228 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia
    1
    1. scibot 10 Dec 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2024.115056

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    sciencedirect.com/science/article/pii/S2211124724014074
  3. www.sciencedirect.com www.sciencedirect.com
    EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function
    1
    1. scibot 06 Dec 2024
      Jackson Laboratory Stock_002216

      DOI: 10.1016/j.ccell.2024.11.006

      Resource: None

      Curator: @areedewitt04

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    sciencedirect.com/science/article/pii/S1535610824004410
  4. Nov 2024
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness
    1
    1. scibot 26 Nov 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1038/s41467-024-54344-5

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    pmc.ncbi.nlm.nih.gov/articles/PMC11585635/
  6. www.sciencedirect.com www.sciencedirect.com
    Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection
    1
    1. scibot 15 Nov 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2024.114951

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    sciencedirect.com/science/article/pii/S2211124724013020
  7. www.science.org www.science.org
    A B cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses
    1
    1. scibot 14 Nov 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1126/sciimmunol.add6608

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    science.org/doi/10.1126/sciimmunol.add6608
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI
    1
    1. scibot 08 Nov 2024
      002216

      DOI: 10.21203/rs.3.rs-3044426/v1

      Resource: (IMSR Cat# JAX_002216,RRID:IMSR_JAX:002216)

      Curator: @AleksanderDrozdz

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    pmc.ncbi.nlm.nih.gov/articles/PMC10371146/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI
    1
    1. scibot 07 Nov 2024
      002216

      DOI: 10.1038/s41536-024-00356-0

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      Curator: @AleksanderDrozdz

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    pmc.ncbi.nlm.nih.gov/articles/PMC10948859/
  10. journals.plos.org journals.plos.org
    Humoral and T-cell-mediated responses to an insect-specific flavivirus-based Zika virus vaccine candidate
    1
    1. scibot 07 Nov 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1371/journal.ppat.1012566

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    journals.plos.org/plospathogens/article
  11. Sep 2024
  12. www.sciencedirect.com www.sciencedirect.com
    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
    1
    1. scibot 18 Sep 2024
      Jackson Laboratory Stock_002216

      DOI: 10.1016/j.cmet.2017.10.006

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      Curator: @vtello

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      RRID:IMSR_JAX:002216 RRIDCUR:Unresolved
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    sciencedirect.com/science/article/pii/S1550413117306186
  13. www.sciencedirect.com www.sciencedirect.com
    Dietary fiber promotes antigen presentation on intestinal epithelial cells and development of small intestinal CD4+CD8αα+ intraepithelial T cells
    1
    1. scibot 10 Sep 2024
      002216

      DOI: 10.1016/j.mucimm.2024.08.010

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      Curator: @vtello

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    sciencedirect.com/science/article/pii/S1933021924000928
  14. www.sciencedirect.com www.sciencedirect.com
    Antibodies and complement are key drivers of thrombosis
    1
    1. scibot 04 Sep 2024
      Cat#002216

      DOI: 10.1016/j.immuni.2024.08.007

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      Curator: @vtello

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    sciencedirect.com/science/article/pii/S1074761324004060
  15. Aug 2024
  16. www.sciencedirect.com www.sciencedirect.com
    TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function
    1
    1. scibot 23 Aug 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.xcrm.2024.101696

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    sciencedirect.com/science/article/pii/S2666379124004178
  17. www.sciencedirect.com www.sciencedirect.com
    Inherent preference for polyunsaturated fatty acids instigates ferroptosis of Treg cells that aggravates high-fat-diet-related colitis
    1
    1. scibot 22 Aug 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2024.114636

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    sciencedirect.com/science/article/pii/S2211124724009860
  18. www.biorxiv.org www.biorxiv.org
    RAG suppresses group 2 innate lymphoid cells
    1
    1. scibot 16 Aug 2024
      Rag1−/−

      DOI: 10.1101/2024.04.23.590767

      Resource: (IMSR Cat# JAX_002216,RRID:IMSR_JAX:002216)

      Curator: @vtello

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    biorxiv.org/content/10.1101/2024.04.23.590767v1
  19. www.biorxiv.org www.biorxiv.org
    Αlpha-Synuclein Induced Immune Response Triggers Parkinson’s Disease-Like Symptoms
    1
    1. scibot 14 Aug 2024
      Jackson Laboratory

      DOI: 10.1101/2024.05.27.596130

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      Curator: @vtello

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    biorxiv.org/content/10.1101/2024.05.27.596130v1
  20. www.sciencedirect.com www.sciencedirect.com
    LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity
    1
    1. scibot 14 Aug 2024
      Strain #:002216

      DOI: 10.1016/j.cell.2024.07.016

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      Curator: @vtello

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    sciencedirect.com/science/article/pii/S0092867424007761
  21. Jul 2024
  22. www.sciencedirect.com www.sciencedirect.com
    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
    1
    1. scibot 18 Jul 2024
      002216

      DOI: 10.1016/j.cell.2024.06.012

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      Curator: @vtello

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    sciencedirect.com/science/article/pii/S0092867424006524
  23. www.sciencedirect.com www.sciencedirect.com
    PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies
    1
    1. scibot 17 Jul 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.xcrm.2024.101649

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    sciencedirect.com/science/article/pii/S266637912400363X
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GTP signaling links metabolism, DNA repair, and responses to genotoxic stress
    1
    1. scibot 14 Jul 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1158/2159-8290.CD-23-0437

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    ncbi.nlm.nih.gov/pmc/articles/PMC10872631/
  25. www.sciencedirect.com www.sciencedirect.com
    A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
    1
    1. scibot 12 Jul 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.cmet.2024.06.010

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    sciencedirect.com/science/article/pii/S1550413124002353
  26. Jun 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity
    1
    1. scibot 04 Jun 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2024.114289

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    ncbi.nlm.nih.gov/pmc/articles/PMC11315447/
  28. May 2024
  29. www.sciencedirect.com www.sciencedirect.com
    Intestinal CXCR6+ ILC3s migrate to the kidney and exacerbate renal fibrosis via IL-23 receptor signaling enhanced by PD-1 expression
    1
    1. scibot 30 May 2024
      JAX:002216

      DOI: 10.1016/j.immuni.2024.05.004

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    sciencedirect.com/science/article/pii/S1074761324002553
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mucosal-associated invariant T cells modulate innate immune cells and inhibit colon cancer growth
    1
    1. scibot 30 May 2024
      JAX:002216

