36 Matching Annotations
  1. Last 7 days
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    Protocol for validating drug efficacy and safety in scalable 96-well platforms of human cortical organoids and melanoma brain metastases
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    sciencedirect.com/science/article/pii/S2666166726002212
  3. May 2026
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Modeling Synaptic Maturation From Growth Cone to Synapse in Human Organoids
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70458
  5. Apr 2026
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    Microglia cause HIV-induced transcriptional and metabolic changes in human neural organoids
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    nature.com/articles/s42003-026-09864-9
  7. Mar 2026
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    Targeting PGAM5-driven mitochondrial integrated stress response slows ALS progression across subtypes
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    sciencedirect.com/science/article/pii/S0896627326000863
  9. Feb 2026
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    Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles
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    sciencedirect.com/science/article/pii/S2667237525003315
  11. Jan 2026
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    Brain capillary endothelial-like cells show altered barrier functionality and reduced transport of amyloid β in late-onset Alzheimer disease
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    link.springer.com/article/10.1186/s12987-025-00753-7
  13. Nov 2025
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    Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs
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    sciencedirect.com/science/article/pii/S2667237525002723
  15. Sep 2025
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    Addressing neuroinflammation in human induced pluripotent stem cell-derived central nervous system neurospheroids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12392327/
  17. Jul 2025
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    Effect of antivirals on clinical and lab-adapted human cytomegalovirus strains using induced Pluripotent Stem Cell-derived human neural models
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    sciencedirect.com/science/article/pii/S0166354225001597
  19. Jun 2025
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    In Vitro Comparison of Two Python‐Based Programs for the Automated Analysis of Tight‐Junction Phenotype in Brain Endothelium During Bacterial Infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12169080/
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    Differentiation of Brain Mural Cells from Human Pluripotent Stem Cell-Derived Neural Crest by Activation of Notch3 Signaling
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    link.springer.com/protocol/10.1007/978-1-0716-4474-4_2
  22. Jan 2025
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    Glucose Transporter 1 Deficiency Impairs Glucose Metabolism and Barrier Induction in Human Induced Pluripotent Stem Cell-Derived Astrocytes
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    onlinelibrary.wiley.com/doi/10.1002/jcp.31523
  24. Dec 2024
  25. www.cell.com www.cell.com
    Heparan sulfate regulates the fate decisions of human pluripotent stem cells
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    cell.com/stem-cell-reports/abstract/S2213-6711(24)00328-X
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    Targeted Proteomics for Absolute Quantification of Glucose Transporter 1 in Mammalian Brain Cells Using Liquid Chromatography-Mass Spectrometry
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    sciencedirect.com/science/article/pii/S2772391724000859
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    Impacts of APOE-ε4 and exercise training on brain microvascular endothelial cell barrier function and metabolism
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    sciencedirect.com/science/article/pii/S2352396424005231
  28. Aug 2024
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    Untitled document
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    physiology.org/doi/abs/10.1152/ajpcell.00116.2017
  30. Apr 2024
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    Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
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    sciencedirect.com/science/article/pii/S1934590924000948
  32. Jul 2023
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    Ketone bodies supplementation restores the barrier function, induces a metabolic switch, and elicits beta-hydroxybutyrate diffusion across a monolayer of iPSC-derived brain microvascular endothelial cells
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    sciencedirect.com/science/article/abs/pii/S0026286223001115
  34. Sep 2022
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    An in vitro model of glucose transporter 1 deficiency syndrome at the blood-brain barrier using induced pluripotent stem cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15684
  36. Jun 2022
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    Intrinsic antiviral immunity of barrier cells revealed by an iPSC-derived blood-brain barrier cellular model
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    sciencedirect.com/science/article/pii/S221112472200660X
  38. Jan 2022
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    Abeta Peptides Disrupt the Barrier Integrity and Glucose Metabolism of Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells
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    sciencedirect.com/science/article/pii/S0161813X22000158
  40. Dec 2021
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8664294/
  42. Aug 2021
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14040
  44. Jun 2021
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    Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions
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    sciencedirect.com/science/article/pii/S2666166721002707
  46. Feb 2021
  47. pubs.acs.org pubs.acs.org
    An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening
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    pubs.acs.org/doi/full/10.1021/acsptsci.0c00077
  48. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Unveiling dynamic metabolic signatures in human induced pluripotent and neural stem cells
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    pubmed.ncbi.nlm.nih.gov/32298259/
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model
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    onlinelibrary.wiley.com/doi/full/10.1111/jne.12931
  50. Dec 2020
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    Generation and long-term culture of advanced cerebral organoids for studying later stages of neural development
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    nature.com/articles/s41596-020-00433-w
  52. Sep 2020
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyaluronan impairs the barrier integrity of brain microvascular endothelial cells through a CD44-dependent pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC6727144/
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    Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development
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    sciencedirect.com/science/article/pii/S1534580720303075
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    Transplantation of iPS‐derived vascular endothelial cells improves white matter ischemic damage
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14949
  56. Jan 2020
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    Effects of glyphosate and aminomethylphosphonic acid on an isogeneic model of the human blood-brain barrier
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    sciencedirect.com/science/article/pii/S0378427418319040
  58. link.springer.com link.springer.com
    Oxygen-Glucose Deprivation/Reoxygenation-Induced Barrier Disruption at the Human Blood–Brain Barrier is Partially Mediated Through the HIF-1 Pathway
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    link.springer.com/article/10.1007/s12017-019-08531-z
  59. Apr 2019
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Isogenic blood–brain barrier models based on patient‐derived stem cells display inter‐individual differences in cell maturation and functionality
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14040/full
  61. Nov 2018
  62. www.physiology.org www.physiology.org
    Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells | American Journal of Physiology-Cell Physiology
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    physiology.org/doi/full/10.1152/ajpcell.00116.2017
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Differences in definitive endoderm induction approaches using growth factors and small molecules
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    onlinelibrary.wiley.com/doi/10.1002/jcp.26214/full