Hypothesis

27 Matching Annotations

Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Acquired resistance to the PRMT5 inhibitor confers collateral sensitivity to MEK inhibition in MTAP-null non-small cell lung cancer

1
1. scibot 10 Jun 2026
  
  in Public
  
  CVCL_1594
  
  DOI: 10.64898/2026.04.16.719008
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13131504/
www.sciencedirect.com www.sciencedirect.com

LKB1 inactivation elicits an NNMT-mediated methyl sink and confers dependence on PRMT5 in lung cancer

1
1. scibot 04 Jun 2026
  
  in Public
  
  ATCCCRL-5844
  
  DOI: 10.1016/j.celrep.2026.117487
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @nmaralla
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

sciencedirect.com/science/article/pii/S2211124726005656
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Acquired resistance to the PRMT5 inhibitor confers collateral sensitivity to MEK inhibition in MTAP-null non-small cell lung cancer

1
1. scibot 01 May 2026
  
  in Public
  
  CVCL_1594
  
  DOI: 10.64898/2026.04.16.719008
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13131504/
Aug 2025
www.biorxiv.org www.biorxiv.org

Engineering a Juxtamembrane-Targeting CAR T-Cell Against Mesothelin: A Novel Binder Resilient to Shed Antigen in Ovarian and Pancreatic Cancer

1
1. scibot 08 Aug 2025
  
  in Public
  
  CRL-5844
  
  DOI: 10.1101/2025.08.02.668276
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

biorxiv.org/content/10.1101/2025.08.02.668276v1
Jul 2025
www.sciencedirect.com www.sciencedirect.com

KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

1
1. scibot 15 Jul 2025
  
  in Public
  
  RRID:CVCL_1594
  
  DOI: 10.1016/j.ccell.2025.06.011
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825002612
May 2025
www.sciencedirect.com www.sciencedirect.com

MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer

1
1. scibot 20 May 2025
  
  in Public
  
  ATCCCat# CRL-5844
  
  DOI: 10.1016/j.celrep.2025.115722
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725004930
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification

1
1. scibot 16 May 2025
  
  in Public
  
  RRID:CVCL_159
  
  DOI: 10.1158/1535-7163.MCT-24-0386
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594 RRIDCUR:Unresolved
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RRID:CVCL_1594

RRIDCUR:Unresolved

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11962398/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2

1
1. scibot 04 Jan 2025
  
  in Public
  
  RRID:CVCL_1594
  
  DOI: 10.7554/eLife.89638
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11668523/
Oct 2024
www.sciencedirect.com www.sciencedirect.com

Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer

1
1. scibot 09 Oct 2024
  
  in Public
  
  Cat# CRL-5844
  
  DOI: 10.1016/j.chembiol.2024.09.004
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

sciencedirect.com/science/article/pii/S2451945624003969
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting AKR1B10 by drug repurposing with epalrestat overcomes chemoresistance in non-small cell lung cancer patient-derived tumor organoids

1
1. scibot 05 Sep 2024
  
  in Public
  
  RRID:CVCL_1594
  
  DOI: 10.1158/1078-0432.CCR-23-3980
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11369614/
May 2024
www.sciencedirect.com www.sciencedirect.com

Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers

1
1. scibot 17 May 2024
  
  in Public
  
  CRL-5844
  
  DOI: 10.1016/j.molcel.2024.04.009
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

sciencedirect.com/science/article/pii/S1097276524003241
Apr 2024
aacrjournals.org aacrjournals.org

The immune suppressor IGSF1 as a potential target for cancer immunotherapy

1
1. scibot 19 Apr 2024
  
  in Public
  
  RRID:CVCL_1594
  
  DOI: 10.1158/2326-6066.CIR-23-0817
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

aacrjournals.org/cancerimmunolres/article/12/4/491/741941/The-Immune-Suppressor-IGSF1-as-a-Potential-Target
Nov 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment

1
1. scibot 12 Nov 2023
  
  in Public
  
  RRID: CVCL_1594
  
  DOI: 10.1002/ijc.34783
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.34783
Sep 2023
www.sciencedirect.com www.sciencedirect.com

A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants

1
1. scibot 14 Sep 2023
  
  in Public
  
  RRID:CVCL_1594
  
  DOI: 10.1016/j.celrep.2023.113104
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723011154
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits

1
1. scibot 02 Nov 2022
  
  in Public
  
  RRID:CVCL_1594
  
  DOI: 10.1158/0008-5472.CAN-22-0671
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
Sep 2022
www.sciencedirect.com www.sciencedirect.com

De novo sphingolipid biosynthesis necessitates detoxification in cancer cells

1
1. scibot 29 Sep 2022
  
  in Public
  
  RRID:CVCL_1594
  
  DOI: 10.1016/j.celrep.2022.111415
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722012566
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases

1
1. scibot 18 Mar 2022
  
  in Public
  
  RRID:CVCL_1594
  
  DOI: 10.1016/j.isci.2022.103985
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy

1
1. scibot 05 Aug 2021
  
  in Public
  
  CRL-5844
  
  DOI: 10.1016/j.devcel.2021.07.006
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1594
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RRIDCUR:Missing

RRID:CVCL_1594

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580721005621
www.sciencedirect.com www.sciencedirect.com

RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_1594
  
  DOI: 10.1016/j.chembiol.2019.12.005
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1594
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RRIDCUR:Validated

RRID:CVCL_1594

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945619304015
Jul 2021
www.sciencedirect.com www.sciencedirect.com

BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID: CVCL_1594
  
  DOI: 10.1016/j.cell.2019.06.005
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

sciencedirect.com/science/article/pii/S0092867419306336
www.mdpi.com www.mdpi.com

Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor

1
1. scibot 29 Jul 2021
  
  in Public
  
  H838
  
  DOI: 10.3390/biom9070280
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1594
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RRIDCUR:Missing

RRID:CVCL_1594

Annotators

scibot

URL

mdpi.com/2218-273X/9/7/280/htm
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs

1
1. scibot 24 Apr 2021
  
  in Public
  
  CVCL_1594
  
  DOI: 10.1016/j.cell.2020.08.006
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867420309971
www.sciencedirect.com www.sciencedirect.com

Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:CVCL_1594
  
  DOI: 10.1016/j.ccell.2021.02.016
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1594
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

sciencedirect.com/science/article/pii/S1535610821001185
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Identification and Target-Modification of SL-BBI: A Novel Bowman–Birk Type Trypsin Inhibitor from Sylvirana latouchii

1
1. scibot 04 Sep 2020
  
  in Public
  
  H838
  
  DOI: 10.3390/biom10091254
  
  Resource: (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1594
  
  Curator comments: NCI-H838 cell line ATCC Cat# CRL-5844
  
  What is this?
  
  RRID:CVCL_1594 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1594

Annotators

scibot

URL

pubmed.ncbi.nlm.nih.gov/32872343/
Nov 2018
www.sciencedirect.com www.sciencedirect.com

N-Acetyl Cysteine Functions as a Fast-Acting Antioxidant by Triggering Intracellular H2S and Sulfane Sulfur Production

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-5844
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  SciCrunch record: RRID:CVCL_1594
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1594 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1594

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945618300333
onlinelibrary.wiley.com onlinelibrary.wiley.com

LOSS OF RUNX1 IS ASSOCIATED WITH AGGRESSIVE LUNG ADENOCARCINOMAS

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1594
  
  Resource used:
  
  (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  SciCrunch record: RRID:CVCL_1594
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1594
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RRID:CVCL_1594

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/jcp.26201/full
Nov 2017
www.sciencedirect.com www.sciencedirect.com

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment

1
1. scibot 08 Nov 2017
  
  in Public
  
  NCI-H838ATCCCat#CRL-5844
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-5844, RRID:CVCL_1594)
  
  SciCrunch record: RRID:CVCL_1594
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1594 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1594

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276517304069