      DOI: 10.1111/sji.13391

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    onlinelibrary.wiley.com/doi/10.1111/sji.13391
  31. www.sciencedirect.com www.sciencedirect.com
    Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity
    1
    1. scibot 23 May 2024
      002216

      DOI: 10.1016/j.celrep.2024.114261

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      Curator: @abever99

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    sciencedirect.com/science/article/pii/S2211124724005898
  32. aacrjournals.org aacrjournals.org
    One CD4+TCR and one CD8+TCR targeting autochthonous neoantigens are essential and sufficient for tumor eradication
    1
    1. scibot 23 May 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1158/1078-0432.CCR-23-2905

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    aacrjournals.org/clincancerres/article/30/8/1642/742133/One-CD4-TCR-and-One-CD8-TCR-Targeting
  33. www.sciencedirect.com www.sciencedirect.com
    ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
    1
    1. scibot 21 May 2024
      002216

      DOI: 10.1016/j.cell.2024.04.025

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    sciencedirect.com/science/article/pii/S0092867424004513
  34. www.sciencedirect.com www.sciencedirect.com
    Circadian-clock-controlled endocrine and cytokine signals regulate multipotential innate lymphoid cell progenitors in the bone marrow
    1
    1. scibot 09 May 2024
      002216

      DOI: 10.1016/j.celrep.2024.114200

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    sciencedirect.com/science/article/pii/S221112472400528X
  35. Apr 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages
    1
    1. scibot 18 Apr 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2024.03.020

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    sciencedirect.com/science/article/pii/S1074761324001419
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1
    1
    1. scibot 18 Apr 2024
      RRID:IMSR_JAX:002216

      DOI: 10.21203/rs.3.rs-3957355/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996787/
  38. www.biorxiv.org www.biorxiv.org
    PVRL2 Suppresses Anti-tumor Immunity Through PVRIG- and TIGIT-Independent Pathways
    1
    1. scibot 02 Apr 2024
      002216

      DOI: 10.1101/2024.01.26.577132

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      Curator: @bandrow

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    biorxiv.org/content/10.1101/2024.01.26.577132v1
  39. Mar 2024
  40. www.sciencedirect.com www.sciencedirect.com
    SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions
    1
    1. scibot 08 Mar 2024
      The Jackson LaboratoryStock# 002216

      DOI: 10.1016/j.ccell.2024.02.011

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    sciencedirect.com/science/article/pii/S1535610824000552
  41. www.biorxiv.org www.biorxiv.org
    The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness
    1
    1. scibot 08 Mar 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1101/2024.02.26.582122

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    biorxiv.org/content/10.1101/2024.02.26.582122v1
  42. Feb 2024
  43. www.sciencedirect.com www.sciencedirect.com
    LAG-3- and CXCR5-expressing CD4 T cells display progenitor-like properties during chronic visceral leishmaniasis
    1
    1. scibot 29 Feb 2024
      The Jackson Laboratory002216

      DOI: 10.1016/j.celrep.2024.113879

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    sciencedirect.com/science/article/pii/S2211124724002079
  44. www.sciencedirect.com www.sciencedirect.com
    Suppression of adaptive NK cell expansion by macrophage-mediated phagocytosis inhibited by 2B4-CD48
    1
    1. scibot 22 Feb 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2024.113800

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    sciencedirect.com/science/article/pii/S2211124724001281
  45. www.sciencedirect.com www.sciencedirect.com
    Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection
    1
    1. scibot 02 Feb 2024
      JAX:002216

      DOI: 10.1016/j.chom.2024.01.002

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    sciencedirect.com/science/article/pii/S1931312824000064
  46. Jan 2024
  47. www.sciencedirect.com www.sciencedirect.com
    Sensory neurons promote immune homeostasis in the lung
    1
    1. scibot 26 Jan 2024
      Rag1-/-Jackson LaboratoryStock No. 002216

      DOI: 10.1016/j.cell.2023.11.027

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    sciencedirect.com/science/article/pii/S0092867423013132
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A molecular signature for IL-10–producing Th1 cells in protozoan parasitic diseases
    1
    1. scibot 26 Jan 2024
      JAX:002216

      DOI: 10.1172/jci.insight.169362

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    ncbi.nlm.nih.gov/pmc/articles/PMC10807716/
  49. www.sciencedirect.com www.sciencedirect.com
    Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation
    1
    1. scibot 11 Jan 2024
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.chom.2023.12.006

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  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Age-associated features of norovirus infection analysed in mice
    1
    1. scibot 03 Jan 2024
      002216

      DOI: 10.1038/s41564-023-01383-1

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  51. Dec 2023
  52. www.sciencedirect.com www.sciencedirect.com
    IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis
    1
    1. scibot 02 Dec 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2023.113508

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  53. www.biorxiv.org www.biorxiv.org
    Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition
    1
    1. scibot 01 Dec 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1101/2023.11.14.567048

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  54. Nov 2023
  55. www.sciencedirect.com www.sciencedirect.com
    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
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      JAX:002216

      DOI: 10.1016/j.devcel.2023.10.010

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  56. www.sciencedirect.com www.sciencedirect.com
    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
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      DOI: 10.1016/j.immuni.2023.09.013

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  57. www.sciencedirect.com www.sciencedirect.com
    An obesogenic diet increases atherosclerosis through promoting microbiota dysbiosis-induced gut lymphocyte trafficking into the periphery
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      DOI: 10.1016/j.celrep.2023.113350

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  58. Oct 2023
  59. www.biorxiv.org www.biorxiv.org
    CCR5 promotes the migration of CD8+ T cells to the leishmanial lesions
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      RRID:IMSR_JAX:002216

      DOI: 10.1101/2023.10.10.561700

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  60. www.sciencedirect.com www.sciencedirect.com
    Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1
    1
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      DOI: 10.1016/j.cmet.2023.09.004

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  61. Sep 2023
  62. dx.doi.org dx.doi.org
    Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma
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      RRID:IMSR_JAX:002216

      DOI: 10.1158/0008-5472.CAN-22-3114

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    dx.doi.org/10.1158/0008-5472.CAN-22-3114
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex-Biased T-cell Exhaustion Drives Differential Immune Responses in Glioblastoma
    1
    1. scibot 09 Sep 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1158/2159-8290.CD-22-0869

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  64. Aug 2023
  65. www.biorxiv.org www.biorxiv.org
    Overcome Prostate Cancer Resistance to Immune Checkpoint Therapy with Ketogenic Diet-Induced Epigenetic Reprogramming
    1
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      RRID:IMSR_JAX:002216

