Hypothesis

19 Matching Annotations

Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Integrative proteogenomics and forward genetics reveals a novel mitotic vulnerability in triple-negative breast cancer

1
1. scibot 26 Nov 2025
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1158/2159-8290.CD-23-1173
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3383
  
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  RRID:CVCL_3383
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RRID:CVCL_3383

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12641601/
Sep 2025
www.sciencedirect.com www.sciencedirect.com

PDE7A inhibition suppresses triple-negative breast cancer by attenuating de novo pyrimidine biosynthesis

1
1. scibot 17 Sep 2025
  
  in Public
  
  ATCC CRL-4010
  
  DOI: 10.1016/j.xcrm.2025.102356
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383
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RRID:CVCL_3383

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scibot

URL

sciencedirect.com/science/article/pii/S266637912500429X
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tissue-dependent mechanosensing by cells derived from human tumors

1
1. scibot 12 Aug 2025
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1038/s44341-025-00023-5
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383
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RRID:CVCL_3383

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression

1
1. scibot 05 Aug 2025
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1158/0008-5472.CAN-24-4774
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383
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RRID:CVCL_3383

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival

1
1. scibot 27 Feb 2025
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1038/s44319-024-00361-w
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383
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RRID:CVCL_3383

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11850729/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Breast cancer cells utilize T3 to trigger proliferation through cellular Ca2+ modulation

1
1. scibot 10 Nov 2024
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1186/s12964-024-01917-y
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383
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RRID:CVCL_3383

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11539297/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy

1
1. scibot 21 Aug 2024
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1158/2767-9764.CRC-24-0077
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383
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RRID:CVCL_3383

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11310748/
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization

1
1. scibot 21 May 2023
  
  in Public
  
  ATCC CRL-4010
  
  DOI: 10.7554/eLife.85167
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383
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RRID:CVCL_3383

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10191626/
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index

1
1. scibot 12 Jan 2023
  
  in Public
  
  CVCL_3383
  
  DOI: 10.1158/1535-7163.MCT-21-0518
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383
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RRID:CVCL_3383

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9377749/
Jul 2022
www.sciencedirect.com www.sciencedirect.com

Data Driven and Biophysical Insights into the Regulation of Trafficking Vesicles by Extracellular Matrix Stiffness

1
1. scibot 27 Jul 2022
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1016/j.isci.2022.104721
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383
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RRID:CVCL_3383

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scibot

URL

sciencedirect.com/science/article/pii/S2589004222009932
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC-overexpressing triple-negative breast cancer

1
1. scibot 15 Sep 2021
  
  in Public
  
  CRL-4010
  
  DOI: 10.1016/j.chembiol.2021.08.011
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_3383
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RRIDCUR:Missing

RRID:CVCL_3383

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scibot

URL

sciencedirect.com/science/article/pii/S2451945621004001
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

1
1. scibot 01 Aug 2021
  
  in Public
  
  CVCL_3383
  
  DOI: 10.1016/j.cels.2019.11.001
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_3383

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scibot

URL

sciencedirect.com/science/article/pii/S2405471219303874
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Chromatin Remodeling in Response to BRCA2-Crisis

1
1. scibot 29 Jul 2021
  
  in Public
  
  hTert-HME1
  
  DOI: 10.1016/j.celrep.2019.07.057
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_3383

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719309611
www.sciencedirect.com www.sciencedirect.com

HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding

1
1. scibot 29 Jul 2021
  
  in Public
  
  hTert-HME1
  
  DOI: 10.1016/j.molcel.2019.05.034
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_3383

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S109727651930406X
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Prolonged mitosis causes separase deregulation and chromosome nondisjunction

1
1. scibot 20 Jan 2021
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1016/j.celrep.2020.108652
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_3383

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720316417
Oct 2020
www.cell.com www.cell.com

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

1
1. scibot 18 Oct 2020
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1016/j.chembiol.2020.07.011
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_3383

Annotators

scibot

URL

cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1016/j.chembiol.2019.05.005
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_3383

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945619301746
www.sciencedirect.com www.sciencedirect.com

HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1016/j.molcel.2019.05.034
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:CVCL_3383

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S109727651930406X
www.sciencedirect.com www.sciencedirect.com

Chromatin Remodeling in Response to BRCA2-Crisis

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_3383
  
  DOI: 10.1016/j.celrep.2019.07.057
  
  Resource: (ATCC Cat# CRL-4010, RRID:CVCL_3383)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_3383
  
  What is this?
  
  RRID:CVCL_3383 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:CVCL_3383

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719309611