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    Targeting α7nAChR-driven brain endothelial pyroptosis mitigates HIV-1 gp120-induced blood–brain barrier breakdown
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    sciencedirect.com/science/article/pii/S0889159126002266
  3. Nov 2025
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    The effects of doxorubicin on blood-brain barrier integrity in hCMEC/D3
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    sciencedirect.com/science/article/pii/S0161813X25001615
  5. Oct 2025
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    Inhibition of constitutive activity of the atypical chemokine receptor ACKR3 by the small-molecule inverse agonist VUF16840
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    sciencedirect.com/science/article/pii/S0026895X25157453
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    Neurogranin-MYH9 interaction regulates cytoskeletal remodeling in cerebral vasculature
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    pmc.ncbi.nlm.nih.gov/articles/PMC12487352/
  8. Aug 2025
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    Histamine 1 receptors and reverse-mode Na+/Ca2+ exchanger drive extracellular Na+-dependent intracellular Ca2+ oscillations in human cerebrovascular endothelial cells
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    sciencedirect.com/science/article/pii/S0143416025000764
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    Acquisition of residency programs by T cells entering the human brain
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    Targeted and Untargeted Proteomics-based Comparison of Adenoviral Infected hCMEC/D3 and hBMEC as a Human Brain Endothelial Cells to Study the OATP2B1 Transporter
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    A heterodimer of hemoglobin identifies theranostic targets on brain-metastasizing melanoma cells
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  16. Feb 2025
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    Vasorin exocytosed from glioma cells facilitates angiogenesis via VEGFR2/AKT signaling pathway
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  18. Dec 2024
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    Targeted Proteomics for Absolute Quantification of Glucose Transporter 1 in Mammalian Brain Cells Using Liquid Chromatography-Mass Spectrometry
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  20. Nov 2024
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    Neurons enhance blood–brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion
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    Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier
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  23. Aug 2024
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  25. Jul 2024
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    Hexokinase 1 forms rings that regulate mitochondrial fission during energy stress
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    IDO1 Inhibitor RY103 Suppresses Trp-GCN2-Mediated Angiogenesis and Counters Immunosuppression in Glioblastoma
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  28. May 2024
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    A face-to-face comparison of the BBB cell models hCMEC/D3 and hBMEC for their applicability to adenoviral expression of transporters
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16125
  31. Apr 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1
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  33. Mar 2024
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    Inflammation-induced TRPV4 channels exacerbate blood–brain barrier dysfunction in multiple sclerosis
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  35. Feb 2024
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increased Expression of Transferrin Receptor 1 in the Brain Cortex of 5xFAD Mouse Model of Alzheimer’s Disease Is Associated with Activation of HIF-1 Signaling Pathway
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  37. Sep 2023
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    Sox17 protects human brain microvascular endothelial cells from AngII-induced injury by regulating autophagy and apoptosis
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  39. Mar 2023
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    Functional and targeted proteomics characterization of a human primary endothelial cell model of the blood-brain barrier (BBB) for drug permeability studies
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  41. Jan 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism
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    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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  44. Dec 2022
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    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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  46. Oct 2022
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    Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis
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    sciencedirect.com/science/article/pii/S2666634022004081
  48. Aug 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-Estradiol 17-acetate enhances the in vitro vitality of endothelial cells isolated from the brain of patients subjected to neurosurgery
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  50. Apr 2022
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Copper bis(thiosemicarbazone) complexes modulate P-glycoprotein expression and function in human brain microvascular endothelial cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15609
  52. Nov 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8553622/
  54. Aug 2021
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  57. Jul 2021
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    Implication of long non-coding RNA NEAT1 in the pathogenesis of bacterial meningitis-induced blood-brain barrier damage
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    sciencedirect.com/science/article/pii/S0026286221000959
  59. May 2021
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    SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt
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  61. Feb 2021
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    The role of LR-TIMAP/PP1c complex in the occurrence and development of no-reflow
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    Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model
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    onlinelibrary.wiley.com/doi/full/10.1111/jne.12931
  64. Nov 2020
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    Impact of Wnt/β‐catenin signaling on ethanol‐induced changes in brain endothelial cell permeability
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  66. Sep 2020
  67. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Receptor for Advanced Glycation End Products Upregulation in Cerebral Endothelial Cells Mediates Cerebrovascular‐related Amyloid β Accumulation after Porphyromonas gingivalis Infection
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    Involvement of a Na + -coupled Oligopeptide Transport System for β-amyloid Peptide (Aβ 1–42 ) in Brain Cells
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    link.springer.com/article/10.1007/s11095-020-02835-7
  69. Jan 2020
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Amyloid beta25‐35 impairs docosahexaenoic acid efflux by down‐regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells
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    onlinelibrary.wiley.com/doi/abs/10.1111/jnc.14722
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    Oxygen-Glucose Deprivation/Reoxygenation-Induced Barrier Disruption at the Human Blood–Brain Barrier is Partially Mediated Through the HIF-1 Pathway
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    link.springer.com/article/10.1007/s12017-019-08531-z
  72. Nov 2018
  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Dietary Docosahexaenoic Acid Supplementation Enhances Expression of Fatty Acid‐Binding Protein 5 at the Blood‐Brain Barrier and Brain Docosahexaenoic Acid Levels
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  75. www.physiology.org www.physiology.org
    Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells | American Journal of Physiology-Cell Physiology
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    physiology.org/doi/full/10.1152/ajpcell.00116.2017
  76. Nov 2017
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5057206/
  78. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Isogenic blood–brain barrier models based on patient‐derived stem cells display inter‐individual differences in cell maturation and functionality
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14040/full
  79. Nov 2016
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells
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