66 Matching Annotations
  1. Nov 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCL26–CX3CR1 Axis Mediates a Feedback Loop between Cancer Cell and PMN-MDSCs to Promote CD8+ T Cell Exhaustion during Stomach Carcinogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12635414/
  3. Sep 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Pan-carcinoma sialyl-Tn-targeting expands CAR therapy to solid tumors
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    sciencedirect.com/science/article/pii/S2666379125004239
  5. Aug 2025
  6. www.sciencedirect.com www.sciencedirect.com
    Imaging and targeting S1PR1 in HER2+ tumors
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    sciencedirect.com/science/article/pii/S0969805125000666
  7. Jul 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Histone Deacetylase Inhibitor Entinostat Mediates HER2 Downregulation in Gastric Cancer, Providing the Basis for Its Particular Efficacy in HER2-Amplified Tumors and in Combination Therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12263226/
  9. aacrjournals.org aacrjournals.org
    Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates
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    aacrjournals.org/mct/article/23/4/541/741864/Development-of-a-Novel-DNA-Mono-alkylator-Platform
  10. Jun 2025
  11. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/3bda1409f18583fbce91bcb97f69f2102b694a35/PDF-html.html
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  13. www.sciencedirect.com www.sciencedirect.com
    Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy
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    sciencedirect.com/science/article/pii/S1934590925001870
  14. May 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Assessment of the Effects of Single-Domain Anti-Idiotypic Distribution Enhancers on the Disposition of Trastuzumab and on the Efficacy of a PE24-Trastuzumab Immunotoxin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12071152/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulation of HER2 internalization enhances single-dose antibody-drug potency in HER2+ gastric cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12081668/
  17. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Targeting PTBP3-Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202415983
  18. Apr 2025
  19. www.sciencedirect.com www.sciencedirect.com
    Expression characteristics and biological functions of CGB5 gene in gastric cancer
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    sciencedirect.com/science/article/pii/S0065128125000261
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Amanitin-Based Antibody–Drug Conjugates Targeting TROP2 for the Treatment of Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962393/
  21. Mar 2025
  22. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225005577-main-html.html
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  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical evaluation of a novel antibody–drug conjugate OBI-992 for Cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11906863/
  24. Feb 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11847841/
  26. 52.53.155.43 52.53.155.43
    1-s2.0-S258900422500224X-main-html.html
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  27. Jan 2025
  28. www.sciencedirect.com www.sciencedirect.com
    Acquired vulnerability against EGF receptor inhibition in gastric cancer promoted by class I histone deacetylase inhibitor entinostat
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    sciencedirect.com/science/article/pii/S1476558624001623
  29. www.sciencedirect.com www.sciencedirect.com
    The inhibition of SLC8A1 promotes Ca2+-dependent cell death in Gastric Cancer
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    sciencedirect.com/science/article/pii/S0753332224016743
  30. Dec 2024
  31. 52.53.155.43 52.53.155.43
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  32. Oct 2024
  33. aacrjournals.org aacrjournals.org
    Clinical and Immunologic Responses to a B-Cell Epitope Vaccine in Patients with HER2/neu-Overexpressing Advanced Gastric Cancer—Results from Phase Ib Trial IMU.ACS.001
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    aacrjournals.org/clincancerres/article/27/13/3649/671490/Clinical-and-Immunologic-Responses-to-a-B-Cell
  34. Sep 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase II trial of HER-Vaxx, a B cell peptide-based vaccine, in HER2-overexpressing advanced gastric cancer patients under platinum-based chemotherapy (HERIZON)
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393538/
  36. www.sciencedirect.com www.sciencedirect.com
    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
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    sciencedirect.com/science/article/pii/S2211124724010799
  37. Aug 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vorinostat Treatment of Gastric Cancer Cells Leads to ROS-Induced Cell Inhibition and a Complex Pattern of Molecular Alterations in Nrf2-Dependent Genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11357633/
  39. Jul 2024
  40. www.mdpi.com www.mdpi.com
    Define Critical Parameters of Trastuzumab-Mediated ADCC Assays via Assay Optimization Processes, Focusing on the Impact of Cryopreserved Effector Cells on Assay Performance
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    mdpi.com/2072-6694/16/13/2367
  41. May 2024
  42. aacrjournals.org aacrjournals.org
    Spatiotemporal quantification of HER2-targeting antibody-drug conjugate bystander activity and enhancement of solid tumor penetration
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    aacrjournals.org/clincancerres/article/30/5/984/734305/Spatiotemporal-Quantification-of-HER2-targeting
  43. www.sciencedirect.com www.sciencedirect.com
    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    sciencedirect.com/science/article/pii/S1097276524003241
  44. 52.53.155.43 52.53.155.43
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  45. Apr 2024
  46. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13654
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the receptor tyrosine kinase MerTK shows therapeutic value in gastric adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10974716/
  48. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    sciencedirect.com/science/article/pii/S0092867424003039
  49. Feb 2024
  50. 52.53.155.43 52.53.155.43
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  51. aacrjournals.org aacrjournals.org
    First-in-Human Study with preclinical data of BCL-2/BCL-xL Inhibitor Pelcitoclax in Locally Advanced or Metastatic Solid Tumors
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    aacrjournals.org/clincancerres/article/30/3/506/733551/First-in-Human-Study-with-Preclinical-Data-of-BCL
  52. www.cell.com www.cell.com
    Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
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    cell.com/cell/fulltext/S0092-8674(24)00006-0
