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34 Matching Annotations

Sep 2025
www.sciencedirect.com www.sciencedirect.com

Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models

1
1. scibot 19 Sep 2025
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.xcrm.2025.102363
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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sciencedirect.com/science/article/pii/S2666379125004367
www.sciencedirect.com www.sciencedirect.com

Restraint of cancer cell plasticity by spatial homotypic clustering

1
1. scibot 19 Sep 2025
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.ccell.2025.08.009
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1535610825003666
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer

1
1. scibot 07 Sep 2025
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1158/0008-5472.CAN-24-0798
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11875910/
Jul 2025
www.sciencedirect.com www.sciencedirect.com

A STAT3/integrin axis accelerates pancreatic cancer initiation and progression

1
1. scibot 23 Jul 2025
  
  in Public
  
  Charles River Labs088
  
  DOI: 10.1016/j.celrep.2025.116010
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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sciencedirect.com/science/article/pii/S2211124725007818
www.biorxiv.org www.biorxiv.org

Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models

1
1. scibot 01 Jul 2025
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1101/2025.06.18.660406
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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biorxiv.org/content/10.1101/2025.06.18.660406v1
Jun 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 13 Jun 2025
  
  in Public
  
  Strain Code 088
  
  DOI: 10.1038/s44321-025-00254-y
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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52.53.155.43/9a2f79631a0beb40aa09f744c00e5a575573d112/PDF-html.html
May 2025
www.sciencedirect.com www.sciencedirect.com

Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target

1
1. scibot 17 May 2025
  
  in Public
  
  Charles River LaboratoriesStrain #:088
  
  DOI: 10.1016/j.ccell.2025.04.014
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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sciencedirect.com/science/article/pii/S1535610825001734
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting Pancreatic Cancer Cell Stemness by Blocking Fibronectin-Binding Integrins on Cancer-Associated Fibroblasts

1
1. scibot 08 Feb 2025
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1158/2767-9764.CRC-24-0491
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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pmc.ncbi.nlm.nih.gov/articles/PMC11783622/
Jan 2025
www.sciencedirect.com www.sciencedirect.com

The potential of lazertinib and amivantamab combination therapy as a treatment strategy for uncommon EGFR-mutated NSCLC

1
1. scibot 28 Jan 2025
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.xcrm.2025.101929
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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sciencedirect.com/science/article/pii/S2666379125000023
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer

1
1. scibot 21 Dec 2024
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1101/2024.02.20.581056
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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pmc.ncbi.nlm.nih.gov/articles/PMC11601497/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Preclinical Characterization of ARX517, a Site-Specific Stable PSMA-Targeted Antibody–Drug Conjugate for the Treatment of Metastatic Castration-Resistant Prostate Cancer

1
1. scibot 11 Dec 2024
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1158/1535-7163.MCT-23-0927
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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pmc.ncbi.nlm.nih.gov/articles/PMC11612621/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Tumor Microbiome Reacts to Hypoxia and Can Influence Response to Radiation Treatment in Colorectal Cancer

1
1. scibot 12 Jul 2024
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1158/2767-9764.CRC-23-0367
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11234499/
Mar 2024
www.nature.com www.nature.com

GAS41 modulates ferroptosis by anchoring NRF2 on chromatin

1
1. scibot 26 Mar 2024
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1038/s41467-024-46857-w
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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nature.com/articles/s41467-024-46857-w
Feb 2024
www.sciencedirect.com www.sciencedirect.com

PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression

1
1. scibot 08 Feb 2024
  
  in Public
  
  Charles River088
  
  DOI: 10.1016/j.cmet.2024.01.006
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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sciencedirect.com/science/article/pii/S1550413124000056
Apr 2023
www.nature.com www.nature.com

Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy

1
1. scibot 11 Apr 2023
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1038/s41467-023-37617-3
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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nature.com/articles/s41467-023-37617-3
www.sciencedirect.com www.sciencedirect.com

USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities

1
1. scibot 08 Apr 2023
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.xcrm.2023.101007
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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sciencedirect.com/science/article/pii/S2666379123001179
Dec 2022
aacrjournals.org aacrjournals.org

