65 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
    1
    1. scibot 14 May 2024
      RV-101

      DOI: 10.1016/j.cell.2024.04.023

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    sciencedirect.com/science/article/pii/S0092867424004483
  3. Apr 2024
  4. www.sciencedirect.com www.sciencedirect.com
    14-3-3 binding motif phosphorylation disrupts Hdac4-organized condensates to stimulate cardiac reprogramming
    1
    1. scibot 05 Apr 2024
      RV-101

      DOI: 10.1016/j.celrep.2024.114054

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    sciencedirect.com/science/article/pii/S2211124724003826
  5. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    1. scibot 03 Apr 2024
      RRID:CVCL_B488

      DOI: 10.1002/1873-3468.14862

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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14862
  6. Mar 2024
  7. www.sciencedirect.com www.sciencedirect.com
    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
    1
    1. scibot 22 Mar 2024
      Cat# RV-101

      DOI: 10.1016/j.celrep.2024.113975

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    sciencedirect.com/science/article/pii/S2211124724003036
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation
    1
    1. scibot 22 Mar 2024
      RRID:CVCL_B488

      DOI: 10.7554/eLife.92873

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    ncbi.nlm.nih.gov/pmc/articles/PMC10948148/
  9. www.sciencedirect.com www.sciencedirect.com
    Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
    3
    1. scibot 15 Mar 2024
      RRID:CVCL_B488

      DOI: 10.1016/j.ccell.2024.02.016

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    2. scibot 15 Mar 2024
      RRID:CVCL_B488

      DOI: 10.1016/j.ccell.2024.02.016

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    3. scibot 15 Mar 2024
      RRID:CVCL_B488

      DOI: 10.1016/j.ccell.2024.02.016

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    sciencedirect.com/science/article/pii/S1535610824000606
  10. Feb 2024
  11. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 27 Feb 2024
      RRID: CVCL_B488

      DOI: 10.1002/1878-0261.13603

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13603
  12. www.sciencedirect.com www.sciencedirect.com
    Protocol to generate traceable CAR T cells for syngeneic mouse cancer models
    1
    1. scibot 23 Feb 2024
      RRID:CVCL_B488

      DOI: 10.1016/j.xpro.2024.102898

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    sciencedirect.com/science/article/pii/S2666166724000637
  13. www.sciencedirect.com www.sciencedirect.com
    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
    2
    1. scibot 14 Feb 2024
      RRID:CVCL_B488

      DOI: 10.1016/j.immuni.2024.01.011

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    2. scibot 14 Feb 2024
      RRID:CVCL_B488

      DOI: 10.1016/j.immuni.2024.01.011

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    sciencedirect.com/science/article/pii/S1074761324000360
  14. Dec 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANGPTL2‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion
    1
    1. scibot 15 Dec 2023
      RRID:CVCL_B488

      DOI: 10.1002/1878-0261.13490

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    ncbi.nlm.nih.gov/pmc/articles/PMC10701769/
  16. Sep 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
    1
    1. scibot 23 Sep 2023
      RRID:CVCL_B488

      DOI: 10.1016/j.isci.2023.107819

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    ncbi.nlm.nih.gov/pmc/articles/PMC10509304/
  18. www.sciencedirect.com www.sciencedirect.com
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
    1
    1. scibot 16 Sep 2023
      RRID:CVCL_B488

      DOI: 10.1016/j.celrep.2023.113098

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    sciencedirect.com/science/article/pii/S2211124723011099
  19. May 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The C10orf76–PI4KB axis orchestrates CERT-mediated ceramide trafficking to the distal Golgi
    1
    1. scibot 21 May 2023
      RRID:CVCL_B488

      DOI: 10.1083/jcb.202111069

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    ncbi.nlm.nih.gov/pmc/articles/PMC10192306/
  21. www.sciencedirect.com www.sciencedirect.com
    cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
    1
    1. scibot 11 May 2023
      RRID:CVCL_B488

