111 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
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    1. scibot 18 Dec 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.cell.2024.11.007

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    sciencedirect.com/science/article/pii/S0092867424013242
  3. Dec 2024
  4. www.sciencedirect.com www.sciencedirect.com
    lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing
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    1. scibot 02 Dec 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.molcel.2024.10.036

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    sciencedirect.com/science/article/pii/S1097276524008761
  5. www.sciencedirect.com www.sciencedirect.com
    ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis
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    1. scibot 02 Dec 2024
      CVCL_2119

      DOI: 10.1016/j.celrep.2024.114988

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    sciencedirect.com/science/article/pii/S2211124724013391
  6. Oct 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
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    1. scibot 05 Oct 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.chembiol.2023.06.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC11426993/
  8. www.sciencedirect.com www.sciencedirect.com
    Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance
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    1. scibot 02 Oct 2024
      CVCL_2119

      DOI: 10.1016/j.stem.2024.09.008

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    sciencedirect.com/science/article/pii/S1934590924003229
  9. Sep 2024
  10. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 27 Sep 2024
      RRID:CVCL_2119

      DOI: 10.1111/febs.17245

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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17245
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SJPedPanel: A pan-cancer gene panel for childhood malignancies to enhance cancer monitoring and early detection
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    1. scibot 25 Sep 2024
      RRID:CVCL_2119

      DOI: 10.1158/1078-0432.CCR-24-1063

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    ncbi.nlm.nih.gov/pmc/articles/PMC11393547/
  12. aacrjournals.org aacrjournals.org
    Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer
    1
    1. scibot 12 Sep 2024
      RRID:CVCL_2119

      DOI: 10.1158/0008-5472.CAN-21-2072

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    aacrjournals.org/cancerres/article/82/14/2538/706949/Chromatin-Rewiring-by-Mismatch-Repair-Protein-MSH2
  13. Aug 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Isolation, expansion, and adoptive transfer of human ILC2s for the treatment of mice bearing liquid and solid tumors
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    1. scibot 19 Aug 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.xpro.2024.103096

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    sciencedirect.com/science/article/pii/S2666166724002612
  15. www.cell.com www.cell.com
    SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
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    1. scibot 18 Aug 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.celrep.2024.114536

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    cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
  16. 52.53.155.43 52.53.155.43
    Downregulation of RCN1 promotes pyroptosis in acute myeloid leukemia cells
    1
    1. scibot 02 Aug 2024
      RRID: CVCL_2119

      DOI: 10.1002/1878-0261.13521

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    52.53.155.43/17d9d464af1d04aab32a8e6f8ff8e2dac32e6481/Molecular Oncology - 2023 - Deng-html.html
  17. Jul 2024
  18. www.nature.com www.nature.com
    Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
    1
    1. scibot 19 Jul 2024
      RRID: CVCL_2119

      DOI: 10.1038/s41375-024-02328-1

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      Curator: @dhovakimyan1

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  19. 52.53.155.43 52.53.155.43
    cir-23-0692-html.html
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    1. scibot 18 Jul 2024
      RRID:CVCL_2119

      DOI: 10.1158/2326-6066.cir-23-0692

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  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
    1
    1. scibot 17 Jul 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.xcrm.2024.101645

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    ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vitro CAR-T cell killing: validation of the potency assay
    1
    1. scibot 06 Jul 2024
      RRID:CVCL_2119

      DOI: 10.1007/s00262-024-03753-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11219661/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells
    1
    1. scibot 05 Jul 2024
      RRID:CVCL_2119

      DOI: 10.1158/2326-6066.CIR-23-0692

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    ncbi.nlm.nih.gov/pmc/articles/PMC11217734/
  23. Jun 2024
  24. link.springer.com link.springer.com
    β-Carboline derivatives are potent against Acute Myeloid Leukemia in vitro and in vivo
    1
    1. scibot 28 Jun 2024
      RRID:CVCL_2119

      DOI: 10.1007/s43440-024-00614-4

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    link.springer.com/article/10.1007/s43440-024-00614-4
  25. May 2024
  26. 52.53.155.43 52.53.155.43
    mct-23-0528-html.html
    1
    1. scibot 23 May 2024
      RRID:CVCL_2119

