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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proteomic and functional comparison between human induced and embryonic stem cells
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    1. scibot 22 Dec 2024
      RRID:CVCL_9771

      DOI: 10.7554/eLife.92025

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    pmc.ncbi.nlm.nih.gov/articles/PMC11563575/
  3. 52.53.155.43 52.53.155.43
    1-s2.0-S2352345X24001991-main-html.html
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    1. scibot 18 Dec 2024
      RRID:CVCL_9771

      DOI: 10.1016/j.jcmgh.2024.101444

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    52.53.155.43/097e48fb05b2c34468ef14c01170b95cad33661e/1-s2.0-S2352345X24001991-main-html.html
  4. Dec 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Generation of self-organized neuromusculoskeletal tri-tissue organoids from human pluripotent stem cells
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    1. scibot 10 Dec 2024
      RRID:CVCL_9771

      DOI: 10.1016/j.stem.2024.11.005

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    sciencedirect.com/science/article/pii/S1934590924004041
  6. www.sciencedirect.com www.sciencedirect.com
    KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons
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    1. scibot 10 Dec 2024
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      DOI: 10.1016/j.nbd.2024.106759

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    sciencedirect.com/science/article/pii/S0969996124003619
  7. Nov 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Generation of self-renewing neuromesodermal progenitors with neuronal and skeletal muscle bipotential from human embryonic stem cells
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    1. scibot 17 Nov 2024
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      DOI: 10.1016/j.crmeth.2024.100897

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    sciencedirect.com/science/article/pii/S266723752400287X
  9. Oct 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Protocol for the efficient and inducible generation of CRISPR-Cas9-edited human cortical neurons from the iCas9-iNgn2 hPSCs
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    1. scibot 02 Oct 2024
      RRID:CVCL_9771

      DOI: 10.1016/j.xpro.2024.103352

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    sciencedirect.com/science/article/pii/S2666166724005173
  11. Sep 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons
    1
    1. scibot 28 Sep 2024
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      DOI: 10.1101/2024.09.06.611684

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    ncbi.nlm.nih.gov/pmc/articles/PMC11418931/
  13. academic.oup.com academic.oup.com
    Transcriptome comparisons of trophoblasts from regenerative cell models with peri-implantation human embryos
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    1. scibot 28 Sep 2024
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      DOI: 10.1093/biolre/ioae120

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    academic.oup.com/biolreprod/advance-article-abstract/doi/10.1093/biolre/ioae120/7728794
  14. www.sciencedirect.com www.sciencedirect.com
    RAPIDASH: Tag-free enrichment of ribosome-associated proteins reveals composition dynamics in embryonic tissue, cancer cells, and macrophages
    1
    1. scibot 13 Sep 2024
      Cat# WA01

      DOI: 10.1016/j.molcel.2024.08.023

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    sciencedirect.com/science/article/pii/S1097276524007007
  15. www.sciencedirect.com www.sciencedirect.com
    Protocol for CRISPR-Cas12a genome editing of protein tyrosine phosphatases in human pluripotent stem cells and functional β-like cell generation
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.xpro.2024.103297

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    sciencedirect.com/science/article/pii/S2666166724004623
  16. www.sciencedirect.com www.sciencedirect.com
    Protocol for generating human cortical organoids enriched in outer radial glia by guided differentiation
    1
    1. scibot 04 Sep 2024
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      DOI: 10.1016/j.xpro.2024.103280

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    sciencedirect.com/science/article/pii/S2666166724004453
  17. Aug 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes
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    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.immuni.2024.07.019

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    sciencedirect.com/science/article/pii/S1074761324003686
  19. www.nature.com www.nature.com
    Nanometer-resolution tracking of single cargo reveals dynein motor mechanisms
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    1. scibot 18 Aug 2024
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      DOI: 10.1038/s41589-024-01694-2

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    nature.com/articles/s41589-024-01694-2
  20. www.sciencedirect.com www.sciencedirect.com
    A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development
    1
    1. scibot 15 Aug 2024
      Cat# WA01

