92 Matching Annotations
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    Cornuside regulates P2X7r-NLRP3 signaling pathway through the E3 ubiquitin ligase NEDD4 to improve radiation-induced liver fibrosis
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    sciencedirect.com/science/article/pii/S094471132601130X
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    TDQ-Cl ameliorates hepatic fibrosis-associated inflammation and intestinal injury through regulating RXRα-STAT3 signaling
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    sciencedirect.com/science/article/pii/S156757692601475X
  4. Sep 2026
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    Vitamin E treatment modulates steatotic and attenuates oxidative stress in a MASLD in vitro model
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    PXDN knockdown alleviates hepatic stellate cell activation by regulating GPX1
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    sciencedirect.com/science/article/pii/S0925443926003182
  7. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    S100 Calcium-Binding Protein 16 (S100A16) Promotes Hepatic Stellate Cell Activation Via Erb-B2 Receptor Tyrosine Kinase 2 (ERBB2)-mediated Glycolysis to Facilitate Liver Fibrosis
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  8. Aug 2026
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    Development of a matrix-supported 2.5-dimensional co-culture model: an in vitro platform for studying liver cell interaction and disease mechanisms
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    Human placenta extract declines fat deposition in an in vitro novel 3D MASLD model
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    A trifluoromethyl quinazoline inhibits hepatocellular carcinoma proliferation through HDAC1 binding and multi-target mechanisms
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  12. Jul 2026
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    GDF15 Reprograms the Microenvironment to Drive Liver Metastasis of Uveal Melanoma
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    Targeting p21-High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
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    Serum SOS1 as a prognostic biomarker and therapeutic target for progressive liver disease
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    Sex Hormone-Binding Globulin Prevents Carbon Tetrachloride-Induced Liver Fibrosis Development
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    Rosavin mitigates hepatic fibrosis via KLF14-mediated suppression of P2X7 receptor-dependent inflammatory signaling cascades
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  19. May 2026
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    Hepatic stellate cell-specific METTL3 deficiency promotes hepatocellular carcinoma progression via BMP10-SMAD1/5/8 signaling
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    Curcumin Targets Crispld2 to Suppress Hepatic Stellate Cell Activation via PI3K/AKT Pathway Inhibition in Hepatic Fibrosis
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    AI-driven network pharmacology and multi-omics validation identify KCNH2 as a prognostic biomarker and candidate therapeutic vulnerability of Acorus tatarinowii in glioblastoma
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    Deficient chaperone-mediated autophagy drives multiorgan fibrogenesis via SMAD2/4 stabilization to sustain TGFβ-SMAD signaling
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    Asarinin alleviates hepatic fibrosis through TRα-STAT3 pathway: A new strategy by regulating liver microenvironment
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  26. Apr 2026
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    UPLC-MS/MS-Network Pharmacology and Experimental Validation Reveal Active Components of Ficus tikoua for Ameliorating Liver Fibrosis
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    Deubiquitinase USP2 promotes hepatic stellate cell activation via p300 stabilization
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  31. Mar 2026
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    ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment
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    Global molecular landscape of early MASLD progression in human obesity
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  34. Feb 2026
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    Lack of PCK1 in hepatic stellate cells causes liver fibrosis by fueling tricarboxylic acid cycle and increasing glycolysis
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    Inhibitory effect of Anwulignan on the IL-36R/TLR9 signaling pathway: potential therapeutic role in hepatic fibrosis
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  37. Jan 2026
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    Curcumol Induces Necroptosis of Hepatic Stellate Cells by Targeting KAT8 to Suppress HK2 Lactylation and Promote HUWE1-Dependent Ubiquitination
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    Genetic Insights into the Economic Toll of Cell Line Misidentification: A Comprehensive Review
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  40. Dec 2025
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    CADD-engineered peptide protacs efficiently target PCSK9 for hypercholesterolemia in vivo
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    Reprogramming offspring liver health: maternal indole supplementation as a preventive strategy against MASLD
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  44. Oct 2025
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    Syringin attenuates fibrogenesis and inflammation through SIRT3-regulated P2X7 receptor signaling pathway in hepatic fibrosis
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    Liver-Targeted Scutellarin Nanoemulsion Alleviates Fibrosis with Ancillary Modulation of the Gut–Liver Microbiota
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    Prorenin in Hepatic Stellate Cell Extracellular Vesicles Induces Platelet‐Dependent Thrombin Formation and Release of Profibrotic TGF‐β
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  49. Sep 2025
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    Comprehensive Genetic and Molecular Characterization Confirms Hepatic Stellate Cell Origin of the Immortal Col-GFP HSC Line
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  51. Jun 2025
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    Calycosin limits hepatic fibrogenesis via KLF15 dependent repression of P2X7R in thioacetamide-induced hepatic fibrosis
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  53. May 2025
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    Engineering a three-dimensional liver steatosis model
