Hypothesis

18 Matching Annotations

Jun 2025
www.sciencedirect.com www.sciencedirect.com

Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer

1
1. scibot 05 Jun 2025
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1016/j.chembiol.2025.05.004
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRID:CVCL_1661
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RRID:CVCL_1661

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scibot

URL

sciencedirect.com/science/article/pii/S2451945625001655
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours

1
1. scibot 23 Aug 2024
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1158/2767-9764.CRC-24-0113
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRID:CVCL_1661
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RRID:CVCL_1661

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11320025/
Feb 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

SAA1-dependent reprogramming of adipocytes by tumor cells is associated with triple negative breast cancer aggressiveness

1
1. scibot 07 Feb 2024
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1002/ijc.34859
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRID:CVCL_1661
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RRID:CVCL_1661

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scibot

URL

onlinelibrary.wiley.com/doi/full/10.1002/ijc.34859
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Clinical Implications of Sub-grouping HER2 Positive Tumors by Amplicon Structure and Co-amplified Genes

1
1. scibot 06 Aug 2021
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1038/s41598-019-55455-6
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRID:CVCL_1661
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RRID:CVCL_1661

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6906288/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells

1
1. scibot 02 Aug 2021
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1002/jcp.27013
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRID:CVCL_1661
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RRID:CVCL_1661

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6202151/
www.sciencedirect.com www.sciencedirect.com

Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

1
1. scibot 01 Aug 2021
  
  in Public
  
  CVCL_1661
  
  DOI: 10.1016/j.cels.2019.11.001
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1661
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RRIDCUR:Validated

RRID:CVCL_1661

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scibot

URL

sciencedirect.com/science/article/pii/S2405471219303874
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1016/j.cmet.2019.01.020
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRID:CVCL_1661 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1661

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scibot

URL

sciencedirect.com/science/article/pii/S1550413119300208
www.embopress.org www.embopress.org

CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling

1
1. scibot 30 Jul 2021
  
  in Public
  
  ZR‐75‐30
  
  DOI: 10.15252/embr.201948058
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1661
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RRIDCUR:Missing

RRID:CVCL_1661

Annotators

scibot

URL

embopress.org/doi/10.15252/embr.201948058
www.sciencedirect.com www.sciencedirect.com

Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target

1
1. scibot 01 Jul 2021
  
  in Public
  
  ZR-75-30
  
  DOI: 10.1016/j.biocel.2021.106028
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRID:CVCL_1661 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1661

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1357272521001060
May 2021
www.sciencedirect.com www.sciencedirect.com

Deciphering the signaling network of breast cancer improves drug sensitivity prediction

1
1. scibot 01 May 2021
  
  in Public
  
  CRL-1504
  
  DOI: 10.1016/j.cels.2021.04.002
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1661
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RRIDCUR:Missing

RRID:CVCL_1661

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405471221001113
Apr 2021
www.sciencedirect.com www.sciencedirect.com

The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells

1
1. scibot 20 Apr 2021
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1016/j.devcel.2021.03.008
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRID:CVCL_1661 RRIDCUR:Validated
Visit annotations in context

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RRIDCUR:Validated

RRID:CVCL_1661

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580721002057
Dec 2020
www.sciencedirect.com www.sciencedirect.com

Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth

1
1. scibot 24 Dec 2020
  
  in Public
  
  ZR75-30
  
  DOI: 10.1016/j.celrep.2020.108544
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1661
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:CVCL_1661

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720315333
Oct 2020
www.cell.com www.cell.com

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

1
1. scibot 18 Oct 2020
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1016/j.chembiol.2020.07.011
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRID:CVCL_1661 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:CVCL_1661

Annotators

scibot

URL

cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1016/j.cell.2020.05.053
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1661
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:CVCL_1661

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867420306863
onlinelibrary.wiley.com onlinelibrary.wiley.com

FGF13 promotes metastasis of triple‐negative breast cancer

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1002/ijc.32874
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1661
  
  Curator comments: ZR-75-30 cell line ATCC Cat# CRL-1504
  
  What is this?
  
  RRID:CVCL_1661
Visit annotations in context

Tags

RRID:CVCL_1661

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.32874
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1661
  
  DOI: 10.1016/j.cmet.2019.01.020
  
  Resource: (ECACC Cat# 88113004, RRID:CVCL_1661)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1661
  
  What is this?
  
  RRID:CVCL_1661 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:CVCL_1661

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413119300208
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

AhR ligand aminoflavone suppresses α6‐integrin–Src–Akt signaling to attenuate tamoxifen resistance in breast cancer cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1661
  
  Resource used:
  
  (ATCC Cat# CRL-1504, RRID:CVCL_1661)
  
  SciCrunch record: RRID:CVCL_1661
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1661
Visit annotations in context

Tags

RRID:CVCL_1661

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6202151/
www.sciencedirect.com www.sciencedirect.com

Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID: CVCL_1661
  
  Curator: @evieth
  
  Resource used:
  
  (ATCC Cat# CRL-1504, RRID:CVCL_1661)
  
  SciCrunch record: RRID:CVCL_1661
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1661 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:CVCL_1661

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405471218300541