Hypothesis

33 Matching Annotations

Mar 2026
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

BCR::ABL1-Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B-ALL Cells to Enhancer-Targeting Drugs

1
1. scibot 05 Mar 2026
  
  in Public
  
  CVCL_1650
  
  DOI: 10.1002/advs.202517231
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202517231
analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com

Disruption of Cytoskeleton Induces Physiologically and Morphologically Dysfunctional Mitochondria in B-ALL Cells

1
1. scibot 05 Mar 2026
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1002/cbf.70190
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/cbf.70190
Sep 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Enhancing Anti-Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression

1
1. scibot 27 Sep 2025
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1002/advs.202515472
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515472
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Probiotic-derived glucose oxidase exerts therapeutic efficacy against pediatric B-cell acute lymphoblastic leukemia

1
1. scibot 05 Aug 2025
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1016/j.biopha.2025.118436
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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sciencedirect.com/science/article/pii/S0753332225006304
Jul 2025
www.nature.com www.nature.com

Bioengineered immunocompetent preclinical trial-on-chip tool enables screening of CAR T cell therapy for leukaemia

1
1. scibot 03 Jul 2025
  
  in Public
  
  CRL-8286, ATCC
  
  DOI: 10.1038/s41551-025-01428-2
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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nature.com/articles/s41551-025-01428-2
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Development of a Novel Bifunctional Anti-CD47 Fusion Protein with Improved Efficacy and a Favorable Safety Profile

1
1. scibot 11 Jun 2025
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1158/1535-7163.MCT-24-0917
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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pmc.ncbi.nlm.nih.gov/articles/PMC12134747/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Highly specific Immunoproteasome inhibitor M3258 induces proteotoxic stress and apoptosis in KMT2A::AFF1 driven acute lymphoblastic leukemia

1
1. scibot 22 May 2025
  
  in Public
  
  RRID: CVCL_1650
  
  DOI: 10.1038/s41598-025-01657-0
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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pmc.ncbi.nlm.nih.gov/articles/PMC12089620/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

1
1. scibot 21 May 2025
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1002/1878-0261.13792
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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pmc.ncbi.nlm.nih.gov/articles/PMC12077275/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway

1
1. scibot 13 Mar 2025
  
  in Public
  
  CVCL_1650
  
  DOI: 10.21203/rs.3.rs-6017610/v1
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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pmc.ncbi.nlm.nih.gov/articles/PMC11875301/
Feb 2025
link.springer.com link.springer.com

Selective JAK2 pathway inhibition enhances anti-leukemic functionality in CD19 CAR-T cells

1
1. scibot 07 Feb 2025
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1007/s00262-024-03927-8
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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link.springer.com/article/10.1007/s00262-024-03927-8
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Novel immunotherapeutics against LGR5 to target multiple cancer types

1
1. scibot 25 Sep 2024
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1038/s44321-024-00121-2
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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ncbi.nlm.nih.gov/pmc/articles/PMC11393416/
www.sciencedirect.com www.sciencedirect.com

Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase

1
1. scibot 17 Sep 2024
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1016/j.canlet.2024.217242
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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scibot

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sciencedirect.com/science/article/pii/S0304383524006372
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

In vitro CAR-T cell killing: validation of the potency assay

1
1. scibot 06 Jul 2024
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1007/s00262-024-03753-y
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC11219661/
Mar 2024
www.sciencedirect.com www.sciencedirect.com

A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children

1
1. scibot 29 Mar 2024
  
  in Public
  
  Cat: CRL-8286
  
  DOI: 10.1016/j.xgen.2024.100526
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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URL

sciencedirect.com/science/article/pii/S2666979X24000685
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1016/j.ccell.2023.11.001
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @jmitrevska
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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URL

sciencedirect.com/science/article/pii/S1535610823003665
www.sciencedirect.com www.sciencedirect.com

Epigenomic mapping reveals distinct B cell acute lymphoblastic leukemia chromatin architectures and regulators

1
1. scibot 22 Nov 2023
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1016/j.xgen.2023.100442
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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URL

sciencedirect.com/science/article/pii/S2666979X2300277X
Jul 2023
www.sciencedirect.com www.sciencedirect.com

3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells

1
1. scibot 27 Jul 2023
  
  in Public
  
  RRID: CVCL_1650
  
  DOI: 10.1016/j.ejcb.2023.151343
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @olekpark
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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scibot

URL

sciencedirect.com/science/article/pii/S0171933523000584
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Siglec-15 promotes evasion of adaptive immunity in B-cell acute lymphoblastic leukemia

