100 Matching Annotations
  1. Last 7 days
  2. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    The VCPIP1-UBE3A Deubiquitination-Ubiquitination Cascade Contributes to Castration-Resistant Prostate Cancer Progression
    1
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.78433
  3. Oct 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ERG Orchestrates a Dedifferentiation–Senescence–Inflammation Triad in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13631506/
  5. www.sciencedirect.com www.sciencedirect.com
    Box C/D SNORD116-17 promotes prostate cancer progression by targeting the miR-206/E2F5 axis
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    sciencedirect.com/science/article/pii/S2589004226031871
  6. Sep 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLPI is associated with AR-regulated epithelial adaptation and enzalutamide sensitivity in castration-resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13529726/
  8. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Castration-resistant prostate cancer cells are addicted to the high activity of cyclin-dependent kinase 2
    1
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70319
  9. Jul 2026
  10. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Butyrylated PGAM5-Triggered and GSH-Responsive Cysteine Polymer Nanoparticles for CBL0137 Delivery to Enhance Necroptosis in Prostate Cancer
    1
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/adhm.71387
  11. Jun 2026
  12. aacrjournals.org aacrjournals.org
    Prostate Cancer Cells Secrete PD-1 in Exosomes to Enhance Myeloid-Derived Suppressor Cell Activity and Promote Tumor Immune Evasion
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    aacrjournals.org/cancerres/article/85/18/3435/764454/Prostate-Cancer-Cells-Secrete-PD-1-in-Exosomes-to
  13. www.sciencedirect.com www.sciencedirect.com
    CDC20 promotes prostate cancer progression via modulating c-MYC and PI3K-AKT signaling
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    sciencedirect.com/science/article/pii/S2589004226017840
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TMPRSS2-ERG confers resistance of prostate cancer to antiandrogens
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    pmc.ncbi.nlm.nih.gov/articles/PMC13269939/
  15. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    ROS Cascade-Amplified Polymeric Nanosystem Exhibiting Multi-Pathway Induction of Immunogenic Cell Death and Chemotherapeutic Efficacy in Tumor
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.71279
  16. www.nature.com www.nature.com
    MCCC2 stabilizes LTBP1 via suppressing SMURF1-dependent ubiquitination to drive bone metastasis in prostate cancer
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    nature.com/articles/s41388-026-03843-4
  17. May 2026
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impaired vitamin D signaling reveals neutrophils as key drivers of prostate cancer dissemination
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    pmc.ncbi.nlm.nih.gov/articles/PMC13179334/
  19. Apr 2026
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    hsa-circKLK3-25 promotes epithelial-mesenchymal transition and malignant progression of prostate cancer through the JNK/ERK signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13090479/
  21. www.sciencedirect.com www.sciencedirect.com
    Astragaloside IV directly targets PPP1R14B to sensitize prostate cancer to anti-PD-1 immunotherapy by remodeling the CX3CL1/CD8+ T cell axis
    1
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    sciencedirect.com/science/article/pii/S0944711326003922
  22. Mar 2026
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting FANCD2 to overcome enzalutamide resistance in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12997758/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KDM5B-driven glucose metabolic reprogramming promotes enzalutamide resistance in prostate cancer via the lactate/hnRNPA1 lactylation/AR-V7 axis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12980947/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    OGDHL promotes prostate cancer progression and regulates neuroendocrine marker expression and nucleotide abundance
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12949684/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phytochemical Profiling of the Halophyte Artemisia fukudo Makino and Its In Vitro Effects on Androgen‐Related Pathways Associated With Benign Prostatic Hyperplasia and Alopecia
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12949454/
  27. Feb 2026
  28. www.nature.com www.nature.com
    Epigenetic regulation of NDGA and its synergistic inhibition with EZH2 inhibitors in prostate cancer via NRP1
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    nature.com/articles/s41401-026-01754-4
  29. www.nature.com www.nature.com
    The FOSB-IGFBP5-IGF-1 axis: a novel regulatory pathway that suppresses prostate cancer growth
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    nature.com/articles/s41417-026-01012-z
  30. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro-Metastatic N-Glycosylation and Predict Prostate Cancer Progression
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202522885
  31. Dec 2025
  32. www.tandfonline.com www.tandfonline.com
    A novel biochip-based liquid biopsy for extracellular vesicle RNA detection in prostate cancer
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    tandfonline.com/doi/full/10.1080/15384047.2025.2593744
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    tRF-21LeuTAA Promotes Oxidative Stress by Altering Glutathione Metabolic Enzymes to Support Prostate Cancer Progression
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666318/
  34. Nov 2025
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Off-pore nucleoporin sPOM121 transcriptionally propels β-Catenin driven tumor progression and immune escape in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12580793/
  36. Oct 2025
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mechanistic Insights Into METTL1/WDR4-Mediated m7G Modification in Prostate Cancer Progression and Its Potential as a Therapeutic Target
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    onlinelibrary.wiley.com/doi/10.1002/jbt.70546
  38. Sep 2025
  39. www.nature.com www.nature.com
    Induction of ferroptosis in prostate cancer by CCDC719-13 via TRIM21-mediated ubiquitination of SLC7A11
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    nature.com/articles/s41418-025-01580-x
  40. www.sciencedirect.com www.sciencedirect.com
    A smart gene circuit for precise regulation of tumor cell behavior
