112 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    tRF3a-MetCAT Promotes EGFR-Targeted Therapeutic Resistance through the TRIM21–STAT1–C5a Axis in Lung Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12501432/
  3. Oct 2025
  4. www.biorxiv.org www.biorxiv.org
    Associative memory in human cancer cells
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    biorxiv.org/content/10.1101/2025.09.29.679179v1
  5. Sep 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In situ RAS:RAF binding correlates with response to KRASG12C inhibitors in KRASG12C-mutant non–small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11924342/
  7. www.nature.com www.nature.com
    A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2
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    nature.com/articles/s41587-025-02793-8
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Eradicating Drug Tolerant Persister Cells in EGFR-Mutated Non-Small Cell Lung Cancer by Targeting TROP2 with CAR-T cellular therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12374242/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PKN2 is a dependency of the mesenchymal-like cancer cell state
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875962/
  10. Aug 2025
  11. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70238
  12. www.sciencedirect.com www.sciencedirect.com
    Synthesis, Characterization and Antitumor Assessments of Sulfonamide-1,2,4-Triazole Compounds with EGRF inhibitory Potential: DFT Calculation, Molecular Docking, Molecular Dynamics, and MM/PBSA Approaches
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    sciencedirect.com/science/article/pii/S0022286025023968
  13. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    HACD3 promotes malignant progression of NSCLC by suppressing the MKK7/MAPK10 signaling axis
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    bmccancer.biomedcentral.com/articles/10.1186/s12885-025-14621-y
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    Dapk2 dysfunction leads to Mic60 lactylation and mitochondrial metabolic reprogramming, promoting lung cancer EGFR-TKI resistance and metastasis
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    sciencedirect.com/science/article/pii/S153458072500471X
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    sciencedirect.com/science/article/pii/S1535610825003101
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FBXW5 Promotes Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Through the KLF13/TROAP Signaling Pathway
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.70018
  17. Jul 2025
  18. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70096
  19. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Prediction of Lung Cancer Metastasis Risk Based on Single-Cell Metabolic Profiling of Circulating Tumor Cells
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202508878
  20. Jun 2025
  21. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Splicing Shift of RAC1 Accelerates Tumorigenesis and Defines a Potent Therapeutic Target in Lung Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202503322
  22. 52.53.155.43 52.53.155.43
    1-s2.0-S155608642500766X-main-html.html
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    52.53.155.43/948e09910b1ed27c4203114717163170d10423c7/1-s2.0-S155608642500766X-main-html.html
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cathepsin C correlates with M2 macrophage infiltration and regulates the tumor growth and metastasis in non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12139067/
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    Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation
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    sciencedirect.com/science/article/pii/S2451945625001667
  25. May 2025
  26. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    FAT1 Enhances the Sensitivity of Non-Small Cell Lung Cancer to VCP Inhibitors by Regulating the Activation of the Endoplasmic Reticulum Stress Pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500097RR
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    hnRNPA2B1 potentiates the immune escape of non-small cell lung cancer by accelerating tumor microenvironment acidification
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    sciencedirect.com/science/article/pii/S0891584925006781
  28. Apr 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225006480-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12063144/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EFTUD2 is a promising diagnostic and prognostic indicator involved in the tumor immune microenvironment and glycolysis of lung adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11996642/
  31. www.sciencedirect.com www.sciencedirect.com
    Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
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    sciencedirect.com/science/article/pii/S0092867425002909
  32. Mar 2025
  33. www.sciencedirect.com www.sciencedirect.com
    Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S1097276525001947
  34. Feb 2025
  35. aacrjournals.org aacrjournals.org
    TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma
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    aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
  36. Jan 2025