      DOI: 10.1016/j.stem.2024.07.006

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    sciencedirect.com/science/article/pii/S193459092400256X
  21. Jul 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGF-β modulates cell fate in human ES cell-derived foregut endoderm by inhibiting Wnt and BMP signaling
    1
    1. scibot 20 Jul 2024
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      DOI: 10.1016/j.stemcr.2024.05.010

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    ncbi.nlm.nih.gov/pmc/articles/PMC11252478/
  23. www.sciencedirect.com www.sciencedirect.com
    A human pluripotent stem cell-based somitogenesis model using microfluidics
    1
    1. scibot 17 Jul 2024
      WiCellWA01

      DOI: 10.1016/j.stem.2024.06.004

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    sciencedirect.com/science/article/pii/S1934590924002121
  24. May 2024
  25. www.biorxiv.org www.biorxiv.org
    Human Pluripotent Stem Cell Derived Organoids Reveal a Role for WNT Signaling in Dorsal-Ventral Patterning of the Hindgut
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    1. scibot 16 May 2024
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      DOI: 10.1101/2024.03.04.583343

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    biorxiv.org/content/10.1101/2024.03.04.583343v1
  26. www.sciencedirect.com www.sciencedirect.com
    Activating innate immune responses repolarizes hPSC-derived CAR macrophages to improve anti-tumor activity
    1
    1. scibot 09 May 2024
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    sciencedirect.com/science/article/pii/S1934590924001395
  27. 52.53.155.43 52.53.155.43
    Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids
    2
    1. scibot 09 May 2024
      RRID:CVCL_9771

      DOI: 10.1016/j.celrep.2024.114173

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    2. scibot 03 May 2024
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      DOI: 10.1016/j.celrep.2024.114173

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    52.53.155.43/7165d3b920717872e9ecee45ef5f3cb3a7917c57/mmc6-html.html
  28. 52.53.155.43 52.53.155.43
    hESC- and hiPSC-derived Schwann cells are Molecularly Comparable and Functionally Equivalent
    1
    1. scibot 03 May 2024
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      DOI: 10.1016/j.isci.2024.109855

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    52.53.155.43/56e8c9d208a0f814f47b8f2a9e78948656d34d4d/PIIS2589004224010770-html.html
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution
    1
    1. scibot 01 May 2024
      RRID:CVCL_9771

      DOI: 10.1158/0008-5472.CAN-22-2872

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    ncbi.nlm.nih.gov/pmc/articles/PMC11022245/
  30. Apr 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Generation of human cerebral organoids with a structured outer subventricular zone
    1
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114031

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    sciencedirect.com/science/article/pii/S2211124724003590
  32. Dec 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex difference in liver diseases: How preclinical models help to dissect the sex-related mechanisms sustaining NAFLD and hepatocellular carcinoma
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1016/j.isci.2023.108363

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    ncbi.nlm.nih.gov/pmc/articles/PMC10682354/
  34. Nov 2023
  35. www.nature.com www.nature.com
    Scalable single-cell profiling of chromatin modifications with sciCUT&Tag
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    1. scibot 17 Nov 2023
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      DOI: 10.1038/s41596-023-00905-9

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    nature.com/articles/s41596-023-00905-9
  36. www.sciencedirect.com www.sciencedirect.com
    Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.stem.2023.10.002

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    sciencedirect.com/science/article/pii/S1934590923003648
  37. Oct 2023
  38. www.sciencedirect.com www.sciencedirect.com
    The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2
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    1. scibot 13 Oct 2023
      RRID:CVCL_9771

      DOI: 10.1016/j.celrep.2023.113222

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    sciencedirect.com/science/article/pii/S2211124723012342
  39. Aug 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity
    1
    1. scibot 31 Aug 2023
      RRID:CVCL_9771

