378 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Downregulation of PIEZO1 activity promotes breast cancer cell survival under shear stress by modulating β-catenin and BCL2
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    pmc.ncbi.nlm.nih.gov/articles/PMC13329331/
  3. Jul 2026
  4. www.nature.com www.nature.com
    Inducing physiological polarity and performing gene editing using CRISPR–Cas9 in human trophoblast organoids
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    nature.com/articles/s41596-026-01402-5
  5. Jun 2026
  6. aacrjournals.org aacrjournals.org
    ZC3H13 Loss Drives Cancer Metastatic Progression by Disrupting m6A RNA Methylation
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    aacrjournals.org/cancerres/article/86/3/622/771927/ZC3H13-Loss-Drives-Cancer-Metastatic-Progression
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    Pooled combinatorial screening identifies transcription factor sets that drive hematopoietic progenitor-like cell fate
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    sciencedirect.com/science/article/pii/S2405471226001262
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DGAT1 Drives Racially Divergent Fibroblast Activation via ERK1/2-Dependent Tumorigenic Signaling in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13234498/
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    Enhancing platinum-based chemotherapy efficacy and safety through combination therapy-mediated remodeling of autophagic homeostasis in gastric cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13234414/
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    Development of far-red fluorescent proteins for temporal domain multiplexing and super-resolution imaging
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    sciencedirect.com/science/article/pii/S2667237526001712
  11. May 2026
  12. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70365
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13126711/
  14. Apr 2026
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    Acyltransferase ZDHHC22 promotes N-Myc transcriptional activation to drive neuroblastoma progression and chemoresistance
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    sciencedirect.com/science/article/pii/S1097276526002364
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    CCDC80 suppresses high-grade serous ovarian cancer migration via negative regulation of B7-H3
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70235
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13089303/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TDP43 and hnRNP K Regulate Alternative Splicing of DNAJC5
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    pmc.ncbi.nlm.nih.gov/articles/PMC13081507/
  19. 54.241.53.176 54.241.53.176
    2026.04.04.716465.full-html.html
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    Development of human monoclonal antibodies against TARM1 by yeast display
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.70216
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70342
  22. 54.241.53.176 54.241.53.176
    Oncogenic virus hijacks SOX18 pioneer function to enhance viral persistence
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    Macropinocytosis and Vascularization Determine Response to mTOR Inhibitors in Lung Squamous Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12774322/
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    Sensing and perturbing mammalian cell states with reprogrammable ADAR sensors (RADARS)
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    nature.com/articles/s41596-025-01305-x
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture
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  26. Mar 2026
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    Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126000777
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    ORMDL Proteins Turnover via Proteasome and Autophagy Is Cell‐Type Dependent and Tied to Ceramide Homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12974560/
  29. www.biorxiv.org www.biorxiv.org
    The Alternative Polyadenylation Factor CFIm25 Orchestrates Macrophage Antibacterial Immunity by Amplifying TAB2-Mediated MAPK and NF-κB Signaling During Salmonella Infection
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    biorxiv.org/content/10.64898/2026.02.26.707986v1
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    Matrix Metalloproteinase‐13 Is an Unfavorable Prognostic Factor in Chordoma by Digesting Growth Inhibitory Collagens
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    onlinelibrary.wiley.com/doi/10.1002/cam4.71662
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    Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia
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  32. Feb 2026
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MIG-6 Regulates HDAC1-Mediated Angiogenesis and Tumorigenesis in PTEN-Deficient Endometrioid Endometrial Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12935093/
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    GCAD: A Computational Framework for Mammalian Genetic Program Computer-Aided Design
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    sciencedirect.com/org/science/article/pii/S2161506326000549
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    Matrix Metalloproteinase‐13 Is an Unfavorable Prognostic Factor in Chordoma by Digesting Growth Inhibitory Collagens
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    onlinelibrary.wiley.com/doi/10.1002/cam4.71662
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    Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126000303
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic targeting of YOD1 disrupts the PAX-FOXO1-N-Myc feedback loop in rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12892920/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12900515/
  39. 54.241.53.176 54.241.53.176
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  40. Jan 2026
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    Axes of biological variation in diffuse large B cell lymphoma
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    Afatinib exerts an inhibitory effect on T cell-mediated cytotoxicity
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    link.springer.com/article/10.1007/s00262-025-04279-7
  43. elifesciences.org elifesciences.org
    Nonlinear transcriptional responses to gradual modulation of transcription factor dosage
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    elifesciences.org/articles/100555
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    Crosstalk between the ribosome quality control-associated E3 ubiquitin ligases LTN1 and RNF10
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.70230
  45. Dec 2025
  46. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Oxidized MIF is an Alzheimer’s disease drug target relaying external risk factors to tau pathology
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  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency
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    pmc.ncbi.nlm.nih.gov/articles/PMC12717831/
  48. www.nature.com www.nature.com
    MDC1 counteracts replication fork reversal and mediates chemosensitivity in BRCA1/2-deficient tumors
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  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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  50. www.biorxiv.org www.biorxiv.org
    DYRK1A regulates cancer cell and cancer-associated fibroblast secretomes to foster an immunosuppressive microenvironment in pancreatic cancer
