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47 Matching Annotations

May 2026
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Tissue tension fosters macrophage-driven lipid peroxidation-induced DNA damage

1
1. scibot 01 May 2026
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.ccell.2026.03.022
  
  Resource: RRID:IMSR_JAX:002101
  
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sciencedirect.com/science/article/pii/S1535610826001765
Apr 2026
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An autochthonous CRISPR activation screening platform for characterizing tissue-specific oncogene selection

1
1. scibot 18 Apr 2026
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.xcrm.2026.102759
  
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sciencedirect.com/science/article/pii/S266637912600176X
Feb 2026
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Male-biased Yap1-Cd276/B7-H3 axis for immune evasion in medulloblastoma

1
1. scibot 06 Feb 2026
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.ccell.2026.01.005
  
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sciencedirect.com/science/article/pii/S1535610826000449
Dec 2025
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Cse1l is critical for cell survival, craniofacial and cardiac development

1
1. scibot 14 Dec 2025
  
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  JAX:002101
  
  DOI: 10.1016/j.ydbio.2025.12.007
  
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sciencedirect.com:5037/science/article/pii/S0012160625003380
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Long noncoding RNA-dependent control of Myc transcriptional bursting

1
1. scibot 22 Oct 2025
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.celrep.2025.116439
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12606467/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

p21, ccng1, foxo3b, and fbxw7 contribute to p53-dependent cell cycle arrest

1
1. scibot 17 May 2025
  
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  Jackson Labs002101
  
  DOI: 10.1016/j.isci.2025.112558
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12145846/
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Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target

1
1. scibot 17 May 2025
  
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  The Jackson LaboratoryStrain #:002101
  
  DOI: 10.1016/j.ccell.2025.04.014
  
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sciencedirect.com/science/article/pii/S1535610825001734
Mar 2025
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A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies

1
1. scibot 28 Mar 2025
  
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  JAX:002101
  
  DOI: 10.1016/j.ccell.2025.03.007
  
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sciencedirect.com/science/article/pii/S1535610825001084
Jan 2025
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The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway

1
1. scibot 24 Jan 2025
  
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  Jackson Laboratory Cat_002101
  
  DOI: 10.1016/j.celrep.2025.115231
  
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  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:002101
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sciencedirect.com/science/article/pii/S2211124725000026
Nov 2024
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A platform of functional studies of ESCC-associated gene mutations identifies the roles of TGFBR2 in ESCC progression and metastasis

1
1. scibot 17 Nov 2024
  
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  Cat# N0002101
  
  DOI: 10.1016/j.celrep.2024.114952
  
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sciencedirect.com/science/article/pii/S2211124724013032
Sep 2024
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Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes

1
1. scibot 27 Sep 2024
  
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  #002101
  
  DOI: 10.1016/j.ydbio.2024.09.007
  
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sciencedirect.com/science/article/pii/S0012160624002343
Aug 2024
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The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton

1
1. scibot 27 Aug 2024
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.celrep.2024.114666
  
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sciencedirect.com/science/article/pii/S2211124724010179
52.53.155.43 52.53.155.43

Treatment of RB1-intact hepatocellular carcinoma with CDK4/6 inhibitor combination therapy

1
1. scibot 02 Aug 2024
  
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  Stock No. 002101
  
  DOI: 10.1002/hep.31872
  
  Resource: RRID:IMSR_JAX:002101
  
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  RRIDCUR:Missing RRID:IMSR_JAX:002101
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52.53.155.43/d535e061bd39448f0bff90d2d8bad0476300ef0d/hep.31872 (1)-html.html
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On the role of p53 in the cellular response to aneuploidy

1
1. scibot 01 Aug 2024
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.celrep.2021.108892
  
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  RRIDCUR:Validated RRID:IMSR_JAX:002101
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sciencedirect.com/science/article/pii/S2211124721002060
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle

1
1. scibot 16 Jul 2024
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.devcel.2020.07.005
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7606764/
Nov 2023
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Extensive elimination of acinar cells during normal postnatal pancreas growth

1
1. scibot 28 Nov 2023
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.celrep.2023.113457
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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sciencedirect.com/science/article/pii/S2211124723014699
Sep 2023
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20 kDa isoform of connexin-43 augments spatial reorganization of the brain endothelial junctional complex and lesion leakage in cerebral cavernous malformation type-3

