388 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Local, but not circulating, complement C3 shapes immune checkpoint blockade efficacy by controlling myeloid cell infiltration
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    pmc.ncbi.nlm.nih.gov/articles/PMC13490386/
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    hnRNP A1 controls MIR17HG alternative splicing and maturation of miR-19a
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    pmc.ncbi.nlm.nih.gov/articles/PMC13468856/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The alternative polyadenylation factor CFIm25 orchestrates macrophage antibacterial activity against Salmonella through the TAB2 and TBL1XR1 regulators of MAPK and NF-κB signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13460137/
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    HERC4 synergizes with USP16 to promote lung adenocarcinoma growth by augmenting protein translation via stabilizing RPS15
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    nature.com/articles/s41388-026-03902-w
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    Trans-regulatory gene mapping prioritizes disease drivers in asthma
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    sciencedirect.com/science/article/pii/S0092867426008664
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
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    pmc.ncbi.nlm.nih.gov/articles/PMC13405622/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HER2 heterogeneous breast cancer models reveal novel therapeutic targets and subclonal dynamics during evolution to resistance to HER2-targeted therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430225/
  10. Jul 2026
  11. journals.asm.org journals.asm.org
    The alternative polyadenylation factor CFIm25 orchestrates macrophage antibacterial activity against Salmonella through the TAB2 and TBL1XR1 regulators of MAPK and NF-κB signaling
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    journals.asm.org/doi/10.1128/iai.00361-26
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    Large-scale genome structure interrogation via recombinase-mediated rearrangements of multiplexed prime edits in repetitive elements
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    nature.com/articles/s41596-026-01409-y
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor-derived complement C3 overexpression in STK11-mutant lung adenocarcinoma drives tumor growth and immune checkpoint inhibitor resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC13348722/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Downregulation of PIEZO1 activity promotes breast cancer cell survival under shear stress by modulating β-catenin and BCL2
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    pmc.ncbi.nlm.nih.gov/articles/PMC13329331/
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    Inducing physiological polarity and performing gene editing using CRISPR–Cas9 in human trophoblast organoids
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    nature.com/articles/s41596-026-01402-5
  16. Jun 2026
  17. aacrjournals.org aacrjournals.org
    ZC3H13 Loss Drives Cancer Metastatic Progression by Disrupting m6A RNA Methylation
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    aacrjournals.org/cancerres/article/86/3/622/771927/ZC3H13-Loss-Drives-Cancer-Metastatic-Progression
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    Pooled combinatorial screening identifies transcription factor sets that drive hematopoietic progenitor-like cell fate
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    sciencedirect.com/science/article/pii/S2405471226001262
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DGAT1 Drives Racially Divergent Fibroblast Activation via ERK1/2-Dependent Tumorigenic Signaling in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13234498/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing platinum-based chemotherapy efficacy and safety through combination therapy-mediated remodeling of autophagic homeostasis in gastric cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13234414/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of far-red fluorescent proteins for temporal domain multiplexing and super-resolution imaging
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    pmc.ncbi.nlm.nih.gov/articles/PMC13390083/
  22. May 2026
  23. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70365
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13126711/
  25. Apr 2026
  26. www.sciencedirect.com www.sciencedirect.com
    Acyltransferase ZDHHC22 promotes N-Myc transcriptional activation to drive neuroblastoma progression and chemoresistance
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    sciencedirect.com/science/article/pii/S1097276526002364
  27. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CCDC80 suppresses high-grade serous ovarian cancer migration via negative regulation of B7-H3
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70235
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13089303/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TDP43 and hnRNP K Regulate Alternative Splicing of DNAJC5
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    pmc.ncbi.nlm.nih.gov/articles/PMC13081507/
  30. 54.241.53.176 54.241.53.176
    2026.04.04.716465.full-html.html
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    Development of human monoclonal antibodies against TARM1 by yeast display
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.70216
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70342
  33. 54.241.53.176 54.241.53.176
    Oncogenic virus hijacks SOX18 pioneer function to enhance viral persistence
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  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Macropinocytosis and Vascularization Determine Response to mTOR Inhibitors in Lung Squamous Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12774322/
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    Sensing and perturbing mammalian cell states with reprogrammable ADAR sensors (RADARS)
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    nature.com/articles/s41596-025-01305-x
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture
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  37. Mar 2026
  38. www.sciencedirect.com www.sciencedirect.com
    Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126000777
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ORMDL Proteins Turnover via Proteasome and Autophagy Is Cell‐Type Dependent and Tied to Ceramide Homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12974560/
  40. www.biorxiv.org www.biorxiv.org
    The Alternative Polyadenylation Factor CFIm25 Orchestrates Macrophage Antibacterial Immunity by Amplifying TAB2-Mediated MAPK and NF-κB Signaling During Salmonella Infection
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    biorxiv.org/content/10.64898/2026.02.26.707986v1
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    Matrix Metalloproteinase‐13 Is an Unfavorable Prognostic Factor in Chordoma by Digesting Growth Inhibitory Collagens
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    onlinelibrary.wiley.com/doi/10.1002/cam4.71662
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    Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12936425/
  43. Feb 2026
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MIG-6 Regulates HDAC1-Mediated Angiogenesis and Tumorigenesis in PTEN-Deficient Endometrioid Endometrial Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12935093/
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    GCAD: A Computational Framework for Mammalian Genetic Program Computer-Aided Design
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    sciencedirect.com/org/science/article/pii/S2161506326000549
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    Matrix Metalloproteinase‐13 Is an Unfavorable Prognostic Factor in Chordoma by Digesting Growth Inhibitory Collagens
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    onlinelibrary.wiley.com/doi/10.1002/cam4.71662
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    Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126000303
