10 Matching Annotations
  1. Sep 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PRKN mediates the ubiquitination of SCAF8 to reduce the mRNA stability of KLF5 and its transcriptional activation of EFNA3 in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13523511/
  3. Jul 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Beta-site Amyloid Precursor Protein Cleaving Enzyme 1 Overexpression Abrogates ST6GAL1 Mediated Rectal Cancer Chemoradiation Resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC13321710/
  5. Jun 2026
  6. www.sciencedirect.com www.sciencedirect.com
    Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS-mutant colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124726006376
  7. May 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glecirasib, a Potent and Selective Covalent KRAS G12C Inhibitor Exhibiting Synergism with Cetuximab or SHP2 Inhibitor JAB-3312
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    pmc.ncbi.nlm.nih.gov/articles/PMC12076188/
  9. Feb 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Selective WEE1 Inhibitor Azenosertib Shows Synergistic Antitumor Activity with KRASG12C Inhibitors in Preclinical Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11795354/
  11. Aug 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11310748/
  13. Jun 2023
  14. www.sciencedirect.com www.sciencedirect.com
    MEK inhibitor and anti-EGFR antibody overcome sotorasib resistance signals and enhance its antitumor effect in colorectal cancer cells
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    sciencedirect.com/science/article/pii/S030438352300215X
  15. Dec 2021
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach
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    pmc.ncbi.nlm.nih.gov/articles/PMC8867612/
  17. Nov 2018
  18. www.sciencedirect.com www.sciencedirect.com
    Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
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    sciencedirect.com/science/article/pii/S153561081830309X
  19. www.sciencedirect.com www.sciencedirect.com
    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
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    sciencedirect.com/science/article/pii/S0092867418300412