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  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
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    1. scibot 17 Jul 2024
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    sciencedirect.com/science/article/pii/S2211124724007460
  3. Jul 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1
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    1. scibot 12 Jul 2024
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    sciencedirect.com/science/article/pii/S1097276524005239
  5. Jun 2024
  6. www.nature.com www.nature.com
    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
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    1. scibot 28 Jun 2024
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      DOI: 10.1038/s41594-024-01338-y

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    nature.com/articles/s41594-024-01338-y
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    Electro-elution-based purification of covalent DNA–protein cross-links
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    1. scibot 28 Jun 2024
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      DOI: 10.1038/s41596-024-01004-z

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    link.springer.com/article/10.1038/s41596-024-01004-z
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    Integrating genome-wide CRISPR screens and in silico drug profiling for targeted antidote development
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    1. scibot 06 Jun 2024
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    nature.com/articles/s41596-024-00995-z
  9. May 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry
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    1. scibot 22 May 2024
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      DOI: 10.1007/s00401-024-02729-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11102361/
  11. Apr 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for RNA-binding protein TIA1 for use in Western Blot, immunoprecipitation and immunofluorescence
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    1. scibot 20 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11024596/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type I interferon regulation by USP18 is a key vulnerability in cancer
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    1. scibot 20 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11022047/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early recovery of proteasome activity in cells pulse-treated with proteasome inhibitors is independent of DDI2
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    1. scibot 18 Apr 2024
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      DOI: 10.7554/eLife.91678

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    ncbi.nlm.nih.gov/pmc/articles/PMC11018354/
  15. www.biorxiv.org www.biorxiv.org
    Fragility of ER homeostatic regulation underlies haploid instability in human somatic cells
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    1. scibot 12 Apr 2024
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      DOI: 10.1101/2024.04.05.588249

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    biorxiv.org/content/10.1101/2024.04.05.588249v1
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence
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    1. scibot 03 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10979127/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator
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    1. scibot 03 Apr 2024
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      DOI: 10.1021/acs.jmedchem.3c02245

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983002/
  18. Mar 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence
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    1. scibot 06 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905012/
  20. Feb 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
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    1. scibot 21 Feb 2024
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    sciencedirect.com/science/article/pii/S1097276524000893
  22. www.biorxiv.org www.biorxiv.org
    qTAG: An adaptable CRISPR-based endogenous tagging protocol using optimized repair cassettes.
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    1. scibot 04 Feb 2024
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      DOI: 10.1101/2023.11.01.565029

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    biorxiv.org/content/10.1101/2023.11.01.565029v2
  23. dx.doi.org dx.doi.org
    Functional assay for assessment of pathogenicity of BAP1 variants
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    1. scibot 03 Feb 2024
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      DOI: 10.1093/hmg/ddad193

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    dx.doi.org/10.1093/hmg/ddad193
  24. Jan 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for Apolipoprotein E for use in Western Blot and immunoprecipitation
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    1. scibot 05 Jan 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10755264/
  26. Dec 2023
  27. www.nature.com www.nature.com
    Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype
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    1. scibot 02 Dec 2023
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      DOI: 10.1038/s41467-023-43657-6

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    nature.com/articles/s41467-023-43657-6
  28. Nov 2023
  29. www.sciencedirect.com www.sciencedirect.com
    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
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    1. scibot 28 Nov 2023
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    sciencedirect.com/science/article/pii/S1097276523008493
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12
    1
    1. scibot 15 Nov 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10639087/
  31. Oct 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity
    1
    1. scibot 31 Oct 2023
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      DOI: 10.1038/s41467-023-42342-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10611716/
  33. www.sciencedirect.com www.sciencedirect.com
    Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method
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    1. scibot 28 Oct 2023
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    sciencedirect.com/science/article/pii/S1534580723004951
  34. Sep 2023
  35. www.biorxiv.org www.biorxiv.org
    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
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    1. scibot 30 Sep 2023
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      DOI: 10.1101/2023.09.25.559255

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    biorxiv.org/content/10.1101/2023.09.25.559255v1
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Coiled-coil-helix-coiled-coil-helix domain containing protein 10 (CHCHD10) for use in Western Blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 29 Sep 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10521100/
  37. Aug 2023
  38. www.science.org www.science.org
    Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12
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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Profilin-1 for use in Western blot, immunoprecipitation and immunofluorescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC10415725/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence
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    1. scibot 10 Aug 2023
      CVCL_Y019

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    ncbi.nlm.nih.gov/pmc/articles/PMC10403746/
  41. Jul 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
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    sciencedirect.com/science/article/pii/S2211124723008185
  43. Jun 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-preforming antibodies for Ubiquilin-2 for use in Western Blot, immunoprecipitation, and immunofluorescence
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    1. scibot 27 Jun 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285353/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for TDP-43 for use in Western Blot, immunoprecipitation and immunofluorescence
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    1. scibot 24 Jun 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285334/
  46. 52.53.155.43 52.53.155.43
    The identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence
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    1. scibot 23 Jun 2023
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    2. scibot 15 Jun 2023
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    52.53.155.43/3699d5f980e0b6171344a18f720674e249948766/7d387731-c0ad-4a85-8ff4-5af49adcc5bc_133696_-_kathleen_southern-html.html
  47. 52.53.155.43 52.53.155.43
    The identification of high-performing antibodies for Coiled-coil-helix-coiled-coil-helix domain containing protein 10 (CHCHD10) for use in Western Blot, immunoprecipitation and immunofluorescence
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    1. scibot 15 Jun 2023
      CVCL_Y019

