Hypothesis

35 Matching Annotations

May 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225008454-main-html.html

1
1. scibot 18 May 2025
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1016/j.isci.2025.112584
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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52.53.155.43/2f59eea255f6dfa2798e1e0fcb3d7e10d3ba6bc8/1-s2.0-S2589004225008454-main-html.html
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Downregulation of rRNA synthesis by BCL-2 induces chemoresistance in diffuse large B cell lymphoma

1
1. scibot 24 Apr 2025
  
  in Public
  
  ACC 572
  
  DOI: 10.1016/j.isci.2025.112333
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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sciencedirect.com/science/article/pii/S2589004225005942
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The FBXO45–GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis

1
1. scibot 04 Apr 2025
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1158/2159-8290.CD-24-0442
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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pmc.ncbi.nlm.nih.gov/articles/PMC11962402/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy

1
1. scibot 18 Mar 2025
  
  in Public
  
  RRID: CVCL_2206
  
  DOI: 10.3389/fimmu.2025.1518787
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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pmc.ncbi.nlm.nih.gov/articles/PMC11897230/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway

1
1. scibot 13 Mar 2025
  
  in Public
  
  CVCL_2206
  
  DOI: 10.21203/rs.3.rs-6017610/v1
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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pmc.ncbi.nlm.nih.gov/articles/PMC11875301/
Feb 2025
aacrjournals.org aacrjournals.org

Repurposing NAMPT inhibitors for germinal center B-cell-like diffuse large B-cell lymphoma

1
1. scibot 20 Feb 2025
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1158/2643-3230.BCD-24-0020
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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URL

aacrjournals.org/bloodcancerdiscov/article/5/6/417/749227/Repurposing-NAMPT-Inhibitors-for-Germinal-Center-B
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

GNAS knockout potentiates HDAC3 inhibition through viral mimicry-related interferon responses in lymphoma

1
1. scibot 02 Oct 2024
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1038/s41375-024-02325-4
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC11436380/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma

1
1. scibot 05 Sep 2024
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1158/1535-7163.MCT-23-0299
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10932871/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of bromodomain and extra-terminal proteins targets constitutively active NFκB and STAT signaling in lymphoma and influences the expression of the antiapoptotic proteins BCL2A1 and c-MYC

1
1. scibot 29 Aug 2024
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1186/s12964-024-01782-9
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11348570/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma

1
1. scibot 24 Jul 2024
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1016/j.ccell.2024.05.026
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S1535610824002174
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects

1
1. scibot 24 May 2024
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1158/2767-9764.CRC-24-0071
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11110724/
www.sciencedirect.com www.sciencedirect.com

Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas

1
1. scibot 03 May 2024
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1016/j.ccell.2024.04.007
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S1535610824001314
Jun 2023
www.nature.com www.nature.com

Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

1
1. scibot 24 Jun 2023
  
  in Public
  
  RRID: CVCL_2206
  
  DOI: 10.1038/s41467-023-39241-7
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

nature.com/articles/s41467-023-39241-7
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer

1
1. scibot 04 May 2023
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1158/1078-0432.CCR-22-0669
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9633392/
Apr 2023
aacrjournals.org aacrjournals.org

IOA-244 is a Non–ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance

1
1. scibot 19 Apr 2023
  
  in Public
  
  CVCL_2206
  
  DOI: 10.1158/2767-9764.CRC-22-0477
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

aacrjournals.org/cancerrescommun/article/3/4/576/725855/IOA-244-is-a-Non-ATP-competitive-Highly-Selective
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2-dependent glutaminolysis pathway

1
1. scibot 26 Oct 2022
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1126/sciadv.abq0117
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9524954/
www.science.org www.science.org

Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2–dependent glutaminolysis pathway

1
1. scibot 22 Oct 2022
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1126/sciadv.abq0117
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

science.org/doi/10.1126/sciadv.abq0117
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis

1
1. scibot 21 Apr 2022
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1016/j.cell.2022.03.030
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S0092867422003403
Nov 2021
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 17 Nov 2021
  
  in Public
  
  CVCL_2206
  
  DOI: 10.1002/1878-0261.13115
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2206
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_2206
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RRIDCUR:Missing

RRID:CVCL_2206

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scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13115
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

