340 Matching Annotations
  1. Jan 2026
  2. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225028536-main-html.html
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    54.241.53.176/240dc6a05105efbe0d3f771207c7fadaa29f2101/1-s2.0-S2589004225028536-main-html.html
  3. Dec 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12710464/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CU Cilia – an application for image analysis by machine learning – reveals significance of cysteine cathepsin K activity for primary cilia of human thyroid epithelial cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12695601/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    D3-GPC2-directed CAR T cells are safe and efficacious in preclinical models of neuroblastoma and small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12699724/
  7. 54.241.53.176 54.241.53.176
    2025.12.02.691883.full-html.html
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  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TXNIP mediates LAT1/SLC7A5 endocytosis to limit amino acid uptake in cells entering quiescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12669767/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining the antitumor mechanism of action of a clinical-stage compound as a selective degrader of the nuclear pore complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670082/
  10. Nov 2025
  11. www.sciencedirect.com www.sciencedirect.com
    Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope
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    sciencedirect.com/science/article/pii/S1097276525008688
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    A microscopy-based CRISPR screening platform enables organellar functional genomics and illuminates ciliary biology
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    sciencedirect.com/science/article/pii/S1534580725006665
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    KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C
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    sciencedirect.com/science/article/pii/S2211124725012860
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12583604/
  15. www.cell.com www.cell.com
    Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
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    cell.com/cell/fulltext/S0092-8674(25)01178-X
  16. Oct 2025
  17. academic.oup.com academic.oup.com
    Impact of somatic XIST deletions on ongoing XIST expression and inactive X silencing and heterochromatin
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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddaf160/8300178
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    Chromatin remodeling activity of EP400 safeguards chromosomal stability by preventing CENP-A mislocalization
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    sciencedirect.com/science/article/pii/S2211124725011945
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
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    pmc.ncbi.nlm.nih.gov/articles/PMC11496028/
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    Protocol for identifying DNA damage responders through proximity biotinylation of proliferating cell nuclear antigen interactors
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    sciencedirect.com/science/article/pii/S2666166725005428
  21. Sep 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ubiquitination-activated TAB–TAK1–IKK–NF-κB axis modulates gene expression for cell survival in the lysosomal damage response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12459955/
  23. 54.241.53.176 54.241.53.176
    kakui-et-al-2025-progressive-chromosome-shape-changes-during-cell-divisions-html.html
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    Intrinsic heterogeneity of primary cilia revealed through spatial proteomics
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    sciencedirect.com/science/article/pii/S0092867425010293
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    IFT88-KAP interaction defines a conserved mechanism for kinesin-2-IFT coupling
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    sciencedirect.com/science/article/pii/S0960982225011224
  26. jbiomedsci.biomedcentral.com jbiomedsci.biomedcentral.com
    PPM1D is directly degraded by proteasomes in a ubiquitination-independent manner through its carboxyl-terminal region
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    jbiomedsci.biomedcentral.com/articles/10.1186/s12929-025-01185-z
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    Pharmacologic interrogation of USP28 cellular function in p53 signaling
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    sciencedirect.com/science/article/pii/S2451945625002326
  28. Aug 2025
  29. www.sciencedirect.com www.sciencedirect.com
    YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition
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    sciencedirect.com/science/article/pii/S2211124725009593
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    Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress
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    sciencedirect.com/science/article/pii/S1097276525006148
  31. 52.53.155.43 52.53.155.43
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    53BP1 regulates p53-E2F7-dependent transcriptional gene repression and participates in the Fanconi anemia pathway
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    sciencedirect.com/science/article/pii/S2211124725009234
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Accurate Identification of Cell Cycle Stages in RPE1 Cells Using the ImmunoCellCycle-ID Method
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    pmc.ncbi.nlm.nih.gov/articles/PMC12336857/
