33 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13717119/
  3. Oct 2026
  4. www.sciencedirect.com www.sciencedirect.com
    A feedback mechanism of m6A via PARP1-mediated ADP ribosylation of METTL3/METTL14
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    sciencedirect.com/science/article/pii/S1097276526006714
  5. Apr 2026
  6. 54.241.53.176 54.241.53.176
    2026.04.20.719456.full-html.html
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    54.241.53.176/6790efd246ed84de929dd028ff8d6465bfa7b2e6/2026.04.20.719456.full-html.html
  7. www.science.org www.science.org
    Multiomics profiling and experiments in preclinical models revealed RAD51-IN-1 as a synergistic potentiator of anlotinib sensitivity
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    science.org/doi/10.1126/sciadv.aeb0855
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DHX9 inhibition enhances paclitaxel sensitivity by inducing mitotic failure in ovarian and endometrial cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC13098759/
  9. 54.241.53.176 54.241.53.176
    mct-25-0268-html.html
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    54.241.53.176/a412b4ecb928f944e0b118b139f1e81bba8c2102/mct-25-0268-html.html
  10. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226010862-main-html.html
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    54.241.53.176/be028d43344bab6907bc9e771fd88e2dec1a0cd7/1-s2.0-S2589004226010862-main-html.html
  11. Jan 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations
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    pmc.ncbi.nlm.nih.gov/articles/PMC13019158/
  13. Nov 2025
  14. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70224
  15. Oct 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PARP inhibitor and PRMT5 inhibitor synergy is independent of BRCA1/2 and MTAP status in breast cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12540990/
  17. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70126
  18. Aug 2025
  19. www.sciencedirect.com www.sciencedirect.com
    Coordinated protein modules define DNA damage responses to carboplatin at single-cell resolution in human ovarian carcinoma models
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    sciencedirect.com/science/article/pii/S2666379125003684
  20. Dec 2024
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC11621922/
  22. Nov 2024
  23. www.sciencedirect.com www.sciencedirect.com
    Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer
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    sciencedirect.com/science/article/pii/S2589004224025082
  24. Sep 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic effects of PARP inhibition and cholesterol biosynthesis pathway modulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11403291/
  26. Jan 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10105475/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In silico enhancer mining reveals SNS-032 and EHMT2 inhibitors as therapeutic candidates in high-grade serous ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10307814/
  29. www.sciencedirect.com www.sciencedirect.com
    Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
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    sciencedirect.com/science/article/pii/S2666379123006055
  30. Dec 2023
  31. www.sciencedirect.com www.sciencedirect.com
    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    sciencedirect.com/science/article/pii/S2666379123005438
  32. Jul 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATF6-mediated signaling contributes to PARP Inhibitor Resistance in Ovarian Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9812934/
  34. Apr 2023
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Unveiling the epigenomic mechanisms of acquired platinum-resistance in high-grade serous ovarian cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34496
  36. Feb 2023
  37. www.embopress.org www.embopress.org
    Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma
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    embopress.org/doi/10.15252/emmm.202216863
  38. Dec 2022
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
  40. Apr 2022
  41. aacrjournals.org aacrjournals.org
    Loss of Claudin-4 Reduces DNA Damage Repair and Increases Sensitivity to PARP Inhibitors
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    aacrjournals.org/mct/article/21/4/647/689566/Loss-of-Claudin-4-Reduces-DNA-Damage-Repair-and
  42. Feb 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Systematic illumination of druggable genes in cancer genomes
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    sciencedirect.com/science/article/pii/S2211124722001218
  44. Oct 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells
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    sciencedirect.com/science/article/pii/S1097276521007474
  46. Sep 2021
  47. www.sciencedirect.com www.sciencedirect.com
    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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    sciencedirect.com/science/article/pii/S1097276521006833
  48. Aug 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124718318175
  50. Jul 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
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    sciencedirect.com/science/article/pii/S2211124721008251
  52. Mar 2021
  53. www.sciencedirect.com www.sciencedirect.com
    DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1
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    sciencedirect.com/science/article/pii/S2211124721001546
  54. Jan 2020
  55. www.mdpi.com www.mdpi.com
    The Metabolic Inhibitor CPI-613 Negates Treatment Enrichment of Ovarian Cancer Stem Cells
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    mdpi.com/2072-6694/11/11/1678/htm
  56. mcr.aacrjournals.org mcr.aacrjournals.org
    PARP Inhibition Induces Enrichment of DNA Repair–Proficient CD133 and CD117 Positive Ovarian Cancer Stem Cells
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    mcr.aacrjournals.org/content/17/2/431
  57. Nov 2018
  58. www.sciencedirect.com www.sciencedirect.com
    BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
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    sciencedirect.com/science/article/pii/S2211124718314050