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    biorxiv.org/content/10.1101/2025.11.26.690756v1
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA
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  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges during Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666315/
  53. Nov 2025
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma
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  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhanced cleavage of genomic CCR5 using CASX2Max
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  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Claudin-4 as a dual regulator of genome stability and immune evasion in high grade serous ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12603150/
  57. 54.241.53.176 54.241.53.176
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  58. www.embopress.org www.embopress.org
    Inhibiting cholesterol synthesis halts rhabdomyosarcoma growth via ER stress and cell cycle arrest
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    embopress.org/doi/10.1038/s44321-025-00336-x
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs
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  60. www.sciencedirect.com www.sciencedirect.com
    Radiation-induced glioblastoma stem cell-mediated T cell exhaustion via EGR1-Gal3-LAG3 axis in glioblastoma
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    sciencedirect.com/science/article/pii/S0304383525006974
  61. Oct 2025
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    Proximity interactome mapping furthers a role for spinophilin in protein homeostasis
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    Identification of molecular markers and exploration of the oncogenic role of exomeres in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2211124725012318
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    GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer
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    biorxiv.org/content/10.1101/2025.10.17.682994v1
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma
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    Lipid-regulated phosphorylation hierarchy of the T cell receptor tyrosine motifs
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  67. Sep 2025
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CA-125 as a Biomarker in Renal Medullary Carcinoma: Integrated Molecular Profiling, Functional Characterization, and Prospective Clinical Validation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11913570/
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    Structural insights into DdCBE in action enable high-precision mitochondrial DNA editing
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    The tumor suppressor CYLD acts as a deubiquitinase for mTOR to constrain its activity
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    biorxiv.org/content/10.1101/2025.09.01.673523v1
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    UBE2T promotes epithelial-mesenchymal transition and motility in oral cancer cells via induction of IL-6 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12365892/
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    PKN2 is a dependency of the mesenchymal-like cancer cell state
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  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1 Mutant Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12221223/pdf/can-24-3904.pdf
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    A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer
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    GCAD: a Computational Framework for Mammalian Genetic Program Computer-Aided Design
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    pmc.ncbi.nlm.nih.gov/articles/PMC12393561/
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    Conversion of natural cytokine receptors into orthogonal synthetic biosensors
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  77. www.nature.com www.nature.com
    Evaluating CAR-T cells from neurofibromatosis type 1 (NF1) patients for targeting AXL in malignant peripheral nerve sheath tumors associated with NF1
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  78. 52.53.155.43 52.53.155.43
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    Distinct interaction modes orchestrate the polymerization of ASC PYD and CARD domains into filamentous structures
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    K29-Linked Ubiquitination of Transcription Regulators Controls Cell Proliferation in the Unfolded Protein Response
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202509817
  81. Aug 2025
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    Fibroblast bioelectric signaling drives hair growth
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  83. www.biorxiv.org www.biorxiv.org
    Exploration of oncogenic cooperation between germline variation and somatic mutation in prostate cancer progression
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    biorxiv.org/content/10.1101/2025.08.05.668679v1
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ENHANCED CLEAVAGE OF GENOMIC CCR5 USING CASX2Max
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    pmc.ncbi.nlm.nih.gov/articles/PMC12265720/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated real-time imaging of executioner caspase dynamics, apoptosis-induced proliferation, and immunogenic cell death using a stable fluorescent reporter platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328661/
  86. www.cell.com www.cell.com
    Systematic screening for functional exon-skipping isoforms using the CRISPR-RfxCas13d system
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    cell.com/cell-systems/fulltext/S2405-4712(25)00184-X
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    Enhanced bioluminescence imaging of tumor cells surviving chemotherapy in a murine model of triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12311029/
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structure and mechanism of the RalGAP tumor suppressor complex
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  89. Jul 2025
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Triglycerides are an important fuel reserve for synapse function in the brain
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  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12277487/
  92. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Massively parallel in vivo Perturb-seq screening
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  93. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
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  94. Jun 2025
  95. www.sciencedirect.com www.sciencedirect.com
    A bedside-to-bench translational analysis of NF1 alterations and CDK4/6 inhibitor resistance in hormone receptor-positive metastatic breast cancer
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    sciencedirect.com/science/article/pii/S2352396425002725
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70097
  97. www.cell.com www.cell.com
    Phase separation of TTBK2 and CEP164 is necessary for ciliogenesis
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    cell.com/cell-reports/fulltext/S2211-1247(25)00581-9
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    RalGAP complexes control secretion and primary cilia in pancreatic disease
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  198. Mar 2024
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