      DOI: 10.1016/j.isci.2023.107525

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    ncbi.nlm.nih.gov/pmc/articles/PMC10460991/
  41. link.springer.com link.springer.com
    Ethanol Causes Cell Death and Neuronal Differentiation Defect During Initial Neurogenesis of the Neural Retina by Disrupting Calcium Signaling in Human Retinal Organoids
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    1. scibot 23 Aug 2023
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      DOI: 10.1007/s12015-023-10604-3

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    link.springer.com/article/10.1007/s12015-023-10604-3
  42. www.sciencedirect.com www.sciencedirect.com
    Human microglia maturation is underpinned by specific gene regulatory networks
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    1. scibot 16 Aug 2023
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      DOI: 10.1016/j.immuni.2023.07.016

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    sciencedirect.com/science/article/pii/S1074761323003291
  43. Jul 2023
  44. www.science.org www.science.org
    Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment
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    1. scibot 25 Jul 2023
      RRID:CVCL_9771

      DOI: 10.1126/scitranslmed.adg1659

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    science.org/doi/10.1126/scitranslmed.adg1659
  45. www.sciencedirect.com www.sciencedirect.com
    Orphan quality control shapes network dynamics and gene expression
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    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.cell.2023.06.015

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    sciencedirect.com/science/article/pii/S0092867423006918
  46. Jun 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells
    2
    1. scibot 16 Jun 2023
      RRID: CVCL_9771

      DOI: 10.1016/j.isci.2023.106995

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      DOI: 10.1016/j.isci.2023.106995

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    sciencedirect.com/science/article/pii/S2589004223010726
  48. www.sciencedirect.com www.sciencedirect.com
    SETD7 promotes lateral plate mesoderm formation by modulating the Wnt/β-catenin signaling pathway
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    1. scibot 02 Jun 2023
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      DOI: 10.1016/j.isci.2023.106917

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    sciencedirect.com/science/article/pii/S258900422300994X
  49. May 2023
  50. www.nature.com www.nature.com
    Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs
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    1. scibot 28 May 2023
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      DOI: 10.1038/s41536-023-00302-6

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    nature.com/articles/s41536-023-00302-6
  51. www.sciencedirect.com www.sciencedirect.com
    An in vivo neuroimmune organoid model to study human microglia phenotypes
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    1. scibot 12 May 2023
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      DOI: 10.1016/j.cell.2023.04.022

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    sciencedirect.com/science/article/pii/S009286742300418X
  52. Mar 2023
  53. www.sciencedirect.com www.sciencedirect.com
    hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung’s disease
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    1. scibot 03 Mar 2023
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      DOI: 10.1016/j.stem.2023.02.003

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    sciencedirect.com/science/article/pii/S1934590923000401
  54. Feb 2023
  55. www.mdpi.com www.mdpi.com
    Characterization of De Novo Promoter Variants in Autism Spectrum Disorder with Massively Parallel Reporter Assays
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    1. scibot 16 Feb 2023
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      DOI: 10.3390/ijms24043509

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    mdpi.com/1422-0067/24/4/3509
  56. Jan 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRPF1 bridges H3K4me3 and H3K23ac in human ESCs and is essential to pluripotency
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    1. scibot 28 Jan 2023
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      DOI: 10.1016/j.isci.2023.105939

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    ncbi.nlm.nih.gov/pmc/articles/PMC9874078/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Attenuating iPSC reprogramming stress with dominant-negative BET peptides
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    1. scibot 25 Jan 2023
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      DOI: 10.1016/j.isci.2022.105889

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    ncbi.nlm.nih.gov/pmc/articles/PMC9860338/
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Dysregulated cholesterol metabolism, aberrant excitability and altered cell cycle of astrocytes in fragile X syndrome
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    1. scibot 12 Jan 2023
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      DOI: 10.1002/glia.24331