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  55. Apr 2025
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    A Novel Mechanism of the p53 Isoform Δ40p53α in Regulating Collagen III Expression in TGFβ1-Induced LX-2 Human Hepatic Stellate Cells
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  57. Jan 2025
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    Pemigatinib suppresses liver fibrosis and subsequent osteodystrophy in mice
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  59. Nov 2024
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    Raspberry Ketone Attenuates Hepatic Fibrogenesis and Inflammation via Regulating the Crosstalk of FXR and PGC-1α Signaling
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    Eriocitrin ameliorates hepatic fibrosis and inflammation: The involvement of PPARα-mediated NLRP1/NLRC4 inflammasome signaling cascades
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  62. Aug 2024
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    GSK805 inhibits alpha-smooth muscle expression and modulates liver inflammation without impairing the well-being of mice
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    Raspberry Ketone Attenuates Hepatic Fibrogenesis and Inflammation via Regulating the Crosstalk of FXR and PGC-1α Signaling
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  65. Jul 2024
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    Identification and characterization of TM4SF1+ tumor self-seeded cells
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  67. Jun 2024
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    Gossypetin targets the liver-brain axis to alleviate pre-existing liver fibrosis and hippocampal neuroinflammation in mice
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    Nicotine aggravates liver fibrosis via α7 nicotinic acetylcholine receptor expressed on activated hepatic stellate cells in mice
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  70. May 2024
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  72. Apr 2024
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    Albiflorin ameliorates thioacetamide-induced hepatic fibrosis: The involvement of NURR1-mediated inflammatory signaling cascades in hepatic stellate cells activation
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    The antiprotozoal drug nitazoxanide improves experimental liver fibrosis in mice
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    Virological response to nucleos(t)ide analogues treatment in chronic hepatitis B patients is associated with Bacteroides-dominant gut microbiome
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  76. Feb 2024
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    p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
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  78. Jan 2024
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    Schizandrin C regulates lipid metabolism and inflammation in liver fibrosis by NF-κB and p38/ERK MAPK signaling pathways
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    IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids
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    Intranasal Delivery of Oncolytic Adenovirus XVir-N-31 via Optimized Shuttle Cells Significantly Extends Survival of Glioblastoma-Bearing Mice
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    Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation
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  83. Nov 2023
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    Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases
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  85. Oct 2023
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    Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage
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    Polyenylphosphatidylcholines as bioactive excipient in tablets for the treatment of liver fibrosis
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  89. Sep 2023
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  91. Jul 2023
  92. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation
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  93. Jan 2023
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  95. Dec 2022
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    Physcion alleviates chronic alcoholic hepatic inflammation and pyroptosis through SIRT1-AMPK activation
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  97. Nov 2022
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    STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.
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    MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2 Associated Cell Adhesion
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  100. Sep 2022
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    Salvianolic acid B suppresses hepatic stellate cell activation and liver fibrosis by inhibiting the NF-κB signaling pathway via miR-6499-3p/LncRNA-ROR
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  102. Jul 2022
  103. www.nature.com www.nature.com
    Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis
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    Antiproliferative and Antimicrobial Effects of Rosmarinus officinalis L. Loaded Liposomes
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  105. Jun 2022
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  107. Mar 2022
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer
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    The in vitro and in vivo study of a pyrazole derivative, J-1063, as a novel anti-liver fibrosis agent: Synthesis, biological evaluation, and mechanistic analysis
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    A novel HSF1 activator ameliorates nonalcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation
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    Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus
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  112. Dec 2021
  113. cancerimmunolres.aacrjournals.org cancerimmunolres.aacrjournals.org
    The Fibronectin–ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells
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    Liver sphingomyelin synthase 1 deficiency causes steatosis, steatohepatitis, fibrosis, and tumorigenesis: An effect of glucosylceramide accumulation
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  115. Sep 2021
  116. www.mdpi.com www.mdpi.com
    Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect
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  117. Aug 2021
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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