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    Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.78132
  3. Sep 2026
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astrocytic <fc>PDE7B</fc> Drives Blood–Brain Barrier Breakdown via Extracellular Vesicles in Demyelinating Disease
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    onlinelibrary.wiley.com/doi/10.1002/glia.70223
  5. Aug 2026
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    Engineered mechanosensitive MSCs enable synthetic radiotheranostic targeting across tumor types
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    sciencedirect.com/science/article/pii/S1934590926002754
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70556
  8. Jul 2026
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    Dl-3-n-Butylphthalide Protects Human Brain Microvascular Endothelial Cells Against Ischemic Injury Through Dual Modulation of HIF1α/VEGF-Mediated Angiogenesis and COX2-Mediated Inflammation
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    imrpress.com/journal/JIN/25/7/10.31083/JIN51032
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    Human iPSC-derived engineered heart tissue model of diastolic dysfunction in heart failure with preserved ejection fraction
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    sciencedirect.com/science/article/pii/S1934590926002341
  11. Jun 2026
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    Refined single-cell profiling captures a CCR5high CD4+ cytotoxic T-cell precursor in multiple sclerosis
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  13. Apr 2026
  14. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Tuneable Permeability of Cellulose Nanofibrils-based Membranes in Next-Generation Barrier-On-Chip Systems
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    chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.202500843
  15. Mar 2026
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    A Physiological Microfluidic Blood–Brain-Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202600019
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    Decoding the spatiotemporal development of the blood-brain barrier in human cortex
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    sciencedirect.com/science/article/pii/S1934590926000809
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    Nature-Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202518969
  19. Feb 2026
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    Targeting α7nAChR-driven brain endothelial pyroptosis mitigates HIV-1 gp120-induced blood–brain barrier breakdown
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    sciencedirect.com/science/article/pii/S0889159126002266
  21. Nov 2025
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    The effects of doxorubicin on blood-brain barrier integrity in hCMEC/D3
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    sciencedirect.com/science/article/pii/S0161813X25001615
  23. Oct 2025
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    Inhibition of constitutive activity of the atypical chemokine receptor ACKR3 by the small-molecule inverse agonist VUF16840
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    sciencedirect.com/science/article/pii/S0026895X25157453
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neurogranin-MYH9 interaction regulates cytoskeletal remodeling in cerebral vasculature
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    pmc.ncbi.nlm.nih.gov/articles/PMC12487352/
  26. Aug 2025
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    Histamine 1 receptors and reverse-mode Na+/Ca2+ exchanger drive extracellular Na+-dependent intracellular Ca2+ oscillations in human cerebrovascular endothelial cells
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    sciencedirect.com/science/article/pii/S0143416025000764
  28. Jul 2025
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    Acquisition of residency programs by T cells entering the human brain
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    sciencedirect.com/science/article/pii/S2211124725007314
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted and Untargeted Proteomics-based Comparison of Adenoviral Infected hCMEC/D3 and hBMEC as a Human Brain Endothelial Cells to Study the OATP2B1 Transporter
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  31. May 2025
  32. 52.53.155.43 52.53.155.43
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    A heterodimer of hemoglobin identifies theranostic targets on brain-metastasizing melanoma cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35458
  34. Feb 2025
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    Vasorin exocytosed from glioma cells facilitates angiogenesis via VEGFR2/AKT signaling pathway
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    aacrjournals.org/mcr/article/22/7/668/746072/Vasorin-Exocytosed-from-Glioma-Cells-Facilitates
  36. Dec 2024
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    Targeted Proteomics for Absolute Quantification of Glucose Transporter 1 in Mammalian Brain Cells Using Liquid Chromatography-Mass Spectrometry
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  38. Nov 2024
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neurons enhance blood–brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion
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    pmc.ncbi.nlm.nih.gov/articles/PMC11524583/
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    Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier
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  41. Aug 2024
  42. www.physiology.org www.physiology.org
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    physiology.org/doi/abs/10.1152/ajpcell.00116.2017
  43. Jul 2024
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    Hexokinase 1 forms rings that regulate mitochondrial fission during energy stress
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    sciencedirect.com/science/article/pii/S1097276524005124
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    IDO1 Inhibitor RY103 Suppresses Trp-GCN2-Mediated Angiogenesis and Counters Immunosuppression in Glioblastoma