      DOI: 10.1158/1535-7163.mct-23-0528

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      Curator: @abever99

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      RRID:CVCL_2119 DOI:10.1158/1535-7163.mct-23-0528
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    52.53.155.43/aad67d20ed53c6e2e8d83cb86f88142e832868b0/mct-23-0528-html.html
  27. www.sciencedirect.com www.sciencedirect.com
    CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
    1
    1. scibot 16 May 2024
      ACC 554

      DOI: 10.1016/j.xcrm.2024.101572

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    sciencedirect.com/science/article/pii/S2666379124002647
  28. elifesciences.org elifesciences.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
    1
    1. scibot 03 May 2024
      RRID:CVCL_2119

      DOI: 10.7554/eLife.90683

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    elifesciences.org/articles/90683
  29. 52.53.155.43 52.53.155.43
    cir-23-0692-html.html
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    1. scibot 03 May 2024
      RRID:CVCL_2119

      DOI: 10.1158/2326-6066.cir-23-0692

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    52.53.155.43/8d70f9939fff89111dad79803b7a3daaa5083861/cir-23-0692-html.html
  30. Apr 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
    1
    1. scibot 26 Apr 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2024.04.004

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    sciencedirect.com/science/article/pii/S1535610824001284
  32. Mar 2024
  33. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 27 Mar 2024
      RRID:CVCL_2119

      DOI: 10.1002/1878-0261.13638

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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13638
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
    1
    1. scibot 19 Mar 2024
      RRID: CVCL_2119

      DOI: 10.1158/0008-5472.CAN-23-1534

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    ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
  35. Feb 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity
    1
    1. scibot 13 Feb 2024
      DSMZCat#ACC 554

      DOI: 10.1016/j.xcrm.2024.101422

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    sciencedirect.com/science/article/pii/S2666379124000454
  37. www.biorxiv.org www.biorxiv.org
    BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor
    1
    1. scibot 04 Feb 2024
      RRID:CVCL_2119

      DOI: 10.1101/2023.09.28.560054

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    biorxiv.org/content/10.1101/2023.09.28.560054v1
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
    1
    1. scibot 03 Feb 2024
      RRID:CVCL_2119

      DOI: 10.1158/0008-5472.CAN-23-1632

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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  39. Jan 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ULK2 Is a Key Pro-Autophagy Protein That Contributes to the High Chemoresistance and Disease Relapse in FLT3-Mutated Acute Myeloid Leukemia
    1
    1. scibot 12 Jan 2024
      CVCL_2119

      DOI: 10.3390/ijms25010646

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    ncbi.nlm.nih.gov/pmc/articles/PMC10780038/
  41. www.sciencedirect.com www.sciencedirect.com
    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
    1
    1. scibot 11 Jan 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.cell.2023.12.015

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    sciencedirect.com/science/article/pii/S0092867423013478
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developing a mechanistic translational PK/PD model for a trifunctional NK cell engager to predict the first‐in‐human dose for acute myeloid leukemia
    1
    1. scibot 11 Jan 2024
      CVCL_2119

      DOI: 10.1111/cts.13689

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    ncbi.nlm.nih.gov/pmc/articles/PMC10772472/
  43. Dec 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
    1
    1. scibot 17 Dec 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.celrep.2023.113560

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    sciencedirect.com/science/article/pii/S2211124723015723
  45. www.biorxiv.org www.biorxiv.org
    MYC–NFATC2 axis maintains cell cycle and mitochondrial function in AML cells
    1
    1. scibot 01 Dec 2023
      CVCL_2119

      DOI: 10.1101/2023.11.15.567209

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      Curator: @jmitrevska

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    biorxiv.org/content/10.1101/2023.11.15.567209v1
  46. Sep 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
    1
    1. scibot 16 Sep 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.celrep.2023.113098

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    sciencedirect.com/science/article/pii/S2211124723011099
  48. www.sciencedirect.com www.sciencedirect.com
    PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy
    1
    1. scibot 08 Sep 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.xcrm.2023.101191

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    sciencedirect.com/science/article/pii/S2666379123003580
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MET and FGFR in Relapsed or Refractory Acute Myeloid Leukemia: Preclinical and Clinical Findings, and Signal Transduction Correlates
    1
    1. scibot 07 Sep 2023
      RRID CVCL_2119

      DOI: 10.1158/1078-0432.CCR-22-2540

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC9992000/
  50. Aug 2023
  51. www.biorxiv.org www.biorxiv.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
    1
    1. scibot 16 Aug 2023
      RRID: CVCL_2119

