Hypothesis

16 Matching Annotations

Last 7 days
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Discovery of α-Adrenoceptor Antagonists as a Potential New Treatment Option for Uveal Melanoma

1
1. scibot 01 Nov 2025
  
  in Public
  
  CVCL_8607
  
  DOI: 10.3390/biom15101436
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12563263/
Oct 2025
www.biorxiv.org www.biorxiv.org

A computational SOX10 network-based selection strategy to identify new drug targets in uveal melanoma

1
1. scibot 21 Oct 2025
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.1101/2025.10.14.679939
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

biorxiv.org/content/10.1101/2025.10.14.679939v1
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CRISPR-Cas13d-Mediated Targeting of a Context-Specific Essential Gene Enables Selective Elimination of Uveal Melanoma

1
1. scibot 06 Sep 2025
  
  in Public
  
  CVCL_8607
  
  DOI: 10.1101/2025.08.21.671629
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12393512/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Allele-specific depletion of GNAQQ209L via siRNA or a rAAV2-shRNA vector induces selective toxicity in GNAQQ209L uveal melanoma cells

1
1. scibot 14 Aug 2025
  
  in Public
  
  CVCL_8607
  
  DOI: 10.1016/j.omton.2025.201020
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12341522/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Non-invasive multi-cancer detection using DNA hypomethylation of LINE-1 retrotransposons

1
1. scibot 04 Apr 2025
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.1158/1078-0432.CCR-24-2669
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11959274/
Feb 2025
52.53.155.43 52.53.155.43

ccr-24-2669-html.html

1
1. scibot 13 Feb 2025
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.1158/1078-0432.ccr-24-2669
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

52.53.155.43/45c0c89230ea298066b0c6f4038dbadba7e2782f/ccr-24-2669-html.html
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation

1
1. scibot 20 Jul 2024
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.1038/s41540-024-00400-1
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11252164/
May 2024
www.biorxiv.org www.biorxiv.org

Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma

1
1. scibot 03 May 2024
  
  in Public
  
  RRID: CVCL_8607)
  
  DOI: 10.1101/2024.01.12.575058
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

biorxiv.org/content/10.1101/2024.01.12.575058v1
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression

1
1. scibot 06 Jul 2023
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.1158/1535-7163.MCT-22-0147
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9812929/
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma

1
1. scibot 19 Jan 2023
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.1016/j.xcrm.2022.100915
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379122004943
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting IRS-1/2 in Uveal Melanoma Inhibits In Vitro Cell Growth, Survival and Migration, and In Vivo Tumor Growth

1
1. scibot 31 Dec 2022
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.3390/cancers14246247
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9777326/
Dec 2021
www.sciencedirect.com www.sciencedirect.com

Oncogenic Gq/11 signaling acutely drives and chronically sustains metabolic reprogramming in uveal melanoma

1
1. scibot 21 Dec 2021
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.1016/j.jbc.2021.101495
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0021925821013053
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Uveal melanoma cells use ameboid and mesenchymal mechanisms of cell motility crossing the endothelium

1
1. scibot 19 May 2021
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.1091/mbc.E20-04-0241
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8098856/
Feb 2021
www.sciencedirect.com www.sciencedirect.com

Targeting primary and metastatic uveal melanoma with a G protein inhibitor

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.1016/j.jbc.2021.100403
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0021925821001757
Jan 2020
iovs.arvojournals.org iovs.arvojournals.org

Elevated Endogenous SDHA Drives Pathological Metabolism in Highly Metastatic Uveal Melanoma

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_8607
  
  DOI: 10.1167/iovs.19-28082
  
  Resource: (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_8607
  
  What is this?
  
  RRID:CVCL_8607 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:CVCL_8607

RRIDCUR:Validated

Annotators

scibot

URL

iovs.arvojournals.org/article.aspx
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_8607
  
  Resource used:
  
  (ICLC Cat# HTL12001, RRID:CVCL_8607)
  
  SciCrunch record: RRID:CVCL_8607
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_8607
Visit annotations in context

Tags

RRID:CVCL_8607

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610818300023