Hypothesis

26 Matching Annotations

Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CAR binders affect CAR T-cell tonic signaling, durability, and sensitivity to target

1
1. scibot 05 Dec 2025
  
  in Public
  
  RRID:CVCL_UJ05
  
  DOI: 10.1158/2326-6066.CIR-24-1347
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_UJ05
  
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  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12137003/
Aug 2025
52.53.155.43 52.53.155.43

1-s2.0-S152500162500632X-main-html.html

1
1. scibot 07 Aug 2025
  
  in Public
  
  RRID:CVCL_UJ05
  
  DOI: 10.1016/j.ymthe.2025.08.002
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_UJ05
  
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  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

52.53.155.43/f1b425f385342138f215a5cad3fcee94c921b213/1-s2.0-S152500162500632X-main-html.html
Jun 2025
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 11 Jun 2025
  
  in Public
  
  RRID:CVCL_UJ05
  
  DOI: 10.1111/bph.70089
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_UJ05
  
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  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70089
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity

1
1. scibot 15 Apr 2025
  
  in Public
  
  RRID:CVCL_UJ05
  
  DOI: 10.1016/j.cell.2025.03.017
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_UJ05
  
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  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425002909
www.sciencedirect.com www.sciencedirect.com

Library-based single-cell analysis of CAR signaling reveals drivers of in vivo persistence

1
1. scibot 11 Apr 2025
  
  in Public
  
  RRID: CVCL_UJ05
  
  DOI: 10.1016/j.cels.2025.101260
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_UJ05
  
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  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S2405471225000936
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Design of sensitive monospecific and bispecific synthetic chimeric T cell receptors for cancer therapy

1
1. scibot 26 Mar 2025
  
  in Public
  
  CRL-3273
  
  DOI: 10.1038/s43018-025-00927-0
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:CVCL_UJ05
  
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  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12037409/
www.sciencedirect.com www.sciencedirect.com

Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia

1
1. scibot 11 Mar 2025
  
  in Public
  
  RRID:CVCL_UJ05
  
  DOI: 10.1016/j.ccell.2025.02.008
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_UJ05
  
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  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825000601
www.cell.com www.cell.com

Metabolic engineering to facilitate anti-tumor immunity

1
1. scibot 07 Mar 2025
  
  in Public
  
  CRL-3273
  
  DOI: 10.1016/j.ccell.2025.02.004
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:CVCL_UJ05
  
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  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

cell.com/cancer-cell/abstract/S1535-6108(25)00056-X
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor

1
1. scibot 30 Jan 2025
  
  in Public
  
  ATCCCat#CRL-3273
  
  DOI: 10.1016/j.medj.2024.09.010
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S2666634024003775
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Smarcd1 subunit of SWI/SNF chromatin-remodeling complexes collaborates with E2a to promote murine lymphoid specification

1
1. scibot 04 Sep 2024
  
  in Public
  
  Cat# CRL-3273
  
  DOI: 10.1016/j.devcel.2024.08.007
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_UJ05
  
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  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S1534580724004908
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-cell systems pharmacology identifies development-driven drug response and combination therapy in B cell acute lymphoblastic leukemia

1
1. scibot 09 Apr 2024
  
  in Public
  
  CRL-3273
  
  DOI: 10.1016/j.ccell.2024.03.003
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11008188/
www.sciencedirect.com www.sciencedirect.com

Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway

1
1. scibot 05 Apr 2024
  
  in Public
  
  CRL-3273
  
  DOI: 10.1016/j.celrep.2024.114065
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724003930
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Inhibition of CD38 enzymatic activity enhances CAR-T cell immune-therapeutic efficacy by repressing glycolytic metabolism

1
1. scibot 02 Feb 2024
  
  in Public
  
  Nalm6 cell lineATCCCat#CRL-3273
  
  DOI: 10.1016/j.xcrm.2024.101400
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S2666379124000090
May 2023
52.53.155.43 52.53.155.43

Intrinsic tumor resistance to CAR T cells is a dynamic transcriptional state that is exploitable with low-dose radiation

1
1. scibot 19 May 2023
  
  in Public
  
  RRID:CVCL_UJ05
  
  DOI: 10.1182/bloodadvances.2022009543
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_UJ05
  
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  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

52.53.155.43/c3edf1bcbe114757202a2e57dfb535e151ecf522/RRID8-html.html
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950

1
1. scibot 20 Apr 2023
  
  in Public
  
  RRID:CVCL_UJ05
  
  DOI: 10.1158/2767-9764.CRC-22-0310
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
Jan 2023
www.sciencedirect.com www.sciencedirect.com

CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance

1
1. scibot 26 Jan 2023
  
  in Public
  
  Cat# CRL-3273
  
  DOI: 10.1016/j.xcrm.2023.100917
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @MufeiL
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S2666379123000022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inducing T cell dysfunction by chronic stimulation of CAR-engineered T cells targeting cancer cells in suspension cultures

1
1. scibot 11 Jan 2023
  
  in Public
  
  Nalm6, clone G5
  
  DOI: 10.1016/j.xpro.2022.101954
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9826863/
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Expression of inducible factors reprograms CAR-T cells for enhanced function and safety

1
1. scibot 13 Dec 2022
  
  in Public
  
  CRL-3273
  
  DOI: 10.1016/j.ccell.2022.11.006
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S1535610822005530
Oct 2022
www.sciencedirect.com www.sciencedirect.com

Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy

1
1. scibot 20 Oct 2022
  
  in Public
  
  CRL-3273
  
  DOI: 10.1016/j.immuni.2022.09.014
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S1074761322005088
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Efficient generation of locus-specific human CAR-T cells with CRISPR/cCas12a

1
1. scibot 15 Apr 2022
  
  in Public
  
  ATCCCRL-3273
  
  DOI: 10.1016/j.xpro.2022.101321
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S2666166722002015
Mar 2022
www.sciencedirect.com www.sciencedirect.com

A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy

1
1. scibot 18 Mar 2022
  
  in Public
  
  ATCCCatalog Number:3273
  
  DOI: 10.1016/j.cmet.2022.02.009
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S1550413122000535
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses

1
1. scibot 19 Nov 2021
  
  in Public
  
  RRID:CVCL_UJ05
  
  DOI: 10.1038/s41467-021-26771-1
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05
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RRID:CVCL_UJ05

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8586369/
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Targeting folate receptor beta on monocytes/macrophages renders rapid inflammation resolution independent of root causes

1
1. scibot 20 Oct 2021
  
  in Public
  
  CRL-3273
  
  DOI: 10.1016/j.xcrm.2021.100422
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_UJ05
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RRIDCUR:Missing

RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S2666379121002846
www.sciencedirect.com www.sciencedirect.com

Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates

1
1. scibot 14 Oct 2021
  
  in Public
  
  CRL-3273
  
  DOI: 10.1016/j.molcel.2021.09.021
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_UJ05

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scibot

URL

sciencedirect.com/science/article/pii/S1097276521007735
Aug 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_UJ05
  
  DOI: 10.1111/bph.14809
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRID:CVCL_UJ05 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_UJ05

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scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14809
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

1
1. scibot 24 Apr 2021
  
  in Public
  
  CRL-3273
  
  DOI: 10.1016/j.cell.2020.07.009
  
  Resource: (ATCC Cat# CRL-3273, RRID:CVCL_UJ05)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_UJ05
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_UJ05
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RRIDCUR:Missing

RRID:CVCL_UJ05

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867420308746