      DOI: 10.1101/2023.07.26.550648

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      Curator: @evieth

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    biorxiv.org/content/10.1101/2023.07.26.550648v2
  52. Jul 2023
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Evidence of an Allogeneic Dual CD20xCD22 CAR to Target a Broad Spectrum of Patients with B-cell Malignancies
    1
    1. scibot 08 Jul 2023
      RRID:CVCL_2119

      DOI: 10.1158/2326-6066.CIR-22-0910

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    ncbi.nlm.nih.gov/pmc/articles/PMC10320475/
  54. Jun 2023
  55. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    1. scibot 24 Jun 2023
      RRID:CVCL_2119

      DOI: 10.1038/s41467-023-39241-7

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    nature.com/articles/s41467-023-39241-7
  56. May 2023
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
    1
    1. scibot 10 May 2023
      RRID:CVCL_2119

      DOI: 10.1002/advs.202206098

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    onlinelibrary.wiley.com/doi/10.1002/advs.202206098
  58. Apr 2023
  59. www.nature.com www.nature.com
    Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1
    1
    1. scibot 18 Apr 2023
      RRID:CVCL_2119

      DOI: 10.1038/s41408-023-00826-6

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    nature.com/articles/s41408-023-00826-6
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
    1
    1. scibot 12 Apr 2023
      RRID:CVCL_2119

      DOI: 10.1158/0008-5472.CAN-22-2129

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    ncbi.nlm.nih.gov/pmc/articles/PMC10071820/
  61. Mar 2023
  62. www.sciencedirect.com www.sciencedirect.com
    m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis
    1
    1. scibot 23 Mar 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.molcel.2023.02.024

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    sciencedirect.com/science/article/pii/S109727652300151X
  63. www.sciencedirect.com www.sciencedirect.com
    Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells
    1
    1. scibot 11 Mar 2023
      CVCL_2119

      DOI: 10.1016/j.xcrm.2023.100962

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    sciencedirect.com/science/article/pii/S266637912300054X
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
    1
    1. scibot 10 Mar 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2023.02.010

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    ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
  65. www.sciencedirect.com www.sciencedirect.com
    A bispecific T cell engager recruits both type 1 NKT and Vγ9Vδ2-T cells for the treatment of CD1d-expressing hematological malignancies
    1
    1. scibot 03 Mar 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.xcrm.2023.100961

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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical evaluation of CD70-specific CAR T cells targeting acute myeloid leukemia
    2
    1. scibot 02 Mar 2023
      RRID: CVCL_2119

      DOI: 10.3389/fimmu.2023.1093750

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      RRID:CVCL_2119

      DOI: 10.3389/fimmu.2023.1093750

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    ncbi.nlm.nih.gov/pmc/articles/PMC9950117/
  67. Feb 2023
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptionally imprinted glycomic signatures of acute myeloid leukemia
    1
    1. scibot 17 Feb 2023
      RRID:CVCL_2119

      DOI: 10.1186/s13578-023-00981-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC9926860/
  69. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD
    1
    1. scibot 17 Feb 2023
      RRID: CVCL_2119

      DOI: 10.1002/1878-0261.13368

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13368
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
    1
    1. scibot 09 Feb 2023
      CVCL_2119

      DOI: 10.1158/2643-3230.BCD-21-0160

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    ncbi.nlm.nih.gov/pmc/articles/PMC9780084/
  71. Jan 2023
  72. www.sciencedirect.com www.sciencedirect.com
    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
    1
    1. scibot 28 Jan 2023
      RRID: CVCL_2119

      DOI: 10.1016/j.stem.2022.12.003

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    sciencedirect.com/science/article/pii/S1934590922004878
  73. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways
    1
    1. scibot 14 Jan 2023
      RRID:CVCL_2119

      DOI: 10.1111/bph.15986

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15986
  74. www.sciencedirect.com www.sciencedirect.com
    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
    1
    1. scibot 06 Jan 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.stem.2022.12.006

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    sciencedirect.com/science/article/pii/S1934590922004908
  75. Dec 2022
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-tumor effect of antibody drug conjugate ASP1235 targeting Fms-like tyrosine kinase 3 with venetoclax plus azacitidine in an acute myeloid leukemia xenograft mouse model
    1
    1. scibot 31 Dec 2022
      RRID:CVCL_2119

