530 Matching Annotations
  1. Oct 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lung cancer–intrinsic SOX2 expression mediates resistance to checkpoint blockade therapy by inducing Treg cell–dependent CD8+ T-cell exclusion
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964848/
  3. www.sciencedirect.com www.sciencedirect.com
    Retinoic acid and ascorbate synergize to suppress myeloid leukemia via TET2 activation
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    sciencedirect.com/science/article/pii/S2211124725011507
  4. Sep 2025
  5. www.sciencedirect.com www.sciencedirect.com
    Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4
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    sciencedirect.com/science/article/pii/S1074761325004145
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    IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation
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    sciencedirect.com/science/article/pii/S2211124725011015
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    CD7 regulates the persistence of terminally exhausted CD8+ T cells during chronic infection
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    sciencedirect.com/science/article/pii/S2211124725010873
  8. www.sciencedirect.com www.sciencedirect.com
    Computational tracking of cell origins using CellSexID from single-cell transcriptomes
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    sciencedirect.com/science/article/pii/S2667237525002176
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    T cell-intrinsic cGAS-CTCF regulation maintains regulatory T cell development and function
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    sciencedirect.com/science/article/pii/S2211124725010733
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    Protocol for noninvasive imaging of hematopoietic reconstitution in live mice using Akaluc bioluminescence
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    sciencedirect.com/science/article/pii/S2666166725004782
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    Phenotypic pleiotropy of missense variants in human B cell confinement receptor P2RY8
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    sciencedirect.com/science/article/pii/S2666979X2500237X
  12. www.biorxiv.org www.biorxiv.org
    LCK deficiency in CD8 T cells leads to reduced proliferation and increased effector T-cell formation in mice
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    biorxiv.org/content/10.1101/2025.08.28.672860v1
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Assessing the impact of TET2 and TET3 deletion in TCRalpha and TCRbeta repertoire in murine CD4 T cells in physiological and pathophysiological conditions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405334/
  14. www.biorxiv.org www.biorxiv.org
    Plasmacytoid dendritic cells in the intestine preferentially produce interferon lambda at homeostasis contributing to tonic localized innate immune responses
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    biorxiv.org/content/10.1101/2025.08.25.672167v1
  15. Aug 2025
  16. insight.jci.org insight.jci.org
    Targeting pyruvate metabolism generates distinct CD8+ T cell responses to gammaherpesvirus and B lymphoma
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    insight.jci.org/articles/view/187680
  17. www.sciencedirect.com www.sciencedirect.com
    Distinct roles for NF-κB in hematopoietic stem cells and the bone marrow milieu in promoting hematopoietic aging
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    sciencedirect.com/science/article/pii/S2211124725009647
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    Lymphoma accelerates T cell and tissue aging
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    sciencedirect.com/science/article/pii/S1535610825003290
  19. www.biorxiv.org www.biorxiv.org
    IFNG-producing self-reactive CD4+ T cells drive autoimmune adrenalitis in a mouse model of Addison’s disease
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    biorxiv.org/content/10.1101/2025.08.11.669305v2
  20. academic.oup.com academic.oup.com
    Diet-induced obesity induces oxidative stress and enhances H3K4me3 levels, driving nonresolving inflammation and myelopoiesis in hematopoietic stem and progenitor cells
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    academic.oup.com/jimmunol/advance-article/doi/10.1093/jimmun/vkaf156/8226666
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CTG-Initiated Cryptic Peptide Translation Up- and Downstream of a Canonical ATG Start Codon Is Enhanced by TLR Stimulation and Induces Tumor Regression in Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314520/
  22. www.sciencedirect.com www.sciencedirect.com
    Stress-induced glucocorticoids enhance acute inflammation by promoting the differentiation of Th17 cells
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    sciencedirect.com/science/article/pii/S2211124725008642
  23. www.sciencedirect.com www.sciencedirect.com
    Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells
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    sciencedirect.com/science/article/pii/S1074761325003176
  24. Jul 2025
  25. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
  26. www.science.org www.science.org
    Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate
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    science.org/doi/10.1126/sciimmunol.ado3032
  27. www.sciencedirect.com www.sciencedirect.com
    Adoptively transferred Th17 cells cooperate with host B cells to achieve durable tumor immunity
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    sciencedirect.com/science/article/pii/S1535610825002727
  28. academic.oup.com academic.oup.com
    Refined cell transfer model reveals roles for Ascl2 and Cxcr3 in splenic localization of mouse NK cells during virus infection
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    academic.oup.com/jimmunol/advance-article/doi/10.1093/jimmun/vkaf122/8210553
  29. www.sciencedirect.com www.sciencedirect.com
    Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity
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    sciencedirect.com/science/article/pii/S1074761325002870
  30. www.biorxiv.org www.biorxiv.org
    Inflammaging in aged tissues drives remodeling of the CD8+ T cell compartment
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    biorxiv.org/content/10.1101/2025.07.11.664388v1
  31. www.sciencedirect.com www.sciencedirect.com
    TAF1 is required for fetal but not adult hematopoiesis in mice
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    sciencedirect.com/science/article/pii/S1534580725004058
  32. www.sciencedirect.com www.sciencedirect.com
    Cognate interaction-dependent pathogenicity of meningeal B cells drives neuroinflammation relapse
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    sciencedirect.com/science/article/pii/S1074761325002857
  33. www.sciencedirect.com www.sciencedirect.com
    BLIMP1 controls GC B cell expansion and exit through regulating cell cycle progression and key transcription factors BCL6 and IRF4
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    sciencedirect.com/science/article/pii/S221112472500748X
  34. www.biorxiv.org www.biorxiv.org
    Improved conditioning for hematopoietic chimerism induces islet tolerance to cure diabetes
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    biorxiv.org/content/10.1101/2025.06.26.661773v1
  35. www.sciencedirect.com www.sciencedirect.com
    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002481
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps
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    pmc.ncbi.nlm.nih.gov/articles/PMC12201663/
  37. Jun 2025
  38. www.pnas.org www.pnas.org
    Mutant <i>IDH1</i> cooperates with <i>NPM1c</i> or <i>FLT3</i><sup>ITD</sup> to drive distinct myeloid diseases and molecular outcomes
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    pnas.org/doi/abs/10.1073/pnas.2415779122
  39. rupress.org rupress.org
    BCOR and ZC3H12A suppress a core stemness program in exhausted CD8+ T cells
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    rupress.org/jem/article/222/8/e20241133/277913/BCOR-and-ZC3H12A-suppress-a-core-stemness-program
  40. www.sciencedirect.com www.sciencedirect.com
    A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiency
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    sciencedirect.com/science/article/pii/S2211124725006734
  41. www.biorxiv.org www.biorxiv.org
    Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment
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    biorxiv.org/content/10.1101/2023.03.13.532431v1
  42. www.science.org www.science.org
    CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity
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    science.org/doi/10.1126/sciimmunol.adq8860
  43. www.sciencedirect.com www.sciencedirect.com
    Targeting microglial PPARα ameliorates the outcome of ischemic stroke by enhancing interaction with infiltrating peripheral monocytes/macrophages
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    sciencedirect.com/science/article/pii/S2211124725006461
  44. www.sciencedirect.com www.sciencedirect.com
    Bivalent chromatin instructs lineage specification during hematopoiesis
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    sciencedirect.com/science/article/pii/S0092867425005616
  45. www.sciencedirect.com www.sciencedirect.com
    ILC3s sense gut microbiota through STING to initiate immune tolerance
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    sciencedirect.com/science/article/pii/S1074761325002377
  46. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/222b3bee495041e065bdee761a6ce36008a4c9e7/PDF-html.html
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
  48. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225010612-main-html.html
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    52.53.155.43/f34824e88c5d24b65878b735b4d1d5b775fb7497/1-s2.0-S2589004225010612-main-html.html
  49. www.sciencedirect.com www.sciencedirect.com
    Distinct TAM subset with cross-dressing capability determines the bifurcation of tumor immunity
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    sciencedirect.com/science/article/pii/S2211124725005716
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor-associated neutrophils attenuate the immunosensitivity of hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11619716/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
  52. May 2025
  53. www.sciencedirect.com www.sciencedirect.com
    Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1535610825002119
  54. www.sciencedirect.com www.sciencedirect.com