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  60. Oct 2022
  61. www.nature.com www.nature.com
    Efficient and safe single-cell cloning of human pluripotent stem cells using the CEPT cocktail
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  62. Aug 2022
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    Protocol to derive human trophoblast stem cells directly from primed pluripotent stem cells
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  64. www.nature.com www.nature.com
    Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems
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  65. Jul 2022
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    Protocol for germ lineage differentiation of primed human pluripotent stem cells using chemically defined, nutrient-balanced media
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    HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs
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  68. Apr 2022
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    Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells
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  70. Feb 2022
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    HiCAR is a robust and sensitive method to analyze open-chromatin-associated genome organization
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    Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture
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  73. Jan 2022
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    Single-cell ATAC-seq of fetal human retina and stem-cell-derived retinal organoids shows changing chromatin landscapes during cell fate acquisition
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  75. Nov 2021
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    Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus
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    Modulating mesendoderm competence during human germ layer differentiation
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  78. Aug 2021
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    Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding
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  81. academic.oup.com academic.oup.com
    StereoGene: rapid estimation of genome-wide correlation of continuous or interval feature data
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  84. Jul 2021
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    Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
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  86. www.biorxiv.org www.biorxiv.org
    StereoGene: Rapid Estimation of Genomewide Correlation of Continuous or Interval Feature Data
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  88. Jun 2021
  89. elifesciences.org elifesciences.org
    SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome patients
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  90. May 2021
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    Decoding Human Megakaryocyte Development
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    The cis-regulatory effects of modern human-specific variants
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  93. Apr 2021
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    High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells
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  95. Mar 2021
  96. www.cell.com www.cell.com
    Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures
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  97. Feb 2021
  98. elifesciences.org elifesciences.org
    Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development
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  99. www.nature.com www.nature.com
    Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells
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  100. elifesciences.org elifesciences.org
    Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation
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  101. www.jneurosci.org www.jneurosci.org
    Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  103. Jan 2021
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    Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells
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  105. Dec 2020
  106. www.nature.com www.nature.com
    A microfluidics-based stem cell model of early post-implantation human development
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    High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures
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  108. www.sciencedirect.com www.sciencedirect.com
    hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allografts
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  109. Sep 2020
  110. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    An Optimized Protocol for ChIP-Seq from Human Embryonic Stem Cell Cultures
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    mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex
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  112. www.cell.com www.cell.com
    Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
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  113. www.sciencedirect.com www.sciencedirect.com
    GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells
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    A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation
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    Generating Patient-Derived Gliomas within Cerebral Organoids
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  116. Jan 2020
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    Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
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    Pioneer Factor-Nucleosome Binding Events during Differentiation Are Motif Encoded
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    Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA
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    Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
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    1. scibot 13 Jan 2020
      RRID:CVCL_9771

      DOI: 10.1016/j.celrep.2019.02.041

      Resource: (RRID:CVCL_9771)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_9771

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      RRID:CVCL_9771 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719302128
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling Patient-Derived Glioblastoma with Cerebral Organoids
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_9771

      DOI: 10.1016/j.celrep.2019.02.063

      Resource: (RRID:CVCL_9771)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_9771

      What is this?

      RRID:CVCL_9771 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6625753/
  122. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 12 Jan 2020
      RRID:CVCL_9771

      DOI: 10.1016/j.celrep.2019.02.016

      Resource: (RRID:CVCL_9771)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_9771

      What is this?

      RRID:CVCL_9771 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719301780
  123. Nov 2017
  124. www.sciencedirect.com www.sciencedirect.com
    A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages
    1
    1. scibot 08 Nov 2017
      NIHhESC-10-0043

      Curator: @Jmenke

      Resource used:

      RRID:CVCL_9771

      SciCrunch record: RRID:CVCL_9771

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_9771 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1934590917303338
  125. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation
    1
    1. scibot 08 Nov 2017
      CVCL_9771

      Curator: @gabimpine

      Resource used:

      RRID:CVCL_9771

      SciCrunch record: RRID:CVCL_9771

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:CVCL_9771 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627317300983
  126. www.sciencedirect.com www.sciencedirect.com
    ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion
    1
    1. scibot 08 Nov 2017
      Cat# WA01

      Curator: @Zeljana_Babic

      Resource used:

      RRID:CVCL_9771

      SciCrunch record: RRID:CVCL_9771

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:CVCL_9771 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867416317603