      DOI: 10.18632/oncotarget.28331

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    ncbi.nlm.nih.gov/pmc/articles/PMC9765856/
  77. Nov 2022
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation
    1
    1. scibot 18 Nov 2022
      RRID:CVCL_2119

      DOI: 10.7554/eLife.79940

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    ncbi.nlm.nih.gov/pmc/articles/PMC9645811/
  79. Oct 2022
  80. www.cell.com www.cell.com
    The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
    1
    1. scibot 28 Oct 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2022.10.004

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    cell.com/cancer-cell/fulltext/S1535-6108(22)00495-0
  81. Sep 2022
  82. www.sciencedirect.com www.sciencedirect.com
    Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
    1
    1. scibot 30 Sep 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2022.09.007

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    sciencedirect.com/science/article/pii/S1535610822004366
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance
    1
    1. scibot 10 Sep 2022
      CVCL_2119

      DOI: 10.1155/2022/2813938

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    ncbi.nlm.nih.gov/pmc/articles/PMC9448541/
  84. www.hindawi.com www.hindawi.com
    Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance
    1
    1. scibot 07 Sep 2022
      CVCL_2119

      DOI: 10.1155/2022/2813938

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    hindawi.com/journals/jo/2022/2813938/
  85. Jun 2022
  86. 52.53.155.43 52.53.155.43
    can-21-2072-html.html
    1
    1. scibot 30 Jun 2022
      RRID:CVCL_2119

      DOI: 10.1158/0008-5472.can-21-2072

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    52.53.155.43/170847d59a031feb550122423bcef303df6c67ab/can-21-2072-html.html
  87. aacrjournals.org aacrjournals.org
    Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
    1
    1. scibot 18 Jun 2022
      RRID:CVCL_2119

      DOI: 10.1158/0008-5472.CAN-21-0548

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    aacrjournals.org/cancerres/article/82/11/2141/699099/Phosphorylation-of-SHP2-at-Tyr62-Enables-Acquired
  88. May 2022
  89. www.tandfonline.com www.tandfonline.com
    JMJD1C-regulated lipid synthesis contributes to the maintenance of MLL-rearranged acute myeloid leukemia
    1
    1. scibot 11 May 2022
      RRID:CVCL_2119

      DOI: 10.1080/10428194.2022.2068004

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    tandfonline.com/doi/abs/10.1080/10428194.2022.2068004
  90. Apr 2022
  91. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
    1
    1. scibot 21 Apr 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.cell.2022.03.030

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    sciencedirect.com/science/article/pii/S0092867422003403
  92. Mar 2022
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDK6 Degradation Is Counteracted by p16INK4A and p18INK4C in AML
    1
    1. scibot 26 Mar 2022
      RRID:CVCL_2119

      DOI: 10.3390/cancers14061554

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    ncbi.nlm.nih.gov/pmc/articles/PMC8946512/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
    1
    1. scibot 18 Mar 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.isci.2022.103985

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    ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
  95. www.sciencedirect.com www.sciencedirect.com
    The proteogenomic subtypes of acute myeloid leukemia
    1
    1. scibot 04 Mar 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2022.02.006

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    sciencedirect.com/science/article/pii/S1535610822000587
  96. www.sciencedirect.com www.sciencedirect.com
    MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
    1
    1. scibot 04 Mar 2022
      DSMZACC 554

      DOI: 10.1016/j.molcel.2022.02.013

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    sciencedirect.com/science/article/pii/S1097276522001186
  97. Feb 2022
  98. www.sciencedirect.com www.sciencedirect.com
    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
    1
    1. scibot 18 Feb 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.molcel.2022.01.014

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    sciencedirect.com/science/article/pii/S1097276522000570
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Overcoming tumor heterogeneity by ex vivo arming of T cells using multiple bispecific antibodies
    2
    1. scibot 11 Feb 2022
      RRID:CVCL_2119

      DOI: 10.1136/jitc-2021-003771

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      RRID:CVCL_2119

      DOI: 10.1136/jitc-2021-003771

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    ncbi.nlm.nih.gov/pmc/articles/PMC8796264/
  100. www.sciencedirect.com www.sciencedirect.com
    Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML
    1
    1. scibot 02 Feb 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.tranon.2022.101354

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    sciencedirect.com/science/article/pii/S193652332200016X
  101. Jan 2022
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)
    1
    1. scibot 15 Jan 2022
      RRID:CVCL_2119

