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Deficiency of protein kinase Cδ reprograms macrophage immunometabolism to suppress pyroptosis and stabilize atherosclerotic plaques

1
1. scibot 16 Sep 2026
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1038/s12276-026-01842-9
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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nature.com/articles/s12276-026-01842-9
Sep 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nanoparticle-Enabled Plasma Proteomics of Experimental Atherosclerosis in Mice

1
1. scibot 01 Sep 2026
  
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  JAX:002
  
  DOI: 10.1016/j.jacbts.2026.101649
  
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  Curator: @sonofthor
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:002207
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pmc.ncbi.nlm.nih.gov/articles/PMC13521163/
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

STAT4‐dependent regulation of neuroinflammation in atherosclerosis

1
1. scibot 09 Apr 2026
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.14814/phy2.70856
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13053938/
Feb 2026
www.biorxiv.org www.biorxiv.org

Immunoregulatory gene GIMAP6 suppresses lethal atherosclerotic vasculopathy and ischemic heart failure

1
1. scibot 03 Feb 2026
  
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  JAX Stock No. 002207
  
  DOI: 10.64898/2026.01.26.701509
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @dhovakimyan1
  
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biorxiv.org/content/10.64898/2026.01.26.701509v1
Dec 2025
www.sciencedirect.com www.sciencedirect.com

Integrated high-throughput miRNomics and lipidomics in mice with altered lipoprotein metabolism

1
1. scibot 23 Dec 2025
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1016/j.atherosclerosis.2025.120622
  
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sciencedirect.com/science/article/pii/S0021915025015205
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lamin A/C Expression in Hematopoietic Cells Declines During Human Aging and Constrains Atherosclerosis in Mice

1
1. scibot 09 Sep 2025
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1161/ATVBAHA.124.322893
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12379799/
Aug 2025
www.biorxiv.org www.biorxiv.org

Nanoparticle-enabled plasma proteomics of a mouse atherosclerosis model

1
1. scibot 08 Aug 2025
  
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  JAX:002207
  
  DOI: 10.1101/2025.08.01.667173
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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biorxiv.org/content/10.1101/2025.08.01.667173v1
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Chalcone derivative 1m mitigates hepatic fibrosis and inflammation, enhances cholesterol efflux and reduces atherosclerosis

1
1. scibot 15 Jul 2025
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1016/j.intimp.2025.115189
  
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sciencedirect.com/science/article/pii/S1567576925011798
www.ahajournals.org www.ahajournals.org

Oxidized Phospholipid oxPAPC Alters Regulatory T-Cell Differentiation and Decreases Their Protective Function in Atherosclerosis in Mice

1
1. scibot 04 Jul 2025
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1161/ATVBAHA.123.319674
  
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ahajournals.org/doi/10.1161/ATVBAHA.123.319674
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps

1
1. scibot 02 Jul 2025
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1371/journal.ppat.1013267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12201663/
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Potentiation of macrophage Piezo1 by atherogenic 7-ketocholesterol

1
1. scibot 15 Apr 2025
  
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  The Jackson laboratoryCat#002207
  
  DOI: 10.1016/j.celrep.2025.115542
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S2211124725003134
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans-fat-induced atherosclerosis

1
1. scibot 21 Nov 2024
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1016/j.cmet.2024.10.016
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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sciencedirect.com/science/article/pii/S1550413124004121
Aug 2024
cardiab.biomedcentral.com cardiab.biomedcentral.com

Identification of regulatory networks and crosstalk factors in brown adipose tissue and liver of a cold-exposed cardiometabolic mouse model

1
1. scibot 22 Aug 2024
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1186/s12933-024-02397-7
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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cardiab.biomedcentral.com/articles/10.1186/s12933-024-02397-7
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

T cells with increased responsiveness cause obesity in mice without diet intervention

1
1. scibot 03 Apr 2024
  
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  Jackson Laboratory#002207
  
  DOI: 10.1016/j.isci.2024.109471
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10973599/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Shaping immune landscape of colorectal cancer by cholesterol metabolites

1
1. scibot 21 Mar 2024
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1038/s44321-023-00015-9
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10897227/
www.sciencedirect.com www.sciencedirect.com

Deficiency of lncRNA MERRICAL abrogates macrophage chemotaxis and diabetes-associated atherosclerosis

1
1. scibot 01 Mar 2024
  
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  Jackson002207
  
  DOI: 10.1016/j.celrep.2024.113815
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:002207
  
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sciencedirect.com/science/article/pii/S2211124724001438
Nov 2023
www.sciencedirect.com www.sciencedirect.com

An obesogenic diet increases atherosclerosis through promoting microbiota dysbiosis-induced gut lymphocyte trafficking into the periphery

1
1. scibot 02 Nov 2023
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1016/j.celrep.2023.113350
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124723013621
Sep 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Microglia contribute to cognitive decline in hypercholesterolemic LDLr−/− mice

1
1. scibot 13 Sep 2023
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1111/jnc.15952
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15952
Jul 2023
www.sciencedirect.com www.sciencedirect.com

GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis

1
1. scibot 27 Jul 2023
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1016/j.isci.2023.107293
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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sciencedirect.com/science/article/pii/S2589004223013706
May 2023
www.sciencedirect.com www.sciencedirect.com

Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity

1
1. scibot 27 May 2023
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1016/j.ccell.2023.04.016
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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sciencedirect.com/science/article/pii/S1535610823001423
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DNA methylation changes underlie the long-term association between periodontitis and atherosclerotic cardiovascular disease

1
1. scibot 09 May 2023
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.3389/fcvm.2023.1164499
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10160482/
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