    A CD4+ T cell-intrinsic complement C5aR2-prostacyclin-IL-1R2 axis orchestrates Th1 cell contraction
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    sciencedirect.com/science/article/pii/S1074761325002225
  55. www.sciencedirect.com www.sciencedirect.com
    Protocol for in vivo lineage tracing of regeneration-associated macrophages from injured skeletal muscle of adult mice
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    sciencedirect.com/science/article/pii/S2666166725002503
  56. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
  57. www.sciencedirect.com www.sciencedirect.com
    Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis
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    sciencedirect.com/science/article/pii/S0092867425005021
  58. www.sciencedirect.com www.sciencedirect.com
    Protocol for assessing mobilization of peritoneal B cells to the pre-metastatic omentum in an orthotopic mouse model of ovarian cancer
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    sciencedirect.com/science/article/pii/S2666166725002126
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAG suppresses group 2 innate lymphoid cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12055012/
  60. www.sciencedirect.com www.sciencedirect.com
    Somatic hypermutation unlocks antibody specificities beyond the primary repertoire
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    sciencedirect.com/science/article/pii/S1074761325001773
  61. www.sciencedirect.com www.sciencedirect.com
    Immunotherapy-related cognitive impairment after CAR T cell therapy in mice
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    sciencedirect.com/science/article/pii/S0092867425003915
  62. www.sciencedirect.com www.sciencedirect.com
    Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages
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    sciencedirect.com/science/article/pii/S2211124725003948
  63. Apr 2025
  64. www.sciencedirect.com www.sciencedirect.com
    Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes
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    sciencedirect.com/science/article/pii/S2211124725003420
  65. www.biorxiv.org www.biorxiv.org
    TTLL4 glutamyltransferase is a therapeutic target for NPM1-mutated acute myeloid leukemia
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    biorxiv.org/content/10.1101/2025.04.07.647605v1
  66. www.biorxiv.org www.biorxiv.org
    Refined cell transfer model reveals roles for Ascl2 and Cxcr3 in splenic localization of mouse NK cells during virus infection
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    biorxiv.org/content/10.1101/2025.04.05.647391v1
  67. www.sciencedirect.com www.sciencedirect.com
    Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens
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    sciencedirect.com/science/article/pii/S0092867425002934
  68. www.sciencedirect.com www.sciencedirect.com
    Protocol for investigating the impact of transcription regulator deficiency on tumor-specific CD8+ T cell responses via adoptive cell transfer
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    sciencedirect.com/science/article/pii/S2666166725001091
  69. www.sciencedirect.com www.sciencedirect.com
    The metabolic sensor LKB1 regulates ILC3 homeostasis and mitochondrial function
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    sciencedirect.com/science/article/pii/S221112472500227X
  70. Mar 2025
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints
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    pmc.ncbi.nlm.nih.gov/articles/PMC11838595/
  72. www.sciencedirect.com www.sciencedirect.com
    An interleukin-9-ZBTB18 axis promotes germinal center development of memory B cells
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    sciencedirect.com/science/article/pii/S1074761325000883
  73. www.sciencedirect.com www.sciencedirect.com
    PAI-1-driven SFRP2high cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy
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    sciencedirect.com/science/article/pii/S1535610825000765
  74. www.cell.com www.cell.com
    Metabolic engineering to facilitate anti-tumor immunity
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    cell.com/cancer-cell/abstract/S1535-6108(25)00056-X
  75. Feb 2025
  76. www.sciencedirect.com www.sciencedirect.com
    Innate immune training of osteoclastogenesis promotes inflammatory bone loss in mice
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    sciencedirect.com/science/article/pii/S1534580725000632
  77. www.sciencedirect.com www.sciencedirect.com
    PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1
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    sciencedirect.com/science/article/pii/S1934590925000104
  78. www.sciencedirect.com www.sciencedirect.com
    Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response
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    sciencedirect.com/science/article/pii/S2211124725001056
  79. aacrjournals.org aacrjournals.org
    Activation of the cGAS/STING axis in genome-damaged hematopoietic cells does not impact blood cell formation or leukemogenesis
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    aacrjournals.org/cancerres/article/83/17/2858/728589/Activation-of-the-cGAS-STING-Axis-in-Genome
  80. www.sciencedirect.com www.sciencedirect.com
