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    Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux
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    sciencedirect.com/science/article/pii/S0092867425015028
  3. Dec 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFN-γ-driven UBE2D3 upregulation impairs antigen presentation pathways and anti-tumor immunity in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12663187/
  5. Nov 2025
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    KLF5 enables dichotomous lineage programs in pancreatic cancer via the AAA+ ATPase coactivators RUVBL1 and RUVBL2
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    nature.com/articles/s41467-025-66007-0
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    OCIAD2-IQGAP1 interaction promotes pancreatic cancer progression by suppressing oxidative stress and mitochondria-mediated apoptosis
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    sciencedirect.com/science/article/pii/S0898656825006321
  8. Oct 2025
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    Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12533583/
  10. Jul 2025
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    Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time
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    pmc.ncbi.nlm.nih.gov/articles/PMC12288891/
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    A novel defined manganese metabolism‑related gene signature for predicting the prognosis of pancreatic ductal adenocarcinoma
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    Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins
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    science.org/doi/10.1126/science.adq8331
  14. May 2025
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    HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity
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    nature.com/articles/s41467-025-60129-1
  16. Apr 2025
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    PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma
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  18. Jan 2025
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  20. Oct 2024
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    Inactivation of HIPK2 attenuates KRASG12D activity and prevents pancreatic tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11437985/
  22. Sep 2024
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    Induction of oxidative- and endoplasmic-reticulum-stress dependent apoptosis in pancreatic cancer cell lines by DDOST knockdown
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369111/
  24. Aug 2024
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    Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347226/
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  27. Apr 2024
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    BUB1 Promotes Gemcitabine Resistance in Pancreatic Cancer Cells by Inhibiting Ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11048608/
  29. Mar 2024
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    FEBS Press
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    52.53.155.43/47007dbc2cda4f961c79d2e8158521ca8af7c5b7/Molecular Oncology - 2023 - Bots - Preclinical evaluation of the gorilla-derived HAdV-B AdV-lumc007 oncolytic adenovirus -html.html
  32. Jan 2024
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    Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17058
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    Autotaxin–lysolipid signaling suppresses a CCL11–eosinophil axis to promote pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10899115/
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    Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10756117/
  36. Oct 2023
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10549224/
  38. May 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  40. Apr 2023
  41. www.science.org www.science.org
    An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation
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    science.org/doi/10.1126/sciadv.adf8966
  42. Jan 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel B7-H6–Targeted IgG-Like T Cell–Engaging Antibody for the Treatment of Gastrointestinal Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9713360/
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    NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer
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    nature.com/articles/s41419-022-05535-9
  45. Dec 2022
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9737747/
  47. Sep 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437572/
  49. Feb 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC and MIZ1-dependent vesicular transport of double-strand RNA controls immune evasion in pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7611539/
  51. Jan 2022
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    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
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    sciencedirect.com/science/article/pii/S2211124721017459
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyaluronic acid fuels pancreatic cancer cell growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC8730721/
  54. Nov 2021
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    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    sciencedirect.com/science/article/pii/S2211124721015424
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    A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer
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    sciencedirect.com/science/article/pii/S004520682100883X
  57. Oct 2021
  58. www.nature.com www.nature.com
    Analysis of clonogenic growth in vitro
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    nature.com/articles/s41596-021-00615-0
  59. Jun 2021
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Gain-of-Function p53 R248W Mutant Promotes Migration by STAT3 Deregulation in Human Pancreatic Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8226097/
  61. Apr 2021
  62. www.sciencedirect.com www.sciencedirect.com
    Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
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    sciencedirect.com/science/article/pii/S0092867420313222
  63. Oct 2020
  64. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer
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    pubmed.ncbi.nlm.nih.gov/33027658/
  65. Sep 2020
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    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
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    sciencedirect.com/science/article/pii/S0092867420302701
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    Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33137
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    Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
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    link.springer.com/article/10.1186/s40170-019-0202-2
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS
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    ncbi.nlm.nih.gov/pmc/articles/PMC6952431/
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    Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells
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    mdpi.com/2072-6694/12/6/1643
  71. Jan 2020
  72. www.nature.com www.nature.com
    Untitled document
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    nature.com/articles/s41388-019-0810-x
  73. Nov 2017
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    Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
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    sciencedirect.com/science/article/pii/S109727651730312X