50 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12710464/
  3. Dec 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFN-γ-driven UBE2D3 upregulation impairs antigen presentation pathways and anti-tumor immunity in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12663187/
  5. Nov 2025
  6. www.nature.com www.nature.com
    KLF5 enables dichotomous lineage programs in pancreatic cancer via the AAA+ ATPase coactivators RUVBL1 and RUVBL2
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    nature.com/articles/s41467-025-66007-0
  7. Oct 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DUSP6 is upregulated in metastasis and influences migration and metabolism in pancreatic cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12484808/
  9. Sep 2025
  10. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511726
  11. Aug 2025
  12. www.sciencedirect.com www.sciencedirect.com
    A CD147-targeted small-molecule inhibitor potentiates gemcitabine efficacy by triggering ferroptosis in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2666379125003659
  13. Jul 2025
  14. www.sciencedirect.com www.sciencedirect.com
    A STAT3/integrin axis accelerates pancreatic cancer initiation and progression
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    sciencedirect.com/science/article/pii/S2211124725007818
  15. May 2025
  16. www.nature.com www.nature.com
    HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity
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    nature.com/articles/s41467-025-60129-1
  17. Apr 2025
  18. www.sciencedirect.com www.sciencedirect.com
    CD44 Identified as a Diagnostic Biomarker for Highly Malignant CA19-9 Negative Pancreatic Cancer
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    sciencedirect.com/science/article/pii/S0304383525002794
  19. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    PPY-Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202413432
  20. Dec 2024
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    B7-H3–Targeted CAR-Vδ1T Cells Exhibit Potent Broad-Spectrum Activity against Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609632/
  22. Oct 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CALB2 drives pancreatic cancer metastasis through inflammatory reprogramming of the tumor microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11448066/
  24. Aug 2024
  25. www.sciencedirect.com www.sciencedirect.com
    A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2211124724009835
  26. transmedcomms.biomedcentral.com transmedcomms.biomedcentral.com
    iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer
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    transmedcomms.biomedcentral.com/articles/10.1186/s41231-024-00161-3
  27. aacrjournals.org aacrjournals.org
    MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance
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    aacrjournals.org/mcr/article/21/5/444/726027/MYC-Glutamine-Dependency-Is-a-Therapeutic
  28. Jul 2024
  29. 52.53.155.43 52.53.155.43
    Cetylpyridinium chloride triggers paraptosis to suppress pancreatic tumor growth via the ERN1-MAP3K5-p38 pathway
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    52.53.155.43/3dc7aeecc5cd1b453f882be50c33db8a703a1bae/1-s2.0-S2589004224018236-main-html.html
  30. www.cell.com www.cell.com
    Pan-cancer proteogenomics expands the landscape of therapeutic targets
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    cell.com/cell/fulltext/S0092-8674(24)00583-X
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of autophagy induced by tetrandrine promotes the accumulation of reactive oxygen species and sensitizes efficacy of tetrandrine in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11238362/
  32. Apr 2024
  33. jhoonline.biomedcentral.com jhoonline.biomedcentral.com
    Heterodimerization of T cell engaging bispecific antibodies to enhance specificity against pancreatic ductal adenocarcinoma
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    jhoonline.biomedcentral.com/articles/10.1186/s13045-024-01538-5
  34. Feb 2024
  35. 52.53.155.43 52.53.155.43
    176-html.html
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    52.53.155.43/2ec0d88e67b798a89b6c5516dbe547b3b2c5ce80/176-html.html
  36. aacrjournals.org aacrjournals.org
    Mitochondrial translocase TOMM22 is overexpressed in pancreatic cancer and promotes aggressive growth by modulating mitochondrial protein import and function
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    aacrjournals.org/mcr/article/22/2/197/733695/Mitochondrial-Translocase-TOMM22-Is-Overexpressed
  37. www.sciencedirect.com www.sciencedirect.com
    Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy
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    sciencedirect.com/science/article/abs/pii/S0304383524000892
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nudt21-mediated alternative polyadenylation of MZT1 3’UTR contributes to pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831950/
  39. Jan 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin B6 competition in the tumor microenvironment hampers antitumor functions of NK cells.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10784745/
  41. Dec 2023
  42. 52.53.155.43 52.53.155.43
    mcr-23-0138-html.html
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    52.53.155.43/35aec9dc6d388b7cf372e8caf56749d4ccbc7935/mcr-23-0138-html.html
  43. Nov 2023
  44. www.sciencedirect.com www.sciencedirect.com
    In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin
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    sciencedirect.com/science/article/pii/S2451945623003252
  45. www.embopress.org www.embopress.org
    MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression
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    embopress.org/doi/full/10.15252/embj.2023114558
  46. Sep 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/abs/pii/S0304383523003622
  48. Jun 2023
  49. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  50. May 2023
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  52. Dec 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Cell Derived Exosomal GOT1 Suppresses Tumor Cell Ferroptosis to Accelerate Pancreatic Cancer Progression by Activating Nrf2/HO-1 Axis via Upregulating CCR2 Expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9735520/
  54. Jun 2022
  55. www.sciencedirect.com www.sciencedirect.com
    GPR120 promotes metastasis but inhibits tumor growth in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S1424390322001983
  56. Mar 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
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    ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
  58. cmbl.biomedcentral.com cmbl.biomedcentral.com
    TMEM43 promotes pancreatic cancer progression by stabilizing PRPF3 and regulating RAP2B/ERK axis
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    cmbl.biomedcentral.com/articles/10.1186/s11658-022-00321-z
  59. Dec 2021
  60. www.sciencedirect.com www.sciencedirect.com
    CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
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    sciencedirect.com/science/article/pii/S2211124721015461
  61. Aug 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of Long Noncoding RNA AL161431.1 in the Development and Progression of Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8363261/
  63. Jul 2021
  64. www.sciencedirect.com www.sciencedirect.com
    EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis
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    sciencedirect.com/science/article/pii/S153458071930485X
  65. www.sciencedirect.com www.sciencedirect.com
    KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
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    sciencedirect.com/science/article/pii/S1535610818304677
  66. Jun 2021
  67. www.sciencedirect.com www.sciencedirect.com
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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    sciencedirect.com/science/article/pii/S2211124721006628
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long non-coding RNA ELFN1-AS1 in the pathogenesis of pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8184490/
  69. May 2021
  70. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15435
  71. www.sciencedirect.com www.sciencedirect.com
    SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
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    sciencedirect.com/science/article/pii/S1097276521002690
  72. www.sciencedirect.com www.sciencedirect.com
    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
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    sciencedirect.com/science/article/pii/S1550413121001108
  73. Apr 2021
  74. www.sciencedirect.com www.sciencedirect.com
    Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
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    sciencedirect.com/science/article/pii/S0092867420313222
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long non-coding RNA PART1 predicts a poor prognosis and promotes the malignant progression of pancreatic cancer by sponging miR-122
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    ncbi.nlm.nih.gov/pmc/articles/PMC8053290/
  76. Nov 2020
  77. www.authorea.com www.authorea.com
    Natural Product Trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer
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    authorea.com/users/368637/articles/487712-natural-product-trienomycin-a-is-a-stat3-pathway-inhibitor-that-exhibits-potent-in-vitro-and-in-vivo-efficacy-against-pancreatic-cancer
  78. Sep 2020
  79. www.sciencedirect.com www.sciencedirect.com
    Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
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    sciencedirect.com/science/article/pii/S2211124720307440
  80. Nov 2018
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of RBF1 changes glutamine catabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC3566311/