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic targeting of YOD1 disrupts the PAX-FOXO1-N-Myc feedback loop in rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12892920/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12900515/
  50. 54.241.53.176 54.241.53.176
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  51. Jan 2026
  52. www.sciencedirect.com www.sciencedirect.com
    Axes of biological variation in diffuse large B cell lymphoma
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    sciencedirect.com/science/article/pii/S1535610825005495
  53. link.springer.com link.springer.com
    Afatinib exerts an inhibitory effect on T cell-mediated cytotoxicity
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    link.springer.com/article/10.1007/s00262-025-04279-7
  54. elifesciences.org elifesciences.org
    Nonlinear transcriptional responses to gradual modulation of transcription factor dosage
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    elifesciences.org/articles/100555
  55. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Crosstalk between the ribosome quality control-associated E3 ubiquitin ligases LTN1 and RNF10
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.70230
  56. Dec 2025
  57. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Oxidized MIF is an Alzheimer’s disease drug target relaying external risk factors to tau pathology
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  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency
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    pmc.ncbi.nlm.nih.gov/articles/PMC12717831/
  59. www.nature.com www.nature.com
    MDC1 counteracts replication fork reversal and mediates chemosensitivity in BRCA1/2-deficient tumors
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    nature.com/articles/s41388-025-03659-8
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12710464/
  61. www.biorxiv.org www.biorxiv.org
    DYRK1A regulates cancer cell and cancer-associated fibroblast secretomes to foster an immunosuppressive microenvironment in pancreatic cancer
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    biorxiv.org/content/10.1101/2025.11.26.690756v1
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA
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    pmc.ncbi.nlm.nih.gov/articles/PMC12709618/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges during Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666315/
  64. Nov 2025
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma
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  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhanced cleavage of genomic CCR5 using CASX2Max
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  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Claudin-4 as a dual regulator of genome stability and immune evasion in high grade serous ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12603150/
  68. 54.241.53.176 54.241.53.176
    2025.11.15.688645v1.full-html.html
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    Inhibiting cholesterol synthesis halts rhabdomyosarcoma growth via ER stress and cell cycle arrest
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    embopress.org/doi/10.1038/s44321-025-00336-x
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs
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    Radiation-induced glioblastoma stem cell-mediated T cell exhaustion via EGR1-Gal3-LAG3 axis in glioblastoma
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    sciencedirect.com/science/article/pii/S0304383525006974
  72. Oct 2025
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    Proximity interactome mapping furthers a role for spinophilin in protein homeostasis
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    Identification of molecular markers and exploration of the oncogenic role of exomeres in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2211124725012318
  75. www.biorxiv.org www.biorxiv.org
    GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer
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    biorxiv.org/content/10.1101/2025.10.17.682994v1
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12500318/
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    Lipid-regulated phosphorylation hierarchy of the T cell receptor tyrosine motifs
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    sciencedirect.com/science/article/pii/S1097276525007464
  78. Sep 2025
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CA-125 as a Biomarker in Renal Medullary Carcinoma: Integrated Molecular Profiling, Functional Characterization, and Prospective Clinical Validation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11913570/
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    Structural insights into DdCBE in action enable high-precision mitochondrial DNA editing
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  81. www.biorxiv.org www.biorxiv.org
    The tumor suppressor CYLD acts as a deubiquitinase for mTOR to constrain its activity
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    biorxiv.org/content/10.1101/2025.09.01.673523v1
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    UBE2T promotes epithelial-mesenchymal transition and motility in oral cancer cells via induction of IL-6 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12365892/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PKN2 is a dependency of the mesenchymal-like cancer cell state
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875962/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1 Mutant Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12221223/pdf/can-24-3904.pdf
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875992/
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GCAD: a Computational Framework for Mammalian Genetic Program Computer-Aided Design
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    pmc.ncbi.nlm.nih.gov/articles/PMC12393561/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Conversion of natural cytokine receptors into orthogonal synthetic biosensors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12380174/
  88. www.nature.com www.nature.com
    Evaluating CAR-T cells from neurofibromatosis type 1 (NF1) patients for targeting AXL in malignant peripheral nerve sheath tumors associated with NF1
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    nature.com/articles/s41416-025-03151-w
  89. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225017389-main-html.html
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  90. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Distinct interaction modes orchestrate the polymerization of ASC PYD and CARD domains into filamentous structures
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70242
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    K29-Linked Ubiquitination of Transcription Regulators Controls Cell Proliferation in the Unfolded Protein Response
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202509817
  92. Aug 2025
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    Fibroblast bioelectric signaling drives hair growth
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    sciencedirect.com/science/article/pii/S0092867425008578
  94. www.biorxiv.org www.biorxiv.org
    Exploration of oncogenic cooperation between germline variation and somatic mutation in prostate cancer progression
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    biorxiv.org/content/10.1101/2025.08.05.668679v1
  95. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ENHANCED CLEAVAGE OF GENOMIC CCR5 USING CASX2Max
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    pmc.ncbi.nlm.nih.gov/articles/PMC12265720/
  96. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated real-time imaging of executioner caspase dynamics, apoptosis-induced proliferation, and immunogenic cell death using a stable fluorescent reporter platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328661/
  97. www.cell.com www.cell.com
    Systematic screening for functional exon-skipping isoforms using the CRISPR-RfxCas13d system
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  209. Mar 2024
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  222. Jan 2024
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