59 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Selective AUTAC‐mediated ATP7B degradation unlocks cuproptosis vulnerability in pancreatic ductal adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13714097/
  3. Sep 2026
  4. link.springer.com link.springer.com
    KDM6A loss enhances oxidative phosphorylation uncovering tissue-level convergent evolution
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    link.springer.com/article/10.1038/s44318-026-00891-0
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PRMT5 inhibitor-induced adaptation in pancreatic cancer with the RBM39 degrader indisulam
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    pmc.ncbi.nlm.nih.gov/articles/PMC13530115/
  6. Aug 2026
  7. www.sciencedirect.com www.sciencedirect.com
    Targeting addiction to HMGB2-driven transcriptional programs in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2211124726007278
  8. Jul 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibiting Fatty Acid Oxidation Reverses Autophagy-Mediated Acquired Chemotherapy Resistance in Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13324344/
  10. 54.241.53.176 54.241.53.176
    koe-et-al-2026-n-linked-glycosylation-regulates-snat2-trafficking-and-stability-in-pancreatic-ductal-adenocarcinoma-html.html
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    54.241.53.176/92e8acfcbd89398cad71ee7f85cc54b6eafd6123/koe-et-al-2026-n-linked-glycosylation-regulates-snat2-trafficking-and-stability-in-pancreatic-ductal-adenocarcinoma-html.html
  11. Jun 2026
  12. www.biorxiv.org www.biorxiv.org
    Mitochondrial degradation of metallothionein enables local zinc mobilization during zinc limitation
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    biorxiv.org/content/10.64898/2026.06.09.731205v1
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PI3K Regulates Wild-type RAS Signaling to Confer Resistance to KRAS Inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC13237827/
  14. May 2026
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hui-Xiang Decoction Against Pancreatic Cancer by Regulating AKT and Activating the Hippo Signaling Pathway
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    onlinelibrary.wiley.com/doi/full/10.1002/cbdv.202502356
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining ferroptosis inducers with gemcitabine to enhance treatment efficacy in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13185238/
  17. Apr 2026
  18. www.sciencedirect.com www.sciencedirect.com
    GLIS3 marks a neural-like progenitor cell state that drives metastasis in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S221112472600392X
  19. Mar 2026
  20. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    A Metal-Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202519898
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    DPP4 suppresses pancreatic cancer growth by enhancing ferroptosis sensitivity through stabilization of ACSL4
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    sciencedirect.com/science/article/pii/S0898656826000963
  22. Feb 2026
  23. www.sciencedirect.com www.sciencedirect.com
    Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux
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    sciencedirect.com/science/article/pii/S0092867425015028
  24. Dec 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFN-γ-driven UBE2D3 upregulation impairs antigen presentation pathways and anti-tumor immunity in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12663187/
  26. Nov 2025
  27. www.nature.com www.nature.com
    KLF5 enables dichotomous lineage programs in pancreatic cancer via the AAA+ ATPase coactivators RUVBL1 and RUVBL2
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    nature.com/articles/s41467-025-66007-0
  28. www.sciencedirect.com www.sciencedirect.com
    OCIAD2-IQGAP1 interaction promotes pancreatic cancer progression by suppressing oxidative stress and mitochondria-mediated apoptosis
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    sciencedirect.com/science/article/pii/S0898656825006321
  29. Oct 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12533583/
  31. Jul 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time
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    pmc.ncbi.nlm.nih.gov/articles/PMC12288891/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel defined manganese metabolism‑related gene signature for predicting the prognosis of pancreatic ductal adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12282324/
  34. www.science.org www.science.org
    Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins
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    science.org/doi/10.1126/science.adq8331
  35. May 2025
  36. www.nature.com www.nature.com
    HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity
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    nature.com/articles/s41467-025-60129-1
  37. Apr 2025
  38. www.sciencedirect.com www.sciencedirect.com
    PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124725003122
  39. Jan 2025
  40. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225001026-main-html.html
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  41. Oct 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inactivation of HIPK2 attenuates KRASG12D activity and prevents pancreatic tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11437985/
  43. Sep 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of oxidative- and endoplasmic-reticulum-stress dependent apoptosis in pancreatic cancer cell lines by DDOST knockdown
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369111/
  45. Aug 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347226/
  47. www.researchsquare.com www.researchsquare.com
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    researchsquare.com/article/rs-7072571/'https://www.researchsquare.com/article/rs-7072571/v1
  48. Apr 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BUB1 Promotes Gemcitabine Resistance in Pancreatic Cancer Cells by Inhibiting Ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11048608/
  50. Mar 2024
  51. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  52. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/47007dbc2cda4f961c79d2e8158521ca8af7c5b7/Molecular Oncology - 2023 - Bots - Preclinical evaluation of the gorilla-derived HAdV-B AdV-lumc007 oncolytic adenovirus -html.html
  53. Jan 2024
  54. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17058
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autotaxin–lysolipid signaling suppresses a CCL11–eosinophil axis to promote pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10899115/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10756117/
  57. Oct 2023
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10549224/
  59. May 2023
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
  61. Apr 2023
  62. www.science.org www.science.org
    An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation
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    science.org/doi/10.1126/sciadv.adf8966
  63. Jan 2023
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel B7-H6–Targeted IgG-Like T Cell–Engaging Antibody for the Treatment of Gastrointestinal Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9713360/
  65. www.nature.com www.nature.com
    NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer
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    nature.com/articles/s41419-022-05535-9
  66. Dec 2022
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9737747/
  68. Sep 2022
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437572/
  70. Feb 2022
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC and MIZ1-dependent vesicular transport of double-strand RNA controls immune evasion in pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7611539/
  72. Jan 2022
  73. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
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    sciencedirect.com/science/article/pii/S2211124721017459
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hyaluronic acid fuels pancreatic cancer cell growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC8730721/
  75. Nov 2021
  76. www.sciencedirect.com www.sciencedirect.com
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    sciencedirect.com/science/article/pii/S2211124721015424
  77. www.sciencedirect.com www.sciencedirect.com
    A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer
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    sciencedirect.com/science/article/pii/S004520682100883X
  78. Oct 2021
  79. www.nature.com www.nature.com
    Analysis of clonogenic growth in vitro
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    nature.com/articles/s41596-021-00615-0
  80. Jun 2021
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Gain-of-Function p53 R248W Mutant Promotes Migration by STAT3 Deregulation in Human Pancreatic Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8226097/
  82. Apr 2021
  83. www.sciencedirect.com www.sciencedirect.com
    Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
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    sciencedirect.com/science/article/pii/S0092867420313222
  84. Oct 2020
  85. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer
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    pubmed.ncbi.nlm.nih.gov/33027658/
  86. Sep 2020
  87. www.sciencedirect.com www.sciencedirect.com
    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
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    sciencedirect.com/science/article/pii/S0092867420302701
  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33137
  89. link.springer.com link.springer.com
    Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
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    link.springer.com/article/10.1186/s40170-019-0202-2
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS
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    ncbi.nlm.nih.gov/pmc/articles/PMC6952431/
  91. www.mdpi.com www.mdpi.com
    Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells
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    mdpi.com/2072-6694/12/6/1643
  92. Jan 2020
  93. www.nature.com www.nature.com
    Untitled document
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    nature.com/articles/s41388-019-0810-x
  94. Nov 2017
  95. www.sciencedirect.com www.sciencedirect.com
    Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
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    sciencedirect.com/science/article/pii/S109727651730312X