138 Matching Annotations
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    Excess intracellular lactate represses mRNA translation and tumor progression through lactate-tRNA charging
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    sciencedirect.com/science/article/pii/S1097276526005125
  3. Jul 2026
  4. watermark02.silverchair.com watermark02.silverchair.com
    noag173.pdf
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  5. aacrjournals.org aacrjournals.org
    Antibody-Mediated Targeting of Secretory Protein SCUBE3 Suppresses Cancer Progression by Inhibiting Oncogenic Signaling and Inducing Anti-tumor Immunity
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    aacrjournals.org/cancerres/article/86/5/1252/774876/Antibody-Mediated-Targeting-of-Secretory-Protein
  6. Jun 2026
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    Estradiol Reprograms Microglia to Create an Immune-Suppressed Niche Permissive to Breast Cancer Brain Metastasis
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    biorxiv.org/content/10.64898/2026.02.20.707087v1
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    Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple-Negative Breast Cancer to PD-1 Blockade
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202521541
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ACSS2 Suppresses Ferroptosis to Drive Breast Cancer Brain Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13195636/
  10. May 2026
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    Linking tumor viability and immune infiltration with dual-nucleus MRI in preclinical models
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    pmc.ncbi.nlm.nih.gov/articles/PMC13201762/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial Multiomics Analyses Reveal That Diabetes Promotes Pancreatic Cancer Progression by Stimulating Cholesterol-Induced Neutrophil Extracellular Trap Formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13176823/
  13. Apr 2026
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    A microbiota-derived bile acid overcomes antibiotic-induced hyporesponsiveness to immune checkpoint therapy by enhancing CD8+ T cell antitumor immunity
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    biorxiv.org/content/10.64898/2026.04.15.718788v1
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    Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis
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    sciencedirect.com/science/article/pii/S0304383526002545
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    Upregulation of TNFR2 Precedes TOX Expression by Exhausted T cells and Restricts Antitumor and Antiviral Immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056295/
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    Hierarchical Targeting of TREM2+ Myeloid Cells via Acid-Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone-Metastatic TNBC
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202517369
  18. Mar 2026
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A phase II study of docetaxel and pembrolizumab plus Interleukin-12 gene therapy in non-metastatic, anthracycline-refractory triple negative breast cancer (INTEGRAL)
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    Microglia Display Heterogeneous Initial Responses to Disseminated Tumor Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012254/
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    6-Hydroxydopamine promotes antitumor immunity through macrophage remodeling beyond sympathetic ablation
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    sciencedirect.com/science/article/pii/S0896627326001339
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    Detachment-Induced FAK-STAT3-NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202522837
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    In vivo Auto-tuning of Antibody-Drug Conjugate Delivery to Maximize Efficacy using High-Avidity, Low-Affinity Antibodies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12964248/
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    Large adipocytes increase vesicle-mediated lipid release and promote breast cancer malignancy
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    Inhibition of MCL-1 and MEK overcomes MEK inhibitor resistance in triple-negative and inflammatory breast cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12354021/
  26. Feb 2026
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An AIB1 isoform rewires glucocorticoid receptor signaling to promote TNBC progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12907120/
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    Weight Loss Reverses the Effects of Aging and Obesity on Mammary Tumor Immunosuppression and Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316554/
  29. Jan 2026
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair
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    pmc.ncbi.nlm.nih.gov/articles/PMC12806335/
  31. Dec 2025
  32. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Aberrant hypothalamic neuronal activity blunts glucocorticoid diurnal rhythms in murine breast cancer
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  33. Nov 2025
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    Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells
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    sciencedirect.com/science/article/pii/S2666379125005191
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    Non-orthosteric inhibition of enolase 1 impedes growth of triple-negative breast cancer
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    Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis
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    Atractylodes macrocephala Koidz. Polysaccharide Alleviates Chemotherapy-Induced Depression-Like Behaviors Through the Gut–Brain Axis
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    Co-targeting CDK4/6 enhances anti-cancer activity and alleviates immune-related adverse events of anti-PD-1 antibody for breast cancer
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  39. Oct 2025
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    Large adipocytes alter mode of lipid release and promote breast cancer malignancy
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  41. Sep 2025
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    TSH Ligand-Based CAR-T Cell Effectively Eradicates TSHR-Positive Thyroid Cancer with Favorable Safety Profile
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202513243
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    Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression
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    Drug screening in 3D microtumors reveals DDR1/2-MAPK12-GLI1 as a vulnerability in cancer-associated fibroblasts
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    Modulation of fibronectin extracellular matrix enhances anti-tumor efficacy of immune checkpoint blockade
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    Peach Gum Polysaccharide Prevents Chemotherapy-Induced Intestinal Injury and Degenerative Behavior
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    pmc.ncbi.nlm.nih.gov/articles/PMC12375157/
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    Tumors hijack macrophages for iron supply to promote bone metastasis and anemia
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  48. Aug 2025
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    Peach Gum Polysaccharide Prevents Chemotherapy-Induced Intestinal Injury and Degenerative Behavior
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    Fc-optimized CD40 agonistic antibody elicits tertiary lymphoid structure formation and systemic antitumor immunity in metastatic cancer
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    sciencedirect.com/science/article/pii/S1535610825003198
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    T cells Instruct Immune Checkpoint Inhibitor Therapy Resistance in Tumors Responsive to IL-1 and TNFα Inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790381/
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    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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    Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases
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  54. Jul 2025
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    Secretogranin 2 binds LILRB4 resulting in immunosuppression
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    nature.com/articles/s41590-025-02233-4
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MARCO expression on myeloid-derived suppressor cells is essential for their differentiation and immunosuppression
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    A fluorescent STING ligand sensor for high-throughput screening of compounds that can enhance tumor immunotherapy