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NRP1 overexpression potentially enhances osimertinib resistance in NSCLC via activation of the PI3K/AKT signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11711526/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intratumor heterogeneity of EGFR expression mediates targeted therapy resistance and formation of drug tolerant microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695629/
  39. www.sciencedirect.com www.sciencedirect.com
    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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    sciencedirect.com/science/article/pii/S1074761324005685
  40. Dec 2024
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pericytes Modulate Third‐Generation Tyrosine Kinase Inhibitor Sensitivity in EGFR‐Mutated Lung Cancer Cells Through IL32‐β5‐Integrin Paracrine Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11633494/
  42. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
  43. Sep 2024
  44. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
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    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    sciencedirect.com/science/article/pii/S2666379124004245
  46. Aug 2024
  47. www.pnas.org www.pnas.org
    Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer
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    pnas.org/doi/10.1073/pnas.2319429121
  48. aacrjournals.org aacrjournals.org
    MTX-13, a novel PTK7-directed antibody-drug conjugate with widened therapeutic index shows sustained tumor regressions for a broader spectrum of PTK7-positive tumors
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    aacrjournals.org/mct/article/22/10/1128/729312/MTX-13-a-Novel-PTK7-Directed-Antibody-Drug
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockade of STAT3/IL-4 overcomes EGFR T790M-cis-L792F-induced resistance to osimertinib via suppressing M2 macrophages polarization
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    ncbi.nlm.nih.gov/pmc/articles/PMC9358434/
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    Myeloid cell differentiation-related gene signature for predicting clinical outcome, immune microenvironment, and treatment response in lung adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11286868/
  51. Jul 2024
  52. www.sciencedirect.com www.sciencedirect.com
    Incense-burning smoke ingredient Auramine enhances lincRNA-p21 expression for chemosensitization in p53-mutated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0304389424016844
  53. Jun 2024
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Morphological basis of the lung adenocarcinoma subtypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11066476/
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    Accelerated drug-resistant variant discovery with an enhanced, scalable mutagenic base editor platform
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    sciencedirect.com/science/article/pii/S2211124724006417
  56. May 2024
  57. aacrjournals.org aacrjournals.org
    Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC
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    aacrjournals.org/clincancerres/article/30/8/1582/742134/Discovery-of-a-Novel-Potent-EGFR-Inhibitor-Against
  58. aacrjournals.org aacrjournals.org
    TNFRSF19 within the 13q12.12 risk locus functions as a lung cancer suppressor by binding Wnt3a to inhibit Wnt/β-catenin signaling.
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    aacrjournals.org/mcr/article/22/3/227/734703/TNFRSF19-within-the-13q12-12-Risk-Locus-Functions
  59. Apr 2024
  60. aacrjournals.org aacrjournals.org
    EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth
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    aacrjournals.org/cancerdiscovery/article/14/3/524/734906/EGFR-Driven-Lung-Adenocarcinomas-Co-opt-Alveolar
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Omics Analysis Identifies CCR6 as a Therapeutic Target to Overcome Cancer Resistance to EGFR Inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10972824/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent STAT3-K631 acetylation and its Y705-phosphorylation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10972722/
  63. Mar 2024
  64. www.sciencedirect.com www.sciencedirect.com
    A single-cell characterised signature integrating heterogeneity and microenvironment of lung adenocarcinoma for prognostic stratification
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    sciencedirect.com/science/article/pii/S2352396424001270
  65. www.sciencedirect.com www.sciencedirect.com
    Silibinin is a suppressor of the metastasis-promoting transcription factor ID3
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    sciencedirect.com/science/article/pii/S0944711324001570
  66. Feb 2024
  67. 52.53.155.43 52.53.155.43
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    52.53.155.43/f092aa63506937030df3074397696edbfe46ccc6/d4-html.html
  68. www.sciencedirect.com www.sciencedirect.com
    Sialyltransferase ST3GAL4 confers osimertinib resistance and offers strategies to overcome resistance in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0304383524001551
  69. www.biorxiv.org www.biorxiv.org
    Saturation resistance profiling of EGFR variants against tyrosine kinase inhibitors using prime editing
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    biorxiv.org/content/10.1101/2023.12.03.569825v1
  70. Jan 2024
  71. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13564
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ modeling of acquired resistance to RTK/RAS pathway targeted therapies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788224/
