109 Matching Annotations
  1. Oct 2026
  2. 54.241.53.176 54.241.53.176
    feb470321-sup-0001-supinfo-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    54.241.53.176/0a435b08ab5ccb0130a494e1092e43ce7911f0be/feb470321-sup-0001-supinfo-html.html
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12866144/
  4. Sep 2026
  5. www.tandfonline.com www.tandfonline.com
    Mitochondrial-Mediated Apoptosis and Anti-Leukemic Effects of Tocotrienol Within the Protective Bone Marrow Microenvironment
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    tandfonline.com/doi/full/10.1080/01635581.2026.2713789
  6. www.sciencedirect.com www.sciencedirect.com
    5-Azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276526005873
  7. www.nature.com www.nature.com
    PTBP1 controls oncogenic transcript processing and maintenance of acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41375-026-03098-8
  8. Jul 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting SMC3 deacetylation synergizes with XPO1 inhibition to reprogram the epigenetic landscape and suppress NPM1-mutated acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13408497/
  10. www.sciencedirect.com www.sciencedirect.com
    A structure-based modeling approach identifies effective drug combinations for RAS-mutant acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004226022534
  11. aacrjournals.org aacrjournals.org
    Cancer Susceptibility to Stapled Oncolytic Peptides is Dictated by Membrane Cholesterol and Inflammatory Signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/cancerres/article/86/11/2810/785298/Cancer-Susceptibility-to-Stapled-Oncolytic
  12. Jun 2026
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting BMP and TAZ/TEAD mechanotransduction pathways impairs acute myeloid leukemia chemoresistance
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13233328/
  14. May 2026
  15. www.sciencedirect.com www.sciencedirect.com
    Novel noscapine derivative induces AML differentiation by dual-engaging DHODH and mitochondrial lipids to trigger a metabolic–epigenetic–transcriptional cascade
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211383526003126
  16. www.sciencedirect.com www.sciencedirect.com
    LDLRAD2 drives glycolysis and angiogenesis to promote extramedullary infiltration in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004226013623
  17. www.sciencedirect.com www.sciencedirect.com
    Leukemic stem cell subtypes determine venetoclax resistance and therapeutic vulnerabilities in AML
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590926001529
  18. Apr 2026
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Base Editing of TIGIT Reprograms CD155 Signaling in Natural Killer Cells to Enhance Cancer Immunotherapy Efficacy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13080321/
  20. Mar 2026
  21. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70508
  22. Jan 2026
  23. www.biorxiv.org www.biorxiv.org
    BCLAF1 links RNA splicing to ATF4-dependent metabolic adaptation in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.64898/2026.01.19.700325v1
  24. www.sciencedirect.com www.sciencedirect.com
    Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S221112472501647X
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12866144/
  26. www.sciencedirect.com www.sciencedirect.com
    Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2451945625003952
  27. Dec 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12717831/
  29. Nov 2025
  30. www.sciencedirect.com www.sciencedirect.com
    Precision prediction of venetoclax-azacitidine treatment efficacy in acute myeloid leukemia via integrative drug screening and machine learning
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379125005348
  31. www.sciencedirect.com www.sciencedirect.com
    Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867425012334
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SOCS1 Protects Acute Myeloid Leukemia against Allogeneic T Cell–Mediated Cytotoxicity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12050964/
  33. Oct 2025
  34. www.biorxiv.org www.biorxiv.org
    Balancing Activation and Repression: CoREST-p300 Antagonism Controls Retinoic Acid-Driven Differentiation in AML
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2025.10.13.682235v1
  35. www.science.org www.science.org
    Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/sciadv.adx8662
  36. Aug 2025
  37. www.nature.com www.nature.com
    Retinoic acid disrupts an NPM1c/ROS/SENP3/ARF oncogenic axis in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41375-025-02731-2
  38. www.nature.com www.nature.com
    The bispecific innate cell engager AFM28 eliminates CD123+ leukemic stem and progenitor cells in AML and MDS
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41467-025-63069-y
  39. www.sciencedirect.com www.sciencedirect.com
    A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276525006513
  40. Jul 2025
  41. aacrjournals.org aacrjournals.org
    miR-196b-TLR7/8 signaling axis regulates innate immune signaling and myeloid maturation in DNMT3A-mutant AML
