53 Matching Annotations
  1. Dec 2024
  2. link.springer.com link.springer.com
    Inhibition of CD226 co-stimulation suppresses diabetes development in the NOD mouse by augmenting regulatory T cells and diminishing effector T cell function
    1
    1. scibot 13 Dec 2024
      RRID:IMSR_JAX:001976

      DOI: 10.1007/s00125-024-06329-8

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    link.springer.com/article/10.1007/s00125-024-06329-8
  3. Oct 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling
    1
    1. scibot 03 Oct 2024
      RRID:IMSR_JAX:001976

      DOI: 10.2337/db23-0256

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    ncbi.nlm.nih.gov/pmc/articles/PMC10545554/
  5. Aug 2024
  6. www.sciencedirect.com www.sciencedirect.com
    CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes
    1
    1. scibot 30 Aug 2024
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.immuni.2024.07.024

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    sciencedirect.com/science/article/pii/S107476132400373X
  7. Jul 2024
  8. www.biorxiv.org www.biorxiv.org
    Inhibition of CD226 Co-Stimulation Suppresses Diabetes Development in the NOD Mouse by Augmenting Tregs and Diminishing Effector T Cell Function
    1
    1. scibot 23 Jul 2024
      RRID:IMSR_JAX:001976

      DOI: 10.1101/2024.07.16.603756

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    biorxiv.org/content/10.1101/2024.07.16.603756v1
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans
    1
    1. scibot 18 Jul 2024
      RRID:IMSR_JAX:001976

      DOI: 10.1007/s00125-024-06193-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11410908/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular profiling of NOD mouse islets reveals a novel regulator of insulitis onset
    1
    1. scibot 02 Jul 2024
      RRID:IMSR JAX stock #001976

      DOI: 10.1038/s41598-024-65454-x

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      RRID:IMSR_JAX:001976 DOI:10.1038/s41598-024-65454-x
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    ncbi.nlm.nih.gov/pmc/articles/PMC11199597/
  11. Jun 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Islet cell stress induced by insulin-degrading enzyme deficiency promotes regeneration and protection from autoimmune diabetes
    1
    1. scibot 08 Jun 2024
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.isci.2024.109929

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    sciencedirect.com/science/article/pii/S2589004224011519
  13. www.sciencedirect.com www.sciencedirect.com
    Quantitative trait loci mapping provides insights into the genetic regulation of dendritic cell numbers in mouse tissues
    1
    1. scibot 04 Jun 2024
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.celrep.2024.114296

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    sciencedirect.com/science/article/pii/S2211124724006247
  14. May 2024
  15. www.sciencedirect.com www.sciencedirect.com
    CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity
    1
    1. scibot 16 May 2024
      001976

      DOI: 10.1016/j.immuni.2024.04.017

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      Curator: @abever99

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    sciencedirect.com/science/article/pii/S107476132400222X
  16. Jan 2024
  17. 52.53.155.43 52.53.155.43
    Discordant effects of polyamine depletion by DENSpm and DFMO on β cell cytokine stress and diabetes outcomes in mice
    1
    1. scibot 12 Jan 2024
      JAX:001976

      DOI: 10.1210/endocr/bqae001

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    52.53.155.43/2d936eff3de62abd14c31ac4678d07f195bdd41e/bqae001-html.html
  18. Oct 2023
  19. www.biorxiv.org www.biorxiv.org
    Palatal segment contributions to midfacial growth in three inbred mouse strains
    1
    1. scibot 13 Oct 2023
      RRID:IMSR_JAX:001976

      DOI: 10.1101/2023.10.03.560703

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    biorxiv.org/content/10.1101/2023.10.03.560703v1
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel regulators of islet function identified from genetic variation in mouse islet Ca2+ oscillations
    1
    1. scibot 05 Oct 2023
      RRID:IMSR_JAX:001976

      DOI: 10.7554/eLife.88189

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC10547476/
  21. Sep 2023
  22. link.springer.com link.springer.com
    59 th EASD Annual Meeting of the European Association for the Study of Diabetes
    1
    1. scibot 07 Sep 2023
      JAX:001976