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    Genetic and pharmacological targeting of nicotinic acetylcholine receptor action blocks tumor progression in mouse models of breast cancer
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    dx.doi.org/10.1093/jimmun/vkaf148
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
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    The immune response against cancer is modulated by stromal cell fibronectin
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  61. Jun 2025
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  63. May 2025
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    EYA3 regulation of NF-κB and CCL2 suppresses cytotoxic NK cells in the premetastatic niche to promote TNBC metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12057687/
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    Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer
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    sciencedirect.com/science/article/pii/S2211124725004474
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    Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1074761325001839
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    Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35471
  68. Apr 2025
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    cGAS and STING in Host Myeloid Cells Are Essential for Effective Cyclophosphamide Treatment of Advanced Breast Cancer
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    Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion
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  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fluorescence Lifetime Imaging Enables In Vivo Quantification of PD-L1 Expression and Intertumoral Heterogeneity
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  74. Mar 2025
  75. www.biorxiv.org www.biorxiv.org
    TEAD inhibition alters the lung immune microenvironment and attenuates metastasis
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    biorxiv.org/content/10.1101/2025.02.26.639326v1
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    Blocking WNT7A Enhances MHC-I Antigen Presentation and Enhances the Effectiveness of Immune Checkpoint Blockade Therapy
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    aacrjournals.org/cancerimmunolres/article/13/3/400/752015/Blocking-WNT7A-Enhances-MHC-I-Antigen-Presentation
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    DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity
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  78. Feb 2025
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    Triple-negative breast cancer-derived extracellular vesicles promote a hepatic pre-metastatic niche via a cascade of microenvironment remodeling
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    aacrjournals.org/mcr/article/21/7/726/727474/Triple-Negative-Breast-Cancer-Derived
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    Single-cell Transcriptomic Analysis Identifies Senescent Osteocytes that Trigger Bone Destruction in Breast Cancer Metastasis
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    aacrjournals.org/cancerres/article/84/23/3936/750181/Single-Cell-Transcriptomic-Analysis-Identifies
  83. Jan 2025
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    The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis
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  86. Dec 2024
  87. www.sciencedirect.com www.sciencedirect.com
    Antigen presentation by tumor-associated macrophages drives T cells from a progenitor exhaustion state to terminal exhaustion
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    Arming Oncolytic M1 Virus with Gasdermin E Enhances Antitumor Efficacy in Breast Cancer
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    sciencedirect.com/science/article/pii/S2589004224023733
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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  90. Nov 2024
  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis
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  93. Sep 2024
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11401886/
  95. Jul 2024
  96. www.sciencedirect.com www.sciencedirect.com
    Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
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  97. May 2024
  98. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    sciencedirect.com/science/article/pii/S1535610824001697
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    Preclinical and translational pharmacology of afucosylated anti-CCR8 antibody for depletion of tumour-infiltrating regulatory T cells
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16326
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    Identification of the extracellular membrane protein ENPP3 as a major cGAMP hydrolase and innate immune checkpoint
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    sciencedirect.com/science/article/pii/S2211124724005370
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    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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  102. www.biorxiv.org www.biorxiv.org
    Direct excitatory synapses between neurons and tumor cells drive brain metastatic seeding of breast cancer and melanoma
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    biorxiv.org/content/10.1101/2024.01.08.574608v1
  103. Apr 2024
  104. aacrjournals.org aacrjournals.org
    Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
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    aacrjournals.org/cancerdiscovery/article/13/12/2610/731625/Spatial-and-Temporal-Mapping-of-Breast-Cancer-Lung
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10980159/
  106. Mar 2024
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    Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming
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    sciencedirect.com/science/article/pii/S0304383524002179
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    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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  109. Feb 2024
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
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  111. Jan 2024
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  117. Nov 2023
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  121. Jul 2023
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  123. Jun 2023
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  125. May 2023
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  131. Apr 2023
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  134. Mar 2023
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  137. Feb 2023
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  139. Jan 2023
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  141. www.science.org www.science.org
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  145. Dec 2022
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  147. Nov 2022
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  150. Sep 2022
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  152. Jun 2022
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  155. Apr 2022
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  157. Mar 2022
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  159. Dec 2021
  160. mcr.aacrjournals.org mcr.aacrjournals.org
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  161. Nov 2021
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  164. Sep 2021
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  166. Aug 2021
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  168. Jun 2021
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  170. May 2021
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  173. Apr 2021
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  175. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  176. Feb 2021
  177. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  178. Jan 2021
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  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  181. Dec 2020
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  183. Nov 2020
  184. www.frontiersin.org www.frontiersin.org
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  185. Sep 2020
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  187. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  190. Jan 2020
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    Contrasting Effects of IGF Binding Protein-3 Expression in Mammary Tumor Cells and the Tumor Microenvironment
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  192. Nov 2017
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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