      DOI: 10.1038/s41408-021-00603-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC8752621/
  103. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    1
    1. scibot 12 Jan 2022
      ACC 554

      DOI: 10.1016/j.celrep.2021.110233

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    sciencedirect.com/science/article/pii/S2211124721017423
  104. Sep 2021
  105. www.sciencedirect.com www.sciencedirect.com
    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
    1
    1. scibot 23 Sep 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.molcel.2021.08.033

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    sciencedirect.com/science/article/pii/S1097276521007139
  106. www.sciencedirect.com www.sciencedirect.com
    A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
    1
    1. scibot 01 Sep 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.chembiol.2021.08.004

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    sciencedirect.com/science/article/pii/S2451945621003937
  107. Aug 2021
  108. www.sciencedirect.com www.sciencedirect.com
    Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
    1
    1. scibot 12 Aug 2021
      CVCL_2119

      DOI: 10.1016/j.cmet.2019.01.011

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    sciencedirect.com/science/article/pii/S1550413119300117
  109. www.sciencedirect.com www.sciencedirect.com
    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
    1
    1. scibot 07 Aug 2021
      ACC-554

      DOI: 10.1016/j.molcel.2021.07.018

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    sciencedirect.com/science/article/pii/S1097276521005876
  110. link.springer.com link.springer.com
    The BET bromodomain inhibitor ZEN-3365 targets the Hedgehog signaling pathway in acute myeloid leukemia
    1
    1. scibot 04 Aug 2021
      RRID:CVCL_2119

      DOI: 10.1007/s00277-021-04602-z

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    link.springer.com/article/10.1007/s00277-021-04602-z
  111. Jul 2021
  112. www.sciencedirect.com www.sciencedirect.com
    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
    1
    1. scibot 31 Jul 2021
      Human: MOLM-13

      DOI: 10.1016/j.ccell.2019.10.002

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    sciencedirect.com/science/article/pii/S1535610819304763
  113. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 30 Jul 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.chembiol.2018.11.006

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    sciencedirect.com/science/article/pii/S2451945618304136
  114. www.sciencedirect.com www.sciencedirect.com
    Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
    1
    1. scibot 28 Jul 2021
      RRID: CVCL_2119

      DOI: 10.1016/j.cmet.2019.01.011

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    sciencedirect.com/science/article/pii/S1550413119300117
  115. www.sciencedirect.com www.sciencedirect.com
    ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia
    1
    1. scibot 27 Jul 2021
      ACC-554

      DOI: 10.1016/j.ccell.2018.02.002

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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    sciencedirect.com/science/article/pii/S1535610818300230
  116. Jun 2021
  117. www.sciencedirect.com www.sciencedirect.com
    MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway
    1
    1. scibot 23 Jun 2021
      CVCL_2119

      DOI: 10.1016/j.ebiom.2021.103441

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    sciencedirect.com/science/article/pii/S2352396421002346
  118. jitc.bmj.com jitc.bmj.com
    T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemia
    1
    1. scibot 12 Jun 2021
      RRID:CVCL_2119

      DOI: 10.1136/jitc-2021-002509

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    jitc.bmj.com/content/9/5/e002509
  119. May 2021
  120. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
    1
    1. scibot 18 May 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.cell.2021.04.022

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    sciencedirect.com/science/article/pii/S009286742100502X
  121. www.sciencedirect.com www.sciencedirect.com
    Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
    1
    1. scibot 12 May 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.celrep.2021.109101

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    sciencedirect.com/science/article/pii/S2211124721004356
  122. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Targeting DNA damage repair functions of two histone deacetylases, HDAC8 and SIRT6, sensitizes acute myeloid leukemia to NAMPT inhibition
    1
    1. scibot 10 May 2021
      RRID:CVCL_2119

      DOI: 10.1158/1078-0432.CCR-20-3724

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    clincancerres.aacrjournals.org/content/27/8/2352
  123. www.sciencedirect.com www.sciencedirect.com
    CRISPR screens in physiologic medium reveal conditionally essential genes in human cells
    1
    1. scibot 01 May 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.cmet.2021.02.005

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    sciencedirect.com/science/article/pii/S1550413121000619
  124. Apr 2021
  125. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
    1
    1. scibot 22 Apr 2021
      ACC 554

      DOI: 10.1016/j.ccell.2020.10.010

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S1535610820305419
  126. www.sciencedirect.com www.sciencedirect.com
    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
    1
    1. scibot 19 Apr 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.molcel.2021.02.012

