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancer

1
1. scibot 27 Aug 2025
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.devcel.2025.07.023
  
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sciencedirect.com/science/article/pii/S153458072500499X
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Engineering affinity-matured variants of an anti-polysialic acid monoclonal antibody with superior cytotoxicity-mediating potency

1
1. scibot 26 Aug 2025
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.chembiol.2025.07.007
  
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sciencedirect.com/science/article/pii/S2451945625002302
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Preclinical Evaluation of DB-1419, a Novel Bifunctional and Bispecific Anti–B7-H3 × PD-L1 Antibody–Drug Conjugate

1
1. scibot 16 Aug 2025
  
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  RRID:CVCL_1591
  
  DOI: 10.1158/1078-0432.CCR-25-0634
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12351279/
Jun 2025
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Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity

1
1. scibot 18 Jun 2025
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.jpet.2025.103634
  
  Resource: (RRID:CVCL_1591)
  
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sciencedirect.com/science/article/pii/S0022356525398472
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 14 Jun 2025
  
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  RRID:CVCL_1591
  
  DOI: 10.1158/1078-0432.ccr-25-0634
  
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52.53.155.43/bbb28230632658450b2bbad03fe0ee90e846e4ab/PDF-html.html
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung Cancer

1
1. scibot 15 Feb 2025
  
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  RRID:CVCL_1591
  
  DOI: 10.3390/ijms26031293
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11818609/
aacrjournals.org aacrjournals.org

ASCL1 restrains ERK1/2 to promote survival of a subset of neuroendocrine lung cancers

1
1. scibot 13 Feb 2025
  
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  RRID:CVCL_1591
  
  DOI: 10.1158/1535-7163.MCT-24-0355
  
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aacrjournals.org/mct/article/23/12/1789/750248/ASCL1-Restrains-ERK1-2-to-Promote-Survival-of-a
www.cell.com www.cell.com

1-s2.0-S2589004225002032-main-html.html

1
1. scibot 04 Feb 2025
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.isci.2025.111943
  
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cell.com/iscience/fulltext/S2589-0042(25)00203-2
Dec 2024
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Lurbinectedin sensitizes PD-L1 blockade therapy by activating STING-IFN signaling in small-cell lung cancer

1
1. scibot 10 Dec 2024
  
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  ATCCRRID: CVCL_1591
  
  DOI: 10.1016/j.xcrm.2024.101852
  
  Resource: (RRID:CVCL_1591)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S2666379124006232
Aug 2024
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Protocol for establishing spontaneous metastasis in mice using a subcutaneous tumor model

1
1. scibot 13 Aug 2024
  
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  Cat#HTB-175
  
  DOI: 10.1016/j.xpro.2024.103239
  
  Resource: (RRID:CVCL_1591)
  
  Curator: @vtello
  
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sciencedirect.com/science/article/pii/S2666166724004040
Jul 2024
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Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

1
1. scibot 25 Jul 2024
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.ccell.2024.06.012
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
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sciencedirect.com/science/article/pii/S153561082400237X
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Cisplatin resistance-related transcriptome and methylome integration identifies PCDHB4 as a novel prognostic biomarker in small cell lung cancer

1
1. scibot 19 Jul 2024
  
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  Cat# HTB-175
  
  DOI: 10.1016/j.isci.2024.110413
  
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sciencedirect.com/science/article/pii/S2589004224016389
May 2024
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Molecular and pathological characterization of YAP1-expressing small cell lung cancer cell lines leads to reclassification as SMARCA4-deficient malignancies

1
1. scibot 03 May 2024
  
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  RRID:CVCL_1591
  
  DOI: 10.1158/1078-0432.CCR-23-2360
  
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aacrjournals.org/clincancerres/article/30/9/1846/743134/Molecular-and-Pathologic-Characterization-of-YAP1
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Rejuvenated iPSC-derived GD2-directed CART Cells Harbor Robust Cytotoxicity Against Small Cell Lung Cancer

1
1. scibot 13 Mar 2024
  
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  RRID:CVCL_1591
  
  DOI: 10.1158/2767-9764.CRC-23-0259
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10926899/
Feb 2024
52.53.155.43 52.53.155.43

d1-html.html

1
1. scibot 29 Feb 2024
  
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  RRID:CVCL_1591
  
  DOI: 10.1158/1078-0432.ccr-23-2360
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
  Curator: @abever99
  
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52.53.155.43/9d9c84a50a37d03d2f105a9516b773f31c793012/d1-html.html
Jan 2024
www.sciencedirect.com www.sciencedirect.com

UCHL1 is a potential molecular indicator and therapeutic target for neuroendocrine carcinomas

1
1. scibot 20 Jan 2024
  
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  HTB-175
  
  DOI: 10.1016/j.xcrm.2023.101381
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S2666379123006109
Oct 2023
52.53.155.43 52.53.155.43

ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers

1
1. scibot 14 Oct 2023
  
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  RRID:CVCL_1591
  
  DOI: 10.1101/2023.06.15.545148
  
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52.53.155.43/3932de370933c2759897a986a0751f177eee572e/2023.06.15.545148v1.full-html.html
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors

1
1. scibot 04 May 2023
  
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  RRID:CVCL_1591
  
  DOI: 10.1158/0008-5472.CAN-22-3000
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