    Distinct plasmablast developmental intermediates produce graded expression of IgM secretory transcripts
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    sciencedirect.com/science/article/pii/S2211124725000543
  81. 52.53.155.43 52.53.155.43
    Different signaling interpretations by PKC eta and theta control T cell function and exhaustion
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    52.53.155.43/9f90de74dc5bf358748b9367775e021d8c3b69fa/2024.09.26.615103v1.full-html.html
  82. www.sciencedirect.com www.sciencedirect.com
    Recirculating regulatory T cells mediate thymic regeneration through amphiregulin following damage
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    sciencedirect.com/science/article/pii/S1074761325000317
  83. Jan 2025
  84. www.sciencedirect.com www.sciencedirect.com
    Progenitor effect in the spleen drives early recovery via universal hematopoietic cell inflation
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    sciencedirect.com/science/article/pii/S2211124725000129
  85. www.sciencedirect.com www.sciencedirect.com
    Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection
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    sciencedirect.com/science/article/pii/S1931312824004840
  86. www.science.org www.science.org
    Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis
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    science.org/doi/10.1126/sciimmunol.adl4909
  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mechanical Force-Induced cGAS Activation in Carcinoma Cells Facilitates Splenocytes into Liver to Drive Metastasis
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    onlinelibrary.wiley.com/doi/10.1002/advs.202401127
  88. www.sciencedirect.com www.sciencedirect.com
    Bone marrow mesenchymal stromal cells support translation in refractory acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S221112472401502X
  89. www.sciencedirect.com www.sciencedirect.com
    A minority of Th1 and Tfh effector cells express survival genes shared by memory cell progeny that require IL-7 or TCR signaling to persist
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    sciencedirect.com/science/article/pii/S2211124724014621
  90. www.sciencedirect.com www.sciencedirect.com
    Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10
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    sciencedirect.com/science/article/pii/S1535610824004793
  91. Dec 2024
  92. www.sciencedirect.com www.sciencedirect.com
    Antigen presentation by tumor-associated macrophages drives T cells from a progenitor exhaustion state to terminal exhaustion
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    sciencedirect.com/science/article/pii/S1074761324005417
  93. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SIKs regulate HDAC7 stabilization and cytokine recall in late-stage T cell effector differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC10842463/
  94. www.sciencedirect.com www.sciencedirect.com
    Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes
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    sciencedirect.com/science/article/pii/S0092867424013473
  95. www.sciencedirect.com www.sciencedirect.com
    Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia
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    sciencedirect.com/science/article/pii/S2211124724014074
  96. www.nature.com www.nature.com
    Concomitant loss of TET2 and TET3 results in T cell expansion and genomic instability in mice
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    nature.com/articles/s42003-024-07312-0
  97. www.sciencedirect.com www.sciencedirect.com
    EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function
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    sciencedirect.com/science/article/pii/S1535610824004410
  98. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism
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  107. Oct 2024
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    IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis
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  201. Nov 2023
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    Induction of immortal-like and functional CAR-T cells by defined factors
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    ABIN1 is a negative regulator of effector functions in cytotoxic T cells
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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target
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  205. www.science.org www.science.org
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  206. Oct 2023
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    Antigen presentation by tumor-associated macrophages mediates progenitor to terminal exhaustion transition in GBM and other solid tumors
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    The Transcription Factor IRF4 Determines the Anti-Tumor Immunity of CD8+ T cells
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  209. Sep 2023
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    ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control
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  215. Aug 2023
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    The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function
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