      DOI: 10.1007/s00125-023-05969-6

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    link.springer.com/article/10.1007/s00125-023-05969-6
  23. Jul 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Genetic pathways regulating the longitudinal acquisition of cocaine self-administration in a panel of inbred and recombinant inbred mice
    1
    1. scibot 27 Jul 2023
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.celrep.2023.112856

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    sciencedirect.com/science/article/pii/S2211124723008677
  25. Jun 2023
  26. www.biorxiv.org www.biorxiv.org
    Real Time In vivo Analysis of Pancreatic Beta-cell Autophagic Flux Reveals Impairment Before Onset of Autoimmune Diabetes
    1
    1. scibot 01 Jun 2023
      JAX:001976

      DOI: 10.1101/2023.05.23.541935

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    biorxiv.org/content/10.1101/2023.05.23.541935v1
  27. May 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements
    1
    1. scibot 25 May 2023
      RRID:IMSR_JAX:01976

      DOI: 10.1016/j.xgen.2023.100291

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC10203049/
  29. Feb 2023
  30. www.sciencedirect.com www.sciencedirect.com
    DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development
    1
    1. scibot 17 Feb 2023
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.celrep.2023.112106

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    sciencedirect.com/science/article/pii/S2211124723001171
  31. Jan 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
    1
    1. scibot 05 Jan 2023
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.chom.2022.12.009

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    sciencedirect.com/science/article/pii/S1931312822006102
  33. Nov 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection
    1
    1. scibot 05 Nov 2022
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.celrep.2022.111478

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    sciencedirect.com/science/article/pii/S2211124722013286
  35. Jun 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes
    1
    1. scibot 29 Jun 2022
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.celrep.2022.111011

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    sciencedirect.com/science/article/pii/S2211124722008002
  37. www.sciencedirect.com www.sciencedirect.com
    Genetic background and sex control the outcome of high-fat diet feeding in mice
    1
    1. scibot 15 Jun 2022
      JAX:001976

      DOI: 10.1016/j.isci.2022.104468

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    sciencedirect.com/science/article/pii/S2589004222007398
  38. www.sciencedirect.com www.sciencedirect.com
    Glucagon-receptor-antagonism-mediated β-cell regeneration as an effective anti-diabetic therapy
    1
    1. scibot 03 Jun 2022
      JAX001976

      DOI: 10.1016/j.celrep.2022.110872

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      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S2211124722006477
  39. Mar 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Induction of broadly reactive influenza antibodies increases susceptibility to autoimmunity
    1
    1. scibot 09 Mar 2022
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.celrep.2022.110482

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    sciencedirect.com/science/article/pii/S2211124722002157
  41. Jan 2022
  42. diabetesjournals.org diabetesjournals.org
    Syntaxin 4 enrichment in β-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice
    1
    1. scibot 28 Jan 2022
      JAX:001976

      DOI: 10.2337/db21-0170

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    diabetesjournals.org/diabetes/article/70/12/2837/139076/Syntaxin-4-Enrichment-in-Cells-Prevents-Conversion
  43. www.sciencedirect.com www.sciencedirect.com
    Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation
    1
    1. scibot 16 Jan 2022
      JAX:001976

      DOI: 10.1016/j.celrep.2021.110231

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    sciencedirect.com/science/article/pii/S221112472101740X
  44. Oct 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation
    1
    1. scibot 16 Oct 2021
      Stock No: 001976

      DOI: 10.1016/j.devcel.2021.09.022

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      Curator: @Naa003

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      RRIDCUR:Missing RRID:IMSR_JAX:001976
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    sciencedirect.com/science/article/pii/S1534580721007668
  46. Sep 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Regulation of protein abundance in genetically diverse mouse populations
    1
    1. scibot 04 Sep 2021
      JAX:001976

      DOI: 10.1016/j.xgen.2021.100003

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    sciencedirect.com/science/article/pii/S2666979X21000033
  48. Aug 2021
  49. dom-pubs.onlinelibrary.wiley.com dom-pubs.onlinelibrary.wiley.com
    High fat diet prevents the development of autoimmune diabetes in NOD mice
    1
    1. scibot 16 Aug 2021
      RRID:IMSR_Jax:001976