  73. Dec 2023
  74. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Integrative analyses of N6-methyladenosine-associated single-nucleotide polymorphisms (m6A-SNPs) identify tumor suppressor gene AK9 in lung cancer
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    onlinelibrary.wiley.com/doi/10.1002/mc.23669
  75. Nov 2023
  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34783
  77. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
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    52.53.155.43/fa9809949a94f3d698a02ed4d13d532c010d3e91/British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
  78. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13505
  79. Oct 2023
  80. www.cell.com www.cell.com
    PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C
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    cell.com/cell-reports/fulltext/S2211-1247(23)01052-5
  81. Sep 2023
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMT-562, a novel HER3-targeting antibody drug conjugate, demonstrates a potential to broaden therapeutic opportunities for HER3-expressing tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10477830/
  83. Aug 2023
  84. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.16933
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    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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    Contrast-enhanced ultrasound imaging for monitoring the efficacy of near-infrared photoimmunotherapy
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    52.53.155.43/6d717b39cddc6e562c4d653f38b90ec6204230d2/PIIS235239642300302X-html.html
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    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
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    sciencedirect.com/science/article/pii/S1535610823002453
  88. Jul 2023
  89. 52.53.155.43 52.53.155.43
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    The combination of osimertinib with Raf inhibitor overcomes osimertinib resistance induced by KRAS amplification in EGFR-mutated lung cancer cells
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    sciencedirect.com/science/article/pii/S0014482723002707
  92. Jun 2023
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  95. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Prognostic impact of LILRB4 expression on tumor-infiltrating cells in resected non-small cell lung cancer
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    onlinelibrary.wiley.com/doi/10.1111/1759-7714.14991
  96. aacrjournals.org aacrjournals.org
    RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition
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    aacrjournals.org/cancerres/article/83/9/1490/726058/RBM10-Loss-Promotes-EGFR-Driven-Lung-Cancer-and
  97. May 2023
  98. aacrjournals.org aacrjournals.org
    Decoding the lncRNAome across diverse cellular stresses reveals core p53-effector pan-cancer suppressive lncRNAs
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    aacrjournals.org/cancerrescommun/article/3/5/842/726358/Decoding-the-lncRNAome-Across-Diverse-Cellular
  99. Apr 2023
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10109210/
  101. Mar 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical Reactivation of Attenuated Apoptotic Pathways Leads to Elimination of Osimertinib Drug-Tolerant Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10035388/
  103. Feb 2023
  104. www.sciencedirect.com www.sciencedirect.com
    Protocol for cell-type-specific tissue reconstruction in the murine lung fibrogenic microenvironment
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    sciencedirect.com/science/article/pii/S266616672200898X
  105. Dec 2022
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome Editing Is Induced in a Binary Manner in Single Human Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9722467/
  107. aacrjournals.org aacrjournals.org
    TFAP4 activates IGF2BP1 and promotes progression of non-small cell lung cancer by stabilizing TK1 expression through m6A modification
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    aacrjournals.org/mcr/article/20/12/1763/711001/TFAP4-Activates-IGF2BP1-and-Promotes-Progression
  108. Sep 2022
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pan-Cancer Analysis and Experimental Validation Identify ACOT7 as a Novel Oncogene and Potential Therapeutic Target in Lung Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9497106/
  110. Aug 2022
  111. www.sciencedirect.com www.sciencedirect.com
    Lung fibrogenic microenvironment in mouse reconstitutes human alveolar structure and lung tumor
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    sciencedirect.com/science/article/pii/S2589004222011841
  112. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cancer-associated fibroblasts in nonsmall cell lung cancer: From molecular mechanisms to clinical implications
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34127
  113. Jul 2022
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EGFR inhibition enhances the cellular uptake and antitumor-activity of the HER3 antibody drug conjugate HER3-DXd
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  115. Jun 2022
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  126. Sep 2021
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  128. Aug 2021
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  143. Sep 2020
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