109 Matching Annotations
  1. Aug 2026
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    Host metadherin coordinates hepatic lipid metabolism and CD8+ T cell immunity to promote tumor progression
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    sciencedirect.com/science/article/pii/S1550413126003281
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    Surface protein profiling reveals depot-specific features of subcutaneous and visceral adipose progenitor cells
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    sciencedirect.com/science/article/pii/S2405580826003109
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cblb Gene Editing in T Cells Sustains Expansion and Immunogenic CAR T Tumor Killing Under Chronic Antigenic Stimulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13464884/
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    Increased signaling of the Neanderthal growth hormone receptor
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    sciencedirect.com/science/article/pii/S0960982226008900
  6. Jul 2026
  7. aacrjournals.org aacrjournals.org
    FLT3-ITD Induces CMTM6 and Enhances Immune Escape in Acute Myeloid Leukemia
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    aacrjournals.org/cancerres/article/86/2/367/771679/FLT3-ITD-Induces-CMTM6-and-Enhances-Immune-Escape
  8. aacrjournals.org aacrjournals.org
    Loss of SETD8 Impairs Mitochondrial Homeostasis to Suppress Leukemia Stem Cell Function in t(8;21) Acute Myeloid Leukemia
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    aacrjournals.org/cancerres/article/85/21/4122/766740/Loss-of-SETD8-Impairs-Mitochondrial-Homeostasis-to
  9. Jun 2026
  10. www.sciencedirect.com www.sciencedirect.com
    Naive CD4+ T cells synthesize a hyaluronan-rich glycocalyx that is diminished following activation
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    sciencedirect.com/science/article/pii/S2589004226017827
  11. Apr 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    E-cadherin expression promotes tumor growth via KLRG1-dependent pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC13108842/
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70550
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    FOXF1/2 establish a senescence-specific enhancer landscape to activate the pro-inflammatory senescence-associated secretory phenotype
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    sciencedirect.com/science/article/pii/S1097276526001966
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NR2F6 deletion revives CAR-T cell function and induces antigen-agnostic immune memory in solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13065922/
  16. Mar 2026
  17. www.sciencedirect.com www.sciencedirect.com
    Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation
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    sciencedirect.com/science/article/pii/S1074761326001160
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    Gut microbiota-derived indole-3-lactic acid suppresses anti-PD-1 efficacy in esophageal squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S1931312826000879
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    Tissue and CD4 T cell subset dependence on the amino acid transporter SLC38A1
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    sciencedirect.com/science/article/pii/S1550413126000859
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    β-hydroxybutyrate enhances the metabolic fitness of CAR T cells in cancer
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    sciencedirect.com/science/article/pii/S0092867426001698
  21. Feb 2026
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    Fungal-derived cellobiose metabolic pathway fuels T cells to bypass intratumoral glucose competition
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    sciencedirect.com/science/article/pii/S0092867426001029
  23. Jan 2026
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    Myomaker and ether lipids cooperate to promote fusion-competent membrane states
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    sciencedirect.com/science/article/pii/S2211124725016729
  25. Dec 2025
  26. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225025647-main-html.html
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    54.241.53.176/6616620d4f1dc598cdc85a941c81195110b67c2e/1-s2.0-S2589004225025647-main-html.html
  27. Oct 2025
  28. www.science.org www.science.org
    T cell cholesterol transport links intestinal immune responses to dietary lipid absorption
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    science.org/doi/10.1126/science.adt4169
  29. www.biorxiv.org www.biorxiv.org
    The V617F mutation in JAK2 renders myeloid cells more sensitive to IL-6-mediated gp130 signaling
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    biorxiv.org/content/10.1101/2025.10.10.681590v1
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lung cancer–intrinsic SOX2 expression mediates resistance to checkpoint blockade therapy by inducing Treg cell–dependent CD8+ T-cell exclusion
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964848/
  31. Aug 2025
  32. 52.53.155.43 52.53.155.43
    2025.08.13.669552v1.full-html.html
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  33. www.nature.com www.nature.com
    Unraveling the impact of crizotinib to promote megakaryopoiesis for alleviating thrombocytopenia in myelodysplastic neoplasms
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    nature.com/articles/s41375-025-02729-w
  34. Jul 2025
  35. www.nature.com www.nature.com
    Manufacturing of CRISPR-edited primary mouse CAR T cells for cancer immunotherapy
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    nature.com/articles/s41596-025-01208-x
  36. May 2025
  37. www.sciencedirect.com www.sciencedirect.com
    Protocol for CRISPR-mediated deletion of cis-regulatory element in murine Th17 cells for in vivo assessment of effector function
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    sciencedirect.com/science/article/pii/S2666166725002370
  38. link.springer.com link.springer.com
    Enhancing mesothelin CAR T cell therapy for pancreatic cancer with an oncolytic herpes virus boosting CAR target antigen expression
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    link.springer.com/article/10.1007/s00262-025-04039-7