1
1. scibot 19 Jul 2023
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1158/2767-9764.CRC-23-0056
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC10351425/
52.53.155.43 52.53.155.43

crc-23-0056-html.html

1
1. scibot 13 Jul 2023
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1158/2767-9764.crc-23-0056
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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scibot

URL

52.53.155.43/a97c8d0b2c4db9c1d802055a62ec35907b04f0ad/crc-23-0056-html.html
Aug 2022
www.sciencedirect.com www.sciencedirect.com

hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia

1
1. scibot 17 Aug 2022
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1016/j.xcrm.2022.100717
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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URL

sciencedirect.com/science/article/pii/S2666379122002609
Jun 2022
www.frontiersin.org www.frontiersin.org

Low Prevalence of ETV6::RUNX1 Fusion Gene in a Hispanic Population

1
1. scibot 09 Jun 2022
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.3389/fped.2022.837656
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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URL

frontiersin.org/article/10.3389/fped.2022.837656/full
Mar 2022
www.sciencedirect.com www.sciencedirect.com

The KRAS-G12D mutation induces Metabolic Vulnerability in B-cell Acute Lymphoblastic Leukemia

1
1. scibot 02 Mar 2022
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1016/j.isci.2022.103881
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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scibot

URL

sciencedirect.com/science/article/pii/S2589004222001511
www.sciencedirect.com www.sciencedirect.com

Identification of new ETV6 modulators through a high throughput functional screening

1
1. scibot 02 Mar 2022
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1016/j.isci.2022.103858
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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scibot

URL

sciencedirect.com/science/article/pii/S2589004222001286
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses

1
1. scibot 19 Nov 2021
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1038/s41467-021-26771-1
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8586369/
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis

1
1. scibot 04 Sep 2021
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.7554/eLife.65872
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
Aug 2021
www.sciencedirect.com www.sciencedirect.com

ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

1
1. scibot 07 Aug 2021
  
  in Public
  
  CRL-8286
  
  DOI: 10.1016/j.molcel.2021.07.018
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1650
  
  What is this?
  
  RRID:CVCL_1650 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1650

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scibot

URL

sciencedirect.com/science/article/pii/S1097276521005876
Jul 2021
www.sciencedirect.com www.sciencedirect.com

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

1
1. scibot 31 Jul 2021
  
  in Public
  
  Human: Reh
  
  DOI: 10.1016/j.ccell.2019.11.001
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1650
  
  What is this?
  
  RRID:CVCL_1650 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1650

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819305215
www.nature.com www.nature.com

A kinase-independent role for CDK8 in BCR-ABL1 + leukemia

1
1. scibot 31 Jul 2021
  
  in Public
  
  ATCC no. CRL-8286
  
  DOI: 10.1038/s41467-019-12656-x
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1650

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URL

nature.com/articles/s41467-019-12656-x
www.sciencedirect.com www.sciencedirect.com

Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1016/j.celrep.2021.109460
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1650
  
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  RRID:CVCL_1650
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URL

sciencedirect.com/science/article/pii/S2211124721008834
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

1
1. scibot 20 Apr 2021
  
  in Public
  
  ACC 22
  
  DOI: 10.1016/j.molcel.2021.03.043
  
  Resource: (DSMZ Cat# ACC-22, RRID:CVCL_1650)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1650
  
  What is this?
  
  RRID:CVCL_1650 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1650

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scibot

URL

sciencedirect.com/science/article/pii/S1097276521002641
Sep 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Biomarker Profile for Prediction of Response to SMAC Mimetic Monotherapy in Pediatric Precursor B‐Cell Acute Lymphoblastic Leukemia

1
1. scibot 09 Sep 2020
  
  in Public
  
  RRID:CVCL_1650
  
  DOI: 10.1002/ijc.32799
  
  Resource: (ATCC Cat# CRL-8286, RRID:CVCL_1650)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1650
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1650
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RRIDCUR:Validated

RRID:CVCL_1650

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.32799
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Phenotyping and Target Expression Profiling of CD34+/CD38− and CD34+/CD38+ Stem- and Progenitor cells in Acute Lymphoblastic Leukemia

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID: CVCL_1650
  
  Curator: @evieth
  
  Resource used:
  
  (ATCC Cat# CRL-8286, RRID:CVCL_1650)
  Originally identified as: RRID: CVCL_1650
  
  SciCrunch record: RRID: CVCL_1650
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_1650
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RRID:CVCL_1650

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URL

sciencedirect.com/science/article/pii/S1476558618300885
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  REH
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (ATCC Cat# CRL-8286, RRID:CVCL_1650)
  
  SciCrunch record: RRID:CVCL_1650
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1650 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1650

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scibot

URL

sciencedirect.com/science/article/pii/S0092867416316853