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/clincancerres/article/28/20/4574/709597/miR-196b-TLR7-8-Signaling-Axis-Regulates-Innate
  42. Jun 2025
  43. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Peptidomimetics Targeting the Amyloidogenicity of Nucleophosmin 1 Mutations in Acute Myeloid Leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.202500306
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
  45. May 2025
  46. www.cell.com www.cell.com
    CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00221-6
  47. Apr 2025
  48. www.biorxiv.org www.biorxiv.org
    TTLL4 glutamyltransferase is a therapeutic target for NPM1-mutated acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2025.04.07.647605v1
  49. Mar 2025
  50. www.sciencedirect.com www.sciencedirect.com
    A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610825001084
  51. www.nature.com www.nature.com
    Superior preclinical efficacy of co-treatment with BRG1/BRM and FLT3 inhibitor against AML cells with FLT3 mutations
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41408-025-01251-7
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11875301/
  53. Feb 2025
  54. www.sciencedirect.com www.sciencedirect.com
    BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0006497124004543
  55. www.sciencedirect.com www.sciencedirect.com
    PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590925000104
  56. 52.53.155.43 52.53.155.43
    PDF-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/b6e42261d11f7c0ae043c89c64cba240f59a1523/PDF-html.html
  57. Dec 2024
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    B7-H3–Targeted CAR-Vδ1T Cells Exhibit Potent Broad-Spectrum Activity against Solid Tumors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11609632/
  59. Oct 2024
  60. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13722
  61. aacrjournals.org aacrjournals.org
    Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/bloodcancerdiscov/article/2/5/518/665838/Monocytic-Differentiation-and-AHR-Signaling-as
  62. Sep 2024
  63. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17263
  64. Aug 2024
  65. www.cell.com www.cell.com
    SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
  66. Jun 2024
  67. link.springer.com link.springer.com
    β-Carboline derivatives are potent against Acute Myeloid Leukemia in vitro and in vivo
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s43440-024-00614-4
  68. www.sciencedirect.com www.sciencedirect.com
    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379124002842
  69. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    molecular-cancer.biomedcentral.com/articles/10.1186/s12943-024-02034-7
  70. Apr 2024
  71. www.sciencedirect.com www.sciencedirect.com
    Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610824001284
  72. Mar 2024
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FEBS Press
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11467801/
  75. Feb 2024
  76. www.biorxiv.org www.biorxiv.org
    BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2023.09.28.560054v1
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10524644/
  78. Jan 2024
  79. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13584
  80. Dec 2023
  81. www.biorxiv.org www.biorxiv.org
    MYC–NFATC2 axis maintains cell cycle and mitochondrial function in AML cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2023.11.15.567209v1
  82. Nov 2023
  83. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610823003665
  84. www.sciencedirect.com www.sciencedirect.com
    An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723014961
  85. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379123004846
  86. Sep 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
  88. 52.53.155.43 52.53.155.43
    Downregulation of RCN1 promotes pyroptosis in acute myeloid leukemia cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/17d9d464af1d04aab32a8e6f8ff8e2dac32e6481/Molecular Oncology - 2023 - Deng-html.html
  89. www.nature.com www.nature.com
    Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41375-022-01755-2
  90. www.sciencedirect.com www.sciencedirect.com
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723011099
  91. www.sciencedirect.com www.sciencedirect.com
    PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379123003580
  92. Aug 2023
  93. www.sciencedirect.com www.sciencedirect.com
    TSC22D3 as an immune-related prognostic biomarker for acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004223015286
  94. Apr 2023
  95. www.nature.com www.nature.com
    Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41408-023-00826-6
  96. Mar 2023
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
  98. Feb 2023
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptionally imprinted glycomic signatures of acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC9926860/
  100. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13368
  101. aacrjournals.org aacrjournals.org
    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
  102. Nov 2022
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC9645811/