  34. www.tandfonline.com www.tandfonline.com
    Harnessing Lactiplantibacillus plantarum EP21 and its membrane vesicles to inhibit myopia development
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    tandfonline.com/doi/full/10.1080/19490976.2025.2534677
  35. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70201
  36. Jul 2025
  37. www.sciencedirect.com www.sciencedirect.com
    Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling
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    sciencedirect.com/science/article/pii/S2211124725008617
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    14-3-3ɛ inhibits premature centriole disengagement by inhibiting the activity of Plk1 and Separase
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    pmc.ncbi.nlm.nih.gov/articles/PMC12301659/
  39. www.biorxiv.org www.biorxiv.org
    Mitotic slippage causes nuclear instability in polyploid cells
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    biorxiv.org/content/10.1101/2025.07.21.665898v1
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    The mitotic ATR-Chk1 pathway promotes CDK1 activity for faithful chromosome segregation
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    sciencedirect.com/science/article/pii/S2211124725007909
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nanoscale 3D DNA tracing in non-denatured cells resolves the Cohesin-dependent loop architecture of the genome in situ
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    pmc.ncbi.nlm.nih.gov/articles/PMC12276220/
  42. journals.biologists.com journals.biologists.com
    Proteasome-dependent Orc6 removal from chromatin upon S-phase entry safeguards against minichromosome maintenance complex reloading and tetraploidy
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    journals.biologists.com/jcs/article/138/13/jcs263596/368530/Proteasome-dependent-Orc6-removal-from-chromatin
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    Protocol for immunostaining of non-adherent cells and cellular structures using centrifugal filter devices
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    sciencedirect.com/science/article/pii/S2666166725003405
  44. Jun 2025
  45. www.sciencedirect.com www.sciencedirect.com
    The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells
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    sciencedirect.com/science/article/pii/S1097276525005027
  46. 52.53.155.43 52.53.155.43
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  47. www.embopress.org www.embopress.org
    Transcriptional enhancers in human neuronal differentiation provide clues to neuronal disorders
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    embopress.org/doi/full/10.1038/s44319-025-00372-1
  48. www.cell.com www.cell.com
    Phase separation of TTBK2 and CEP164 is necessary for ciliogenesis
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    cell.com/cell-reports/fulltext/S2211-1247(25)00581-9
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12161472/
  50. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Germline pathogenic variants in HIC1 DNA binding domains are associated with familial serrated polyposis syndrome
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35492
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Image-based identification and isolation of micronucleated cells to dissect cellular consequences
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    pmc.ncbi.nlm.nih.gov/articles/PMC12129451/
  52. May 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion
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    pmc.ncbi.nlm.nih.gov/articles/PMC12113259/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12122001/
  55. www.nature.com www.nature.com
    Multigenerational cell tracking of DNA replication and heritable DNA damage
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    nature.com/articles/s41586-025-08986-0
  56. www.sciencedirect.com www.sciencedirect.com
    Direct Arp2/3-vinculin binding is required for pseudopod extension, but only on compliant substrates and in 3D
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    sciencedirect.com/science/article/pii/S2589004225008843
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDK4/6 activity is required during G2 arrest to prevent stress induced endoreplication
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    pmc.ncbi.nlm.nih.gov/articles/PMC11305671/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapy-induced senescence of glioblastoma cells is determined by the p21CIP1-CDK1/2 axis and does not require activation of DREAM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12049523/
  59. www.sciencedirect.com www.sciencedirect.com
    OSMOTIC STRESS INFLUENCES MICROTUBULE DRUG RESPONSE VIA WNK1 KINASE SIGNALING
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    sciencedirect.com/science/article/pii/S1368764625000032
  60. Apr 2025
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway–Deficient Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12011380/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NF-κB signaling directs a program of transient amplifications at innate immune response genes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952383/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage
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    pmc.ncbi.nlm.nih.gov/articles/PMC12081312/
  64. www.nature.com www.nature.com
    Supra-second tracking and live-cell karyotyping reveal principles of mitotic chromosome dynamics
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    nature.com/articles/s41556-025-01637-6
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225006248-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12053632/