      DOI: 10.1101/2023.08.07.552383

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  66. www.sciencedirect.com www.sciencedirect.com
    Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection
    1
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      JAX:002216

      DOI: 10.1016/j.immuni.2023.07.014

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  67. Jul 2023
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of B cells in immune cell activation in polycystic ovary syndrome
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      JAX:002216

      DOI: 10.7554/eLife.86454

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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E protein binding at the Tcra enhancer promotes Tcra repertoire diversity
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      JAX:002216

      DOI: 10.3389/fimmu.2023.1188738

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  70. www.sciencedirect.com www.sciencedirect.com
    Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells
    1
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      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2023.112839

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Siglec-15 promotes evasion of adaptive immunity in B-cell acute lymphoblastic leukemia
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      RRID:IMSR_JAX:002216

      DOI: 10.1158/2767-9764.CRC-23-0056

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  72. www.sciencedirect.com www.sciencedirect.com
    A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity
    1
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      JAX:002216

      DOI: 10.1016/j.ccell.2023.06.008

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  73. 52.53.155.43 52.53.155.43
    crc-23-0056-html.html
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      RRID:IMSR_JAX:002216

      DOI: 10.1158/2767-9764.crc-23-0056

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  74. www.sciencedirect.com www.sciencedirect.com
    Kidney capsule transplantation of chemically treated embryonic murine tooth germs
    1
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      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.xpro.2023.102377

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  75. www.sciencedirect.com www.sciencedirect.com
    Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways
    1
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      RRID:IMSR_JAX:002216

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    sciencedirect.com/science/article/pii/S2211124723007167
  76. Jun 2023
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen
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      RRID:IMSR_JAX:002216

      DOI: 10.1126/sciadv.adg8719

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  78. www.sciencedirect.com www.sciencedirect.com
    Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
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      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2023.05.004

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    sciencedirect.com/science/article/pii/S1074761323002212
  79. May 2023
  80. www.sciencedirect.com www.sciencedirect.com
    Proteomics of immune cells from liver tumors reveals immunotherapy targets
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      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.xgen.2023.100331

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    sciencedirect.com/science/article/pii/S2666979X2300099X
  81. www.embopress.org www.embopress.org
    Bacteria-instructed B cells cross-prime naïve CD8+ T cells triggering effective cytotoxic responses
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      RRID:IMSR_JAX:002216

      DOI: 10.15252/embr.202256131

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  82. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic CNS-associated T cells drive axon degeneration by targeting perturbed oligodendrocytes in PLP1 mutant mice
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    1. scibot 14 May 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.isci.2023.106698

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  83. www.sciencedirect.com www.sciencedirect.com
    Recruitment of epitope-specific T cell clones with a low-avidity threshold supports efficacy against mutational escape upon re-infection
    1
    1. scibot 10 May 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2023.04.010

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    sciencedirect.com/science/article/pii/S1074761323001796
  84. Apr 2023
  85. www.biorxiv.org www.biorxiv.org
    GTP signaling links metabolism, DNA repair, and responses to genotoxic stress
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      RRID:IMSR_JAX:002216

      DOI: 10.1101/2023.04.12.536297

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    biorxiv.org/content/10.1101/2023.04.12.536297v1
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory
    1
    1. scibot 05 Apr 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1126/sciimmunol.abq7432

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    ncbi.nlm.nih.gov/pmc/articles/PMC9835709/
  87. Mar 2023
  88. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    STING agonist-loaded, CD47/PD-L1-targeting nanoparticles potentiate antitumor immunity and radiotherapy for glioblastoma
    1
    1. scibot 28 Mar 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1038/s41467-023-37328-9

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    pubmed.ncbi.nlm.nih.gov/36959214/
  89. europepmc.org europepmc.org
    Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING
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    1. scibot 28 Mar 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2023.112303

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  90. www.sciencedirect.com www.sciencedirect.com
    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
    1
    1. scibot 23 Mar 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.molcel.2023.02.026

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  91. europepmc.org europepmc.org
    ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery
    1
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      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2023.112269

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    europepmc.org/article/med/36933213
  92. Feb 2023
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen
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    1. scibot 11 Feb 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1101/2023.01.22.525099

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  94. www.sciencedirect.com www.sciencedirect.com
    Ambient oxygen levels regulate intestinal dysbiosis and GVHD severity after allogeneic stem cell transplantation
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      DOI: 10.1016/j.immuni.2023.01.007

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  95. Jan 2023
  96. www.sciencedirect.com www.sciencedirect.com
    Dopamine inhibits group 2 innate lymphoid cell-driven allergic lung inflammation by dampening mitochondrial activity
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    1. scibot 24 Jan 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2022.12.017

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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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      DOI: 10.1158/0008-5472.CAN-21-3217

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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
  98. www.sciencedirect.com www.sciencedirect.com
    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
    1
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      JAX:002

      DOI: 10.1016/j.immuni.2022.12.010

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      Curator: @a5munoz

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    sciencedirect.com/science/article/pii/S107476132200646X
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 haploinsufficiency enhances germinal center-associated AICDA somatic hypermutation to drive B cell lymphomagenesis
    1
    1. scibot 07 Jan 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1158/2159-8290.CD-21-1514

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    ncbi.nlm.nih.gov/pmc/articles/PMC9262862/
  100. www.sciencedirect.com www.sciencedirect.com
    Immunoediting instructs tumor metabolic reprogramming to support immune evasion
    1
    1. scibot 04 Jan 2023
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.cmet.2022.12.003

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    sciencedirect.com/science/article/pii/S155041312200540X
  101. Dec 2022
  102. www.mdpi.com www.mdpi.com
    Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice
    1
    1. scibot 22 Dec 2022
      RRID:IMSR_JAX:002216

      DOI: 10.3390/cells11244116

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    mdpi.com/2073-4409/11/24/4116
  103. Nov 2022
  104. www.sciencedirect.com www.sciencedirect.com
    Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity
    1
    1. scibot 10 Nov 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2022.111593

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    sciencedirect.com/science/article/pii/S2211124722014589
  105. www.sciencedirect.com www.sciencedirect.com
    Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy
    1
    1. scibot 03 Nov 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2022.111582

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    sciencedirect.com/science/article/pii/S2211124722014474
  106. Oct 2022
  107. www.sciencedirect.com www.sciencedirect.com
    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
    1
    1. scibot 20 Oct 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2022.09.014

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    sciencedirect.com/science/article/pii/S1074761322005088
  108. www.sciencedirect.com www.sciencedirect.com
    Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element
    1
    1. scibot 18 Oct 2022
      JAX:002216

