Hypothesis

32 Matching Annotations

Oct 2026
54.241.53.176 54.241.53.176

feb470321-sup-0001-supinfo-html.html

1
1. scibot 08 Oct 2026
  
  in Public
  
  CVCL_7916
  
  DOI: 10.1002/2211-5463.70321
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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54.241.53.176/0a435b08ab5ccb0130a494e1092e43ce7911f0be/feb470321-sup-0001-supinfo-html.html
Sep 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Bispecific Anti-Fluorescein × Anti-CD3 T-cell Engager in Combination with Fluoresceinated Adaptors Enables Lysis of AML Cells

1
1. scibot 04 Sep 2026
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/1535-7163.MCT-25-0985
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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pmc.ncbi.nlm.nih.gov/articles/PMC13535311/
Aug 2026
aacrjournals.org aacrjournals.org

Rapid Transcription Dynamics Confers Cytarabine Resistance in Acute Myeloid Leukemia

1
1. scibot 12 Aug 2026
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/2643-3230.BCD-25-0317
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

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aacrjournals.org/bloodcancerdiscov/article/7/4/624/786176/Rapid-Transcription-Dynamics-Confers-Cytarabine
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Development of CAR T cells Targeting a Surface RNA Binding Protein for the Treatment of Acute Leukemias

1
1. scibot 18 Jun 2026
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/2159-8290.CD-25-0920
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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pmc.ncbi.nlm.nih.gov/articles/PMC13271017/
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Activity of direct KRAS(G12C) inhibitors in preclinical models of pediatric cancer

1
1. scibot 06 May 2026
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/1535-7163.MCT-25-0022
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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pmc.ncbi.nlm.nih.gov/articles/PMC12776615/
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Enhancement of CD117-targeted bispecific T-cell engagement by CD33-targeted bispecific T-cell co-stimulation in acute myeloid leukemia

1
1. scibot 29 Apr 2026
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/2767-9764.CRC-25-0672
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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pmc.ncbi.nlm.nih.gov/articles/PMC13114487/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nutrient Availability Dictates Cancer Metabolism–Based Therapeutic Responses to Nononcology Drugs

1
1. scibot 09 Apr 2026
  
  in Public
  
  RRID: CVCL_7916
  
  DOI: 10.1158/0008-5472.CAN-25-1123
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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pmc.ncbi.nlm.nih.gov/articles/PMC13055633/
Jan 2026
www.sciencedirect.com www.sciencedirect.com

Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia

1
1. scibot 09 Jan 2026
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1016/j.chembiol.2025.12.002
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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sciencedirect.com/science/article/pii/S2451945625003952
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Retinoic acid and ascorbate synergize to suppress myeloid leukemia via TET2 activation

1
1. scibot 02 Oct 2025
  
  in Public
  
  DSMZACC 777
  
  DOI: 10.1016/j.celrep.2025.116379
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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sciencedirect.com/science/article/pii/S2211124725011507
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An isoform-specific RUNX1C–BTG2 axis governs AML quiescence and chemoresistance.

1
1. scibot 07 Sep 2025
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/2643-3230.BCD-24-0327
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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pmc.ncbi.nlm.nih.gov/articles/PMC12405853/
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Genome-wide CRISPR screens identify critical targets to enhance CAR-NK cell antitumor potency

1
1. scibot 26 Aug 2025
  
  in Public
  
  DSZMCat# ACC 777
  
  DOI: 10.1016/j.ccell.2025.07.021
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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sciencedirect.com/science/article/pii/S1535610825003277
Apr 2025
aacrjournals.org aacrjournals.org

Preclinical Development of Tuspetinib for the Treatment of Acute Myeloid Leukemia

1
1. scibot 17 Apr 2025
  
  in Public
  
  ACC 777
  
  DOI: 10.1158/2767-9764.CRC-24-0258
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

aacrjournals.org/cancerrescommun/article/5/1/74/751014/Preclinical-Development-of-Tuspetinib-for-the
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway

1
1. scibot 13 Mar 2025
  
  in Public
  
  CVCL_7916
  
  DOI: 10.21203/rs.3.rs-6017610/v1
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11875301/
Dec 2024
www.sciencedirect.com www.sciencedirect.com

ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis

1
1. scibot 02 Dec 2024
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1016/j.celrep.2024.114988
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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URL

sciencedirect.com/science/article/pii/S2211124724013391
Sep 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 27 Sep 2024
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1111/febs.17263
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_7916
  