  39. Apr 2025
  40. www.sciencedirect.com www.sciencedirect.com
    Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
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    sciencedirect.com/science/article/pii/S0092867425002909
  41. Mar 2025
  42. www.sciencedirect.com www.sciencedirect.com
    Compact transcription factor cassettes generate functional, engraftable motor neurons by direct conversion
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    sciencedirect.com/science/article/pii/S2405471225000390
  43. www.sciencedirect.com www.sciencedirect.com
    Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia
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    sciencedirect.com/science/article/pii/S1535610825000601
  44. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial fusion and cristae reorganization facilitate acquisition of cardiomyocyte identity during reprogramming of murine fibroblasts
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    sciencedirect.com/science/article/pii/S2211124725001482
  45. Feb 2025
  46. www.sciencedirect.com www.sciencedirect.com
    MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling
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    sciencedirect.com/science/article/pii/S1550413125000178
  47. www.sciencedirect.com www.sciencedirect.com
    A microRNA-regulated transcriptional state defines intratumoral CD8+ T cells that respond to immunotherapy
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    sciencedirect.com/science/article/pii/S2211124725000725
  48. Jan 2025
  49. www.science.org www.science.org
    Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis
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    science.org/doi/10.1126/sciimmunol.adl4909
  50. www.sciencedirect.com www.sciencedirect.com
    Protocol for in vitro observation of HDAC4 condensation during induced cardiac reprogramming
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    sciencedirect.com/science/article/pii/S2666166724006889
  51. Dec 2024
  52. www.sciencedirect.com www.sciencedirect.com
    Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis
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    sciencedirect.com/science/article/pii/S1074761324005211
  53. Nov 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection
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    sciencedirect.com/science/article/pii/S2211124724013020
  55. elifesciences.org elifesciences.org
    PD-1 negatively regulates helper T cell differentiation into Th2
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    elifesciences.org/reviewed-preprints/100879
  56. Oct 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405138/
  58. Sep 2024
  59. www.sciencedirect.com www.sciencedirect.com
    Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy
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    sciencedirect.com/science/article/pii/S0092867424009565
  60. www.biorxiv.org www.biorxiv.org
    PD-1 negatively regulates helper T cell differentiation into Th2
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    biorxiv.org/content/10.1101/2024.07.26.605269v1
  61. Aug 2024
  62. www.cell.com www.cell.com
    SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
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    cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
  63. Jul 2024
  64. www.sciencedirect.com www.sciencedirect.com
    Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers
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    sciencedirect.com/science/article/pii/S2211124724008258
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    BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion
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    sciencedirect.com/science/article/pii/S2211124724007319
  66. May 2024
  67. aacrjournals.org aacrjournals.org
    One CD4+TCR and one CD8+TCR targeting autochthonous neoantigens are essential and sufficient for tumor eradication
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    aacrjournals.org/clincancerres/article/30/8/1642/742133/One-CD4-TCR-and-One-CD8-TCR-Targeting
  68. www.sciencedirect.com www.sciencedirect.com
    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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    sciencedirect.com/science/article/pii/S0092867424004483
  69. Apr 2024
  70. www.sciencedirect.com www.sciencedirect.com
    14-3-3 binding motif phosphorylation disrupts Hdac4-organized condensates to stimulate cardiac reprogramming
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    sciencedirect.com/science/article/pii/S2211124724003826
  71. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14862
  72. Mar 2024
  73. www.sciencedirect.com www.sciencedirect.com
    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
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    sciencedirect.com/science/article/pii/S2211124724003036
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10948148/
  75. www.sciencedirect.com www.sciencedirect.com
    Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
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    sciencedirect.com/science/article/pii/S1535610824000606
  76. Feb 2024
  77. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13603
  78. www.sciencedirect.com www.sciencedirect.com
    Protocol to generate traceable CAR T cells for syngeneic mouse cancer models
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    sciencedirect.com/science/article/pii/S2666166724000637
  79. www.sciencedirect.com www.sciencedirect.com
    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
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    sciencedirect.com/science/article/pii/S1074761324000360
  80. Dec 2023
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANGPTL2‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10701769/
  82. Sep 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
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    ncbi.nlm.nih.gov/pmc/articles/PMC10509304/
  84. www.sciencedirect.com www.sciencedirect.com
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
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    sciencedirect.com/science/article/pii/S2211124723011099
  85. May 2023