      DOI: 10.1016/j.immuni.2022.09.013

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    sciencedirect.com/science/article/pii/S1074761322005076
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages
    1
    1. scibot 04 Oct 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.isci.2022.105151

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    ncbi.nlm.nih.gov/pmc/articles/PMC9523381/
  110. Sep 2022
  111. www.sciencedirect.com www.sciencedirect.com
    Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation
    1
    1. scibot 15 Sep 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2022.111345

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    sciencedirect.com/science/article/pii/S2211124722011731
  112. www.sciencedirect.com www.sciencedirect.com
    ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes
    1
    1. scibot 08 Sep 2022
      Mouse: Rag1−/− C57BL/6J

      DOI: 10.1016/j.cmet.2022.08.007

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    sciencedirect.com/science/article/pii/S1550413122003503
  113. Jun 2022
  114. 52.53.155.43 52.53.155.43
    cd-21-1514-html.html
    3
    1. scibot 30 Jun 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1158/2159-8290.CD-21-1514

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    2. scibot 25 Jun 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1158/2159-8290.cd-21-1514

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      RRID:IMSR_JAX:002216
    3. scibot 23 Jun 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1158/2159-8290.cd-21-1514

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    52.53.155.43/30b9574de57b2e4ccfd380c8f4f8e4cb5eb75f43/cd-21-1514-html.html
  115. www.sciencedirect.com www.sciencedirect.com
    Robust anti-SARS-CoV2 single domain antibodies cross neutralize multiple viruses
    1
    1. scibot 24 Jun 2022
      Jackson laboratory, USA002216

      DOI: 10.1016/j.isci.2022.104549

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    sciencedirect.com/science/article/pii/S2589004222008215
  116. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
    2
    1. scibot 24 Jun 2022
      Jackson LabsCat# 002216

      DOI: 10.1016/j.ccell.2022.06.001

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      RRID:IMSR_JAX:002216
    2. scibot 24 Jun 2022
      JAX:002216

      DOI: 10.1016/j.ccell.2022.06.001

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    sciencedirect.com/science/article/pii/S1535610822002318
  117. www.sciencedirect.com www.sciencedirect.com
    Langerhans cells are an essential cellular intermediary in chronic dermatitis
    1
    1. scibot 09 Jun 2022
      JAX:002216

      DOI: 10.1016/j.celrep.2022.110922

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    sciencedirect.com/science/article/pii/S2211124722006994
  118. www.sciencedirect.com www.sciencedirect.com
    Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer
    1
    1. scibot 03 Jun 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.ccell.2022.05.006

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    sciencedirect.com/science/article/pii/S1535610822002173
  119. aacrjournals.org aacrjournals.org
    Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function
    1
    1. scibot 01 Jun 2022
      Jackson Laboratory Stock# 002216

      DOI: 10.1158/0008-5472.CAN-21-3155

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    aacrjournals.org/cancerres/article/82/10/1969/696318/Carbon-Monoxide-Activates-PERK-Regulated-Autophagy
  120. May 2022
  121. www.sciencedirect.com www.sciencedirect.com
    Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer
    1
    1. scibot 27 May 2022
      The Jackson LaboratoryStock # 002216

      DOI: 10.1016/j.ccell.2022.05.004

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    sciencedirect.com/science/article/pii/S153561082200215X
  122. Apr 2022
  123. www.sciencedirect.com www.sciencedirect.com
    Progenitor potential of lung epithelial organoid cells in a transplantation model
    1
    1. scibot 14 Apr 2022
      The Jackson LaboratoryCat# 02216

      DOI: 10.1016/j.celrep.2022.110662

      Resource: (IMSR Cat# JAX_002216,RRID:IMSR_JAX:002216)

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    sciencedirect.com/science/article/pii/S2211124722004144
  124. aacrjournals.org aacrjournals.org
    mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment
    2
    1. scibot 07 Apr 2022
      JAX:002216

      DOI: 10.1158/1541-7786.MCR-20-0799

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    2. scibot 07 Apr 2022
      RRID:IMSR_JAX

      DOI: 10.1158/1541-7786.MCR-20-0799

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      Curator: @evieth

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      RRIDCUR:Unresolved RRID:IMSR_JAX:002216
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    aacrjournals.org/mcr/article/19/4/717/672854/mDKN-01-a-Novel-Anti-DKK1-mAb-Enhances-Innate
  125. www.sciencedirect.com www.sciencedirect.com
    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
    1
    1. scibot 01 Apr 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2022.03.008

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    sciencedirect.com/science/article/pii/S1074761322001315
  126. Mar 2022
  127. www.sciencedirect.com www.sciencedirect.com
    Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection
    1
    1. scibot 30 Mar 2022
      Jackson Laboratory StockCat# 002216

      DOI: 10.1016/j.celrep.2022.110560

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    sciencedirect.com/science/article/pii/S2211124722003047
  128. www.sciencedirect.com www.sciencedirect.com
    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
    1
    1. scibot 18 Mar 2022
      Jackson LaboratoryCat# 002216

      DOI: 10.1016/j.xcrm.2022.100554

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    sciencedirect.com/science/article/pii/S266637912200060X
  129. www.sciencedirect.com www.sciencedirect.com
    Setd2 determines distinct properties of intestinal ILC3 subsets to regulate intestinal immunity
    1
    1. scibot 18 Mar 2022
      Jackson LaboratoriesCat#002216

      DOI: 10.1016/j.celrep.2022.110530

      Resource: (IMSR Cat# JAX_002216,RRID:IMSR_JAX:002216)

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    sciencedirect.com/science/article/pii/S2211124722002716
  130. www.sciencedirect.com www.sciencedirect.com
    RORγt phosphorylation protects against T cell-mediated inflammation
    1
    1. scibot 16 Mar 2022
      The Jackson LaboratoryStrain #002216

      DOI: 10.1016/j.celrep.2022.110520

      Resource: (IMSR Cat# JAX_002216,RRID:IMSR_JAX:002216)

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    sciencedirect.com/science/article/pii/S221112472200256X
  131. www.sciencedirect.com www.sciencedirect.com
    Tumor-derived Jagged1 promotes cancer progression through immune evasion
    1
    1. scibot 09 Mar 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2022.110492

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    sciencedirect.com/science/article/pii/S221112472200225X
  132. www.sciencedirect.com www.sciencedirect.com
    A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts
    1
    1. scibot 09 Mar 2022
      JAX:002216