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    sciencedirect.com/science/article/pii/S2405805X25001577
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    c-MYC mRNA destabilization inhibited lethal pancreatic cancer in vivo with significant survival outcomes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12426058/
  42. www.sciencedirect.com www.sciencedirect.com
    Disrupting the interaction between androgen receptor and its coregulator WDR77 delays the growth of treatment-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S221112472501006X
  43. Aug 2025
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC12358827/
  45. www.biorxiv.org www.biorxiv.org
    Exploration of oncogenic cooperation between germline variation and somatic mutation in prostate cancer progression
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    biorxiv.org/content/10.1101/2025.08.05.668679v1
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anticancer activity of triterpene glycosides from the sea star Solaster pacificus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322260/
  48. Jun 2025
  49. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70049
  50. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Ezetimibe Engineered L14-8 Suppresses Advanced Prostate Cancer by Activating PLK1/TP53-SAT1-Induced Ferroptosis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202504192
  51. www.cell.com www.cell.com
    BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways
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    cell.com/cell-reports/fulltext/S2211-1247(25)00550-9
  52. www.sciencedirect.com www.sciencedirect.com
    Cholesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S2211124725005637
  53. Apr 2025
  54. 52.53.155.43 52.53.155.43
    rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
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    52.53.155.43/fbc444166f400a01dc32894063d12537e1e236f5/rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
  55. www.sciencedirect.com www.sciencedirect.com
    Development and validation of a kinase-related gene signature as a novel diagnostic and prognostic model for prostate cancer
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    sciencedirect.com/science/article/pii/S0925443925000675
  56. Mar 2025
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Secretome Analysis of Prostate Cancer Cell Lines Reveals Cell Cycle-Dependent PSA Secretion and Potential Biomarkers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11899065/
  58. Jan 2025
  59. www.sciencedirect.com www.sciencedirect.com
    Amorphous calcium phosphate-coated surfaces as a model for bone microenvironment in prostate cancer
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    sciencedirect.com/science/article/pii/S2405844025003093
  60. Dec 2024
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining Splicing Factor Requirements for Androgen Receptor Variant Synthesis in Advanced Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11612623/
  62. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224027329-main-html.html
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    52.53.155.43/3c53ef10f625befcd704a131cd24200ff9587189/1-s2.0-S2589004224027329-main-html.html
  63. Nov 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anoikis in prostate cancer bone metastasis gene signatures and therapeutic implications
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    ncbi.nlm.nih.gov/pmc/articles/PMC11464922/
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NOSTRIN is involved in benign prostatic hyperplasia via inhibition of proliferation, oxidative stress, and inflammation in prostate epithelial cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11491235/
  66. Oct 2024
  67. www.sciencedirect.com www.sciencedirect.com
    Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition
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    sciencedirect.com/science/article/pii/S2666379124004828
  68. Sep 2024
  69. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17271
  70. www.sciencedirect.com www.sciencedirect.com
    Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610824003179
  71. Aug 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10641717/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11311709/
  74. pubs.acs.org pubs.acs.org
    Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening
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    pubs.acs.org/doi/10.1021/acs.jmedchem.2c00864
  75. Jul 2024
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating miR-6880-5p in extracellular vesicle from plasma as a prognostic biomarker in endocrine therapy-treated castration-resistant prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285227/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11261775/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identify Regulatory eQTLs by Multiome Sequencing in Prostate Single Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11213234/
  79. Apr 2024
  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Metabolic characterization of sphere-derived prostate cancer stem cells reveals aberrant urea cycle in stemness maintenance
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34967
  81. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  82. Mar 2024
  83. www.sciencedirect.com www.sciencedirect.com
    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
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    sciencedirect.com/science/article/pii/S1535610824000485
  84. Feb 2024
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879682/
  86. 52.53.155.43 52.53.155.43
    can-23-0555-html.html
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    52.53.155.43/e8db3efafb8a8253e8641e16f59e9a4a6a668dad/can-23-0555-html.html
  87. 52.53.155.43 52.53.155.43
    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
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    52.53.155.43/3b983d9532a50e2ebeba730d1190ef88722ceb9a/PIIS2589004224003468-html.html
  88. Nov 2023
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Concurrent targeting of HDAC and PI3K to overcome phenotypic heterogeneity of castration-resistant and neuroendocrine prostate cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10658857/
  90. Sep 2023
  91. www.sciencedirect.com www.sciencedirect.com
    Combined CRISPRi and proteomics screening reveal a cohesin-CTCF-bound allele contributing to increased expression of RUVBL1 and prostate cancer progression
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    sciencedirect.com/science/article/pii/S0002929723002434