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    sciencedirect.com/science/article/pii/S1097276521000988
  127. www.sciencedirect.com www.sciencedirect.com
    Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia
    1
    1. scibot 17 Apr 2021
      ACC 554

      DOI: 10.1016/j.ccell.2020.05.014

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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    sciencedirect.com/science/article/pii/S1535610820302646
  128. www.sciencedirect.com www.sciencedirect.com
    Immunogenomic Landscape of Hematological Malignancies
    1
    1. scibot 17 Apr 2021
      CVCL_2119

      DOI: 10.1016/j.ccell.2020.06.002

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S1535610820302750
  129. Mar 2021
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
    1
    1. scibot 02 Mar 2021
      RRID:CVCL_2119

      DOI: 10.7554/eLife.65905

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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    ncbi.nlm.nih.gov/pmc/articles/PMC7886351/
  131. Sep 2020
  132. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 25 Sep 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2019.12.002

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S1535610819305720
  133. www.nature.com www.nature.com
    High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening
    1
    1. scibot 23 Sep 2020
      CVCL_2119

      DOI: 10.1038/s41467-020-17209-1

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @evieth

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    nature.com/articles/s41467-020-17209-1
  134. www.sciencedirect.com www.sciencedirect.com
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
    1
    1. scibot 16 Sep 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.celrep.2020.107840

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S2211124720308214
  135. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells
    1
    1. scibot 06 Sep 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.stem.2020.03.016

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1934590920301387
  136. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-mediated Apoptosis.
    1
    1. scibot 04 Sep 2020
      CVCL_2119

      DOI: 10.1158/1078-0432.CCR-19-1900

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @evieth

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    clincancerres.aacrjournals.org/content/26/13/3371
  137. www.sciencedirect.com www.sciencedirect.com
    Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2
    1
    1. scibot 04 Sep 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.cell.2020.03.051

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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    sciencedirect.com/science/article/pii/S0092867420303445
  138. www.sciencedirect.com www.sciencedirect.com
    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
    1
    1. scibot 04 Sep 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.stem.2020.04.001

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1934590920301405
  139. www.sciencedirect.com www.sciencedirect.com
    RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia
    1
    1. scibot 04 Sep 2020
      RRID: CVCL_2119

      DOI: 10.1016/j.stem.2020.04.009

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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    sciencedirect.com/science/article/pii/S193459092030148X
  140. www.sciencedirect.com www.sciencedirect.com
    Highly Parallel Quantification and Compartment Localization of Transcription Factors and Nuclear Proteins
    1
    1. scibot 03 Sep 2020
      MOLM13

      DOI: 10.1016/j.celrep.2020.01.096

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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      RRID:CVCL_2119 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124720301303
  141. Aug 2020
  142. www.nature.com www.nature.com
    High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening
    1
    1. scibot 23 Aug 2020
      RRID:CVCL_2119

      DOI: 10.1038/s41467-020-17209-1

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @evieth

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    nature.com/articles/s41467-020-17209-1
  143. Jan 2020
  144. www.sciencedirect.com www.sciencedirect.com
    HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2019.10.011

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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    sciencedirect.com/science/article/pii/S1535610819304854
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_2119

      DOI: 10.1038/s41408-018-0165-5

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
  146. Nov 2018
  147. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_2119

      Curator: @Jmenke

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      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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      RRID:CVCL_2119 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610818300126
  148. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_2119

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      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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      RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S1535610817305020
  149. www.sciencedirect.com www.sciencedirect.com
    Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_2119

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      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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      RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S1535610817305159
  150. Nov 2017
  151. www.sciencedirect.com www.sciencedirect.com
    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
    1
    1. scibot 08 Nov 2017
      ACC 554

      Curator: @Jmenke

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      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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      RRID:CVCL_2119 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610817303641
  152. www.sciencedirect.com www.sciencedirect.com
    Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia
    1
    1. scibot 08 Nov 2017
      MOLM13

      Curator: @kaitlinsung

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      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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    sciencedirect.com/science/article/pii/S0092867416316853
  153. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
    1
    1. scibot 08 Nov 2017
      ACC 554

      Curator: @gabimpine

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      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

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      RRID:CVCL_2119 RRIDCUR:Missing
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    pmc.ncbi.nlm.nih.gov/articles/PMC7360335/