1
1. scibot 01 Feb 2023
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.3389/fphys.2022.1023397
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9877335/
Dec 2022
www.nature.com www.nature.com

LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8

1
1. scibot 08 Dec 2022
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1038/s41556-022-01030-7
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @scibot
  
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nature.com/articles/s41556-022-01030-7
Nov 2022
www.sciencedirect.com www.sciencedirect.com

DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability

1
1. scibot 23 Nov 2022
  
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  JAX:002
  
  DOI: 10.1016/j.celrep.2022.111703
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:IMSR_JAX:002207
  
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  RRID:IMSR_JAX:002207 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S2211124722015777
Oct 2022
www.sciencedirect.com www.sciencedirect.com

A multienzyme S-nitrosylation cascade regulates cholesterol homeostasis

1
1. scibot 26 Oct 2022
  
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  RRID:IMSR_JAX:002
  
  DOI: 10.1016/j.celrep.2022.111538
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @a5munoz
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:002207
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sciencedirect.com/science/article/pii/S2211124722013948
www.sciencedirect.com www.sciencedirect.com

MDA-LDL vaccination induces athero-protective germinal-center-derived antibody responses

1
1. scibot 13 Oct 2022
  
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  002207
  
  DOI: 10.1016/j.celrep.2022.111468
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @a5munoz
  
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sciencedirect.com/science/article/pii/S2211124722013183
Jul 2022
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 29 Jul 2022
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1111/bph.15912
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @scibot
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15912
May 2022
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 27 May 2022
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1111/bph.15864
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @scibot
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15864
Dec 2021
cancerres.aacrjournals.org cancerres.aacrjournals.org

Oxidized Low-Density Lipoprotein Links Hypercholesterolemia and Bladder Cancer Aggressiveness by Promoting Cancer Stemness

1
1. scibot 22 Dec 2021
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1158/0008-5472.CAN-21-0646
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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cancerres.aacrjournals.org/content/81/22/5720
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Endothelial Cell CD36 Reduces Atherosclerosis and Controls Systemic Metabolism

1
1. scibot 11 Dec 2021
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.3389/fcvm.2021.768481
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8650007/
www.sciencedirect.com www.sciencedirect.com

Phospholipid nanoparticles: Therapeutic potentials against atherosclerosis via reducing cholesterol crystals and inhibiting inflammation

1
1. scibot 07 Dec 2021
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1016/j.ebiom.2021.103725
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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sciencedirect.com/science/article/pii/S2352396421005193
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Efferocytosis induces macrophage proliferation to help resolve tissue injury

1
1. scibot 16 Nov 2021
  
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  JAX:002207
  
  DOI: 10.1016/j.cmet.2021.10.015
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002207
  
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sciencedirect.com/science/article/pii/S1550413121005271
Aug 2021
www.sciencedirect.com www.sciencedirect.com

A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia

1
1. scibot 06 Aug 2021
  
  in Public
  
  JAX:002207
  
  DOI: 10.1016/j.celrep.2018.10.092
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002207
  
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sciencedirect.com/science/article/pii/S2211124718316966
Jul 2021
www.sciencedirect.com www.sciencedirect.com

GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis

1
1. scibot 29 Jul 2021
  
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  RRID: IMSR_JAX:002207
  
  DOI: 10.1016/j.cell.2019.10.034
  
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sciencedirect.com/science/article/pii/S0092867419312115
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An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis

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1. scibot 27 Jul 2021
  
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  002207
  
  DOI: 10.1016/j.immuni.2018.09.011
  
  Resource: (IMSR Cat# JAX_002207,RRID:IMSR_JAX:002207)
  
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sciencedirect.com/science/article/pii/S1074761318304266
May 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 20 May 2021
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1111/bph.15411
  
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  Curator: @scibot
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15411
Apr 2021
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Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

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1. scibot 27 Apr 2021
  
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  Cat# 002207
  
  DOI: 10.1016/j.cell.2021.01.049
  
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  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S0092867421000921
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Inactivation of Cys674 in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase

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1. scibot 02 Apr 2021
  
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  RRID:IMSR_JAX:002207
  
  DOI: 10.1111/bph.14937
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7070168/
Mar 2021
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Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury

1
1. scibot 18 Mar 2021
  
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  JAX:002207
  
  DOI: 10.1016/j.cmet.2020.01.001
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1550413120300012
Sep 2020
www.cell.com www.cell.com

Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism

1
1. scibot 03 Sep 2020
  
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  Jackson Laboratory# 002207
  
  DOI: 10.1016/j.cmet.2020.02.015
  
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cell.com/cell-metabolism/fulltext/S1550-4131(20)30074-7
Nov 2018
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Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution

1
1. scibot 05 Nov 2018
  
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  RRID:IMSR_JAX:002207
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1074761318303352
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Untitled document

1
1. scibot 05 Nov 2018
  
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  JAX:002207
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6113932/
www.cell.com www.cell.com

Untitled document

1
1. scibot 05 Nov 2018
  
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cell.com/cell-reports/abstract/S2211-1247(18)31168-9
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Untitled document

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S2211124718311689
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Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis

1
1. scibot 05 Nov 2018
  
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  002207
  
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sciencedirect.com/science/article/pii/S1550413118303802
Nov 2017
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Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages

1
1. scibot 08 Nov 2017
  
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  JAX:002207
  
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sciencedirect.com/science/article/pii/S0092867417309996
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Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

1
1. scibot 08 Nov 2017
  
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  Strain # 002207
  
  Curator: @Zeljana_Babic
  
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sciencedirect.com/science/article/pii/S0092867416312478