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    52.53.155.43/7ca82bf96d7646b3c99e77a42b1df42af8410c8b/05cb805d-1af6-47d7-a0e5-2c25cb48aca8_133479_-_kathleen_southern-html.html
  48. 52.53.155.43 52.53.155.43
    The identification of high-performing antibodies for Midkine for use in Western blot and immunoprecipitation
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    52.53.155.43/5a59890f8b795ae07e053fb5e51e3758d1bced38/988b674f-b8fd-4046-8eb4-41f742fe2791_130587_-_kathleen_southern-html.html
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APOE expression and secretion are modulated by mitochondrial dysfunction
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    ncbi.nlm.nih.gov/pmc/articles/PMC10231934/
  50. May 2023
  51. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/55175f335d9d63eca4c96b1d663be208d4b843b1/Molecular Oncology - 2023 - Koob - MND1 enables homologous recombination in somatic cells primarily outside the context of-html.html
  52. www.sciencedirect.com www.sciencedirect.com
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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    1. scibot 10 May 2023
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    sciencedirect.com/science/article/pii/S2211124723004953
  53. Apr 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Salmonella invasion of a cell is self-limiting due to effector-driven activation of N-WASP
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      DOI: 10.1016/j.isci.2023.106643

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    sciencedirect.com/science/article/pii/S2589004223007204
  55. Mar 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1
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    sciencedirect.com/science/article/pii/S2211124723003327
  57. Feb 2023
  58. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13379
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chikungunya virus entry and infectivity is primarily facilitated through cell line dependent attachment factors in mammalian and mosquito cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9895848/
  60. Jan 2023
  61. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    ANALYSIS OF A PANEL OF TMEM16A CHLORIDE CHANNEL INHIBITORS REVEALS INDIRECT MECHANISMS INVOLVING ALTERATION OF CALCIUM SIGNALING
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  62. www.sciencedirect.com www.sciencedirect.com
    Rabies virus P protein binds to TBK1 and interferes with the formation of innate immunity-related liquid condensates
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    sciencedirect.com/science/article/pii/S2211124722018502
  63. Nov 2022
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Mitochondrial RNA Granule Modulates Manganese-Dependent Cell Toxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9635304/
  65. Jul 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Context-dependent regulation of ferroptosis sensitivity
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    sciencedirect.com/science/article/pii/S2451945622002367
  67. Jun 2022
  68. www.sciencedirect.com www.sciencedirect.com
    Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes
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    sciencedirect.com/science/article/pii/S0092867422006523
  69. Apr 2022
  70. www.sciencedirect.com www.sciencedirect.com
    Sulfur- and phosphorus-standardized metal quantification of biological specimens using inductively coupled plasma mass spectrometry
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  71. Dec 2021
  72. www.sciencedirect.com www.sciencedirect.com
    PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective
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    sciencedirect.com/science/article/pii/S2589004221015418
  73. Nov 2021
  74. www.sciencedirect.com www.sciencedirect.com
    Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs
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  75. Aug 2021
  76. elifesciences.org elifesciences.org
    Quantitative live-cell imaging and computational modeling shed new light on endogenous WNT/CTNNB1 signaling dynamics
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  77. www.biorxiv.org www.biorxiv.org
    Scalable, FACS-Free Genome-Wide Phenotypic Screening
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  78. Jul 2021
  79. www.sciencedirect.com www.sciencedirect.com
    Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
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  80. Jun 2021
  81. www.sciencedirect.com www.sciencedirect.com
    Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin
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  82. May 2021
  83. www.embopress.org www.embopress.org
    A method for benchmarking genetic screens reveals a predominant mitochondrial bias
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  84. Apr 2021
  85. www.sciencedirect.com www.sciencedirect.com
    NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate
    1
    1. scibot 21 Apr 2021
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    sciencedirect.com/science/article/pii/S2211124721003168
  86. Feb 2021
  87. www.sciencedirect.com www.sciencedirect.com
    Targeted degradation of the enhancer lysine acetyltransferases CBP and p300
    1
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    sciencedirect.com/science/article/pii/S2451945620305134
  88. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
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    cell.com/cell/abstract/S0092-8674(20)31627-5
  89. Dec 2020
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
    1
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      DOI: 10.1038/s42255-020-0211-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC7566881/
  91. Oct 2020
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan
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    ncbi.nlm.nih.gov/pmc/articles/PMC7556876/
  93. Sep 2020
  94. www.nature.com www.nature.com
    Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform
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      DOI: 10.1038/s41587-020-0437-z

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    nature.com/articles/s41587-020-0437-z
  95. elifesciences.org elifesciences.org
    p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways
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      DOI: 10.7554/eLife.31723

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    elifesciences.org/articles/31723
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Skd3 (human ClpB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7343390/
  97. Jan 2020
  98. www.nature.com www.nature.com
    High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting
    1
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      DOI: 10.1038/s41551-019-0454-8

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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6289574/
  100. www.sciencedirect.com www.sciencedirect.com
    Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
    1
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    sciencedirect.com/science/article/pii/S2211124719302128
  101. Nov 2018
  102. www.sciencedirect.com www.sciencedirect.com
    Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation
    1
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    sciencedirect.com/science/article/pii/S1097276518303939
  103. www.sciencedirect.com www.sciencedirect.com
    Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread
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    sciencedirect.com/science/article/pii/S1931312817303906
  104. www.sciencedirect.com www.sciencedirect.com
    MLKL Requires the Inositol Phosphate Code to Execute Necroptosis
    1
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    sciencedirect.com/science/article/pii/S1097276518303605
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5832412/
  106. Nov 2017
  107. www.eneuro.org www.eneuro.org
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    eneuro.org/content/4/4/ENEURO.0100-17.2017
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of protein O-mannose kinase reveals a unique active site architecture
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