      DOI: 10.1016/j.immuni.2023.04.005

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    sciencedirect.com/science/article/pii/S1074761323001735
  22. Feb 2023
  23. www.sciencedirect.com www.sciencedirect.com
    PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
    1
    1. scibot 23 Feb 2023
      RRID:CVCL_B488

      DOI: 10.1016/j.cmet.2023.01.010

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    sciencedirect.com/science/article/pii/S1550413123000104
  24. www.sciencedirect.com www.sciencedirect.com
    A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia
    1
    1. scibot 10 Feb 2023
      RRID:CVCL_B488

      DOI: 10.1016/j.celrep.2023.112099

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    sciencedirect.com/science/article/pii/S2211124723001109
  25. Jan 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes
    1
    1. scibot 28 Jan 2023
      RRID:CVCL_B488

      DOI: 10.1016/j.immuni.2022.12.007

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    sciencedirect.com/science/article/pii/S1074761322006434
  27. www.science.org www.science.org
    Anti–PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases
    1
    1. scibot 19 Jan 2023
      RRID:CVCL_B488

      DOI: 10.1126/sciimmunol.add4947

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    science.org/doi/10.1126/sciimmunol.add4947
  28. Oct 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Cross-lineage potential of Ascl1 uncovered by comparing diverse reprogramming regulatomes
    1
    1. scibot 07 Oct 2022
      RV-101

      DOI: 10.1016/j.stem.2022.09.006

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    sciencedirect.com/science/article/pii/S1934590922003836
  30. Jul 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells
    1
    1. scibot 13 Jul 2022
      RRID:CVCL_B488

      DOI: 10.1016/j.devcel.2022.06.006

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    sciencedirect.com/science/article/pii/S1534580722004464
  32. May 2022
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A somatic mutation in moesin drives progression into acute myeloid leukemia
    1
    1. scibot 11 May 2022
      RRID:CVCL_B488

      DOI: 10.1126/sciadv.abm9987

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    ncbi.nlm.nih.gov/pmc/articles/PMC9020775/
  34. Apr 2022
  35. www.science.org www.science.org
    A somatic mutation in moesin drives progression into acute myeloid leukemia
    1
    1. scibot 30 Apr 2022
      RRID:CVCL_B488

      DOI: 10.1126/sciadv.abm9987

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    science.org/doi/full/10.1126/sciadv.abm9987
  36. www.sciencedirect.com www.sciencedirect.com
    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
    1
    1. scibot 14 Apr 2022
      RRID:CVCL_B488

      DOI: 10.1016/j.celrep.2022.110636

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    sciencedirect.com/science/article/pii/S2211124722003886
  37. www.sciencedirect.com www.sciencedirect.com
    Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function
    1
    1. scibot 13 Apr 2022
      RRID:CVCL_B488

      DOI: 10.1016/j.ccell.2022.03.006

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    sciencedirect.com/science/article/pii/S1535610822001210
  38. www.sciencedirect.com www.sciencedirect.com
    Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
    1
    1. scibot 13 Apr 2022
      RRID:CVCL_B488

      DOI: 10.1016/j.immuni.2022.03.013

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    sciencedirect.com/science/article/pii/S1074761322001364
  39. www.sciencedirect.com www.sciencedirect.com
    CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming
    1
    1. scibot 07 Apr 2022
      RRID:CVCL_B488

      DOI: 10.1016/j.celrep.2022.110626

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    sciencedirect.com/science/article/pii/S2211124722003746
  40. Mar 2022
  41. www.sciencedirect.com www.sciencedirect.com
    RORγt phosphorylation protects against T cell-mediated inflammation
    1
    1. scibot 16 Mar 2022
      Cell Biolabs, Inc.Cat# RV-101

      DOI: 10.1016/j.celrep.2022.110520

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      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S221112472200256X
  42. Jan 2022
  43. www.sciencedirect.com www.sciencedirect.com
    A biomimetic hydrogel culture system to facilitate cardiac reprogramming
    1
    1. scibot 26 Jan 2022
      Cell BiolabsCat# RV-101