  53. Jan 2024
  54. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Anchoring of hyaluronan glycocalyx to CD44 reduces sensitivity of HER2-positive gastric cancer cells to trastuzumab
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17069
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Therapeutic antibody targeting natriuretic peptide receptor 1 inhibits gastric cancer growth via BCL-2-mediated intrinsic apoptosis
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34831
  56. Dec 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel HER2-targeted therapy to overcome trastuzumab resistance in HER2-amplified gastric cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10730520/
  58. Sep 2023
  59. www.sciencedirect.com www.sciencedirect.com
    Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1
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    sciencedirect.com/science/article/pii/S0014482723002628
  60. Aug 2023
  61. 52.53.155.43 52.53.155.43
    Intl Journal of Cancer - 2023 - Cao-html.html
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    52.53.155.43/2b179ef2871af5f6fa0867fb9df0f25bba8c596d/Intl Journal of Cancer - 2023 - Cao-html.html
  62. Jul 2023
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KRAS activation in gastric cancer stem-like cells promotes tumor angiogenesis and metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10362758/
  64. Apr 2023
  65. aacrjournals.org aacrjournals.org
    Payload-binding Fab fragments increase the therapeutic index of MMAE antibody-drug conjugates
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    aacrjournals.org/mct/article/22/4/459/719018/Payload-Binding-Fab-Fragments-Increase-the
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
  67. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Ebselen oxide and derivatives are new allosteric HER2 inhibitors for HER2-positive cancers
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13419
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Targeting tumor vasculature to improve antitumor activity of T cells armed ex vivo with T cell engaging bispecific antibody
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    ncbi.nlm.nih.gov/pmc/articles/PMC10069597/
  69. Feb 2023
  70. www.sciencedirect.com www.sciencedirect.com
    VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer
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    sciencedirect.com/science/article/pii/S2352396423000166
  71. Dec 2022
  72. www.mdpi.com www.mdpi.com
    Alteration of Cellular Energy Metabolism through LPAR2-Axin2 Axis in Gastric Cancer
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    mdpi.com/2218-273X/12/12/1805
  73. Oct 2022
  74. www.nature.com www.nature.com
    Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies
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    nature.com/articles/s41467-022-33282-0
  75. Jul 2022
  76. www.medrxiv.org www.medrxiv.org
    Transcriptomic Profiling on Localized Gastric Cancer Identified CPLX1 as a Gene Promoting Malignant Phenotype of Gastric Cancer and a Predictor of Recurrence after Surgery and Subsequent Chemotherapy
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    medrxiv.org/content/10.1101/2021.03.25.21254204v1
  77. Jun 2022
  78. link.springer.com link.springer.com
    Transcriptomic profiling on localized gastric cancer identified CPLX1 as a gene promoting malignant phenotype of gastric cancer and a predictor of recurrence after surgery and subsequent chemotherapy
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    link.springer.com/article/10.1007/s00535-022-01884-6
  79. Mar 2022
  80. link.springer.com link.springer.com
    Lysosomal-associated membrane protein family member 5 promotes the metastatic potential of gastric cancer cells
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    link.springer.com/article/10.1007/s10120-022-01284-y
  81. Jan 2022
  82. www.dovepress.com www.dovepress.com
    <p>Dynamics of Endocytosis and Degradation of Antibody-Drug Conjugate T-DM1 in HER2 Positive Cancer Cells</p>
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    dovepress.com/dynamics-of-endocytosis-and-degradation-of-antibody-drug-conjugate-t-d-peer-reviewed-fulltext-article-DDDT
  83. Jul 2021
  84. mcr.aacrjournals.org mcr.aacrjournals.org
    KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis
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    mcr.aacrjournals.org/content/17/9/1945
  85. Local file Local file
    CCR-20-3742 3649..3660
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  86. Jun 2021
  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer
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    onlinelibrary.wiley.com/doi/10.1002/ctm2.454
  88. May 2021
  89. www.sciencedirect.com www.sciencedirect.com
    NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells
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    sciencedirect.com/science/article/pii/S2666379121001075
  90. www.mdpi.com www.mdpi.com
    Genetic and Epigenetic Alterations of CDH1 Regulatory Regions in Hereditary and Sporadic Gastric Cancer
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    mdpi.com/1424-8247/14/5/457
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN is a predictive biomarker of trastuzumab resistance and prognostic factor in HER2-overexpressing gastroesophageal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8079403/
  92. Apr 2021
  93. www.sciencedirect.com www.sciencedirect.com
    Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy
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    sciencedirect.com/science/article/pii/S2451945620302312
  94. Sep 2020
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7501074/
  96. mct.aacrjournals.org mct.aacrjournals.org
    ARX788, a Site-specific anti-HER2 Antibody Drug Conjugate, Demonstrates Potent and Selective Activity in HER2 Low and T-DM1 Resistant Breast and Gastric Cancers
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    mct.aacrjournals.org/content/19/9/1833
  97. www.sciencedirect.com www.sciencedirect.com
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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    sciencedirect.com/science/article/pii/S2211124720308214
  98. Jan 2020
  99. onlinelibrary.wiley.com onlinelibrary.wiley.com
    EphA2‐to‐YAP Pathway Drives Gastric Cancer Growth and Therapy Resistance
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32609
  100. Nov 2018
  101. www.sciencedirect.com www.sciencedirect.com
    Helicobacter pylori Employs a Unique Basolateral Type IV Secretion Mechanism for CagA Delivery
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    sciencedirect.com/science/article/pii/S1931312817303931
  102. www.sciencedirect.com www.sciencedirect.com
    Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade
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    sciencedirect.com/science/article/pii/S1535610818301740