  66. Mar 2025
  67. www.sciencedirect.com www.sciencedirect.com
    Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers
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    sciencedirect.com/science/article/pii/S0304383525002319
  68. 52.53.155.43 52.53.155.43
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  69. www.embopress.org www.embopress.org
    Transcriptional enhancers in human neuronal differentiation provide clues to neuronal disorders
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    embopress.org/doi/full/10.1038/s44319-025-00372-1
  70. www.sciencedirect.com www.sciencedirect.com
    The pro-inflammatory cytokine IL6 suppresses mitochondrial function via the gp130-JAK1/STAT1/3-HIF1α/ERRα axis
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    sciencedirect.com/science/article/pii/S2211124725001743
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape
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    pmc.ncbi.nlm.nih.gov/articles/PMC11832170/
  72. Feb 2025
  73. 52.53.155.43 52.53.155.43
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  74. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70019
  75. elifesciences.org elifesciences.org
    Oversized cells activate global proteasome-mediated protein degradation to maintain cell size homeostasis
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    elifesciences.org/articles/75393
  76. aacrjournals.org aacrjournals.org
    Targeting GPC2 on intraocular and CNS metastatic retinoblastomas with local and systemic delivery of CAR T-cells
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    aacrjournals.org/clincancerres/article/30/16/3578/746772/Targeting-GPC2-on-Intraocular-and-CNS-Metastatic
  77. www.sciencedirect.com www.sciencedirect.com
    The homologous recombination factors BRCA2 and PALB2 interplay with mismatch repair pathways to maintain centromere stability and cell viability
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    sciencedirect.com/science/article/pii/S2211124725000300
  78. Jan 2025
  79. elifesciences.org elifesciences.org
    PEBP1 amplifies mitochondrial dysfunction-induced integrated stress response
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    elifesciences.org/articles/102852
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement
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    pmc.ncbi.nlm.nih.gov/articles/PMC11385174/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell Type Specific Suppression of Hyper-Recombination by Human RAD18 Is Linked to Proliferating Cell Nuclear Antigen K164 Ubiquitination
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    pmc.ncbi.nlm.nih.gov/articles/PMC11763143/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiome Perturb-seq unlocks scalable discovery of integrated perturbation effects on the transcriptome and epigenome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11738662/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint
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    pmc.ncbi.nlm.nih.gov/articles/PMC11735390/
  84. www.sciencedirect.com www.sciencedirect.com
    mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase
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    sciencedirect.com/science/article/pii/S2211124724015304
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    Phosphorylation of Ephexin4 at Ser-41 contributes to chromosome alignment via RhoG activation in cell division
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    sciencedirect.com/science/article/pii/S0021925824025869
  86. www.sciencedirect.com www.sciencedirect.com
    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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    sciencedirect.com/science/article/pii/S1074761324005685
  87. Dec 2024
  88. 52.53.155.43 52.53.155.43
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  89. www.cell.com www.cell.com
    The histone H3.3 K27M mutation suppresses Ser31phosphorylation and mitotic fidelity, which can directly drive gliomagenesis
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    cell.com/current-biology/abstract/S0960-9822(24)01575-6
  90. elifesciences.org elifesciences.org
    PEBP1 amplifies mitochondrial dysfunction induced integrated stress response
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    elifesciences.org/reviewed-preprints/102852
  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC11621922/
  92. www.sciencedirect.com www.sciencedirect.com
    Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation
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    sciencedirect.com/science/article/pii/S2211124724013433
  93. Nov 2024
  94. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11574021/
  95. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inter-chromosomal contacts demarcate genome topology along a spatial gradient
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    pmc.ncbi.nlm.nih.gov/articles/PMC11557711/
  96. www.sciencedirect.com www.sciencedirect.com
    Acute multi-level response to defective de novo chromatin assembly in S-phase
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    sciencedirect.com/science/article/pii/S1097276524008633
  97. www.sciencedirect.com www.sciencedirect.com
    Rab11-Rab8 cascade dynamics in primary cilia and membrane tubules
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    sciencedirect.com/science/article/pii/S2211124724013068
  98. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Time-resolved proximity proteomics uncovers a membrane tension-sensitive caveolin-1 interactome at the rear of migrating cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11509677/
  99. Oct 2024
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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