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The C10orf76–PI4KB axis orchestrates CERT-mediated ceramide trafficking to the distal Golgi
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    ncbi.nlm.nih.gov/pmc/articles/PMC10192306/
  87. www.sciencedirect.com www.sciencedirect.com
    cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1074761323001735
  88. Feb 2023
  89. www.sciencedirect.com www.sciencedirect.com
    PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
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    sciencedirect.com/science/article/pii/S1550413123000104
  90. www.sciencedirect.com www.sciencedirect.com
    A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S2211124723001109
  91. Jan 2023
  92. www.sciencedirect.com www.sciencedirect.com
    Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes
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    sciencedirect.com/science/article/pii/S1074761322006434
  93. www.science.org www.science.org
    Anti–PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases
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    science.org/doi/10.1126/sciimmunol.add4947
  94. Oct 2022
  95. www.sciencedirect.com www.sciencedirect.com
    Cross-lineage potential of Ascl1 uncovered by comparing diverse reprogramming regulatomes
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    sciencedirect.com/science/article/pii/S1934590922003836
  96. Jul 2022
  97. www.sciencedirect.com www.sciencedirect.com
    Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells
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    sciencedirect.com/science/article/pii/S1534580722004464
  98. May 2022
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A somatic mutation in moesin drives progression into acute myeloid leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9020775/
  100. Apr 2022
  101. www.science.org www.science.org
    A somatic mutation in moesin drives progression into acute myeloid leukemia
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    science.org/doi/full/10.1126/sciadv.abm9987
  102. www.sciencedirect.com www.sciencedirect.com
    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    sciencedirect.com/science/article/pii/S2211124722003886
  103. www.sciencedirect.com www.sciencedirect.com
    Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function
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    sciencedirect.com/science/article/pii/S1535610822001210
  104. www.sciencedirect.com www.sciencedirect.com
    Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
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    sciencedirect.com/science/article/pii/S1074761322001364
  105. www.sciencedirect.com www.sciencedirect.com
    CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming
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    sciencedirect.com/science/article/pii/S2211124722003746
  106. Mar 2022
  107. www.sciencedirect.com www.sciencedirect.com
    RORγt phosphorylation protects against T cell-mediated inflammation
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    sciencedirect.com/science/article/pii/S221112472200256X
  108. Jan 2022
  109. www.sciencedirect.com www.sciencedirect.com
    A biomimetic hydrogel culture system to facilitate cardiac reprogramming
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    sciencedirect.com/science/article/pii/S2666166722000028
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua
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    ncbi.nlm.nih.gov/pmc/articles/PMC8700290/
  111. Dec 2021
  112. www.sciencedirect.com www.sciencedirect.com
    Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells
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    sciencedirect.com/science/article/pii/S1074761321005094
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted therapy to β3 integrin reduces chemoresistance in breast cancer bone metastases
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    ncbi.nlm.nih.gov/pmc/articles/PMC8442608/
  114. Nov 2021
  115. www.sciencedirect.com www.sciencedirect.com
    MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function
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    sciencedirect.com/science/article/pii/S1074761321004489
  116. www.sciencedirect.com www.sciencedirect.com
    The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age
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    sciencedirect.com/science/article/pii/S2211124721014601
  117. Sep 2021
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  119. Aug 2021
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC8360648/
  121. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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    elifesciences.org/articles/64148
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Native adiponectin in serum binds to mammalian cells expressing T-cadherin, but not AdipoRs or calreticulin
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    ncbi.nlm.nih.gov/pmc/articles/PMC6822988/
  123. Jul 2021
  124. www.sciencedirect.com www.sciencedirect.com
    Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency
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    sciencedirect.com/science/article/pii/S2211124719313580
  125. www.sciencedirect.com www.sciencedirect.com
    Activity-Dependent Secretion of Synaptic Organizer Cbln1 from Lysosomes in Granule Cell Axons
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    sciencedirect.com/science/article/pii/S0896627319303332
  126. Jun 2021
  127. www.sciencedirect.com www.sciencedirect.com
    Toll-like receptor 2 induces pathogenicity in Th17 cells and reveals a role for IPCEF in regulating Th17 cell migration
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  129. Apr 2021
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  131. Feb 2021
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  135. www.cell.com www.cell.com
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  136. Nov 2020
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  138. Oct 2020
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  140. Sep 2020
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  149. Nov 2018
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  154. Nov 2017
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