Hypothesis

26 Matching Annotations

Jun 2025
www.sciencedirect.com www.sciencedirect.com

Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6-mediated gene editing in hematopoietic stem cells

1
1. scibot 04 Jun 2025
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.xcrm.2025.102157
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125002307
Oct 2024
aacrjournals.org aacrjournals.org

YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma

1
1. scibot 02 Oct 2024
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1158/0008-5472.CAN-20-0025
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

aacrjournals.org/cancerres/article/80/21/4741/645935/YAP-Mediated-Repression-of-HRK-Regulates-Tumor
Aug 2024
zh-cn.bio-protocol.org zh-cn.bio-protocol.org

Untitled document

1
1. scibot 02 Aug 2024
  
  in Public
  
  IMSR_ARC:NSG
  
  DOI: 10.21769\u002FBioProtoc.2222
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

zh-cn.bio-protocol.org/CN/e2222
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Identification of cells of leukemic stem cell origin with non-canonical regenerative properties

1
1. scibot 09 Apr 2024
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.xcrm.2024.101485
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379124001319
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia

1
1. scibot 04 Aug 2023
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.xcrm.2023.101108
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10394166/
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pharmaceutical Reactivation of Attenuated Apoptotic Pathways Leads to Elimination of Osimertinib Drug-Tolerant Cells

1
1. scibot 29 Mar 2023
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1158/2767-9764.CRC-22-0066
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10035388/
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation

1
1. scibot 08 Dec 2022
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.celrep.2022.111761
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722016448
Oct 2022
www.sciencedirect.com www.sciencedirect.com

Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells

1
1. scibot 15 Oct 2022
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.stem.2022.09.001
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590922003782
Apr 2022
aacrjournals.org aacrjournals.org

Targeted Therapy of TERT-Rearranged Neuroblastoma with BET Bromodomain Inhibitor and Proteasome Inhibitor Combination Therapy

1
1. scibot 07 Apr 2022
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1158/1078-0432.CCR-20-3044
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

aacrjournals.org/clincancerres/article/27/5/1438/83571/Targeted-Therapy-of-TERT-Rearranged-Neuroblastoma
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Magnesium sensing via LFA-1 regulates CD8+ T cell effector function

1
1. scibot 26 Jan 2022
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.cell.2021.12.039
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867421015610
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Novel colchicine derivative CR42-24 demonstrates potent anti-tumor activity in urothelial carcinoma

1
1. scibot 30 Nov 2021
  
  in Public
  
  RRID:IMSR_ARC
  
  DOI: 10.1016/j.canlet.2021.11.028
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  Curator comments: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJArc Mus musculus IMSR Cat# ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG RRIDCUR:SyntaxError RRIDCUR:Unresolved
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

RRIDCUR:SyntaxError

RRIDCUR:Unresolved

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0304383521006029
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9

1
1. scibot 22 Sep 2021
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.21769/BioProtoc.2222
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8410427/
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Aug 2021
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.stem.2019.02.019
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6458988/
www.sciencedirect.com www.sciencedirect.com

Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells

1
1. scibot 06 Aug 2021
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.stem.2018.10.008
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590918304892
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients

1
1. scibot 17 Mar 2021
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.celrep.2021.108845
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721001595
Feb 2021
www.sciencedirect.com www.sciencedirect.com

Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.xcrm.2021.100202
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379121000136
Aug 2020
www.sciencedirect.com www.sciencedirect.com

Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

1
1. scibot 24 Aug 2020
  
  in Public
  
  RRID:ARC:NSG
  
  DOI: 10.1016/j.stem.2020.02.007
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRIDCUR:Unresolved RRIDCUR:Incorrect RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRIDCUR:Incorrect

RRID:IMSR_ARC:NSG

RRIDCUR:Unresolved

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590920300606
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.molcel.2019.08.028
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276519306835
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  DOI: 10.1016/j.stem.2019.02.019
  
  Resource: (IMSR Cat# ARC_NSG,RRID:IMSR_ARC:NSG)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  What is this?
  
  RRID:IMSR_ARC:NSG RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590919300712
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_ARC:NSG
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_ARC:NSG RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610818303672
bio-protocol.org bio-protocol.org

Efficient Generation of Multi-gene Knockout Cell Lines and ...

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  Resource used:
  
  RRID:IMSR_ARC:NSG
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

bio-protocol.org/e2222
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  Resource used:
  
  RRID:IMSR_ARC:NSG
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5994777/
www.sciencedirect.com www.sciencedirect.com

Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  Resource used:
  
  RRID:IMSR_ARC:NSG
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413118303875
www.sciencedirect.com www.sciencedirect.com

Phenotyping and Target Expression Profiling of CD34+/CD38− and CD34+/CD38+ Stem- and Progenitor cells in Acute Lymphoblastic Leukemia

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_ARC:NSG
  
  Curator: @evieth
  
  Resource used:
  
  RRID:IMSR_ARC:NSG
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_ARC:NSG RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1476558618300885
Nov 2017
zh-cn.bio-protocol.org zh-cn.bio-protocol.org

Untitled document

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_ARC:NSG
  
  Resource used:
  
  RRID:IMSR_ARC:NSG
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

zh-cn.bio-protocol.org/CN/e2222
www.bio-protocol.org www.bio-protocol.org

Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9 —BIO-PROTOCOL

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_ARC:NSG
  
  Resource used:
  
  RRID:IMSR_ARC:NSG
  
  SciCrunch record: RRID:IMSR_ARC:NSG
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_ARC:NSG
Visit annotations in context

Tags

RRID:IMSR_ARC:NSG

Annotators

scibot

URL

bio-protocol.org/e2222