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  DOI:10.1111/febs.17263 RRID:CVCL_7916
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RRID:CVCL_7916

DOI:10.1111/febs.17263

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scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1111/febs.17263
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Use of Payload Binding Selectivity Enhancers to Improve Therapeutic Index of Maytansinoid-Antibody-Drug Conjugates

1
1. scibot 02 May 2024
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/1535-7163.MCT-22-0804
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC10811745/
Apr 2024
52.53.155.43 52.53.155.43

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1

1
1. scibot 11 Apr 2024
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1016/j.isci.2024.109576
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

52.53.155.43/43deb73e3f715bad3d2167b3c6b37658d9cd796b/1-s2.0-S2589004224007983-main-html.html
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pim kinase inhibitors increase gilteritinib cytotoxicity in FLT3-ITD acute myeloid leukemia through GSK-3β activation and c-Myc and Mcl-1 proteasomal degradation

1
1. scibot 21 Feb 2024
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/2767-9764.CRC-23-0379
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10870818/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML

1
1. scibot 22 Nov 2023
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1016/j.xcrm.2023.101290
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

sciencedirect.com/science/article/pii/S2666379123004846
Sep 2023
www.sciencedirect.com www.sciencedirect.com

PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy

1
1. scibot 08 Sep 2023
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1016/j.xcrm.2023.101191
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

sciencedirect.com/science/article/pii/S2666379123003580
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting MET and FGFR in Relapsed or Refractory Acute Myeloid Leukemia: Preclinical and Clinical Findings, and Signal Transduction Correlates

1
1. scibot 07 Sep 2023
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/1078-0432.CCR-22-2540
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9992000/
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells

1
1. scibot 10 Mar 2023
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1016/j.ccell.2023.02.010
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
May 2022
www.sciencedirect.com www.sciencedirect.com

Antigen presentation safeguards the integrity of the hematopoietic stem cell pool

1
1. scibot 06 May 2022
  
  in Public
  
  DSMZACC 777
  
  DOI: 10.1016/j.stem.2022.04.007
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

sciencedirect.com/science/article/pii/S1934590922001606
Apr 2022
aacrjournals.org aacrjournals.org

Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia

1
1. scibot 05 Apr 2022
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/2159-8290.CD-21-0692
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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URL

aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A method for overcoming plasma protein inhibition of tyrosine kinase inhibitors

1
1. scibot 30 Sep 2021
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1158/2643-3230.bcd-20-0119
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8478262/
Jun 2021
www.sciencedirect.com www.sciencedirect.com

ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia

1
1. scibot 03 Jun 2021
  
  in Public
  
  ACC777
  
  DOI: 10.1016/j.molcel.2021.05.008
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_7916
  
  What is this?
  
  RRID:CVCL_7916 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_7916

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scibot

URL

sciencedirect.com/science/article/pii/S1097276521003658
May 2021
www.sciencedirect.com www.sciencedirect.com

Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML

1
1. scibot 11 May 2021
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.1016/j.molcel.2021.04.014
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_7916
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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URL

sciencedirect.com/science/article/pii/S1097276521003191
www.sciencedirect.com www.sciencedirect.com

Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis

1
1. scibot 01 May 2021
  
  in Public
  
  ACC-777
  
  DOI: 10.1016/j.cmet.2021.03.003
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_7916
  
  What is this?
  
  RRID:CVCL_7916 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_7916

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scibot

URL

sciencedirect.com/science/article/pii/S1550413121001108
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia

1
1. scibot 22 Apr 2021
  
  in Public
  
  ACC 777
  
  DOI: 10.1016/j.ccell.2020.10.010
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_7916
  
  What is this?
  
  RRID:CVCL_7916 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_7916

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scibot

URL

sciencedirect.com/science/article/pii/S1535610820305419
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_7916
  
  DOI: 10.7554/eLife.40033
  
  Resource: (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_7916
  
  What is this?
  
  RRID:CVCL_7916 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_7916

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6363389/
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_7916
  
  Resource used:
  
  (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  SciCrunch record: RRID:CVCL_7916
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_7916
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RRID:CVCL_7916

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6427047/
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  ACC 777
  
  Curator: @Jmenke
  
  Resource used:
  
  (DSMZ Cat# ACC-777, RRID:CVCL_7916)
  
  SciCrunch record: RRID:CVCL_7916
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_7916 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_7916

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scibot

URL

sciencedirect.com/science/article/pii/S1535610817303641