      DOI: 10.1016/j.immuni.2022.02.003

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    sciencedirect.com/science/article/pii/S1074761322000838
  133. Feb 2022
  134. www.sciencedirect.com www.sciencedirect.com
    Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity
    1
    1. scibot 18 Feb 2022
      The Jackson LaboratoryJAX# 002216

      DOI: 10.1016/j.cell.2022.01.017

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    sciencedirect.com/science/article/pii/S0092867422000757
  135. www.sciencedirect.com www.sciencedirect.com
    Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination
    1
    1. scibot 16 Feb 2022
      The Jackson Laboratory002216

      DOI: 10.1016/j.celrep.2022.110388

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    sciencedirect.com/science/article/pii/S2211124722001097
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC and MIZ1-dependent vesicular transport of double-strand RNA controls immune evasion in pancreatic ductal adenocarcinoma
    1
    1. scibot 16 Feb 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1158/0008-5472.CAN-21-1677

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    ncbi.nlm.nih.gov/pmc/articles/PMC7611539/
  137. www.sciencedirect.com www.sciencedirect.com
    Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation
    2
    1. scibot 11 Feb 2022
      002216

      DOI: 10.1016/j.immuni.2022.01.011

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    2. scibot 11 Feb 2022
      002216

      DOI: 10.1016/j.immuni.2022.01.011

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    sciencedirect.com/science/article/pii/S1074761322000401
  138. Jan 2022
  139. www.sciencedirect.com www.sciencedirect.com
    Regulation of the BCR signalosome by the class II peptide editor, H2-M, affects the development and repertoire of innate-like B cells
    1
    1. scibot 26 Jan 2022
      The Jackson Lab002216

      DOI: 10.1016/j.celrep.2021.110200

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    sciencedirect.com/science/article/pii/S2211124721017046
  140. www.sciencedirect.com www.sciencedirect.com
    TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures
    1
    1. scibot 12 Jan 2022
      The Jackson LaboratoryStrain: 002216

      DOI: 10.1016/j.immuni.2021.12.007

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    sciencedirect.com/science/article/pii/S1074761321005434
  141. www.sciencedirect.com www.sciencedirect.com
    Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections
    1
    1. scibot 05 Jan 2022
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2021.110184

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    sciencedirect.com/science/article/pii/S2211124721016843
  142. Dec 2021
  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice
    1
    1. scibot 11 Dec 2021
      RRID:IMSR_JAX:002216

      DOI: 10.7554/eLife.69056

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    ncbi.nlm.nih.gov/pmc/articles/PMC8639143/
  144. www.sciencedirect.com www.sciencedirect.com
    NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
    1
    1. scibot 08 Dec 2021
      002216

      DOI: 10.1016/j.cmet.2021.11.011

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    sciencedirect.com/science/article/pii/S1550413121005398
  145. www.sciencedirect.com www.sciencedirect.com
    Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells
    1
    1. scibot 08 Dec 2021
      Cat# 002216

      DOI: 10.1016/j.immuni.2021.11.005

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    sciencedirect.com/science/article/pii/S1074761321004969
  146. www.sciencedirect.com www.sciencedirect.com
    Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis
    1
    1. scibot 08 Dec 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2021.110099

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    sciencedirect.com/science/article/pii/S221112472101593X
  147. Nov 2021
  148. www.sciencedirect.com www.sciencedirect.com
    Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor
    1
    1. scibot 17 Nov 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2021.10.003

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    sciencedirect.com/science/article/pii/S107476132100409X
  149. www.sciencedirect.com www.sciencedirect.com
    MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function
    1
    1. scibot 12 Nov 2021
      JAX:002216

      DOI: 10.1016/j.immuni.2021.10.011

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    sciencedirect.com/science/article/pii/S1074761321004489
  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function
    1
    1. scibot 05 Nov 2021
      The Jackson LaboratoryStock No: 002216

      DOI: 10.7554/eLife.67476

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    ncbi.nlm.nih.gov/pmc/articles/PMC8553335/
  151. Oct 2021
  152. www.sciencedirect.com www.sciencedirect.com
    Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells
    1
    1. scibot 23 Oct 2021
      Stock Number #002216

      DOI: 10.1016/j.immuni.2021.09.021

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    sciencedirect.com/science/article/pii/S1074761321004064
  153. Sep 2021
  154. www.sciencedirect.com www.sciencedirect.com
    Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma
    1
    1. scibot 15 Sep 2021
      JAX:002216

      DOI: 10.1016/j.xcrm.2021.100399

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    sciencedirect.com/science/article/pii/S2666379121002573
  155. www.sciencedirect.com www.sciencedirect.com
    Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity
    1
    1. scibot 04 Sep 2021
      Cat#002216

      DOI: 10.1016/j.immuni.2021.08.005

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    sciencedirect.com/science/article/pii/S1074761321003356
  156. Aug 2021
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 13 Aug 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2019.03.029

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    ncbi.nlm.nih.gov/pmc/articles/PMC6461402/
  158. www.sciencedirect.com www.sciencedirect.com
    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
    1
    1. scibot 08 Aug 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2017.11.003

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    sciencedirect.com/science/article/pii/S1074761317304806
  159. www.sciencedirect.com www.sciencedirect.com
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    1
    1. scibot 01 Aug 2021
      JAX:002216

      DOI: 10.1016/j.immuni.2018.10.012

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    sciencedirect.com/science/article/pii/S1074761318304771
  160. www.sciencedirect.com www.sciencedirect.com
    LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer
    1
    1. scibot 01 Aug 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.cell.2017.12.026

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    sciencedirect.com/science/article/pii/S0092867417315064
  161. www.sciencedirect.com www.sciencedirect.com
    High Glucose Intake Exacerbates Autoimmunity through Reactive-Oxygen-Species-Mediated TGF-β Cytokine Activation
    1
    1. scibot 01 Aug 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2019.08.001

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    sciencedirect.com/science/article/pii/S1074761319303279
  162. www.cell.com www.cell.com
    Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells
    1
    1. scibot 01 Aug 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.cmet.2019.05.016

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    cell.com/cell-metabolism/fulltext/S1550-4131(19)30256-6
  163. Jul 2021
  164. www.sciencedirect.com www.sciencedirect.com
    The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock
    1
    1. scibot 31 Jul 2021
      Cat# 002216

      DOI: 10.1016/j.cell.2021.07.001

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    sciencedirect.com/science/article/pii/S0092867421008278
  165. www.cell.com www.cell.com
    Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection
    1
    1. scibot 31 Jul 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2019.03.059

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    cell.com/cell-reports/fulltext/S2211-1247(19)30389-4
  166. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 31 Jul 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.cmet.2019.01.019