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  46. May 2024
  47. 52.53.155.43 52.53.155.43
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    A face-to-face comparison of the BBB cell models hCMEC/D3 and hBMEC for their applicability to adenoviral expression of transporters
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16125
  49. Apr 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11001299/
  51. Mar 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammation-induced TRPV4 channels exacerbate blood–brain barrier dysfunction in multiple sclerosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10960997/
  53. Feb 2024
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increased Expression of Transferrin Receptor 1 in the Brain Cortex of 5xFAD Mouse Model of Alzheimer’s Disease Is Associated with Activation of HIF-1 Signaling Pathway
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  55. Sep 2023
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    Sox17 protects human brain microvascular endothelial cells from AngII-induced injury by regulating autophagy and apoptosis
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    link.springer.com/article/10.1007/s11010-023-04838-5
  57. Mar 2023
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    Functional and targeted proteomics characterization of a human primary endothelial cell model of the blood-brain barrier (BBB) for drug permeability studies
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  59. Jan 2023
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism
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    ncbi.nlm.nih.gov/pmc/articles/PMC9851883/
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    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    ovid.com/jnls/nrronline/fulltext/10.4103/1673-5374.327335~guardians-of-the-eye-new-tales-about-retinal-microglia-and
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  63. www.ovid.com www.ovid.com
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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  64. Oct 2022
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    Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis
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    sciencedirect.com/science/article/pii/S2666634022004081
  66. Aug 2022
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-Estradiol 17-acetate enhances the in vitro vitality of endothelial cells isolated from the brain of patients subjected to neurosurgery
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    ncbi.nlm.nih.gov/pmc/articles/PMC9396507/
  68. Apr 2022
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Copper bis(thiosemicarbazone) complexes modulate P-glycoprotein expression and function in human brain microvascular endothelial cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15609
  70. Nov 2021
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8553622/
  72. Aug 2021
  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  75. Jul 2021
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    Implication of long non-coding RNA NEAT1 in the pathogenesis of bacterial meningitis-induced blood-brain barrier damage
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    sciencedirect.com/science/article/pii/S0026286221000959
  77. May 2021
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    SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt
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  79. Feb 2021
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    The role of LR-TIMAP/PP1c complex in the occurrence and development of no-reflow
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    Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model
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    onlinelibrary.wiley.com/doi/full/10.1111/jne.12931
  82. Nov 2020
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    Impact of Wnt/β‐catenin signaling on ethanol‐induced changes in brain endothelial cell permeability
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  84. Sep 2020
  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Receptor for Advanced Glycation End Products Upregulation in Cerebral Endothelial Cells Mediates Cerebrovascular‐related Amyloid β Accumulation after Porphyromonas gingivalis Infection
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    Involvement of a Na + -coupled Oligopeptide Transport System for β-amyloid Peptide (Aβ 1–42 ) in Brain Cells
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    link.springer.com/article/10.1007/s11095-020-02835-7
  87. Jan 2020
  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Amyloid beta25‐35 impairs docosahexaenoic acid efflux by down‐regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells
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    onlinelibrary.wiley.com/doi/abs/10.1111/jnc.14722
  89. link.springer.com link.springer.com
    Oxygen-Glucose Deprivation/Reoxygenation-Induced Barrier Disruption at the Human Blood–Brain Barrier is Partially Mediated Through the HIF-1 Pathway
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    link.springer.com/article/10.1007/s12017-019-08531-z
  90. Nov 2018
  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Dietary Docosahexaenoic Acid Supplementation Enhances Expression of Fatty Acid‐Binding Protein 5 at the Blood‐Brain Barrier and Brain Docosahexaenoic Acid Levels
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  93. www.physiology.org www.physiology.org
    Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells | American Journal of Physiology-Cell Physiology
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    physiology.org/doi/full/10.1152/ajpcell.00116.2017
  94. Nov 2017
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5057206/
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    Isogenic blood–brain barrier models based on patient‐derived stem cells display inter‐individual differences in cell maturation and functionality
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14040/full
  97. Nov 2016
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells
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