1
1. scibot 31 Jul 2021
  
  in Public
  
  SUDHL6
  
  DOI: 10.1016/j.celrep.2019.10.083
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719314056
www.sciencedirect.com www.sciencedirect.com

MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells

1
1. scibot 31 Jul 2021
  
  in Public
  
  SUDHL6
  
  DOI: 10.1016/j.celrep.2019.09.040
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719312288
www.sciencedirect.com www.sciencedirect.com

Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

1
1. scibot 30 Jul 2021
  
  in Public
  
  SU-DHL-6
  
  DOI: 10.1016/j.ccell.2019.08.005
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2206
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_2206
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RRIDCUR:Missing

RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819303733
www.sciencedirect.com www.sciencedirect.com

Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling

1
1. scibot 30 Jul 2021
  
  in Public
  
  SU-DHL-6
  
  DOI: 10.1016/j.chembiol.2019.07.010
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2206
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_2206
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RRIDCUR:Missing

RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S2451945619302417
www.sciencedirect.com www.sciencedirect.com

ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors

1
1. scibot 22 Jul 2021
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1016/j.xcrm.2021.100350
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S2666379121001993
Jun 2021
www.nature.com www.nature.com

Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia

1
1. scibot 17 Jun 2021
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1038/s41467-021-23752-2
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

nature.com/articles/s41467-021-23752-2
May 2021
www.sciencedirect.com www.sciencedirect.com

Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas

1
1. scibot 07 May 2021
  
  in Public
  
  CVCL_2206
  
  DOI: 10.1016/j.immuni.2020.11.002
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S1074761320304672
Feb 2021
www.sciencedirect.com www.sciencedirect.com

Targeted reduction of cholesterol uptake in cholesterol-addicted lymphoma cells blocks turnover of oxidized lipids to cause ferroptosis

1
1. scibot 27 Feb 2021
  
  in Public
  
  CVCL_2206
  
  DOI: 10.1074/jbc.RA120.014888
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S0021925820000903
cancerres.aacrjournals.org cancerres.aacrjournals.org

3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1158/0008-5472.CAN-20-1822
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2206
  
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  RRID:CVCL_2206
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RRID:CVCL_2206

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scibot

URL

cancerres.aacrjournals.org/content/81/4/847
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Combination Treatment with GSK126 and Pomalidomide Induces B-Cell Differentiation in EZH2 Gain-of-Function Mutant Diffuse Large B-Cell Lymphoma

1
1. scibot 15 Sep 2020
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.3390/cancers12092541
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2206
  
  What is this?
  
  RRID:CVCL_2206 RRIDCUR:Validated
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RRID:CVCL_2206

RRIDCUR:Validated

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scibot

URL

pubmed.ncbi.nlm.nih.gov/32906688/
www.sciencedirect.com www.sciencedirect.com

Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

1
1. scibot 08 Sep 2020
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1016/j.celrep.2020.107840
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2206
  
  What is this?
  
  RRID:CVCL_2206 RRIDCUR:Validated
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RRID:CVCL_2206

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720308214
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

IKKε and TBK1 in diffuse large B‐cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF‐κB and IL‐10 signalling

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1111/jcmm.15774
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2206
  
  What is this?
  
  RRID:CVCL_2206 RRIDCUR:Validated
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RRID:CVCL_2206

RRIDCUR:Validated

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scibot

URL

pubmed.ncbi.nlm.nih.gov/32858764/
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.7554/eLife.50036
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2206
  
  What is this?
  
  RRID:CVCL_2206 RRIDCUR:Validated
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RRID:CVCL_2206

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6897534/
www.sciencedirect.com www.sciencedirect.com

Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1016/j.cmet.2019.09.009
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2206
  
  What is this?
  
  RRID:CVCL_2206 RRIDCUR:Validated
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RRID:CVCL_2206

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1550413119305121
www.sciencedirect.com www.sciencedirect.com

LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_2206
  
  DOI: 10.1016/j.ccell.2019.07.007
  
  Resource: (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2206
  
  What is this?
  
  RRID:CVCL_2206 RRIDCUR:Validated
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RRID:CVCL_2206

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819303344
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  SU-DHL-6
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (ATCC Cat# CRL-2959, RRID:CVCL_2206)
  
  SciCrunch record: RRID:CVCL_2206
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_2206 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_2206

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scibot

URL

sciencedirect.com/science/article/pii/S0092867416316853