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    sciencedirect.com/science/article/pii/S1550413119300191
  167. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 31 Jul 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.cels.2019.01.004

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    sciencedirect.com/science/article/pii/S2405471219300328
  168. www.sciencedirect.com www.sciencedirect.com
    Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses
    1
    1. scibot 30 Jul 2021
      RRID: IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2019.11.070

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    sciencedirect.com/science/article/pii/S221112471931561X
  169. www.sciencedirect.com www.sciencedirect.com
    Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
    1
    1. scibot 30 Jul 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.cell.2018.10.001

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    sciencedirect.com/science/article/pii/S0092867418313096
  170. www.sciencedirect.com www.sciencedirect.com
    Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity
    1
    1. scibot 30 Jul 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.cell.2018.09.042

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    sciencedirect.com/science/article/pii/S0092867418312546
  171. www.sciencedirect.com www.sciencedirect.com
    Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence
    1
    1. scibot 30 Jul 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.devcel.2018.10.001

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    sciencedirect.com/science/article/pii/S1534580718308220
  172. www.sciencedirect.com www.sciencedirect.com
    Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity
    1
    1. scibot 29 Jul 2021
      Jackson LaboratoryStock#002216

      DOI: 10.1016/j.celrep.2019.07.065

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    sciencedirect.com/science/article/pii/S2211124719309696
  173. www.sciencedirect.com www.sciencedirect.com
    Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation
    1
    1. scibot 29 Jul 2021
      The Jackson Laboratory#002216

      DOI: 10.1016/j.immuni.2019.06.009

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    sciencedirect.com/science/article/pii/S1074761319302791
  174. www.sciencedirect.com www.sciencedirect.com
    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
    1
    1. scibot 29 Jul 2021
      B6.129S7-Rag1tm1Mom/J

      DOI: 10.1016/j.celrep.2019.07.044

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    sciencedirect.com/science/article/pii/S2211124719309416
  175. www.sciencedirect.com www.sciencedirect.com
    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
    1
    1. scibot 28 Jul 2021
      B6.129S7-Rag1tm1Mom/J

      DOI: 10.1016/j.celrep.2019.05.020

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    sciencedirect.com/science/article/pii/S221112471930631X
  176. www.sciencedirect.com www.sciencedirect.com
    A Single-Cell Transcriptomic Atlas of Thymus Organogenesis Resolves Cell Types and Developmental Maturation
    1
    1. scibot 28 Jul 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2018.04.015

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    sciencedirect.com/science/article/pii/S1074761318301845
  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ORAI2 modulates store-operated calcium entry and T cell-mediated immunity
    1
    1. scibot 27 Jul 2021
      002216

      DOI: 10.1038/ncomms14714

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    ncbi.nlm.nih.gov/pmc/articles/PMC5355949/
  178. www.sciencedirect.com www.sciencedirect.com
    Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis
    1
    1. scibot 27 Jul 2021
      002216

      DOI: 10.1016/j.cmet.2018.10.006

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    sciencedirect.com/science/article/pii/S1550413118306387
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses
    1
    1. scibot 27 Jul 2021
      C57BL/6J 129S7-Rag1tm1Mom/J (Rag1 u2212/u2212) mice

      DOI: 10.1038/s41467-017-01661-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC5691066/
  180. www.sciencedirect.com www.sciencedirect.com
    IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice
    1
    1. scibot 21 Jul 2021
      JAX:002216

      DOI: 10.1016/j.neuron.2021.06.015

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    sciencedirect.com/science/article/pii/S0896627321004566
  181. www.sciencedirect.com www.sciencedirect.com
    Cell-intrinsic glial pathology is conserved across human and murine models of Huntington’s disease
    1
    1. scibot 10 Jul 2021
      Cat#002216

      DOI: 10.1016/j.celrep.2021.109308

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    sciencedirect.com/science/article/pii/S2211124721006847
  182. www.sciencedirect.com www.sciencedirect.com
    Splicing factor SRSF1 is indispensable for regulatory T cell homeostasis and function
    1
    1. scibot 09 Jul 2021
      stock 002216

      DOI: 10.1016/j.celrep.2021.109339

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    sciencedirect.com/science/article/pii/S2211124721007154
  183. www.sciencedirect.com www.sciencedirect.com
    Commensal microbiota regulates skin barrier function and repair via signaling through the aryl hydrocarbon receptor
    1
    1. scibot 03 Jul 2021
      stock#002216

      DOI: 10.1016/j.chom.2021.05.011

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    sciencedirect.com/science/article/pii/S1931312821002390
  184. www.sciencedirect.com www.sciencedirect.com
    Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy
    1
    1. scibot 03 Jul 2021
      002216

      DOI: 10.1016/j.cell.2021.06.004

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    sciencedirect.com/science/article/pii/S0092867421007054
  185. Jun 2021
  186. www.sciencedirect.com www.sciencedirect.com
    Toll-like receptor 2 induces pathogenicity in Th17 cells and reveals a role for IPCEF in regulating Th17 cell migration
    1
    1. scibot 30 Jun 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2021.109303

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    sciencedirect.com/science/article/pii/S2211124721006793
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells
    1
    1. scibot 17 Jun 2021
      JAX:002216

      DOI: 10.1371/journal.ppat.1009593

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    ncbi.nlm.nih.gov/pmc/articles/PMC8172060/
  188. May 2021
  189. www.sciencedirect.com www.sciencedirect.com
    NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes
    1
    1. scibot 26 May 2021
      JAX:002216

      DOI: 10.1016/j.celrep.2021.109176

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    sciencedirect.com/science/article/pii/S2211124721005210
  190. www.sciencedirect.com www.sciencedirect.com
    Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke
    1
    1. scibot 20 May 2021
      Stock No: 002216

      DOI: 10.1016/j.immuni.2021.04.022

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    sciencedirect.com/science/article/pii/S1074761321001849
  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T cell self-reactivity during thymic development dictates the timing of positive selection
    1
    1. scibot 19 May 2021
      RRID:IMSR_JAX:002216

      DOI: 10.7554/eLife.65435

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    ncbi.nlm.nih.gov/pmc/articles/PMC8116051/
  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii
    1
    1. scibot 19 May 2021
      RRID:IMSR_JAX:002216

      DOI: 10.7554/eLife.65614

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    ncbi.nlm.nih.gov/pmc/articles/PMC8121546/
  193. www.sciencedirect.com www.sciencedirect.com
    T Cell Receptor Is Required for Differentiation, but Not Maintenance, of Intestinal CD4+ Intraepithelial Lymphocytes
    1
    1. scibot 15 May 2021
      Jax: 002216

