48 Matching Annotations
  1. Jun 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Administration of Pgk1 missense mutation leads to more effective mitigation of neurodegenerative effects observed in ALS mice and transgenic zebrafish
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    sciencedirect.com/science/article/pii/S0753332226007109
  3. May 2026
  4. insight.jci.org insight.jci.org
    Reduced osteogenic factors and early osteoblast senescence in SOD1(G93A) ALS mouse model
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    insight.jci.org/articles/view/197475
  5. Apr 2026
  6. www.sciencedirect.com www.sciencedirect.com
    BDNF insufficiency exacerbates ALS progression
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    sciencedirect.com/science/article/pii/S2666379126001758
  7. Mar 2026
  8. www.sciencedirect.com www.sciencedirect.com
    Targeting PGAM5-driven mitochondrial integrated stress response slows ALS progression across subtypes
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    sciencedirect.com/science/article/pii/S0896627326000863
  9. Jan 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Apolipoprotein A1 reduces blood–spinal cord barrier leakage, improves astrocytic coverage, and enhances motor neuron survival to restore the neurovascular unit in ALS mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12832854/
  11. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202514128
  12. Nov 2025
  13. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    A 16-amino acid peptide delays the progression of motor neuron degeneration and pathogenic symptoms in ALS models
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    sciencedirect.com:5037/science/article/pii/S1878747925002843
  14. Oct 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TSPO Expression and [18F]DPA‐714 PET/CT Imaging as Pathogenetic and Diagnostic Biomarkers in Symptomatic Stages of Skeletal Muscle Fiber Degeneration in SOD1‐G93A ALS Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12519919/
  16. Jul 2025
  17. www.biorxiv.org www.biorxiv.org
    Targeting Neuromuscular Junction Regeneration is a Therapeutic Strategy in ALS
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    biorxiv.org/content/10.1101/2025.07.13.664600v1
  18. www.sciencedirect.com www.sciencedirect.com
    A mechanistic basis of fast myofiber vulnerability to neuromuscular diseases
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    sciencedirect.com/science/article/pii/S2211124725007302
  19. May 2025
  20. 52.53.155.43 52.53.155.43
    1-s2.0-S1525001625003806-main-html.html
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    52.53.155.43/1f8027de8a77cdc6b8dd6c2280a8a83083808fa3/1-s2.0-S1525001625003806-main-html.html
  21. Mar 2025
  22. www.sciencedirect.com www.sciencedirect.com
    Secreted neurofilament light chain after neuronal damage induces myeloid cell activation and neuroinflammation
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    sciencedirect.com/science/article/pii/S2211124725001536
  23. Feb 2025
  24. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17448
  25. 52.53.155.43 52.53.155.43
    Acute Viral Infection Accelerates Neurodegeneration in a Mouse Model of ALS
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    52.53.155.43/092e20e743f7aa0c65579e6270e39a6921c10b64/2024.09.17.613525.full-html.html
  26. Jan 2025
  27. www.nature.com www.nature.com
    Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS)
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    nature.com/articles/s41467-024-51578-1
  28. www.sciencedirect.com www.sciencedirect.com
    Polyamine metabolism dysregulation contributes to muscle fiber vulnerability in ALS
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    sciencedirect.com/science/article/pii/S2211124724014748
  29. Dec 2024
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength
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    pmc.ncbi.nlm.nih.gov/articles/PMC5919779/
  31. www.sciencedirect.com www.sciencedirect.com
    Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration
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    sciencedirect.com/science/article/pii/S2211124724013974
  32. www.sciencedirect.com www.sciencedirect.com
    Protocol for handling and using SOD1 mice for amyotrophic lateral sclerosis pre-clinical studies
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    sciencedirect.com/science/article/pii/S2666166724006245
  33. Sep 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response
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    sciencedirect.com/science/article/pii/S2211124724010702
  35. Aug 2024
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Identification of B6SJL mSOD1G93A mouse subgroups with different disease progression rates
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    onlinelibrary.wiley.com/doi/10.1002/cne.23814/full
  37. May 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OSMR is a potential driver of inflammation in amyotrophic lateral sclerosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11090450/
  39. Sep 2023
  40. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Identifying potential imaging markers for diffusion property changes in a mouse model of amyotrophic lateral sclerosis: Application of the continuous time random walk model to ultrahigh b-value diffusion-weighted MR images of spinal cord tissue
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/nbm.5037