      DOI: 10.1016/j.xpro.2022.101122

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    sciencedirect.com/science/article/pii/S2666166722000028
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua
    1
    1. scibot 07 Jan 2022
      RRID:CVCL_B488

      DOI: 10.7554/eLife.71769

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    ncbi.nlm.nih.gov/pmc/articles/PMC8700290/
  45. Dec 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells
    1
    1. scibot 21 Dec 2021
      RRID:CVCL_B488

      DOI: 10.1016/j.immuni.2021.11.017

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    sciencedirect.com/science/article/pii/S1074761321005094
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted therapy to β3 integrin reduces chemoresistance in breast cancer bone metastases
    1
    1. scibot 02 Dec 2021
      RRID:CVCL_B488

      DOI: 10.1158/1535-7163.MCT-20-0931

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    ncbi.nlm.nih.gov/pmc/articles/PMC8442608/
  48. Nov 2021
  49. www.sciencedirect.com www.sciencedirect.com
    MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function
    1
    1. scibot 12 Nov 2021
      RRID:CVCL_B488

      DOI: 10.1016/j.immuni.2021.10.011

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    sciencedirect.com/science/article/pii/S1074761321004489
  50. www.sciencedirect.com www.sciencedirect.com
    The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age
    1
    1. scibot 10 Nov 2021
      CVCL_B488

      DOI: 10.1016/j.celrep.2021.109981

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    sciencedirect.com/science/article/pii/S2211124721014601
  51. Sep 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
    1
    1. scibot 04 Sep 2021
      RRID:CVCL_B488

      DOI: 10.7554/eLife.65872

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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  53. Aug 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice
    1
    1. scibot 17 Aug 2021
      RRID:CVCL_B488

      DOI: 10.7554/eLife.68227

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    ncbi.nlm.nih.gov/pmc/articles/PMC8360648/
  55. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
    1
    1. scibot 15 Aug 2021
      RRID:CVCL_B488

      DOI: 10.7554/eLife.64148

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    elifesciences.org/articles/64148
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Native adiponectin in serum binds to mammalian cells expressing T-cadherin, but not AdipoRs or calreticulin
    1
    1. scibot 01 Aug 2021
      RRID:CVCL_B488

      DOI: 10.7554/eLife.48675

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      RRIDCUR:Validated RRID:CVCL_B488
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    ncbi.nlm.nih.gov/pmc/articles/PMC6822988/
  57. Jul 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency
    1
    1. scibot 31 Jul 2021
      Plat-E cells

      DOI: 10.1016/j.celrep.2019.10.044

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      Curator: @ethanbadger

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      RRID:CVCL_B488 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124719313580
  59. www.sciencedirect.com www.sciencedirect.com
    Activity-Dependent Secretion of Synaptic Organizer Cbln1 from Lysosomes in Granule Cell Axons
    2
    1. scibot 29 Jul 2021
      RRID:CVCL_B488

      DOI: 10.1016/j.neuron.2019.03.044

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    2. scibot 28 Jul 2021
      RRID:CVCL_B488

      DOI: 10.1016/j.neuron.2019.03.044

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    sciencedirect.com/science/article/pii/S0896627319303332
  60. Jun 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Toll-like receptor 2 induces pathogenicity in Th17 cells and reveals a role for IPCEF in regulating Th17 cell migration
    1
    1. scibot 30 Jun 2021
      RRID:CVCL_B488

      DOI: 10.1016/j.celrep.2021.109303

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    sciencedirect.com/science/article/pii/S2211124721006793
  62. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms
    1
    1. scibot 29 Jun 2021
      RRID:CVCL_B488

      DOI: 10.1158/2159-8290.CD-20-1353

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    cancerdiscovery.aacrjournals.org/content/11/6/1398
  63. Apr 2021
  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Long‐term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges
    1
    1. scibot 01 Apr 2021
      RRID:CVCL_B488

      DOI: 10.1002/ijc.33523

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33523
  65. Feb 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency
    1
    1. scibot 28 Feb 2021
      RRID:CVCL_B488