      DOI: 10.1016/j.immuni.2020.09.003

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    sciencedirect.com/science/article/pii/S1074761320303976
  194. www.sciencedirect.com www.sciencedirect.com
    Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis
    1
    1. scibot 15 May 2021
      Cat# 002216

      DOI: 10.1016/j.immuni.2020.04.010

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    sciencedirect.com/science/article/pii/S1074761320301680
  195. www.sciencedirect.com www.sciencedirect.com
    Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23
    1
    1. scibot 14 May 2021
      Jax: 002216

      DOI: 10.1016/j.cmet.2021.04.015

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    sciencedirect.com/science/article/pii/S1550413121001819
  196. www.sciencedirect.com www.sciencedirect.com
    Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice
    1
    1. scibot 09 May 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1053/j.gastro.2020.11.044

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    sciencedirect.com/science/article/pii/S001650852035513X
  197. www.sciencedirect.com www.sciencedirect.com
    Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues
    1
    1. scibot 07 May 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2020.10.012

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    sciencedirect.com/science/article/pii/S1074761320304532
  198. www.sciencedirect.com www.sciencedirect.com
    Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche
    1
    1. scibot 07 May 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2020.10.022

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    sciencedirect.com/science/article/pii/S1074761320304635
  199. Apr 2021
  200. www.sciencedirect.com www.sciencedirect.com
    Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells
    1
    1. scibot 30 Apr 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.cmet.2020.10.022

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    sciencedirect.com/science/article/pii/S155041312030591X
  201. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
    1
    1. scibot 29 Apr 2021
      002216

      DOI: 10.1016/j.cmet.2020.10.017

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    sciencedirect.com/science/article/pii/S1550413120305507
  202. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity
    1
    1. scibot 29 Apr 2021
      #002216

      DOI: 10.1016/j.cmet.2020.07.001

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    sciencedirect.com/science/article/pii/S1550413120303594
  203. www.sciencedirect.com www.sciencedirect.com
    Diet Diurnally Regulates Small Intestinal Microbiome-Epithelial-Immune Homeostasis and Enteritis
    1
    1. scibot 24 Apr 2021
      Stock No: 002216

      DOI: 10.1016/j.cell.2020.08.027

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    sciencedirect.com/science/article/pii/S0092867420310692
  204. www.sciencedirect.com www.sciencedirect.com
    Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome
    1
    1. scibot 24 Apr 2021
      002216

      DOI: 10.1016/j.chom.2021.03.015

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    sciencedirect.com/science/article/pii/S1931312821001438
  205. www.sciencedirect.com www.sciencedirect.com
    Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy
    1
    1. scibot 24 Apr 2021
      JAX:002216

      DOI: 10.1016/j.cell.2020.06.014

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    sciencedirect.com/science/article/pii/S0092867420307455
  206. www.sciencedirect.com www.sciencedirect.com
    Microbiota regulate innate immune signaling and protective immunity against cancer
    1
    1. scibot 24 Apr 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.chom.2021.03.016

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    sciencedirect.com/science/article/pii/S193131282100144X
  207. www.sciencedirect.com www.sciencedirect.com
    The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis
    1
    1. scibot 23 Apr 2021
      JAX 002216

      DOI: 10.1016/j.cell.2020.05.048

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    sciencedirect.com/science/article/pii/S0092867420306814
  208. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions
    1
    1. scibot 11 Apr 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.cell.2021.02.021

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    sciencedirect.com/science/article/pii/S0092867421001719
  209. Feb 2021
  210. www.sciencedirect.com www.sciencedirect.com
    Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
    1
    1. scibot 26 Feb 2021
      JAX:002216

      DOI: 10.1016/j.cell.2021.02.002

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    sciencedirect.com/science/article/pii/S0092867421001525
  211. Jan 2021
  212. www.sciencedirect.com www.sciencedirect.com
    Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells
    1
    1. scibot 28 Jan 2021
      Cat# 002216

      DOI: 10.1016/j.celrep.2020.108677

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    sciencedirect.com/science/article/pii/S2211124720316661
  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryptococcus neoformans Evades Pulmonary Immunity by Modulating Xylose Precursor Transport
    1
    1. scibot 26 Jan 2021
      RRID:IMSR_JAX:002216

      DOI: 10.1128/IAI.00288-20

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    ncbi.nlm.nih.gov/pmc/articles/PMC7375766/
  214. www.sciencedirect.com www.sciencedirect.com
    Foxo3 Promotes the Differentiation and Function of Follicular Helper T Cells
    1
    1. scibot 16 Jan 2021
      JAX:002216

      DOI: 10.1016/j.celrep.2020.107621

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    sciencedirect.com/science/article/pii/S221112472030574X
  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity
    1
    1. scibot 07 Jan 2021
      Stock No:002216

      DOI: 10.1016/j.celrep.2020.108601

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    ncbi.nlm.nih.gov/pmc/articles/PMC7839063/
  216. Dec 2020
  217. www.sciencedirect.com www.sciencedirect.com
    Lactate Limits T Cell Proliferation via the NAD(H) Redox State
    1
    1. scibot 17 Dec 2020
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2020.108500

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    sciencedirect.com/science/article/pii/S2211124720314893
  218. Nov 2020
  219. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Airway Microbiota-Host Interactions Regulate Secretory Leukocyte Protease Inhibitor Levels and Influence Allergic Airway Inflammation
    1
    1. scibot 07 Nov 2020
      RAG1−/− C57BL/6J: B6.129S7-Rag1tm1Mom/J

      DOI: 10.1016/j.celrep.2020.108331

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    pubmed.ncbi.nlm.nih.gov/33147448/
  220. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity
    1
    1. scibot 03 Nov 2020
      B6.129S7-Rag1tm1Mom/J

      DOI: 10.1016/j.cell.2020.09.058

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    pubmed.ncbi.nlm.nih.gov/33125892/
  221. Oct 2020
  222. www.sciencedirect.com www.sciencedirect.com
    In Vitro Recapitulation of Murine Thymopoiesis from Single Hematopoietic Stem Cells
    1
    1. scibot 31 Oct 2020
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2020.108320

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    sciencedirect.com/science/article/pii/S2211124720313097
  223. journals.plos.org journals.plos.org
    IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection
    1
    1. scibot 17 Oct 2020
      RRID:IMSR_JAX:002216

