Hypothesis

17 Matching Annotations

Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microglia in diffuse midline glioma contribute to extracellular matrix remodelling and cancer cell invasion

1
1. scibot 03 Jun 2026
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1038/s41419-026-08891-y
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
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  RRID:CVCL_IT41
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pmc.ncbi.nlm.nih.gov/articles/PMC13222350/
Mar 2024
www.sciencedirect.com www.sciencedirect.com

MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors

2
1. scibot 07 Mar 2024
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1016/j.isci.2024.109188
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41
2. scibot 06 Mar 2024
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1016/j.isci.2024.109188
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41
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scibot

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sciencedirect.com/science/article/pii/S2589004224004097
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence

1
1. scibot 05 Jan 2024
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1158/1535-7163.MCT-23-0026
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41
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ncbi.nlm.nih.gov/pmc/articles/PMC10762335/
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

2
1. scibot 03 Nov 2023
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1158/2159-8290.CD-23-0131
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41
2. scibot 03 Nov 2023
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1158/2159-8290.CD-23-0131
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10618742/
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas

1
1. scibot 09 May 2023
  
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  RRID:CVCL_IT41
  
  DOI: 10.1073/pnas.2221175120
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_IT41
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10161095/
Dec 2022
aacrjournals.org aacrjournals.org

BAF complex maintains glioma stem cells in pediatric H3K27M-glioma

1
1. scibot 03 Dec 2022
  
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  RRID:CVCL_IT41
  
  DOI: 10.1158/2159-8290.CD-21-1491
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
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aacrjournals.org/cancerdiscovery/article/12/12/2880/711164/BAF-Complex-Maintains-Glioma-Stem-Cells-in
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits

1
1. scibot 02 Nov 2022
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1158/0008-5472.CAN-22-0671
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41
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ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

1
1. scibot 18 Jun 2022
  
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  RRID:CVCL_IT41
  
  DOI: 10.1016/j.molcel.2022.05.023
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41
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sciencedirect.com/science/article/pii/S1097276522004907
May 2022
www.sciencedirect.com www.sciencedirect.com

H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape

1
1. scibot 19 May 2022
  
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  RRID:CVCL_IT41
  
  DOI: 10.1016/j.celrep.2022.110836
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41
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sciencedirect.com/science/article/pii/S221112472200609X
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Splicing is an alternate oncogenic pathway activation mechanism in glioma

2
1. scibot 11 Feb 2022
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1038/s41467-022-28253-4
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41
2. scibot 10 Feb 2022
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1038/s41467-022-28253-4
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41
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ncbi.nlm.nih.gov/pmc/articles/PMC8803922/
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of microglial EZH2 leads to anti-tumoral effects in pediatric diffuse midline gliomas

1
1. scibot 04 Sep 2021
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1093/noajnl/vdab096
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41
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ncbi.nlm.nih.gov/pmc/articles/PMC8409254/
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1016/j.ccell.2019.09.005
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41 RRIDCUR:Validated
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RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819304258
Jul 2021
www.sciencedirect.com www.sciencedirect.com

N6-methyladenine DNA Modification in Glioblastoma

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1016/j.cell.2018.10.006
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRIDCUR:Validated RRID:CVCL_IT41
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scibot

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sciencedirect.com/science/article/pii/S009286741831314X
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas

1
1. scibot 20 Apr 2021
  
  in Public
  
  RRID:CVCL_IT41
  
  DOI: 10.1016/j.ccell.2020.07.008
  
  Resource: (RRID:CVCL_IT41)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_IT41
  
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  RRID:CVCL_IT41 RRIDCUR:Validated
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RRID:CVCL_IT41

RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S153561082030369X