1
1. scibot 01 Sep 2023
  
  in Public
  
  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.nbd.2023.106277
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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sciencedirect.com/science/article/pii/S0969996123002929
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates

1
1. scibot 04 Jul 2023
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.7554/eLife.78695
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10313321/
May 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition

1
1. scibot 10 May 2023
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1002/advs.202206098
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202206098
Mar 2023
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In vivo RNA-seq and ChIP-seq analyses show an obligatory role for the C terminus of p53 in conferring tissue-specific radiation sensitivity

1
1. scibot 16 Mar 2023
  
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  JAX:002101
  
  DOI: 10.1016/j.celrep.2023.112216
  
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sciencedirect.com/science/article/pii/S2211124723002279
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors

1
1. scibot 25 Jan 2023
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1158/2767-9764.crc-22-0124
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9853917/
Nov 2022
aacrjournals.org aacrjournals.org

A druggable UHRF1/DNMT1/GLI complex regulates Sonic hedgehog dependent tumor growth

1
1. scibot 22 Nov 2022
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1158/1541-7786.MCR-22-0182
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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aacrjournals.org/mcr/article/20/11/1598/709855/A-Druggable-UHRF1-DNMT1-GLI-Complex-Regulates
Oct 2022
52.53.155.43 52.53.155.43

mcr-22-0182-html.html

1
1. scibot 29 Oct 2022
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.1158/1541-7786.MCR-22-0182
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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52.53.155.43/736c3e45aba95f2b9e7e9af3df073f3bca899f3f/mcr-22-0182-html.html
Jun 2022
aacrjournals.org aacrjournals.org

Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors

1
1. scibot 15 Jun 2022
  
  in Public
  
  RRID:IMSR_JAX:002101
  
  DOI: 10.1158/2767-9764.CRC-22-0124
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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aacrjournals.org/cancerrescommun/article/2/6/402/699311/Cancer-Stem-Cells-not-Bulk-Tumor-Cells-Determine
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer

1
1. scibot 04 Feb 2022
  
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  JAX:002101
  
  DOI: 10.1016/j.ccell.2022.01.004
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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sciencedirect.com/science/article/pii/S153561082200006X
Dec 2021
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Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity

1
1. scibot 21 Dec 2021
  
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  Jax stock 002101
  
  DOI: 10.1016/j.devcel.2021.11.020
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:IMSR_JAX:002101
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sciencedirect.com/science/article/pii/S1534580721009448
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Isolation of myeloid cells from mouse brain tumors for single-cell RNA-seq analysis

1
1. scibot 18 Nov 2021
  
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  002101
  
  DOI: 10.1016/j.xpro.2021.100957
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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  RRIDCUR:Missing RRID:IMSR_JAX:002101
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sciencedirect.com/science/article/pii/S2666166721006638
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development

1
1. scibot 25 Sep 2021
  
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  RRID:IMSR_JAX:002101
  
  DOI: 10.7554/eLife.67989
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8456695/
Aug 2021
52.53.155.43 52.53.155.43

hep.31872-html.html

1
1. scibot 13 Aug 2021
  
  in Public
  
  Stock No. 002101
  
  DOI: 10.1002/HEP.31872
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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52.53.155.43/9141f02023b9cd2a20a0ded8540f4e4d455d9808/hep.31872-html.html
Jul 2021
insight.jci.org insight.jci.org

Disruption of Robo2-Baiap2 integrated signaling drives cystic disease

1
1. scibot 31 Jul 2021
  
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  002101
  
  DOI: 10.1172/jci.insight.127602
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
  Curator: @bandrow
  
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  RRID:IMSR_JAX:002101 RRIDCUR:Missing
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insight.jci.org/articles/view/127602
May 2021
www.sciencedirect.com www.sciencedirect.com

An anterograde pathway for sensory axon degeneration gated by a cytoplasmic action of the transcriptional regulator P53

1
1. scibot 11 May 2021
  
  in Public
  
  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.devcel.2021.03.011
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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sciencedirect.com/science/article/pii/S1534580721002082
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle

1
1. scibot 05 May 2021
  
  in Public
  
  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.devcel.2020.07.005
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7606764/
Apr 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)

1
1. scibot 24 Apr 2021
  
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  JAX:002101
  
  DOI: 10.1016/j.cell.2020.12.025
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7886018/
www.sciencedirect.com www.sciencedirect.com

MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism

1
1. scibot 22 Apr 2021
  
  in Public
  
  002101
  
  DOI: 10.1016/j.ccell.2021.02.006
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
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  RRIDCUR:Missing RRID:IMSR_JAX:002101
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RRID:IMSR_JAX:002101

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scibot

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sciencedirect.com/science/article/pii/S1535610821001082
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Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality

1
1. scibot 01 Apr 2021
  
  in Public
  
  002101
  
  DOI: 10.1016/j.celrep.2021.108917
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
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  RRIDCUR:Missing RRID:IMSR_JAX:002101
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RRID:IMSR_JAX:002101

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sciencedirect.com/science/article/pii/S221112472100231X
Mar 2021
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On the role of p53 in the cellular response to aneuploidy

1
1. scibot 24 Mar 2021
  
  in Public
  
  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.celrep.2021.108892
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
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  RRID:IMSR_JAX:002101
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sciencedirect.com/science/article/pii/S2211124721002060
Feb 2021
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Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype

1
1. scibot 11 Feb 2021
  
  in Public
  
  Stock No: 002101
  
  DOI: 10.1016/j.celrep.2021.108726
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
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  RRID:IMSR_JAX:002101 RRIDCUR:Missing
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RRID:IMSR_JAX:002101

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sciencedirect.com/science/article/pii/S2211124721000395
Sep 2020
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Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX#002101
  
  DOI: 10.1016/j.cell.2019.12.024
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
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  RRID:IMSR_JAX:002101
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sciencedirect.com/science/article/pii/S0092867419313868
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A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic Activity of p53

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX 002101
  
  DOI: 10.1016/j.celrep.2019.12.074
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
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  RRID:IMSR_JAX:002101 RRIDCUR:Missing
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RRID:IMSR_JAX:002101

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scibot

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sciencedirect.com/science/article/pii/S2211124719317395
Jan 2020
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Breakage-Fusion-Bridge Events Trigger Complex Genome Rearrangements and Amplifications in Developmentally Arrested T Cell Lymphomas

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.celrep.2019.05.014
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
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  RRID:IMSR_JAX:002101 RRIDCUR:Validated
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RRID:IMSR_JAX:002101

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scibot

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sciencedirect.com/science/article/pii/S2211124719306254
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Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:002101
  
  DOI: 10.1016/j.celrep.2018.12.089
  
  Resource: (IMSR Cat# JAX_002101,RRID:IMSR_JAX:002101)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
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  RRID:IMSR_JAX:002101 RRIDCUR:Validated
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RRID:IMSR_JAX:002101

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scibot

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sciencedirect.com/science/article/pii/S2211124718320497
Nov 2018
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Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion

1
1. scibot 05 Nov 2018
  
  in Public
  
  002101
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:002101
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:002101 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S153561081830309X
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A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:002101
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:002101
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:002101 RRIDCUR:Validated
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RRID:IMSR_JAX:002101

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sciencedirect.com/science/article/pii/S0092867418301090
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Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:002101
  
  Curator: @anp055
  
  Resource used:
  
  RRID:IMSR_JAX:002101
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:002101 RRIDCUR:Validated
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RRID:IMSR_JAX:002101

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sciencedirect.com/science/article/pii/S1074761317305721
Nov 2017
academic.oup.com academic.oup.com

Tributyltin Alters the Bone Marrow Microenvironment and Suppresses B Cell Development

2
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:IMSR_JAX:002101
  
  Curator: @bandrow
  
  Resource used:
  
  RRID:IMSR_JAX:002101
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:002101
2. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:002101
  
  Curator: @chewbeccax
  
  Resource used:
  
  RRID:IMSR_JAX:002101
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:002101 RRIDCUR:Validated
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RRID:IMSR_JAX:002101

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academic.oup.com/toxsci/article/doi/10.1093/toxsci/kfx067/3112579/Tributyltin-Alters-the-Bone-Marrow
www.sciencedirect.com www.sciencedirect.com

Axonal Degeneration Is Regulated by a Transcriptional Program that Coordinates Expression of Pro- and Anti-degenerative Factors

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:002101
  
  Curator: @chewbeccax
  
  Resource used:
  
  RRID:IMSR_JAX:002101
  
  SciCrunch record: RRID:IMSR_JAX:002101
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:002101 RRIDCUR:Validated
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RRID:IMSR_JAX:002101

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scibot

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sciencedirect.com/science/article/pii/S0896627316308352