      DOI: 10.1371/journal.ppat.1008994

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    journals.plos.org/plospathogens/article
  224. www.sciencedirect.com www.sciencedirect.com
    In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors
    1
    1. scibot 01 Oct 2020
      RAG1−/−

      DOI: 10.1016/j.immuni.2020.09.002

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    sciencedirect.com/science/article/pii/S1074761320303964
  225. Sep 2020
  226. www.sciencedirect.com www.sciencedirect.com
    Control of Viral Infection by Natural Killer Cell Inhibitory Receptors
    1
    1. scibot 26 Sep 2020
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2020.107969

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    sciencedirect.com/science/article/pii/S2211124720309505
  227. www.sciencedirect.com www.sciencedirect.com
    Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation
    1
    1. scibot 26 Sep 2020
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2020.107892

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    sciencedirect.com/science/article/pii/S2211124720308731
  228. www.sciencedirect.com www.sciencedirect.com
    Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation
    1
    1. scibot 17 Sep 2020
      JAX:002216

      DOI: 10.1016/j.celrep.2020.107819

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    sciencedirect.com/science/article/pii/S2211124720308007
  229. www.nature.com www.nature.com
    The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation
    1
    1. scibot 14 Sep 2020
      RRID:IMSR_JAX:002216

      DOI: 10.1038/s41590-020-0758-6

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    nature.com/articles/s41590-020-0758-6
  230. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Host sirtuin 2 as an immunotherapeutic target against tuberculosis
    1
    1. scibot 14 Sep 2020
      RRID:IMSR_JAX:002216

      DOI: 10.7554/eLife.55415

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    ncbi.nlm.nih.gov/pmc/articles/PMC7398663/
  231. www.sciencedirect.com www.sciencedirect.com
    Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis
    1
    1. scibot 14 Sep 2020
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.celrep.2020.01.099

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    sciencedirect.com/science/article/pii/S2211124720301339
  232. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Modeling Human‐specific Interlaminar Astrocytes in the Mouse Cerebral Cortex
    1
    1. scibot 11 Sep 2020
      JAX:002216

      DOI: 10.1002/cne.24979

      Resource: (IMSR Cat# JAX_002216,RRID:IMSR_JAX:002216)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:IMSR_JAX:002216
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    onlinelibrary.wiley.com/doi/10.1002/cne.24979
  233. www.sciencedirect.com www.sciencedirect.com
    Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch
    1
    1. scibot 04 Sep 2020
      Jackson LabsStrain Code: 002216

      DOI: 10.1016/j.celrep.2020.03.036

      Resource: (IMSR Cat# JAX_002216,RRID:IMSR_JAX:002216)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:002216
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    sciencedirect.com/science/article/pii/S2211124720303508
  234. www.sciencedirect.com www.sciencedirect.com
    PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells
    1
    1. scibot 04 Sep 2020
      B6.129S7-RAG1tm1Mom/J (Rag1-/-)

      DOI: 10.1016/j.ccell.2018.06.007

      Resource: (IMSR Cat# JAX_002216,RRID:IMSR_JAX:002216)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:002216

      Curator comments: B6.129S7-Rag1tm1Mom/J Mus musculus IMSR Cat# JAX:002216

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      RRIDCUR:Missing RRID:IMSR_JAX:002216
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    sciencedirect.com/science/article/pii/S1535610818302642
  235. www.sciencedirect.com www.sciencedirect.com
    STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice
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    1. scibot 04 Sep 2020
      Jackson LaboratoryStock# 002216

      DOI: 10.1016/j.celrep.2020.107771

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      Curator: @ethanbadger

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      RRIDCUR:Missing RRID:IMSR_JAX:002216
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    sciencedirect.com/science/article/pii/S2211124720307518
  236. www.cell.com www.cell.com
    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction
    1
    1. scibot 04 Sep 2020
      RRID:IMSR_JAX:002216

      DOI: 10.1016/j.immuni.2017.11.003

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      Curator: @evieth

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    cell.com/immunity/abstract/S1074-7613(17)30480-6
  237. www.sciencedirect.com www.sciencedirect.com
    Human Glial Progenitor Cells Effectively Remyelinate the Demyelinated Adult Brain
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    1. scibot 03 Sep 2020
      Jackson LabsCat#002216

      DOI: 10.1016/j.celrep.2020.107658

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124720306112
  238. www.sciencedirect.com www.sciencedirect.com
    Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response
    1
    1. scibot 03 Sep 2020
      The Jackson LaboratoryStock# 002216

      DOI: 10.1016/j.ccell.2020.04.004

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      Curator: @ethanbadger

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      RRID:IMSR_JAX:002216
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    sciencedirect.com/science/article/pii/S1535610820302038
  239. www.sciencedirect.com www.sciencedirect.com
    Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function
    1
    1. scibot 03 Sep 2020
      The Jackson laboratory#002216

      DOI: 10.1016/j.cmet.2020.03.004

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1550413120301194
  240. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
    1
    1. scibot 03 Sep 2020
      Jax 002216

      DOI: 10.1016/j.celrep.2019.03.066

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      Curator: @bandrow

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    ncbi.nlm.nih.gov/pmc/articles/PMC6719696/
  241. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of autophagy in Cx3cr1+ mononuclear cells limits IL-23/IL-22 axis-mediated intestinal fibrosis
    1
    1. scibot 03 Sep 2020
      Stock #002216, Jackson laboratory

      DOI: 10.1038/s41385-019-0146-4

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      Curator: @bandrow

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      RRID:IMSR_JAX:002216 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC6927046/
  242. www.jci.org www.jci.org
    Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice
    1
    1. scibot 03 Sep 2020
      B6.129S7-Rag1tm1Mom/J

      DOI: 10.1172/JCI138697

      Resource: (IMSR Cat# JAX_002216,RRID:IMSR_JAX:002216)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:002216

      Curator comments: B6.129S7-Rag1tm1Mom/J Mus musculus IMSR Cat# JAX:002216

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      RRID:IMSR_JAX:002216 RRIDCUR:Missing
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    jci.org/articles/view/138697
  243. www.sciencedirect.com www.sciencedirect.com
    Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
    1
    1. scibot 03 Sep 2020
      Rag1–/–: B6.129S7-Rag1tm1Mom/J

      DOI: 10.1016/j.celrep.2020.107967

      Resource: (IMSR Cat# JAX_002216,RRID:IMSR_JAX:002216)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:002216

      Curator comments: B6.129S7-Rag1tm1Mom/J Mus musculus IMSR Cat# JAX:002216

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      RRID:IMSR_JAX:002216 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124720309487