      DOI: 10.1111/dom.14486

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    dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.14486
  50. academic.oup.com academic.oup.com
    Exocytosis Protein DOC2B as a Biomarker of Type 1 Diabetes
    1
    1. scibot 13 Aug 2021
      RRID:IMSR_JAX:001976

      DOI: 10.1210/jc.2017-02492

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    academic.oup.com/jcem/article/103/5/1966/4916911
  51. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes
    1
    1. scibot 07 Aug 2021
      #001976

      DOI: 10.2337/db20-0845

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    diabetes.diabetesjournals.org/content/70/6/1334
  52. Jul 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention
    1
    1. scibot 31 Jul 2021
      Jackson Laboratories1976

      DOI: 10.1016/j.cmet.2019.12.005

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1550413119306709
  54. link.springer.com link.springer.com
    Phenotypic alterations in pancreatic lymph node stromal cells from human donors with type 1 diabetes and NOD mice
    1
    1. scibot 29 Jul 2021
      Jax #001976

      DOI: 10.1007/s00125-019-04984-w

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    link.springer.com/article/10.1007/s00125-019-04984-w
  55. academic.oup.com academic.oup.com
    Exocytosis Protein DOC2B as a Biomarker of Type 1 Diabetes
    1
    1. scibot 28 Jul 2021
      RRID:IMSR_JAX:001976

      DOI: 10.1210/jc.2017-02492

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    academic.oup.com/jcem/article/103/5/1966/4916911
  56. www.sciencedirect.com www.sciencedirect.com
    Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes
    1
    1. scibot 28 Jul 2021
      NOD/ShiLtJ

      DOI: 10.1016/j.cmet.2019.01.021

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    sciencedirect.com/science/article/pii/S155041311930021X
  57. www.sciencedirect.com www.sciencedirect.com
    Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice
    1
    1. scibot 23 Jul 2021
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.chom.2021.06.014

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    sciencedirect.com/science/article/pii/S1931312821002961
  58. May 2021
  59. www.sciencedirect.com www.sciencedirect.com
    NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes
    1
    1. scibot 26 May 2021
      JAX:001976

      DOI: 10.1016/j.celrep.2021.109176

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    sciencedirect.com/science/article/pii/S2211124721005210
  60. www.sciencedirect.com www.sciencedirect.com
    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
    1
    1. scibot 12 May 2021
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.celrep.2021.109112

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    sciencedirect.com/science/article/pii/S2211124721004460
  61. www.sciencedirect.com www.sciencedirect.com
    Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency
    1
    1. scibot 09 May 2021
      JAX:001976

      DOI: 10.1016/j.stem.2020.07.005

      Resource: (IMSR Cat# JAX_001976,RRID:IMSR_JAX:001976)

      Curator: @scibot

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      RRID:IMSR_JAX:001976
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    sciencedirect.com/science/article/pii/S193459092030343X
  62. Apr 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP
    1
    1. scibot 01 Apr 2021
      JAX:001976

      DOI: 10.1016/j.celrep.2021.108919

      Resource: (IMSR Cat# JAX_001976,RRID:IMSR_JAX:001976)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:001976

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      RRID:IMSR_JAX:001976 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124721002333
  64. Feb 2021
  65. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 25 Feb 2021
      RRID:IMSR_JAX:001976

      DOI: 10.1111/bph.15058

      Resource: (IMSR Cat# JAX_001976,RRID:IMSR_JAX:001976)

      Curator: @scibot

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      RRID:IMSR_JAX:001976
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15058
  66. www.sciencedirect.com www.sciencedirect.com
    Dynamic Interstitial Cell Response during Myocardial Infarction Predicts Resilience to Rupture in Genetically Diverse Mice
    1
    1. scibot 13 Feb 2021
      JAX:001976

      DOI: 10.1016/j.celrep.2020.02.008

      Resource: (IMSR Cat# JAX_001976,RRID:IMSR_JAX:001976)