  41. Jun 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Altered Sensory Neuron Development in CMT2D Mice Is Site-Specific and Linked to Increased GlyRS Levels
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    ncbi.nlm.nih.gov/pmc/articles/PMC7431706/
  43. Jan 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglial Expression of the Wnt Signaling Modulator DKK2 Differs between Human Alzheimer’s Disease Brains and Mouse Neurodegeneration Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC9836029/
  45. Dec 2022
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutant SOD1 aggregates formed in vitro and in cultured cells are polymorphic and differ from those arising in the CNS
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    pmc.ncbi.nlm.nih.gov/articles/PMC10099669/
  47. Aug 2022
  48. www.embopress.org www.embopress.org
    Impaired disassembly of the axon initial segment restricts mitochondrial entry into damaged axons
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    embopress.org/doi/10.15252/embj.2021110486
  49. Mar 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Excessive release of inorganic phosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons
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    sciencedirect.com/science/article/pii/S0896627322001489
  51. Jan 2022
  52. www.nature.com www.nature.com
    Upper motor neurons are a target for gene therapy and UCHL1 is necessary and sufficient to improve cellular integrity of diseased upper motor neurons
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    nature.com/articles/s41434-021-00303-4
  53. Sep 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK
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    sciencedirect.com/science/article/pii/S1097276521006924
  55. Aug 2021
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/full/10.1002/cne.23814
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5308886/
  58. Jul 2021
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ROCK inhibition improves axonal regeneration in a preclinical model of amyotrophic lateral sclerosis
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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24679
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/abs/10.1002/cne.24679
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5919779/
  62. May 2021
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nuclear lipidome is altered in amyotrophic lateral sclerosis: a pilot study
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15373
  64. Sep 2020
  65. elifesciences.org elifesciences.org
    Relaxation of synaptic inhibitory events as a compensatory mechanism in fetal SOD spinal motor networks
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    elifesciences.org/articles/51402
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Wild‐type and Mutant SOD1 Localizes to RNA‐Rich Structures in Cells and Mice But Does Not Bind RNA
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15126
  67. Jan 2020
  68. elifesciences.org elifesciences.org
    Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA
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    elifesciences.org/articles/49175
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a resilient mouse facial motoneuron population following target disconnection by injury or disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC6373730/
  70. www.sciencedirect.com www.sciencedirect.com
    Mir-17∼92 Confers Motor Neuron Subtype Differential Resistance to ALS-Associated Degeneration
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    sciencedirect.com/science/article/pii/S1934590919301651
  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ROCK inhibition improves axonal regeneration in a preclinical model of amyotrophic lateral sclerosis
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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24679
  72. Nov 2018
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stage-dependent remodeling of projections to motor cortex in ALS mouse model revealed by a new variant retrograde-AAV9
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    ncbi.nlm.nih.gov/pmc/articles/PMC6125125/
  74. elifesciences.org elifesciences.org
    Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS
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    elifesciences.org/articles/30955
  75. www.sciencedirect.com www.sciencedirect.com
    Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength
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    sciencedirect.com/science/article/pii/S0896627318301879
  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Screening the expression characteristics of several miRNAs in G93A‐SOD1 transgenic mouse: altered expression of miRNA‐124 is associated with astrocyte differentiation by targeting Sox2 and Sox9
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14229/full
  77. Nov 2017
  78. www.sciencedirect.com www.sciencedirect.com
    Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes
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    sciencedirect.com/science/article/pii/S0896627316310078
  79. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Identification of B6SJL mSOD1G93A mouse subgroups with different disease progression rates
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    onlinelibrary.wiley.com/doi/10.1002/cne.23814/full