1
1. scibot 07 Jan 2023
  
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  RRID:CVCL_1591
  
  DOI: 10.1158/2159-8290.CD-21-0205
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9437563/
Sep 2022
www.jci.org www.jci.org

Hematopoietic transcription factor GFI1 promotes anchorage independence by sustaining ERK activity in cancer cells

1
1. scibot 30 Sep 2022
  
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  RRID:CVCL_1591
  
  DOI: 10.1172/JCI149551
  
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jci.org/articles/view/149551
Aug 2022
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Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer

1
1. scibot 22 Aug 2022
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.cels.2022.07.006
  
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sciencedirect.com/science/article/pii/S2405471222003131
May 2022
www.sciencedirect.com www.sciencedirect.com

WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

1
1. scibot 19 May 2022
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.celrep.2022.110814
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
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sciencedirect.com/science/article/pii/S221112472200585X
Nov 2021
www.nature.com www.nature.com

Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer

1
1. scibot 21 Nov 2021
  
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  RRID:CVCL_1591
  
  DOI: 10.1038/s41467-021-26823-6
  
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  Curator: @bandrow
  
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nature.com/articles/s41467-021-26823-6
Oct 2021
www.sciencedirect.com www.sciencedirect.com

MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer

1
1. scibot 29 Oct 2021
  
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  RRID:CVCL_1591
  
  DOI: 10.1016/j.isci.2021.103224
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
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sciencedirect.com/science/article/pii/S2589004221011925
Aug 2021
link.springer.com link.springer.com

YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models

1
1. scibot 28 Aug 2021
  
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  RRID:CVCL_1591
  
  DOI: 10.1007/s13402-021-00630-z
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
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link.springer.com/article/10.1007/s13402-021-00630-z
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer

1
1. scibot 11 Aug 2021
  
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  ATCCHTB-175
  
  DOI: 10.7554/eLife.66524
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1591
  
  What is this?
  
  RRID:CVCL_1591
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RRID:CVCL_1591

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8337080/
www.sciencedirect.com www.sciencedirect.com

ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

1
1. scibot 07 Aug 2021
  
  in Public
  
  HTB-175
  
  DOI: 10.1016/j.molcel.2021.07.018
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1591
  
  What is this?
  
  RRID:CVCL_1591 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1591

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scibot

URL

sciencedirect.com/science/article/pii/S1097276521005876
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

1
1. scibot 22 Jul 2021
  
  in Public
  
  RRID:CVCL_1591
  
  DOI: 10.1016/j.ccell.2021.06.016
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1591
  
  What is this?
  
  RRID:CVCL_1591
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RRID:CVCL_1591

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scibot

URL

sciencedirect.com/science/article/pii/S153561082100338X
www.sciencedirect.com www.sciencedirect.com

A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope

1
1. scibot 22 Jul 2021
  
  in Public
  
  RRID:CVCL_1591
  
  DOI: 10.1016/j.xcrm.2021.100344
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1591
  
  What is this?
  
  RRID:CVCL_1591
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RRID:CVCL_1591

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scibot

URL

sciencedirect.com/science/article/pii/S2666379121001932
Sep 2020
www.sciencedirect.com www.sciencedirect.com

MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:CVCL_1591
  
  DOI: 10.1016/j.ccell.2020.05.001
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1591
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1591
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RRIDCUR:Validated

RRID:CVCL_1591

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scibot

URL

sciencedirect.com/science/article/pii/S153561082030218X
www.sciencedirect.com www.sciencedirect.com

Near infrared photoimmunotherapy targeting DLL3 for small cell lung cancer

1
1. scibot 15 Sep 2020
  
  in Public
  
  RRID:CVCL_1591
  
  DOI: 10.1016/j.ebiom.2020.102632
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1591
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1591
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RRIDCUR:Validated

RRID:CVCL_1591

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scibot

URL

sciencedirect.com/science/article/pii/S2352396420300074
Jan 2020
www.sciencedirect.com www.sciencedirect.com

An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1591
  
  DOI: 10.1016/j.ccell.2019.08.008
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1591
  
  What is this?
  
  RRID:CVCL_1591 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1591

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819303769
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1591
  
  DOI: 10.1016/j.chembiol.2019.02.009
  
  Resource: (CLS Cat# 300442/p471_NCI-H82, RRID:CVCL_1591)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1591
  
  What is this?
  
  RRID:CVCL_1591 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1591

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URL

sciencedirect.com/science/article/pii/S2451945619300443
Nov 2018
www.sciencedirect.com www.sciencedirect.com

LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia

1
1. scibot 05 Nov 2018
  
  in Public
  
  HTB-175
  
  Curator: @Jmenke
  
  Resource used:
  
  (KCLB Cat# 30175, RRID:CVCL_1591)
  
  SciCrunch record: RRID:CVCL_1591
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1591 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1591

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scibot

URL

sciencedirect.com/science/article/pii/S1097276518301096
www.sciencedirect.com www.sciencedirect.com

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma

1
1. scibot 05 Nov 2018
  
  in Public
  
  HTB-175
  
  Curator: @Jmenke
  
  Resource used:
  
  (KCLB Cat# 30175, RRID:CVCL_1591)
  
  SciCrunch record: RRID:CVCL_1591
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1591 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1591

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scibot

URL

sciencedirect.com/science/article/pii/S0092867418310997