  92. Aug 2023
  93. www.sciencedirect.com www.sciencedirect.com
    Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer
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    sciencedirect.com/science/article/pii/S0223523423006979
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The long transcript of lncRNA TMPO-AS1 promotes bone metastases of prostate cancer by regulating the CSNK2A1/DDX3X complex in Wnt/β-catenin signaling
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10403548/
  95. Jul 2023
  96. 52.53.155.43 52.53.155.43
    rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
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    52.53.155.43/fbc444166f400a01dc32894063d12537e1e236f5/rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Tumor Suppressor DAB2IP Is Regulated by Cell Contact and Contributes to YAP/TAZ Inhibition in Confluent Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10340159/
  98. Jun 2023
  99. www.sciencedirect.com www.sciencedirect.com
    Minor intron splicing is critical for survival of lethal prostate cancer
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    sciencedirect.com/science/article/pii/S1097276523003738
  100. Feb 2023
  101. www.science.org www.science.org
    PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition
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    science.org/doi/10.1126/sciadv.ade8641
  102. Sep 2022
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reversible epigenetic alterations regulate class I HLA loss in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437063/
  104. Aug 2022
  105. www.sciencedirect.com www.sciencedirect.com
    Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance
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    sciencedirect.com/science/article/pii/S1535610822003579
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC8349875/
  107. Jul 2022
  108. www.sciencedirect.com www.sciencedirect.com
    Data Driven and Biophysical Insights into the Regulation of Trafficking Vesicles by Extracellular Matrix Stiffness
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    sciencedirect.com/science/article/pii/S2589004222009932
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of long non-coding RNA NXTAR in prostate cancer augments androgen receptor expression and enzalutamide resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC8732311/
  110. May 2022
  111. www.sciencedirect.com www.sciencedirect.com
    The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62
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    sciencedirect.com/science/article/pii/S2211124722005599
  112. Apr 2022
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIRO2 regulates prostate cancer cell growth via GCN1-dependent stress signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8983529/
  114. Mar 2022
  115. www.sciencedirect.com www.sciencedirect.com
    The mTOR chromatin-bound interactome in prostate cancer
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    sciencedirect.com/science/article/pii/S2211124722002753
  116. Feb 2022
  117. www.sciencedirect.com www.sciencedirect.com
    Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
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    sciencedirect.com/science/article/pii/S2211124722001462
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-27/IL-27RA signaling may modulate inflammation and progression of benign prostatic hyperplasia via suppressing the LPS/TLR4 pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC8798123/
  119. Jan 2022
  120. academic.oup.com academic.oup.com
    Novel role of prostate cancer risk variant rs7247241 on PPP1R14A isoform transition through allelic TF binding and CpG methylation
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    Crosstalk of FGFR1 signaling and choline metabolism promotes cell proliferation and survival in prostate cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33922
  122. Nov 2021
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells
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    Alternative splicing of NF-YA promotes prostate cancer aggressiveness and represents a new molecular marker for clinical stratification of patients
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    link.springer.com/article/10.1186/s13046-021-02166-4
  125. Oct 2021
  126. www.sciencedirect.com www.sciencedirect.com
    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124721013371
  127. Sep 2021
  128. www.sciencedirect.com www.sciencedirect.com
    A mechanistic insight into the anti-metastatic role of the prostate specific antigen
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  129. Aug 2021
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRD9 is a critical regulator of androgen receptor signaling and prostate cancer progression
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  131. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer
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  132. May 2021
  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling
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  134. Feb 2021
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    Apocryphal FADS2 activity promotes fatty acid diversification in cancer
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  136. Nov 2020
  137. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Thyroid and androgen receptor signaling are antagonized by CRYM in prostate cancer
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  138. Sep 2020
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miR-137-3p Modulates the Progression of Prostate Cancer by Regulating the JNK3/EZH2 Axis
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  140. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Retinoic acid receptor γ is a therapeutically targetable driver of growth and survival in prostate cancer
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  142. www.sciencedirect.com www.sciencedirect.com
    Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase
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  143. Nov 2018
  144. www.sciencedirect.com www.sciencedirect.com
    Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus
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  145. Nov 2017
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    ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer
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    Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer
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