38 Matching Annotations
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    Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth
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    sciencedirect.com/science/article/pii/S009286742601010X
  3. Sep 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-Polio Enterovirus A71 and D68 Infection of Human Neuromuscular Organoids Reveals Distinct Mechanisms of Neuromuscular Impairment
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    pmc.ncbi.nlm.nih.gov/articles/PMC13517452/
  5. May 2026
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    Protocol for validating drug efficacy and safety in scalable 96-well platforms of human cortical organoids and melanoma brain metastases
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    sciencedirect.com/science/article/pii/S2666166726002212
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    Modeling Synaptic Maturation From Growth Cone to Synapse in Human Organoids
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70458
  8. Apr 2026
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    Microglia cause HIV-induced transcriptional and metabolic changes in human neural organoids
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    nature.com/articles/s42003-026-09864-9
  10. Mar 2026
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    Targeting PGAM5-driven mitochondrial integrated stress response slows ALS progression across subtypes
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    sciencedirect.com/science/article/pii/S0896627326000863
  12. Feb 2026
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    Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles
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    sciencedirect.com/science/article/pii/S2667237525003315
  14. Jan 2026
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    Brain capillary endothelial-like cells show altered barrier functionality and reduced transport of amyloid β in late-onset Alzheimer disease
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    pubmed.ncbi.nlm.nih.gov/41566484/
  16. Nov 2025
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    Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs
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    sciencedirect.com/science/article/pii/S2667237525002723
  18. Sep 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Addressing neuroinflammation in human induced pluripotent stem cell-derived central nervous system neurospheroids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12392327/
  20. Jul 2025
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    Effect of antivirals on clinical and lab-adapted human cytomegalovirus strains using induced Pluripotent Stem Cell-derived human neural models
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    sciencedirect.com/science/article/pii/S0166354225001597
  22. Jun 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In Vitro Comparison of Two Python‐Based Programs for the Automated Analysis of Tight‐Junction Phenotype in Brain Endothelium During Bacterial Infection
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    Differentiation of Brain Mural Cells from Human Pluripotent Stem Cell-Derived Neural Crest by Activation of Notch3 Signaling
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    link.springer.com/protocol/10.1007/978-1-0716-4474-4_2
  25. Jan 2025
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    Glucose Transporter 1 Deficiency Impairs Glucose Metabolism and Barrier Induction in Human Induced Pluripotent Stem Cell-Derived Astrocytes
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    onlinelibrary.wiley.com/doi/10.1002/jcp.31523
  27. Dec 2024
  28. www.cell.com www.cell.com
    Heparan sulfate regulates the fate decisions of human pluripotent stem cells
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    cell.com/stem-cell-reports/abstract/S2213-6711(24)00328-X
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    Targeted Proteomics for Absolute Quantification of Glucose Transporter 1 in Mammalian Brain Cells Using Liquid Chromatography-Mass Spectrometry
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    sciencedirect.com/science/article/pii/S2772391724000859
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    Impacts of APOE-ε4 and exercise training on brain microvascular endothelial cell barrier function and metabolism
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    sciencedirect.com/science/article/pii/S2352396424005231
  31. Aug 2024
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    physiology.org/doi/abs/10.1152/ajpcell.00116.2017
  33. Apr 2024
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    Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
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    sciencedirect.com/science/article/pii/S1934590924000948
  35. Jul 2023
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    Ketone bodies supplementation restores the barrier function, induces a metabolic switch, and elicits beta-hydroxybutyrate diffusion across a monolayer of iPSC-derived brain microvascular endothelial cells
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    sciencedirect.com/science/article/abs/pii/S0026286223001115
  37. Sep 2022
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    An in vitro model of glucose transporter 1 deficiency syndrome at the blood-brain barrier using induced pluripotent stem cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15684
  39. Jun 2022
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    Intrinsic antiviral immunity of barrier cells revealed by an iPSC-derived blood-brain barrier cellular model
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    sciencedirect.com/science/article/pii/S221112472200660X
  41. Jan 2022
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    Abeta Peptides Disrupt the Barrier Integrity and Glucose Metabolism of Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells
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    sciencedirect.com/science/article/pii/S0161813X22000158
  43. Dec 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8664294/
  45. Aug 2021
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14040
  47. Jun 2021
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    Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions
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    sciencedirect.com/science/article/pii/S2666166721002707
  49. Feb 2021
  50. pubs.acs.org pubs.acs.org
    An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening
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    pubs.acs.org/doi/full/10.1021/acsptsci.0c00077
  51. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Unveiling dynamic metabolic signatures in human induced pluripotent and neural stem cells
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    pubmed.ncbi.nlm.nih.gov/32298259/
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model
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    onlinelibrary.wiley.com/doi/full/10.1111/jne.12931
  53. Dec 2020
  54. www.nature.com www.nature.com
    Generation and long-term culture of advanced cerebral organoids for studying later stages of neural development
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    nature.com/articles/s41596-020-00433-w
  55. Sep 2020
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyaluronan impairs the barrier integrity of brain microvascular endothelial cells through a CD44-dependent pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC6727144/
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    Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development
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    sciencedirect.com/science/article/pii/S1534580720303075
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transplantation of iPS‐derived vascular endothelial cells improves white matter ischemic damage
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14949
  59. Jan 2020
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    Effects of glyphosate and aminomethylphosphonic acid on an isogeneic model of the human blood-brain barrier
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    sciencedirect.com/science/article/pii/S0378427418319040
  61. link.springer.com link.springer.com
    Oxygen-Glucose Deprivation/Reoxygenation-Induced Barrier Disruption at the Human Blood–Brain Barrier is Partially Mediated Through the HIF-1 Pathway
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    link.springer.com/article/10.1007/s12017-019-08531-z
  62. Apr 2019
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Isogenic blood–brain barrier models based on patient‐derived stem cells display inter‐individual differences in cell maturation and functionality
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14040/full
  64. Nov 2018
  65. www.physiology.org www.physiology.org
    Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells | American Journal of Physiology-Cell Physiology
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    physiology.org/doi/full/10.1152/ajpcell.00116.2017
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    Differences in definitive endoderm induction approaches using growth factors and small molecules
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    onlinelibrary.wiley.com/doi/10.1002/jcp.26214/full