      DOI: 10.1016/j.molcel.2020.11.045

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    sciencedirect.com/science/article/pii/S109727652030887X
  67. elifesciences.org elifesciences.org
    Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis
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    1. scibot 27 Feb 2021
      RRID:CVCL_B488

      DOI: 10.7554/eLife.59659

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    elifesciences.org/articles/59659
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy
    1
    1. scibot 26 Feb 2021
      RRID:CVCL_B488

      DOI: 10.1016/j.immuni.2020.04.007

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    ncbi.nlm.nih.gov/pmc/articles/PMC7784612/
  69. www.cell.com www.cell.com
    Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade
    1
    1. scibot 24 Feb 2021
      RRID:CVCL_B488

      DOI: 10.1016/j.ccell.2020.11.005

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    cell.com/cancer-cell/abstract/S1535-6108(20)30597-3
  70. Nov 2020
  71. www.sciencedirect.com www.sciencedirect.com
    Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
    1
    1. scibot 07 Nov 2020
      RRID:CVCL_B488

      DOI: 10.1016/j.celrep.2020.108333

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    sciencedirect.com/science/article/pii/S221112472031322X
  72. Oct 2020
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Critical role of WNK1 in MYC-dependent early mouse thymocyte development
    1
    1. scibot 31 Oct 2020
      RRID:CVCL_B488

      DOI: 10.7554/eLife.56934

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    ncbi.nlm.nih.gov/pmc/articles/PMC7591260/
  74. Sep 2020
  75. www.sciencedirect.com www.sciencedirect.com
    Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics
    1
    1. scibot 13 Sep 2020
      RRID:CVCL_B488

      DOI: 10.1016/j.immuni.2020.01.018

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    sciencedirect.com/science/article/pii/S1074761320300467
  76. elifesciences.org elifesciences.org
    Differential expression of Lutheran/BCAM regulates biliary tissue remodeling in ductular reaction during liver regeneration
    1
    1. scibot 11 Sep 2020
      RRID:CVCL_B488

      DOI: 10.7554/eLife.36572

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    elifesciences.org/articles/36572
  77. www.sciencedirect.com www.sciencedirect.com
    Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
    1
    1. scibot 03 Sep 2020
      RRID: CVCL_B488

      DOI: 10.1016/j.molcel.2020.01.008

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    sciencedirect.com/science/article/pii/S1097276520300083
  78. www.sciencedirect.com www.sciencedirect.com
    Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
    1
    1. scibot 03 Sep 2020
      PlatE

      DOI: 10.1016/j.celrep.2020.02.007

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    sciencedirect.com/science/article/pii/S2211124720301613
  79. Jan 2020
  80. www.sciencedirect.com www.sciencedirect.com
    Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_B488

      DOI: 10.1016/j.ccell.2019.02.003

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    sciencedirect.com/science/article/pii/S1535610819300984
  81. www.sciencedirect.com www.sciencedirect.com
    A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis
    1
    1. scibot 12 Jan 2020
      RRID:CVCL_B488

      DOI: 10.1016/j.ccell.2018.10.004

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    sciencedirect.com/science/article/pii/S1535610818304707
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:CVCL_B488

      DOI: 10.7554/eLife.41627

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    ncbi.nlm.nih.gov/pmc/articles/PMC6435319/
  83. Nov 2018
  84. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_B488

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    sciencedirect.com/science/article/pii/S1934590918304363
  85. www.sciencedirect.com www.sciencedirect.com
    Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_B488

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    sciencedirect.com/science/article/pii/S1934590918304016
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_B488

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    ncbi.nlm.nih.gov/pmc/articles/PMC6107333/
  87. elifesciences.org elifesciences.org
    Untitled document
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      RRID:CVCL_B488

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    elifesciences.org/articles/32893
  88. Nov 2017
  89. www.sciencedirect.com www.sciencedirect.com
    RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions
    1
    1. scibot 08 Nov 2017
      CVCL_B488

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    sciencedirect.com/science/article/pii/S1934590916304581
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy
    1
    1. scibot 08 Nov 2017
      CVCL_B488

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC5249261/