      Curator: @ethanbadger

      SciCrunch record: RRID:IMSR_JAX:001976

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      RRIDCUR:Validated RRID:IMSR_JAX:001976
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    sciencedirect.com/science/article/pii/S2211124720301625
  67. Jan 2021
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models
    1
    1. scibot 14 Jan 2021
      RRID:IMSR_JAX:001976

      DOI: 10.26508/lsa.202000952

      Resource: (IMSR Cat# JAX_001976,RRID:IMSR_JAX:001976)

      Curator: @evieth

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      RRIDCUR:Validated RRID:IMSR_JAX:001976
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    ncbi.nlm.nih.gov/pmc/articles/PMC7772779/
  69. Oct 2020
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation
    1
    1. scibot 07 Oct 2020
      RRID:IMSR_JAX:001976

      DOI: 10.3389/fimmu.2020.02180

      Resource: (IMSR Cat# JAX_001976,RRID:IMSR_JAX:001976)

      Curator: @evieth

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      RRIDCUR:Validated RRID:IMSR_JAX:001976
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    ncbi.nlm.nih.gov/pmc/articles/PMC7500101/
  71. Sep 2020
  72. www.sciencedirect.com www.sciencedirect.com
    Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression
    1
    1. scibot 14 Sep 2020
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.immuni.2020.01.003

      Resource: (IMSR Cat# JAX_001976,RRID:IMSR_JAX:001976)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:001976 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761320300303
  73. www.sciencedirect.com www.sciencedirect.com
    An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint
    1
    1. scibot 04 Sep 2020
      NOD

      DOI: 10.1016/j.cell.2020.04.030

      Resource: (IMSR Cat# JAX_001976,RRID:IMSR_JAX:001976)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:001976
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    sciencedirect.com/science/article/pii/S0092867420304931
  74. www.sciencedirect.com www.sciencedirect.com
    Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch
    1
    1. scibot 04 Sep 2020
      Jackson LabsStrain Code: 001976

      DOI: 10.1016/j.celrep.2020.03.036

      Resource: (IMSR Cat# JAX_001976,RRID:IMSR_JAX:001976)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:001976
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    sciencedirect.com/science/article/pii/S2211124720303508
  75. Jan 2020
  76. www.sciencedirect.com www.sciencedirect.com
    Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:001976

      DOI: 10.1016/j.celrep.2019.11.010

      Resource: (IMSR Cat# JAX_001976,RRID:IMSR_JAX:001976)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:001976 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719314810
  77. Nov 2018
  78. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:001976

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      RRID:IMSR_JAX:001976

      SciCrunch record: RRID:IMSR_JAX:001976

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      RRID:IMSR_JAX:001976
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    sciencedirect.com/science/article/pii/S155041311830576X
  79. www.sciencedirect.com www.sciencedirect.com
    Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes
    1
    1. scibot 05 Nov 2018
      001976

      Curator: @Jmenke

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      RRID:IMSR_JAX:001976

      SciCrunch record: RRID:IMSR_JAX:001976

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      RRID:IMSR_JAX:001976 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1550413118303942
  80. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:001976

      Curator: @Jmenke

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      RRID:IMSR_JAX:001976

      SciCrunch record: RRID:IMSR_JAX:001976

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      RRID:IMSR_JAX:001976 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2451945617304622
  81. onlinelibrary.wiley.com onlinelibrary.wiley.com
    “Epigenetic control of early neurodegenerative events in Diabetic Retinopathy by the histone deacetylase SIRT6”
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:001976

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      RRID:IMSR_JAX:001976

      SciCrunch record: RRID:IMSR_JAX:001976

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      RRID:IMSR_JAX:001976
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14243/full
  82. www.sciencedirect.com www.sciencedirect.com
    Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:001976

      Resource used:

      RRID:IMSR_JAX:001976

      SciCrunch record: RRID:IMSR_JAX:001976

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      RRID:IMSR_JAX:001976
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    sciencedirect.com/science/article/pii/S0092867417314319
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:001976

      Curator: @evieth

      Resource used:

      RRID:IMSR_JAX:001976

      SciCrunch record: RRID:IMSR_JAX:001976

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:IMSR_JAX:001976 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5728720/