  104. Sep 2022
  105. www.sciencedirect.com www.sciencedirect.com
    Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610822004366
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC9448541/
  107. www.hindawi.com www.hindawi.com
    Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    hindawi.com/journals/jo/2022/2813938/
  108. Aug 2022
  109. www.sciencedirect.com www.sciencedirect.com
    Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722010580
  110. www.sciencedirect.com www.sciencedirect.com
    A tubulin binding molecule drives differentiation of acute myeloid leukemia cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004222010598
  111. May 2022
  112. www.sciencedirect.com www.sciencedirect.com
    Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590922001606
  113. Apr 2022
  114. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867422003403
  115. aacrjournals.org aacrjournals.org
    Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
  116. Mar 2022
  117. www.sciencedirect.com www.sciencedirect.com
    The proteogenomic subtypes of acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610822000587
  118. Feb 2022
  119. www.sciencedirect.com www.sciencedirect.com
    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276522000570
  120. Jan 2022
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8752621/
  122. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721017423
  123. Sep 2021
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8462123/
  125. Aug 2021
  126. link.springer.com link.springer.com
    The BET bromodomain inhibitor ZEN-3365 targets the Hedgehog signaling pathway in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s00277-021-04602-z
  127. www.sciencedirect.com www.sciencedirect.com
    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276521005876
  128. Jul 2021
  129. www.sciencedirect.com www.sciencedirect.com
    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S153561082100338X
  130. Jun 2021
  131. www.sciencedirect.com www.sciencedirect.com
    ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276521003658
  132. May 2021
  133. www.sciencedirect.com www.sciencedirect.com
    A systematic analysis of signaling reactivation and drug resistance
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S221112472100499X
  134. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S009286742100502X
  135. www.sciencedirect.com www.sciencedirect.com
    Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721004356
  136. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Targeting DNA damage repair functions of two histone deacetylases, HDAC8 and SIRT6, sensitizes acute myeloid leukemia to NAMPT inhibition
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    clincancerres.aacrjournals.org/content/27/8/2352
  137. Apr 2021
  138. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610820305419
  139. www.sciencedirect.com www.sciencedirect.com
    MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610821001082
  140. www.sciencedirect.com www.sciencedirect.com
    Immunogenomic Landscape of Hematological Malignancies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610820302750
  141. Mar 2021
  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC7886351/
  143. Feb 2021
  144. www.sciencedirect.com www.sciencedirect.com
    Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379121000136
  145. Jan 2021
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC7116590/
  147. Sep 2020
  148. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC7397863/
  149. www.cell.com www.cell.com
    The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/cancer-cell/fulltext/S1535-6108(18)30375-1
  150. www.sciencedirect.com www.sciencedirect.com
    Vitamin D Receptor Controls Cell Stemness in Acute Myeloid Leukemia and in Normal Bone Marrow
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124719317127
  151. Jan 2020
  152. www.sciencedirect.com www.sciencedirect.com
    HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610819304854
  153. www.sciencedirect.com www.sciencedirect.com
    A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610818304707
  154. Nov 2018
  155. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124718314086
  156. www.sciencedirect.com www.sciencedirect.com
    Mutant NPM1 Maintains the Leukemic State through HOX Expression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610818303593
  157. www.sciencedirect.com www.sciencedirect.com
    CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610818302216
  158. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610818300126
  159. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610817305020
  160. www.sciencedirect.com www.sciencedirect.com
    Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610817305159
  161. Nov 2017
  162. www.sciencedirect.com www.sciencedirect.com
    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610817303641
  163. www.sciencedirect.com www.sciencedirect.com
    Sam68 Allows Selective Targeting of Human Cancer Stem Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2451945617301897