Hypothesis

19 Matching Annotations

May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis

1
1. scibot 09 May 2026
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1126/sciadv.adv1434
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC13142706/
Apr 2026
www.sciencedirect.com www.sciencedirect.com

SARM1 executes neuronal parthanatos and promotes excitotoxic cell death

1
1. scibot 17 Apr 2026
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1016/j.neuron.2026.03.027
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

sciencedirect.com/science/article/pii/S0896627326002187
www.biorxiv.org www.biorxiv.org

One-step induction of human GABAergic neurons promotes presynaptic development & synapse maturation

1
1. scibot 09 Apr 2026
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1101/2025.06.30.662293
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

biorxiv.org/content/10.1101/2025.06.30.662293v3
Feb 2026
www.sciencedirect.com www.sciencedirect.com

comBO: A combined human bone and lympho-myeloid bone marrow organoid for preclinical modeling of hematopoietic disorders

1
1. scibot 24 Feb 2026
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1016/j.stem.2026.01.010
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

sciencedirect.com/science/article/pii/S1934590926000330
www.sciencedirect.com www.sciencedirect.com

Insulin-like growth factor signaling regulates zebrafish lymphatic-vessel development

1
1. scibot 20 Feb 2026
  
  in Public
  
  Jackson LaboratoryJIPSC001000
  
  DOI: 10.1016/j.celrep.2026.116971
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

sciencedirect.com/science/article/pii/S2211124726000495
Jan 2026
www.biorxiv.org www.biorxiv.org

Agomelatine drives sex-specific neuroprotection and reduced pathology in rat and human Alzheimer’s models

1
1. scibot 27 Jan 2026
  
  in Public
  
  JIPSC001000
  
  DOI: 10.64898/2026.01.17.700104
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

biorxiv.org/content/10.64898/2026.01.17.700104v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Growth factor supplementation modulates survival, morphology, and network activity of neurogenin-2 induced human neurons

1
1. scibot 22 Jan 2026
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1038/s41598-025-31868-4
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12808180/
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

MeCP2 regulates telencephalic development in human cerebral organoids

1
1. scibot 16 Dec 2025
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1016/j.celrep.2025.116670
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

sciencedirect.com:5037/science/article/pii/S2211124725014421
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PCM1 coordinates centrosome asymmetry with polarized endosome dynamics to regulate daughter cell fate

1
1. scibot 02 Dec 2025
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1038/s41467-025-65756-2
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12663461/
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Forebrain assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects

1
1. scibot 22 Jul 2025
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1016/j.neuron.2025.06.017
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

sciencedirect.com/science/article/pii/S0896627325004751
www.sciencedirect.com www.sciencedirect.com

Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4

1
1. scibot 15 Jul 2025
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1016/j.celrep.2025.115961
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725007326
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Protocol for generating NGN2 iPSC lines and large-scale human neuron production

1
1. scibot 06 Mar 2025
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1016/j.xpro.2025.103654
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

sciencedirect.com/science/article/pii/S2666166725000607
Feb 2025
52.53.155.43 52.53.155.43

Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation

1
1. scibot 06 Feb 2025
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1101/2024.10.14.618089
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

52.53.155.43/01dd9728947fbe4affbd9309aaacf50825c24057/2024.10.14.618089.full-html.html
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Protocol for live imaging of axonal transport in iPSC-derived iNeurons

1
1. scibot 30 Jan 2025
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1016/j.xpro.2024.103556
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11772938/
www.sciencedirect.com www.sciencedirect.com

CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions

1
1. scibot 16 Jan 2025
  
  in Public
  
  Jackson LaboratoryJIPSC001000
  
  DOI: 10.1016/j.neuron.2024.12.016
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

sciencedirect.com/science/article/pii/S0896627324009152
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Fully defined NGN2 neuron protocol reveals diverse signatures of neuronal maturation

1
1. scibot 10 Sep 2024
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1016/j.crmeth.2024.100858
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

sciencedirect.com/science/article/pii/S2667237524002364
Aug 2024
www.sciencedirect.com www.sciencedirect.com

The V-ATPase/ATG16L1 axis is controlled by the V1H subunit

1
1. scibot 01 Aug 2024
  
  in Public
  
  Strain: 765000
  
  DOI: 10.1016/j.molcel.2024.07.003
  
  Resource: CVCL_B5P3
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

sciencedirect.com/science/article/pii/S1097276524005793
May 2024
www.biorxiv.org www.biorxiv.org

Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines

1
1. scibot 30 May 2024
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1101/2024.05.21.589311
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @mzhang007
  
  SciCrunch record: RRID:CVCL_B5P3
  
  What is this?
  
  RRIDCUR:Unresolved DOI:10.1101/2024.05.21.589311 RRID:CVCL_B5P3
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RRID:CVCL_B5P3

RRIDCUR:Unresolved

DOI:10.1101/2024.05.21.589311

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scibot

URL

biorxiv.org/content/10.1101/2024.05.21.589311v1
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors

1
1. scibot 27 Mar 2024
  
  in Public
  
  RRID:CVCL_B5P3
  
  DOI: 10.1083/jcb.202307092
  
  Resource: (RRID:CVCL_B5P3)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_B5P3
  
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  RRID:CVCL_B5P3
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RRID:CVCL_B5P3

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10959120/