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22 Matching Annotations

Jul 2026
www.sciencedirect.com www.sciencedirect.com

Targeting the MAPK/ERK Signaling Pathway: Mechanistic Analysis of Pexidartinib in Overcoming Adriamycin Resistance in Breast Cancer

1
1. scibot 25 Jul 2026
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1016/j.yexcr.2026.115127
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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scibot

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sciencedirect.com/science/article/pii/S0014482726002442
Apr 2026
www.science.org www.science.org

Patient-derived pediatric brain tumor orthotopic xenografts and tumor organoids faithfully recapitulate primary tumors

1
1. scibot 23 Apr 2026
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1126/sciadv.aea4966
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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scibot

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science.org/doi/10.1126/sciadv.aea4966
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Using TGF-β1 Biology in Radioiodine Refractory Differentiated Thyroid Cancer to Re-establish Sodium Iodide Symporter Expression Using Engineered Mesenchymal Stem Cells as Therapy Vehicles

1
1. scibot 10 Feb 2026
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1016/j.ymthe.2025.10.033
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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RRID:IMSR_CRL:086

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12703174/
Oct 2025
54.241.53.176 54.241.53.176

1-s2.0-S1525001625008548-main-html.html

1
1. scibot 18 Oct 2025
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1016/j.ymthe.2025.10.033
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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RRID:IMSR_CRL:086

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scibot

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54.241.53.176/b5ce306910ec84b6999e97350879f4fb448161d9/1-s2.0-S1525001625008548-main-html.html
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

1
1. scibot 20 Sep 2025
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1158/0008-5472.CAN-25-0351
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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pmc.ncbi.nlm.nih.gov/articles/PMC12434395/
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Analysis of nanomedicine primary tumor vs. metastasis targeting using clinical-stage core-crosslinked polymeric micelles

1
1. scibot 12 Aug 2025
  
  in Public
  
  Charles River LaboratoriesStrain code: 086
  
  DOI: 10.1016/j.celrep.2025.116086
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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scibot

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sciencedirect.com/science/article/pii/S2211124725008575
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Drug prioritization identifies panobinostat as a tailored treatment element for patients with metastatic hepatoblastoma

1
1. scibot 14 Nov 2024
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1186/s13046-024-03221-6
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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RRID:IMSR_CRL:086

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pmc.ncbi.nlm.nih.gov/articles/PMC11556140/
Sep 2024
www.sciencedirect.com www.sciencedirect.com

An ILK/STAT3 pathway controls glioblastoma stem cell plasticity

1
1. scibot 27 Sep 2024
  
  in Public
  
  Strain Code 086
  
  DOI: 10.1016/j.devcel.2024.09.003
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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sciencedirect.com/science/article/pii/S1534580724005318
Feb 2024
www.nature.com www.nature.com

A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1

1
1. scibot 08 Feb 2024
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1038/s41467-024-45067-8
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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scibot

URL

nature.com/articles/s41467-024-45067-8
Jun 2023
aacrjournals.org aacrjournals.org

3D-informed targeting of the Trop-2 signal-activation site drives selective cancer vulnerability

1
1. scibot 08 Jun 2023
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1158/1535-7163.MCT-22-0352
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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RRID:IMSR_CRL:086

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scibot

URL

aacrjournals.org/mct/article/22/6/790/726548/3D-Informed-Targeting-of-the-Trop-2-Signal
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Preclinical Efficacy of the Antibody–Drug Conjugate CLDN6–23-ADC for the Treatment of CLDN6-Positive Solid Tumors

1
1. scibot 03 Jun 2023
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1158/1078-0432.CCR-22-2981
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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ncbi.nlm.nih.gov/pmc/articles/PMC10233360/
May 2022
www.mdpi.com www.mdpi.com

Improved Characteristics of RANKL Immuno-PET Imaging Using Radiolabeled Antibody Fab Fragments

1
1. scibot 10 May 2022
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.3390/pharmaceutics14050939
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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RRID:IMSR_CRL:086

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scibot

URL

mdpi.com/1999-4923/14/5/939
Dec 2021
crc.aacrjournals.org crc.aacrjournals.org

The ADAM17-directed Inhibitory Antibody MEDI3622 Antagonizes Radiotherapy-induced VEGF Release and Sensitizes Non–Small Cell Lung Cancer for RadiotherapyADAM17-mediated Radioresistance

1
1. scibot 28 Dec 2021
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1158/2767-9764.CRC-21-0067
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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RRID:IMSR_CRL:086

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scibot

URL

crc.aacrjournals.org/cancerrescommun/article/1/3/164/665523/The-ADAM17-directed-Inhibitory-Antibody-MEDI3622
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation

1
1. scibot 26 May 2021
  
  in Public
  
  Strain Code:086
  
  DOI: 10.1016/j.celrep.2021.109153
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086 RRIDCUR:Missing
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RRID:IMSR_CRL:086

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC8170441/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Immuno-PET Molecular Imaging of RANKL in Cancer

1
1. scibot 19 May 2021
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.3390/cancers13092166
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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RRID:IMSR_CRL:086

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8124205/
www.sciencedirect.com www.sciencedirect.com

Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1016/j.jconrel.2021.03.015
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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RRID:IMSR_CRL:086

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scibot

URL

sciencedirect.com/science/article/pii/S0168365921001267
www.sciencedirect.com www.sciencedirect.com

DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma

1
1. scibot 05 May 2021
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1016/j.devcel.2020.05.027
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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RRID:IMSR_CRL:086

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scibot

URL

sciencedirect.com/science/article/pii/S1534580720304160
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module

1
1. scibot 06 Sep 2020
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1016/j.celrep.2020.01.024
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_CRL:086
  
  What is this?
  
  RRID:IMSR_CRL:086 RRIDCUR:Validated
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RRID:IMSR_CRL:086

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720300334
www.sciencedirect.com www.sciencedirect.com

Serine Catabolism Feeds NADH when Respiration Is Impaired

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1016/j.cmet.2020.02.017
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_CRL:086
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_CRL:086
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RRID:IMSR_CRL:086

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1550413120301145
Aug 2020
www.sciencedirect.com www.sciencedirect.com

Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance

1
1. scibot 15 Aug 2020
  
  in Public
  
  RRID:IMSR_CRL:086
  
  DOI: 10.1016/j.ccell.2019.12.003
  
  Resource: (IMSR Cat# CRL_086,RRID:IMSR_CRL:086)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_CRL:086
  
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  RRID:IMSR_CRL:086
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URL

sciencedirect.com/science/article/pii/S1535610819305732
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Stable and Potent Selenomab-Drug Conjugates

1
1. scibot 08 Nov 2017
  
  in Public
  
  086
  
  Curator: @Jmenke @bandrow
  
  Resource used:
  
  RRID:IMSR_CRL:086
  
  SciCrunch record: RRID:IMSR_CRL:086
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_CRL:086 RRIDCUR:Missing
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RRID:IMSR_CRL:086

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2451945617300600
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_CRL:086
  
  Curator: @gabimpine
  
  Resource used:
  
  RRID:IMSR_CRL:086
  
  SciCrunch record: RRID:IMSR_CRL:086
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_CRL:086 RRIDCUR:Validated
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RRID:IMSR_CRL:086

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5451210/