Preclinical evaluation of 225Ac-labeled single-domain antibody for the treatment of HER2pos cancer

1
1. scibot 24 Dec 2022
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1158/1535-7163.MCT-21-1021
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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aacrjournals.org/mct/article/21/12/1835/711142/Preclinical-Evaluation-of-225Ac-Labeled-Single
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Cellular architecture of human brain metastases

1
1. scibot 27 Jan 2022
  
  in Public
  
  Strain Code: 088
  
  DOI: 10.1016/j.cell.2021.12.043
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRIDCUR:Missing RRID:IMSR_CRL:088
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RRID:IMSR_CRL:088

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sciencedirect.com/science/article/pii/S0092867421015658
Aug 2021
elifesciences.org elifesciences.org

Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.7554/eLife.27301
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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elifesciences.org/articles/27301
www.sciencedirect.com www.sciencedirect.com

TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.ccell.2021.07.003
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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sciencedirect.com/science/article/pii/S1535610821003809
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair

1
1. scibot 28 Jul 2021
  
  in Public
  
  088
  
  DOI: 10.1016/j.ccell.2019.01.020
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088 RRIDCUR:Missing
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RRID:IMSR_CRL:088

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sciencedirect.com/science/article/pii/S1535610819300546
May 2021
www.sciencedirect.com www.sciencedirect.com

Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis

1
1. scibot 10 May 2021
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.cell.2021.04.016
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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sciencedirect.com/science/article/pii/S0092867421004955
www.sciencedirect.com www.sciencedirect.com

Hydrogel Network Dynamics Regulate Vascular Morphogenesis

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.stem.2020.08.005
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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sciencedirect.com/science/article/pii/S193459092030401X
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

1
1. scibot 23 Apr 2021
  
  in Public
  
  Strain: 088
  
  DOI: 10.1016/j.ccell.2021.02.016
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRIDCUR:Missing RRID:IMSR_CRL:088
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RRID:IMSR_CRL:088

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sciencedirect.com/science/article/pii/S1535610821001185
Mar 2021
www.sciencedirect.com www.sciencedirect.com

MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage

1
1. scibot 01 Mar 2021
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.ccell.2020.12.010
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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sciencedirect.com/science/article/pii/S1535610820306589
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

1
1. scibot 05 Jan 2021
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.molcel.2020.12.012
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRIDCUR:Validated RRID:IMSR_CRL:088
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sciencedirect.com/science/article/pii/S1097276520309047
Sep 2020
www.sciencedirect.com www.sciencedirect.com

A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.ccell.2020.03.004
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820301057
www.sciencedirect.com www.sciencedirect.com

Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.celrep.2020.107701
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088
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sciencedirect.com/science/article/pii/S2211124720306719
www.sciencedirect.com www.sciencedirect.com

Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.stem.2020.02.001
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRIDCUR:Validated RRID:IMSR_CRL:088
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sciencedirect.com/science/article/pii/S1934590920300540
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.chembiol.2019.05.005
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2451945619301746
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.ccell.2019.04.006
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819302016
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_CRL:088
  
  DOI: 10.1016/j.celrep.2019.03.085
  
  Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_CRL:088
  
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  RRID:IMSR_CRL:088 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719304243
Nov 2017
elifesciences.org elifesciences.org

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:IMSR_CRL:088
  
  Curator: @kaitlinsung
  
  Resource used:
  
  RRID:IMSR_CRL:088
  
  SciCrunch record: RRID:IMSR_CRL:088
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_CRL:088 RRIDCUR:Validated
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RRIDCUR:Validated

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scibot

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elifesciences.org/articles/27713
www.sciencedirect.com www.sciencedirect.com

ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer

1
1. scibot 08 Nov 2017
  
  in Public
  
  Athymic nude miceCharles RiverNu/Nu Strain code:088
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_CRL:088
  
  SciCrunch record: RRID:IMSR_CRL:088
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_CRL:088 RRIDCUR:Missing
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Tags

RRIDCUR:Missing

RRID:IMSR_CRL:088

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S153561081730199X